• 핵의학기술
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• 제27권1호
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• pp.47-54
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• 2023

Purpose PET-CT imaging require an appropriate quality assurance system to achieve high efficiency and reliability. Quality control is essential for improving the quality of care and patient safety. Currently, there are performance evaluation methods of UN2-1994 and UN2-2001 proposed by NEMA and IEC for PET-CT image evaluation. In this study, we compare phantom images with the same experiments before and after PET-CT 3D normalization and well counter correction and evaluate the usefulness of quality control. Materials and methods Discovery 690 (General Electric Healthcare, USA) PET-CT equiptment was used to perform 3D normalization and well counter correction as recommended by GE Healthcare. Based on the recovery coefficients for the six spheres of the NEMA IEC Body Phantom recommended by the EARL. 20kBq/㎖ of ¹⁸F was injected into the sphere of the phantom and 2kBq/㎖ of ¹⁸F was injected into the body of phantom. PET-CT scan was performed with a radioacitivity ratio of 10:1. Images were reconstructed by appliying TOF+PSF+TOF, OSEM+PSF, OSEM and Gaussian filter 4.0, 4.5, 5.0, 5.5, 6.0, 6,5 mm with matrix size 128×128, slice thickness 3.75 mm, iteration 2, subset 16 conditions. The PET image was attenuation corrected using the CT images and analyzed using software program AW 4.7 (General Electric Healthcare, USA). The ROI was set to fit 6 spheres in the CT image, RC (Recovery Coefficient) was measured after fusion of PET and CT. Statistical analysis was performed wilcoxon signed rank test using R. Results Overall, after the quality control items were performed, the recovery coefficient of the phantom image increased and measured. Recovery coefficient according to the image reconstruction increased in the order TOF+PSF, TOF, OSEM+PSF, before and after quality control, RCmax increased by OSEM 0.13, OSEM+PSF 0.16, TOF 0.16, TOF+PSF 0.15 and RCmean increased by OSEM 0.09, OSEM+PSF 0.09, TOF 0.106, TOF+PSF 0.10. Both groups showed a statistically significant difference in Wilcoxon signed rank test results (P value<0.001). Conclusion PET-CT system require quality assurance to achieve high efficiency and reliability. Standardized intervals and procedures should be followed for quality control. We hope that this study will be a good opportunity to think about the importance of quality control in PET-CT

• 무역학회지
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• 제42권4호
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• pp.69-91
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• 2017

글로벌 경제위기 이후, 주요 국가들은 일자리 창출을 위한 '창업 활성화'와 '중소기업 육성'에 높은 우선순위를 두고 관련 정책을 추진하고 있다. 국내에서도 '일자리 창출' 실현에 있어 기술 경쟁력을 갖춘 중소기업의 역할이 대두됨에 따라 정책적 관심이 고조되고 있다. 특히 보건의료 산업은 특성상 산업화까지 오랜 시간이 필요하며, 유통구조가 복잡하므로 관계부처 및 관계기관의 공동 전략이 필수적인데, 그에 따른 정책적 지원의 부재로 인해 대부분 영세한 중소기업에 머물러 있고, 글로벌 역량 또한 미흡한 것이 현실로, 이에 정부 차원의 혁신적인 지원방안과 전략이 절실하다. 본 연구에서는 독일의 사례를 통해 보건의료 분야의 중소기업이 글로벌 강소기업으로 성장할 수 있도록 정부의 정책적 지원 방향을 제시하고자 하였다. 연구결과 강소기업을 독일의 사례와 같이 세계적 수준의 기술경쟁력을 갖춘 글로벌 히든챔피언 기업으로 성장시켜 국제경쟁력을 갖추고, 우수 중소기업의 강소기업화를 촉진할 수 있는 환경 조성 및 기술 개발이 중요하다는 것을 알 수 있었다. 향후 글로벌 시장에서 보건의료 분야의 제품 및 기술 경쟁력을 확보하고, 고용창출 효과 및 매출액·부가가치 등이 높은 수출 중심의 글로벌 강소기업을 육성하기 위해서는 실질적인 정책적 지원이 필요할 것이다.

• Korean Journal of Radiology
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• 제23권1호
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• pp.89-100
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• 2022

Objective: To improve the N biomarker in the amyloid/tau/neurodegeneration system by radiomics and study its value for predicting cognitive progression in individuals with mild cognitive impairment (MCI). Materials and Methods: A group of 147 healthy controls (HCs) (72 male; mean age ± standard deviation, 73.7 ± 6.3 years), 197 patients with MCI (114 male; 72.2 ± 7.1 years), and 128 patients with Alzheimer's disease (AD) (74 male; 73.7 ± 8.4 years) were included. Optimal A, T, and N biomarkers for discriminating HC and AD were selected using receiver operating characteristic (ROC) curve analysis. A radiomics model containing comprehensive information of the whole cerebral cortex and deep nuclei was established to create a new N biomarker. Cerebrospinal fluid (CSF) biomarkers were evaluated to determine the optimal A or T biomarkers. All MCI patients were followed up until AD conversion or for at least 60 months. The predictive value of A, T, and the radiomics-based N biomarker for cognitive progression of MCI to AD were analyzed using Kaplan-Meier estimates and the log-rank test. Results: The radiomics-based N biomarker showed an ROC curve area of 0.998 for discriminating between AD and HC. CSF Aβ42 and p-tau proteins were identified as the optimal A and T biomarkers, respectively. For MCI patients on the Alzheimer's continuum, isolated A+ was an indicator of cognitive stability, while abnormalities of T and N, separately or simultaneously, indicated a high risk of progression. For MCI patients with suspected non-Alzheimer's disease pathophysiology, isolated T+ indicated cognitive stability, while the appearance of the radiomics-based N+ indicated a high risk of progression to AD. Conclusion: We proposed a new radiomics-based improved N biomarker that could help identify patients with MCI who are at a higher risk for cognitive progression. In addition, we clarified the value of a single A/T/N biomarker for predicting the cognitive progression of MCI.

• 한국병원경영학회지
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• 제23권1호
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• pp.41-50
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• 2018

The purpose of this research is to evaluate Brand Value by using the K-BPI(Korea Brand Power Index) of Korea Management Association which is based on consumer awareness, as well as to identify how Brand Value which is composed of top of awareness, unaided awareness, aided awareness, image, possibility of purchasing, preference, affects on the Market Share perceived by consumers. This research subjects were 10 hospitals with more than 1,000 beds in Seoul and Gyeonggi-do, and survey subjects were 20 or older adults living in the metropolitan area of Korea. Using K-BPI for measuring Brand Value and used calculation of Market Share according to consumer preference model for measuring Market Share. The major results of this research are as follows: First, this research identified that the top 5 hospitals of largest hospitals in metropolitan area measured by using K-BPI and Market Share were same hospitals as Big 4 hospitals of previous research evaluating the comprehensive competitiveness of hospitals and also same as hospitals that appeared recently. Second, Big 5 hospitals ranked first to fifth in both Brand Value and Market Share. To identify the relationship between K-BPI items(top of awareness, unaided awareness, aided awareness, image, availability, preference) and Market Share, multiple linear regression was used by dividing 5 upper and 5 lower group of hospitals per each. The group of 5 upper hospitals had a significant effect on Market Share, with 'top of awareness', 'unaided awareness', 'aided awareness'. The group of 5 lower hospitals had a significant effect on Market Share with 'unaided awareness', 'aided awareness'. The results of this study and hospitals of the first to third hospitals published in the K-BPI press release reported by KMAC in 2017, and the previous studies evaluating the comprehensive competitiveness hospitals, all had one thing in common that Big 4 hospitals ranked high position. This suggests that evaluation of Brand Value also can be a evaluation measure of hospital. A new competitiveness of hospital is expected by managing brand awareness to have a brand competitiveness and by securing intrinsic Market Share of consumer to reach hospital use ultimately.

• Pediatric Infection and Vaccine
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• 제24권3호
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• pp.134-140
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• 2017

목적: 중증복합면역결핍증(severe combined immunodeficiency [SCID])은 일차면역결핍증 중 가장 심각한 형태의 질병이다. 국내에서 SCID 선별검사를 확립하기 위하여, 신생아에게 T-cell receptor excision circle (TREC)/${\kappa}$-deleting recombination excision circle (KREC) 선별검사를 시행하고, 부모에게 인식도를 조사하였다. 방법: 혈액 검체에서 TREC/KREC을 multiplex 실시간중합효소연쇄반응으로 분석하였다. 부모에게 설문조사를 실시하였다. 결과: 141명의 신생아가 선별검사에 참여하였고, 140명(99.3%)이 첫 검사에서 TREC/KREC 양성이었으며, 한 명(0.7%)은 처음에 음성이었으나, 추후 양성으로 확인되었다. 인식도 조사에는 84% (141/168)는 SCID 선별검사가 국내에서도 시행되어야 한다고 답변했다. 결론: 본 연구에서는 국내에서 처음으로 신생아 SCID 선별검사와 인식도 시행되었으며, SCID 선별검사가 국내 임상에 적용될 수 있을 것으로 보인다.

• 디지털콘텐츠학회 논문지
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• 제9권1호
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• pp.27-31
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• 2008

u-Health는 유비쿼터스 IT의 대표적인 실현방식이며 우리 삶을 풍요롭게 만들 산업 영역으로 부각되고 있다. u-Health를 통하여 병원 중심의 진료라는 공간적 제약을 넘어, 생활과 진료공간을 자연스레 결합시키면서 일상 속에서 보편적 가치로 자리를 잡을 것이다. 이 논문에서 제안하는 시스템은 현제 진행 중인 u-Health 시대에 맞는 과학적이고 객관적인 지식으로 전문가의 도움을 받는 것과 동일한 효과를 얻을 수 있는 체계적이고 지능적인 휴대용 의료정보시스템을 제안하고자 한다. 휴대용 의료정보시스템은 의학적인 전문적인 지식을 요하는 문제의 해결에 필요한 경험, 지식 및 전문가의 의사결정 과정을 컴퓨터에 이식하고 이를 이용자가 이용함으로서 추론 과정을 거쳐 전문가의 견해를 제공받을 수 있다.

• 보건행정학회지
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• 제26권1호
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• pp.71-78
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• 2016

The value of using health insurance claim database is continuously rising in healthcare research. In studies where comorbidities act as a confounder, comorbidity adjustment holds importance. Yet researchers are faced with a myriad of options without sufficient information on how to appropriately adjust comorbidity. The purpose of this study is to assist in selecting an appropriate index, look back period, and data range for comorbidity adjustment. No consensus has been formed regarding the appropriate index, look back period and data range in comorbidity adjustment. This study recommends the Charlson comorbidity index be selected when predicting the outcome such as mortality, and the Elixhauser's comorbidity measures be selected when analyzing the relations between various comorbidities and outcomes. A longer look back period and inclusion of all diagnoses of both inpatient and outpatient data led to increased prevalence of comorbidities, but contributed little to model performance. Limited data range, such as the inclusion of primary diagnoses only, may complement limitations of the health insurance claim database, but could miss important comorbidities. This study suggests that all diagnoses of both inpatients and outpatients data, excluding rule-out diagnosis, be observed for at least 1 year look back period prior to the index date. The comorbidity index, look back period, and data range must be considered for comorbidity adjustment. To provide better guidance to researchers, follow-up studies should be conducted using the three factors based on specific diseases and surgeries.

• 패션비즈니스
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• 제20권2호
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• pp.1-15
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• 2016

Currently, a lot of people are aware of their health and well-being, so they are concerned about their healthcare. 'Taekwondo' is one of the popular sports that Korean people are passionate about Taekwondo has also become globalized. The uniform of Taekwondo is gaining importance. Taekwondo involves a lot of movement, hence the pattern should facilitate the movement. In addition Taekwondo uniform pattern should meet the demands of functionality, fit and consumer design preferences. This study aimed to provide the basic data for development of Taekwondo uniform pattern based on design preferences and functionality to wearer satisfaction. The result of this method indicated fit and design details. Also, the length of pants, top, and sleeve was too wide, which has to more fitted for both of genders. For females, the breakpoint was too low, which requires some increase to make females feel more secure. In conclusion, the results of this study indicated that in order to increase 'Takwondo' value, Taekwondo uniform is required to be more fashionable and comfortable to wear, which could influence other sports wear.

• Industrial Engineering and Management Systems
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• 제13권2호
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• pp.193-202
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• 2014

Patients' satisfaction while receiving medical service is affected by whether or not their preferences can be met, including time and physician preference. Due to scarcity of medical resource in China, efficient use of available resources is urgently required. To guarantee the utilization ratio, the scheduling decisions are made after all booking information is received. Two integer models with different objectives are formulated separately, maximizing the degree of satisfaction and revenue. The optimal value of the two models can be considered as the bound of corresponding objectives. However, it is improper to implement any of the extreme policies. Because revenue is a key element to keep the hospital running and satisfaction degree is related to the hospital's reputation, neither the revenue nor the satisfaction can be missed. Therefore, hospitals should make a balance. An integrated model is developed to find out the tradeoff between the two objectives. The whole degree of mismatching that is related to patient satisfaction and other separate mismatching degree are considered. Through a computational study, it is concluded that based on the proposed model hospitals can make their decisions according to service requirement.

• 보건의료산업학회지
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• 제12권3호
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• pp.13-26
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• 2018

Objectives: This study investigated how Korean daily newspapers frame the present government's health insurance coverage expansion policy, Moon Jae-in Care. Methods: A contents analysis was conducted to construct news frames represented in the four Korean daily newspapers' editorials and columns on Moon Jae-in Care during from April 2017 to April 2018. News text was classified into three different layers of frames: expressive element, narrative structure, and implied values. Results: The analysis revealed that the frequency of narrative frames was as follows: health system improvement (20.8%), public burden (14.6%), opposition by doctors (14.6%), and populism (12.5%). The financial sustainability accounted for 41.7% of the value frame, followed by procedural legitimation (18.8%), and coverage expansion (16.7%). The results also revealed that reported frames were different among newspapers: Chosun Ilbo tended to report in a negative tone, while Hankyoreh shinmun and Kyunghyang shinmun used a positive tone. Conclusions: This finding suggests that there are salient framings in reports on Moon Jae-in Care. Based on the results, the government needs to present a detailed financing plan on Moon Jae-in Care in detail. I discussed another implication of media frames results.