• 제목/요약/키워드: Value Assessment

검색결과 2,955건 처리시간 0.034초

Seven-day and In-hospital Mortality According to Left and Right Ventricular Dysfunction in Patients With Septic Shock

  • Sua Kim;Hyeri Seok;Beong Ki Kim;Yu Jin Kim;Seung Heon Lee;Je Hyeong Kim;Yong-Hyun Kim
    • Korean Circulation Journal
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    • 제53권12호
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    • pp.813-825
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    • 2023
  • Background and Objectives: The prognostic implications of septic cardiomyopathy have not been clearly demonstrated. We evaluated serial changes in left ventricular (LV) and right ventricular (RV) function in patients with septic shock and their prognostic value on 7-day and in-hospital mortality. Methods: Transthoracic echocardiography was performed within 48 hours of the diagnosis of septic shock and 7 days after the initial evaluation. In addition to traditional echocardiographic parameters, LV and RV function was evaluated using global longitudinal strain (GLS), and tricuspid annular plane systolic excursion (TAPSE). Results: A total of 162 patients (men, 83, 51.5%; 70.7±13.4 years; Acute Physiology and Chronic Health Evaluation [APACHE] II, 30.6±9.2) were enrolled. Initial GLS and TAPSE were -14.9±5.2% and 16.9±5.5 mm, and improved in the follow-up evaluation (GLS, -17.6±4.9%; TAPSE, 19.2±5.4 mm). Seven-day and in-hospital mortality were 24 (14.9%) and 64 (39.8%). Seven-day mortality was significantly associated with initial GLS >-16% (odds ratio [OR], 14.066, 95% confidence interval [CI], 1.178-167.969, p=0.037) and APACHE II score (OR, 1.196, 95% CI, 1.047-1.365, p=0.008). The in-hospital mortality of 7-day survivors was associated with follow-up TAPSE <16 mm (OR, 10.109, 95% CI, 1.640-62.322, p=0.013) and Sequential Organ Failure Assessment score (OR, 1.340, 95% CI, 1.078-1.667, p=0.008). GLS was not associated with in-hospital mortality of 7-day survivors. Conclusions: Fluctuation of both ventricular function was common in septic shock. Seven-day mortality of patients with septic shock was related to GLS, whereas in-hospital mortality of 7-day survivors was related to TAPSE, not to GLS.

Evaluation of Malignancy Risk of Ampullary Tumors Detected by Endoscopy Using 2-[18F]FDG PET/CT

  • Pei-Ju Chuang;Hsiu-Po Wang;Yu-Wen Tien;Wei-Shan Chin;Min-Shu Hsieh;Chieh-Chang Chen;Tzu-Chan Hong;Chi-Lun Ko;Yen-Wen Wu;Mei-Fang Cheng
    • Korean Journal of Radiology
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    • 제25권3호
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    • pp.243-256
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    • 2024
  • Objective: We aimed to investigate whether 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (2-[18F]FDG PET/CT) can aid in evaluating the risk of malignancy in ampullary tumors detected by endoscopy. Materials and Methods: This single-center retrospective cohort study analyzed 155 patients (79 male, 76 female; mean age, 65.7 ± 12.7 years) receiving 2-[18F]FDG PET/CT for endoscopy-detected ampullary tumors 5-87 days (median, 7 days) after the diagnostic endoscopy between June 2007 and December 2020. The final diagnosis was made based on histopathological findings. The PET imaging parameters were compared with clinical data and endoscopic features. A model to predict the risk of malignancy, based on PET, endoscopy, and clinical findings, was generated and validated using multivariable logistic regression analysis and an additional bootstrapping method. The final model was compared with standard endoscopy for the diagnosis of ampullary cancer using the DeLong test. Results: The mean tumor size was 17.1 ± 7.7 mm. Sixty-four (41.3%) tumors were benign, and 91 (58.7%) were malignant. Univariable analysis found that ampullary neoplasms with a blood-pool corrected peak standardized uptake value in earlyphase scan (SUVe) ≥ 1.7 were more likely to be malignant (odds ratio [OR], 16.06; 95% confidence interval [CI], 7.13-36.18; P < 0.001). Multivariable analysis identified the presence of jaundice (adjusted OR [aOR], 4.89; 95% CI, 1.80-13.33; P = 0.002), malignant traits in endoscopy (aOR, 6.80; 95% CI, 2.41-19.20; P < 0.001), SUVe ≥ 1.7 in PET (aOR, 5.43; 95% CI, 2.00-14.72; P < 0.001), and PET-detected nodal disease (aOR, 5.03; 95% CI, 1.16-21.86; P = 0.041) as independent predictors of malignancy. The model combining these four factors predicted ampullary cancers better than endoscopic diagnosis alone (area under the curve [AUC] and 95% CI: 0.925 [0.874-0.956] vs. 0.815 [0.732-0.873], P < 0.001). The model demonstrated an AUC of 0.921 (95% CI, 0.816-0.967) in candidates for endoscopic papillectomy. Conclusion: Adding 2-[18F]FDG PET/CT to endoscopy can improve the diagnosis of ampullary cancer and may help refine therapeutic decision-making, particularly when contemplating endoscopic papillectomy.

Value of Intraplaque Neovascularization on Contrast-Enhanced Ultrasonography in Predicting Ischemic Stroke Recurrence in Patients With Carotid Atherosclerotic Plaque

  • Zhe Huang;Xue-Qing Cheng;Ya-Ni Liu;Xiao-Jun Bi;You-Bin Deng
    • Korean Journal of Radiology
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    • 제24권4호
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    • pp.338-348
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    • 2023
  • Objective: Patients with a history of ischemic stroke are at risk for a second ischemic stroke. This study aimed to investigate the relationship between carotid plaque enhancement on perfluorobutane microbubble contrast-enhanced ultrasonography (CEUS) and future recurrent stroke, and to determine whether plaque enhancement can contribute to risk assessment for recurrent stroke compared with the Essen Stroke Risk Score (ESRS). Materials and Methods: This prospective study screened 151 patients with recent ischemic stroke and carotid atherosclerotic plaques at our hospital between August 2020 and December 2020. A total of 149 eligible patients underwent carotid CEUS, and 130 patients who were followed up for 15-27 months or until stroke recurrence were analyzed. Plaque enhancement on CEUS was investigated as a possible risk factor for stroke recurrence and as a possible adjunct to ESRS. Results: During follow-up, 25 patients (19.2%) experienced recurrent stroke. Patients with plaque enhancement on CEUS had an increased risk of stroke recurrence events (22/73, 30.1%) compared to those without plaque enhancement (3/57, 5.3%), with an adjusted hazard ratio (HR) of 38.264 (95% confidence interval [CI]:14.975-97.767; P < 0.001) according to a multivariable Cox proportional hazards model analysis, indicating that the presence of carotid plaque enhancement was a significant independent predictor of recurrent stroke. When plaque enhancement was added to the ESRS, the HR for stroke recurrence in the high-risk group compared to that in the low-risk group (2.188; 95% CI, 0.025-3.388) was greater than that of the ESRS alone (1.706; 95% CI, 0.810-9.014). A net of 32.0% of the recurrence group was reclassified upward appropriately by the addition of plaque enhancement to the ESRS. Conclusion: Carotid plaque enhancement was a significant and independent predictor of stroke recurrence in patients with ischemic stroke. Furthermore, the addition of plaque enhancement improved the risk stratification capability of the ESRS.

국가 생물다양성 전략 수립을 위한 OECMs의 가능성 탐구 - 당산목과 당산제를 중심으로 - (Exploring Other Effective Conservation Measures (OECMs) for Natural Heritage Sites - Focusing on the Dansanmok and Dansanje in Establishing the National Biodiversity Strategy and Action Plan -)

  • 이다영
    • 한국전통조경학회지
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    • 제41권3호
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    • pp.27-46
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    • 2023
  • 이 연구는 국가 생물다양성 전략 및 행동계획(NBSAP)을 수립하기 위해 자연유산에 OECMs(Other Effective Area-based Conservation Measures)을 적용하는 가능성을 탐구하였다. 자연유산 중 하나인 천연기념물 당산목과 관련된 생태적 특성과 문화적 특성을 조사하고 수집한 정보들을 종합하여 보전 가치를 확인하였고 IUCN의 개별 평가 도구 기준에 따라 대상지인 당산목이 당산제를 통해 지역공동체를 반영한 OECM으로 지정될 수 있는지 가능성을 검토하였다. 연구 결과, 당산목과 당산제는 후보 OECM으로 긍정적으로 평가되며, 국가 생물다양성 전략(NBSAP) 수립을 위한 전략에 있어서는 문화재청에서 실시하고 있는 '당산나무 할아버지 제도'와 '자연유산 민속행사 국고지원사업' 등이 지역 공동체를 자발적으로 참여시키는데 긍정적인 영향을 미친다는 결론을 내렸다. 따라서 이러한 결과를 토대로, 국가 생물다양성 전략(NBSAP) 수립을 위한 국가별 지표로서 당산목과 같은 자연성지가 생물다양성 보전을 위한 2030년 목표와 자연과 조화로운 삶을 위한 2050년 목표에 기여할 것으로 기대한다.

Assessment of the Severity of Coronavirus Disease: Quantitative Computed Tomography Parameters versus Semiquantitative Visual Score

  • Xi Yin;Xiangde Min;Yan Nan;Zhaoyan Feng;Basen Li;Wei Cai;Xiaoqing Xi;Liang Wang
    • Korean Journal of Radiology
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    • 제21권8호
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    • pp.998-1006
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    • 2020
  • Objective: To compare the accuracies of quantitative computed tomography (CT) parameters and semiquantitative visual score in evaluating clinical classification of severity of coronavirus disease (COVID-19). Materials and Methods: We retrospectively enrolled 187 patients with COVID-19 treated at Tongji Hospital of Tongji Medical College from February 15, 2020, to February 29, 2020. Demographic data, imaging characteristics, and clinical data were collected, and based on the clinical classification of severity, patients were divided into groups 1 (mild) and 2 (severe/critical). A semiquantitative visual score was used to estimate the lesion extent. A three-dimensional slicer was used to precisely quantify the volume and CT value of the lung and lesions. Correlation coefficients of the quantitative CT parameters, semiquantitative visual score, and clinical classification were calculated using Spearman's correlation. A receiver operating characteristic curve was used to compare the accuracies of quantitative and semi-quantitative methods. Results: There were 59 patients in group 1 and 128 patients in group 2. The mean age and sex distribution of the two groups were not significantly different. The lesions were primarily located in the subpleural area. Compared to group 1, group 2 had larger values for all volume-dependent parameters (p < 0.001). The percentage of lesions had the strongest correlation with disease severity with a correlation coefficient of 0.495. In comparison, the correlation coefficient of semiquantitative score was 0.349. To classify the severity of COVID-19, area under the curve of the percentage of lesions was the highest (0.807; 95% confidence interval, 0.744-0.861: p < 0.001) and that of the quantitative CT parameters was significantly higher than that of the semiquantitative visual score (p = 0.001). Conclusion: The classification accuracy of quantitative CT parameters was significantly superior to that of semiquantitative visual score in terms of evaluating the severity of COVID-19.

재제조품의 온실가스배출 저감효과 산정 표준화를 위한 핵심 요소 도출 (Key Elements for Standardizing the Estimation of Greenhouse Gas Emissions Reduction Induced by Remanufactured Products)

  • 김남석;배국표;노재학;강홍윤;황용우
    • 자원리싸이클링
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    • 제33권2호
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    • pp.62-72
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    • 2024
  • 기후 위기에 대응하고자 지난 2015년 파리협정에서 지구 온도상승을 2℃보다 아래로 유지하고 나아가 1.5℃ 아래로 억제하기 위한 목표를 설정하였음에도 불구하고, 지구 온도는 계속 상승 중에 있다. 실질적으로 이에 대응하기 위한 주요 전략으로 선진국들은 순환경제 실현을 제시하고 있으며, 세부 이행 방법으로는 재사용, 재제조, 재활용, 에너지 회수 등이 있다. 그중 재제조는 다른 자원순환 방법보다도 고부가가치 및 탄소중립 달성에 큰 잠재력을 가지고 있지만, 재제조를 통한 온실가스 저감효과를 정량적으로 평가할 수 있는 표준화된 방법이 부재한 상황이다. 이에 본 연구에서는 재제조에 의한 온실가스배출 감축효과 산정에 관한 2020년 이후의 최근 연구동향과 온실가스를 포함한 환경영향 평가 국제 표준 및 환경성적표지제도를 비교·분석함으로써 재제조품의 온실가스배출 저감효과 산정 표준화를 위한 핵심 요소를 도출하였다.

Assessment of stingless bee densification to improve pollination service: a case study in strawberry cultivation in field conditions

  • Priscila Silva Miranda;Zilda Cristina Malheiros Lima;Raquel Perez-Maluf;Paulo Henrique Marques Monroe;Aldenise Alves Moreira
    • Journal of Ecology and Environment
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    • 제48권2호
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    • pp.173-181
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    • 2024
  • Background: Pollination is an ecosystem service of utmost importance for agriculture. In this context, the study aimed to evaluate the pollination service of naturally occurring bees and after densification with colonies of stingless bees (Nannotrigona testceicornis and Tetragonisca angustula) in commercial strawberry plantation. The study was carried out in the four seasons of the year and under two experimental conditions: natural pollination (NP) and pollination under bee densification. The supply of flowers and bee density were estimated. For bee densification, four boxes of colonies of Iraí bees and four of Jataí bees were placed near the strawberry plantation. Five treatments were established for each condition, considering NP and pollination with bee densification on different days from flower anthesis, ranging from the 1st to the 5th day. Fruits were harvested, quantified, and submitted to evaluations to determine biometry, degree of deformity, and percentage of fertilized achenes. Results: There was a higher density in summer compared to other seasons in both conditions evaluated. The weight was greater (20.19 g) when fruits were pollinated on the first day after floral anthesis under pollination conditions with bee densification. It was observed that free pollination provided fruits with greater a greater of deformation of flowers on the fourth and fifth day after anthesis. However, when bee density became higher, the greatest degree of deformity was observed only in fifth-day fruits. The densification with stingless bees provided a 50% increase in the number of bees present on strawberry plants in summer and also a 15% increase in fruit weight and the occurrence of a lower degree of fruit deformity. Conclusions: Density with stingless bees provided a 50% increase in the number of bees present on strawberry plant in the summer, with an improvement in fruit quality and aggregate commercial value, providing a 15% increase in fruit weight and a lower degree of deformity under the conditions of densification of Iraí (N. testceicornis) and Jataí (T. angustula) bees. Under the evaluated conditions, the introduction of stingless bee boxes in the summer is recommended.

Assessment of planting soil temperature and growing degree day impacts on silage corn (Zea mays L.) biomass

  • Moonju Kim;Jiyung Kim;Mu-Hwan Jo;Kyungil Sung;Kun-Jun Han
    • Journal of Animal Science and Technology
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    • 제66권5호
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    • pp.949-961
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    • 2024
  • The annual forage crop production system, enclosing silage corn (Zea mays L.) and following cool-season annual forage, can enhance forage production efficiency where available land is limited for pasture production. In this forage production system, successful silage corn cultivation has a significant value due to the great yield of highly digestible forage. However, some untimely planting or harvesting of corn due to changing weather often reduces biomass and feeding values. Therefore, a study was conducted to quantify the corn silage biomass reductions by the deviations from optimum planting soil temperature and optimum growing degree day (GDD). The approximations of maximum corn production were estimated based on field trial data conducted between 1978 and 2018 with early, medium, and late-maturity corn groups. Based on weather data, the recorded planting dates and harvest dates were converted into the corresponding trials' soil temperatures at planting (STP) and the GDD. The silage corn biomass data were regressed against STP and GDD using a quadratic function. The maximum biomass point was modeled in a convex upward quadratic yield curve and the optimum STP and GDD were defined as those values at the maximum biomass for each maturity group. Optimized STP was at 16.6℃, 16.2℃, and 15.6℃ for early, medium, and late maturity corn groups, respectively, while optimized GDD at harvest was at 1424, 1363, and 1542℃. The biomass reductions demonstrated quadratic functions by the departures of STP or GDD. The 5% reductions were anticipated when STP departed from the optimum temperature by 2.2℃, 2.4℃, and 1.4℃ for early, medium, and late maturity corns, respectively; the same degree of reductions were estimated when the GDD departed by 200, 180, and 130℃ in the same order of the maturity groups. This result indicates that biomass reductions of late-maturity corn were more sensitive to the departures of STP or GDD than the early-maturity corn. Therefore, early maturing cultivars are more stable in biomass production in a silage corn-winter annual forage crop production system to enhance forage-based livestock production efficiency.

디지털 트랜스포메이션과 ESG 경영의 통합 추진을 위한 모델 개발에 관한 연구 (A Study on the Development of an Integrated Implementation Model for Digital Transformation and ESG Management)

  • 김승욱
    • 벤처혁신연구
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    • 제7권3호
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    • pp.85-100
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    • 2024
  • ESG 경영은 환경, 사회 및 거버넌스 요인을 고려하여 기업 경영을 추진하는 것을 의미하며 디지털 트랜스포메이션은 단순히 기존 업무의 자동화나 디지털화를 넘어서 업무 자체의 본질과 가치 창출 방식의 혁신적 변화를 추진한다. 따라서 디지털 트랜스포메이션은 기업이 ESG 목표를 달성하고 지속가능한 비즈니스 관행을 구현하는 데 도움이 될 수 있으며 디지털 트랜스포메이션과 ESG 경영은 기업의 지속가능성과 성장을 위해 상호 보완적인 관계를 맺고 있다. 이러한 관계는 디지털 트랜스포메이션과 ESG 경영 통합 추진의 시너지를 극대화하여 기업의 자원을 효율적으로 활용하고, 중복 투자를 방지함으로써 기업의 지속가능한 경영 성과를 향상시킬 수 있다. 이에 본 연구에서는 디지털 트랜스포메이션과 ESG 경영의 통합 추진을 위한 모델을 개발하기 위하여 우선적으로 양쪽이 연계된 비즈니스 프로세스 리엔지니어링(BPR)의 추진을 제안하였다. 이는 ESG 경영을 추진하기 위하여 다양한 데이터의 수집, 분석, 그리고 의사결정 과정이 디지털 트랜스포메이션 기술과 유기적으로 통합되어야 한다. 따라서 본 연구에서는 K-ESG 가이드라인에서 제시한 각각의 ESG 경영목표를 분석하고 이에 대응하는 적합한 디지털 트랜스포메이션 기술들을 전문가 인터뷰 및 선행 연구 결과를 통하여 도출하였다. K-ESG 가이드라인은 ESG 수준 자가 진단을 통해 ESG 성과 향상을 위한 개선과제 도출 및 목표에 의한 성과관리가 가능하다는 점에서 유용한 ESG 진단체계라고 할 수 있다. 디지털 트랜스포메이션과 ESG 경영의 통합 추진을 위하여 K-ESG 가이드라인을 기반으로 모델을 개발한 결과 기업들은 ESG 경영의 성과 향상과 디지털 혁신을 동시에 추진할 수 있는 통합모델을 활용하여 중복 투자나 시행착오를 줄일 수 있으며 기업의 다양한 자원을 효율적으로 활용할 수 있다. 따라서 본 연구는 구체적이며 실행 가능한 새로운 연구모델을 개발하여 연구자 및 기업에게 실무 및 학술적인 차원에서 시사점을 제공한다.

우즈베키스탄 섬유·패션 고등교육의 역량 강화를 위한 교육협력사업 수요조사 (Assessment of Educational Needs in Uzbekistan: For the Capacity Building in Textiles and Fashion Higher Education)

  • 조아라;이효정;진병호;이윤정
    • 한국가정과교육학회지
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    • 제35권3호
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    • pp.169-190
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    • 2023
  • 세계 5대 면화 생산국인 우즈베키스탄의 섬유·패션산업은 주로 원면 수출과 봉제산업에 중점을 두고 있다. 우즈베키스탄이 고부가가치를 달성하기 위해서는 CMT(cut, make and trim)단계에 있는 섬유·패션산업이 OEM(original equipment manufacturing), ODM(original design manufacturing), OBM(original brand manufacturing)으로 발전하는 것이 필수적이다. 한국은 우즈베키스탄을 잠재적인 제조기지이자 무역 파트너로서 인식하고 우즈베키스탄의 섬유 및 의류 분야의 발전을 위해 공적개발원조(ODA) 자금을 투입해 왔다. 본 연구는 글로벌 경쟁력의 맥락에서 우즈베키스탄의 패션 고등교육을 평가하고, 이 분야에서 한국 정부의 교육 ODA의 필요성과 전망을 측정하는 것을 목표로 한다. 우즈베키스탄의 현재 패션 교육 환경에 대한 종합적인 조사를 위하여 학계, 업계 전문가 및 정부 관계자의 설문조사, 개별 심층면접, 집단 심층면접법(Focus Group Interview) 등을 수행하였다. 연구 결과에 따르면 섬유 및 패션 부문이 우즈베키스탄 경제에 중추적인 역할을 하고 있음에도 불구하고 패션 고등교육 프로그램의 교육과정과 교수·학습방법에는 개선의 여지가 있는 것으로 나타났다. 본 연구는 교육 ODA 전략 수립을 위한 기초자료로서 의의를 갖는다.