• 보건행정학회지
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• 제9권2호
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• pp.118-138
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• 1999

This study presents the variations on drug utilization for outpatients' URI, gastritis. and hypertension by the type of hospital- tertiary hospital. general hospital. hospital. clinic. It investigated drug expenses. daily drug expenses. days of medication. the highest price of the drugs used. and the number of the different drugs used for each disease and type of hospital. This study also performed analysis to see how much the variations of variables related to drug use affect the variations of drug expenses. The dependent variable was drug expenses and the independent variables were days of medication. the average price of the drugs used. and the number of the different drugs used. Analysis of the drug utilization was performed on NFMI(National Federation of Medical Insurance) 1994 medical expense claim data. Patients with secondary diseases were excluded. In this study. 379 patients with URI, 386 patients with gastritis. 1.257 patients with hypertension were included. It was founded that there were large variation on drug utilization between the types of hospital for same diseases. Days of medication were longest in tertiary hospitals and shortest in hospitals or clinics. Clinics showed the lowest daily drug expenses in all of the diseases investigated. Daily drug expenses were highest in general hospitals or hospitals. which also tended to use drugs of higher price than other types of hospital. General hospitals and hospitals had larger variations in daily drug expenses and the highest price of drugs. It suggested that drug might be utilized overly in general hospitals and hospitals and some other factors might influence on drug utilization in these hospitals. It was found that the variations of drug expenses were affected by the variations of drug price and days of medication rather than the number of the different drugs. Then the strategy to reduce the variations of drug utilization and to improve the quality of drug utilization should focus on the drug price and days of medication. Further study is needed to assess the quality as well as the variation of drug utilization and to show the factors which affect them.

• 한국환경보건학회지
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• 제13권2호
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• pp.83-90
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• 1987

The objective of this study is to review the basic theories related substrate removal in wastewater flow variations using submerged biofilm reactor. An aerated biofilm reactor is that in which influent organic substrates are aerobically oxidized by the microorganisms of biofilm grown on the surface of submerged media. No sludge is returned, and oxygen is supplied by diffusers. Three types of aerated biofilm reactor are one stage-central aeration, one stageup flow aeration and two stage-side aeration. The orders of substrate removal capacity in wastewater flow variations showed two stage-side aeration, one stage-upflow aeration and one stage-central aeration. The phenonmenon of nonclosing volid in upflow aeration type was superior to these in central-side aeration type. Attached biofilm masses in case of upflow, side and central aeration reactor were 1.0mg/cm$^2$, 4.1 mg/cm$^2$ and 0.93 mg/cm$^2$, respectively. Yield coefficient for biofilm was 0.31 to 0.48. Especially, removal efficiency can be increased remarkably according to the number of biofilm reactor and the packed condition of media.

• Advances in environmental research
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• 제2권2호
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• pp.99-118
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• 2013

Rainwater runoff has been identified as a significant source of contaminants having tremendous impact on the receiving aquatic environment. In the present study, trace element transport by the surface runoff in the predominantly urban catchment of Guwahati city, India was monitored with a view to determine the chemical denudation rates of the land surface. A number of trace metals, namely Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb and Zn were measured in the runoff after 70 major rain events within the city. Cadmium was found to be the least abundant metal and Iron was the most abundant metal in the runoff. The results are interpreted on the basis of temporal and spatial variations in their concentrations. These variations are quite large in some of the events and reflect changes in the local environmental setting, differences in water utilization, variations in runoff volume, gradient and quality.

• 천문학회보
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• 제36권1호
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• pp.28.2-28.2
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• 2011

To search for and study the nature of the long-periodic variations of massive stars, we have been carrying out a precise radial velocity (RV) survey for supergiants. Here, we present high-resolution RV measurements of ${\alpha}$ Per which lies near the Cepheid instability strip from November 2005 to February 2011 using the fiber-fed Bohyunsan Observatory Echelle Spectrograph (BOES) at Bohyunsan Optical Astronomy Observatory (BOAO). The orbital solution yields a period of 129 days, a 2K amplitude of 80 m/s, and an eccentricity of 0.1. Assuming a possible stellar mass of 7.3 $M{\bigodot}$, we estimate the minimum mass for the planetary companion to be 7.5 MJup with the orbital semi-major axis of 0.97 AU. We do not find the correlation between RV variations and chromospheric activity indicator (Ca II H & K region). The Hipparcos photometry and bisector velocity span (BVS) do not show any obvious correlations with RV variations. These analyses suggest that ${\alpha}$ Per is a pulsating supergiant that hosts an exoplanet. If the 129 days variations of ${\alpha}$ Per do not come from an exoplanet but Cepheid-like pulsations, the theoretical boundary of the Cepheid instability strip may need to be extended to the bluer side.

• 대기
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• 제25권2호
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• pp.235-248
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• 2015

In this study, we analyzed the three dimensional variations (latitude, longitude, and height of Jet core) and wind speed of upper Jet stream in the East Asian region using recent 35 years (1979~2013) of four reanalysis data (NCEP-R2, MERRA, ERA-Interim. and JRA-55). Most of Jet core is located in $30.0{\sim}37.5^{\circ}N$ and $13.0{\sim}157.5^{\circ}E$ although there are slight differences among the four reanalysis data. The wind speed differences among reanalysis are about $3m\;s^{-1}$ regardless of seasons, the weakest in NCEP-R2 and the strongest in JRA-55. Although significance level is not high, most of reanalysis showed that the Jet core has a tendency of southward moving during spring and winter, but moving northward during summer and fall. This amplified seasonal variation of Jet core suggests that seasonal variations of weather/climate can be increased in the East Asian region. The longitude of Jet core has a tendency of systematically westward moving and decreasing of zonal variations regardless of averaging methods and reanalysis data. In general, the Jet core shows a tendency of moving south-west-ward and upward, getting intensified during spring and winter regardless of the reanalysis data. However, the Jet core shows a tendency of moving westward and downward, and getting weakened during summer. In fall, there were no distinctive trends not only in wind speed but also three dimensional locations compared to other seasons. Although the significance levels are not high and variation patterns are slightly different according to the reanalysis data, our findings are more or less different from the previous results. So, more works are needed to clarify the three dimensional variation patterns of Jet core over the East Asian region as a result of global warming.

• Ocean and Polar Research
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• 제34권2호
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• pp.201-218
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• 2012

The purpose of this study is to investigate climatological variations from the sea surface temperature (SST), chlorophyll-a concentration (Chl-a), and phytoplankton size class (PSC), using NOAA AVHRR, SeaWiFS, and MODIS data in the South Sea of Korea (SSK) and East China Sea (ECS). 26-year monthly SST and 13-year monthly Chl-a and PSC data, separated by whole and nine-different areas, were used to understand seasonal and inter-annual variations. SST and Chl-a clearly showed seasonal variations: higher SST and Chl-a were observed during the summer and spring, and lower values occurred during the winter and summer. The annual and monthly SST over 26 years increased by $0.2{\sim}1.0^{\circ}C$. The annual and monthly Chl-a concentration over 13 years decreased by $0.2{\sim}1.1mg/m^3$. To determine more detailed spatial and temporal variations, we used the combined data with monthly SST, Chl-a, and PSC. Between 1998 and 2010, the inter-annual trend of Chl-a decreased, with decreasing micro- and nano-size plankton, and increasing pico-size plankton. In regional analysis, the west region of the study area was spatially and temporally correlated with the area dominated by decreasing micro-size plankton; while the east region was less sensitive to coastal and land effects, and was dominated by increasing pico-size plankton. This phenomenon is better related to one or more forcing factors: the increased stratification of ocean driven by changes occurring in spatial variations of the SST caused limited contributions of nutrients and changed marine ecosystems in the study area.

• 대한의생명과학회지
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• 제24권3호
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• pp.221-229
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• 2018

Trichophyton rubrum is one of the well-known pathogenic fungi and causes dermatophytosis and cutaneous mycosis in human world widely. However, there are not an available sequence type (ST) classification methods and previous studies for T. rubrum until now. Therefore, currently, molecular biological tools using their DNA sequences are used for genotype identification and classification. In the present study, in order to characterize the genetic diversity and the phylogenetic relation of T. rubrum clinical isolates, five different housekeeping genes, such as actin (ACT), calmodulin (CAL), RNA polymerase II (RPB2), superoxide dismutase 2 (SOD2), and ${\beta}$-tubulin (BT2) were analyzed using by multilocus sequence typing (MLST). Also, DNA sequence analysis was performed to examine the differences between the sequences of Trichophyton strains and the identified genetic variations sequence. As a result, most of the sequences were shown to have highly matched rates in their housekeeping genes. However, genetic variations were found on three different positions of ${\beta}$-tubulin gene and were shown to have changed from $C{\rightarrow}G$ (1766), $G{\rightarrow}T$ (1876), and $C{\rightarrow}A$ (1886). To confirm the association with T. rubrum inheritance, a phylogenetic tree analysis was performed. It was classified as four clusters, but there was little significant correlation. Even so, MLST analysis is believed to be helpful for determining the genetic variations of T. rubrum in cases where there is more large-scale data accumulation. In conclusion, the present study demonstrated the first MLST analysis of T. rubrum in Korea and explored the possibility that MLST could be a useful tool for studying the epidemiology and evolution of T. rubrum through further studies.

• 전력전자학회논문지
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• 제20권2호
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• pp.152-159
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• 2015

In a weak grid condition, the precise grid impedance estimation is essential to guaranteeing the high performance current control and power transfer for a grid-connected inverter. This study proposes a precise estimation method for grid impedance by PQ variations by employing the variation method of reference currents. The operation principle of grid impedance estimation is fully presented, and the negative impact of the phase locked loop is analyzed. Estimation error by a synchronization angle in the park's transformation using the phase locked loop is derived. As a result, the variation method of reference currents for accurate estimation is introduced. The validation of the proposed method is verified through several simulation results and experiments based on a 2-kW voltage source inverter prototype.

• Journal of Astronomy and Space Sciences
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• 제8권2호
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• pp.149-158
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• 1991

Sixteen unitary Light curves of AR Lac in B and V are made at Yonsei University Observatory in the period of 1980-1988. Some overview findings of light variations are made. (1) The light variation outside eclipse follow none of the wave migration patterns reported by previous investigators. (2) Complicated shapes outside eclipse are apparently much reduced in the light curves of 1983-1984. This suggests than, in the future, AR Lac has a chance to attain a normal state with no complicated interactions. (3) The depths of the primary and the secondary mid-eclipses are changing year-to-year. (4) The K0 star, the larger component, has brightened by $0.^m$ 14 in V, while the G2 star has shown a fluctuation of about $0.^m$05 in V. (5) The B-V values at primary mid-eclipse have no correlation with the depth variations. (6) Independently of the increase of maximum brightness, the B-V colors in the non-eclipsed phases changed slightly over the years.

• 천문학회보
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• 제44권2호
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• pp.48.3-48.3
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• 2019

In the early stages of star formation, a protostar is deeply embedded in an optically thick envelope such that it is not directly observable. Variations in the protostellar accretion rate, however, will cause luminosity changes that are reprocessed by the surrounding envelope and are observable at submillimeter wavelengths. We searched for submillimeter flux variability toward 12 Planck Galactic Cold Clumps detected by the James Clerk Maxwell Telescope (JCMT)-SCUBA-2 Continuum Observations of Pre-protostellar Evolution (SCOPE) survey. These observations were conducted at 850 ㎛ using the JCMT/SCUBA-2. Each field was observed three times over about 14 months between 2016 April and 2017 June. We applied a relative flux calibration and achieved a calibration uncertainty of ~3.6% on average. We identified 136 clumps across 12 fields and detected four sources with flux variations of ~30%. For three of these sources, the variations appear to be primarily due to large-scale contamination, leaving one plausible candidate.