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An Evaluation of the Anti-thrombosis and Antioxidant Activities of Different Parts of Dystaenia takeshimana (섬바디 부위별 추출물의 항혈전 및 항산화 활성)

  • Kang, Deok-Gyeong;Lee, Yun-Jin;Kim, Jong Sik;Sohn, Ho-Yong
    • Journal of Life Science
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    • v.32 no.4
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    • pp.303-309
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    • 2022
  • Dystaenia takesimana is an endemic plant found only in Korea, especially on Ulleung Island. The leaves and roots of D. takesimana have been used as food, forage, and oriental medicine. Anti-bacterial, anti-inflammation, antioxidant, and α-glucosidase inhibition biological activities have been reported in the plant's root extract. However, studies concerning the anti-thrombosis activities of D. takesimana are still in the rudimentary stage. In this study, the extracts of the leaf (DT-L), stem (DT-S), and root (DT-R) of D. takesimana were prepared using 70% ethanol, and their anti-thrombosis activities were evaluated. DT-L extracts (0.25 mg/ml) showed strong inhibitions against platelet aggregation, comparable to aspirin, with strong radical scavenging activities. Furthermore, the DT-L extract did not show any RBC hemolysis up to 1 m/ml. The ant-coagulation and antioxidant activities of the DT-S extract were ignorable. While the DT-R extract showed inhibitions against thrombin and blood coagulation factors, it also showed strong platelet aggregation. This is a first report of the anti-thrombosis activities of D. takesimana, and our results suggest that DT-L could be developed as a valuable bioresource for high value-added products.

Corneal Ulcer Region Detection With Semantic Segmentation Using Deep Learning

  • Im, Jinhyuk;Kim, Daewon
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.9
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    • pp.1-12
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    • 2022
  • Traditional methods of measuring corneal ulcers were difficult to present objective basis for diagnosis because of the subjective judgment of the medical staff through photographs taken with special equipment. In this paper, we propose a method to detect the ulcer area on a pixel basis in corneal ulcer images using a semantic segmentation model. In order to solve this problem, we performed the experiment to detect the ulcer area based on the DeepLab model which has the highest performance in semantic segmentation model. For the experiment, the training and test data were selected and the backbone network of DeepLab model which set as Xception and ResNet, respectively were evaluated and compared the performances. We used Dice similarity coefficient and IoU value as an indicator to evaluate the performances. Experimental results show that when 'crop & resized' images are added to the dataset, it segment the ulcer area with an average accuracy about 93% of Dice similarity coefficient on the DeepLab model with ResNet101 as the backbone network. This study shows that the semantic segmentation model used for object detection also has an ability to make significant results when classifying objects with irregular shapes such as corneal ulcers. Ultimately, we will perform the extension of datasets and experiment with adaptive learning methods through future studies so that they can be implemented in real medical diagnosis environment.

Development of Sub-indicator for Enhancing the Reliability of National-level Resource Productivity Estimation (국가 단위 자원생산성 측정 신뢰성 제고를 위한 보조지표 개발)

  • Lee, Jong-Hyo;Kang, Hong-Yoon;Hwang, Yong-Woo;Kwon, Soon-Gil
    • Clean Technology
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    • v.28 no.3
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    • pp.258-266
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    • 2022
  • Resource productivity (GDP/DMC) is defined as GDP divided by DMC. However, it has shortcomings when estimating the value-added generated from material processing. In this paper, an energy coefficient is applied to GDP to develop a sub-indicator (referred to as GDPe/DMC). Consequently, South Korea, which is a secondary industry-oriented country, created 1,094.60 USD/ton from input materials and was ranked 4th on the OECD list, which is 10 levels higher than the level estimated by GDP/DMC. However, Luxembourg, which is a tertiary industry-oriented country, is ranked 16th on the OECD list, which is 12 levels lower than the level estimated by GDP/DMC. The resource productivity estimated by the sub-indicator (GDPe/DMC) developed in this study indicates that secondary industry-oriented countries are undervalued in the existing main GDP/DMC calculation. On the other hand, tertiary industry-oriented countries are downgraded due to the industrial features of the GDPe/DMC calculation. As a result of this paper, GDPe/DMC could be considered a more reasonable indicator to directly reflect the material input effect compared to the existing main indicator, GDP/DMC. This means that GDPe/DMC-induced resource productivities could be estimated to be slightly higher than the GDP/DMC-induced resource productivities for secondary industry-oriented countries. It is expected that the sub-indicator, GDPe/DMC, proposed in this study could be useful especially for comparing and analyzing the resource productivities between countries that have different industry structures. This study intended to consider a structurally energy/resource-intensive industry in estimating and analyzing national-level resource productivity. Thus, the sub-indicator, GDPe/DMC, may help minimize the distortion of interpreting national resource productivities in various situations, and be utilized as a more efficient tool when used together with GDP/DMC.

A Study on Success Factors of Global Strategy of Cultural Content Company: Focusing on Iconix (문화콘텐츠기업 글로벌전략의 성공 요인에 관한 연구: 아이코닉스를 중심으로)

  • Han, JooHee;Choi, MyeongCheol;Zhang, MengTian
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.4
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    • pp.337-342
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    • 2021
  • The purpose of this study is to analyze the environment and strategic behaviors of cultural contents companies with a focus on Iconix, and to derive strategic recommendations for Iconix to pursue in order to create a sustainable competitive advantage. As a result of the analysis, Iconix is a vertically integrated development-business system from content planning to business in line with their mission to develop into an all-weather entertainment content provider that can confidently compete with the major players in the US and Europe that are already leading the global market. It is building a strong global business network covering both domestic and overseas markets in stages, taking a high-level global strategy. However, depending on Pororo's success or due to various problems within the organizational structure, it is facing limitations. Therefore, if the various strategic suggestions presented in this study are implemented based on the One Source Multi Channel/Multi Use strategy that can maximize the added value of contents through the participation and business linkage of leading companies in each sector of the entertainment industry, the total entertainment will be stabilized. It will establish itself as a leader in the contents industry.

Rice Cultivar Breeding for Rice Flour with Low Amylose by Tissue Culture (저아밀로스 특성 및 쌀가루 적합 벼 품종 육성)

  • Park, Jae-Ryoung;Kim, Eun-Gyeong;Jang, Yoon-Hee;Kim, Kyung-Min
    • Journal of Life Science
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    • v.32 no.9
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    • pp.698-705
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    • 2022
  • Rice consumption in Korea is continuously decreasing; therefore, methods for reducing rice stocks are now being proposed. Increasing the consumption of rice and reduce these stocks will require that the rice processing industry be developed beyond simply using cooked rice as food. The Korean people's eating habits have also diversified recently, and the consumption of bread is increasing. Therefore, breeding a cultivar for rice flour is now necessary. Here, a line suitable for processing into rice flour was cultivated by deriving a mutant line by tissue culture of Ilpum. Mutant populations were investigated for major agricultural traits in the field, and grain characteristics and endosperm characteristics were investigated after harvest. Among the lines, line 29111 had similar agricultural characteristics to the background Ilpum, and excellent grain quality, and was selected for further analysis. The physicochemical properties that determine taste were similar or improved. However, unlike Ilpum, 29111 had a non-uniform starch structure and a characteristic powdery endosperm because large and male starch grains are evenly distributed. Therefore, 29111 was viewed as a breeding line suitable for processing and for excellent agricultural characteristics and taste. The added value can be increased by diversifying the uses of rice. The taste was improved and a method for breeding cultivars with grain characteristics for glutinous rice that would satisfy both producers and consumers was presented.

Physicochemical properties of a calcium aluminate cement containing nanoparticles of zinc oxide

  • Amanda Freitas da Rosa;Thuany Schmitz Amaral;Maria Eduarda Paz Dotto;Taynara Santos Goulart;Hebert Luis Rossetto;Eduardo Antunes Bortoluzzi;Cleonice da Silveira Teixeira;Lucas da Fonseca Roberti Garcia
    • Restorative Dentistry and Endodontics
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    • v.48 no.1
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    • pp.3.1-3.14
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    • 2023
  • Objectives: This study evaluated the effect of different nanoparticulated zinc oxide (nano-ZnO) and conventional-ZnO ratios on the physicochemical properties of calcium aluminate cement (CAC). Materials and Methods: The conventional-ZnO and nano-ZnO were added to the cement powder in the following proportions: G1 (20% conventional-ZnO), G2 (15% conventional-ZnO + 5% nano-ZnO), G3 (12% conventional-ZnO + 3% nano-ZnO) and G4 (10% conventional-ZnO + 5% nano-ZnO). The radiopacity (Rad), setting time (Set), dimensional change (Dc), solubility (Sol), compressive strength (Cst), and pH were evaluated. The nano-ZnO and CAC containing conventional-ZnO were also assessed using scanning electron microscopy, transmission electron microscopy, and energy-dispersive X-ray spectroscopy. Radiopacity data were analyzed by the 1-way analysis of variance (ANOVA) and Bonferroni tests (p < 0.05). The data of the other properties were analyzed by the ANOVA, Tukey, and Fisher tests (p < 0.05). Results: The nano-ZnO and CAC containing conventional-ZnO powders presented particles with few impurities and nanometric and micrometric sizes, respectively. G1 had the highest Rad mean value (p < 0.05). When compared to G1, groups containing nano-ZnO had a significant reduction in the Set (p < 0.05) and lower values of Dc at 24 hours (p < 0.05). The Cst was higher for G4, with a significant difference for the other groups (p < 0.05). The Sol did not present significant differences among groups (p > 0.05). Conclusions: The addition of nano-ZnO to CAC improved its dimensional change, setting time, and compressive strength, which may be promising for the clinical performance of this cement.

Analysis of Chemical Components for Aerial and Underground Parts of Wild Ginseng and Evaluation of Skin Anti-aging Efficacy (야생 산삼 지상부 및 지하부의 화학성분 분석과 피부 항노화 효능 평가)

  • Seok-Seon Roh;Gwang Jin Lee;Byunghyun Kim;Bo Kyoung Hwang;Hyojin Kim;Yun Hee Chang;Jae-kun Yoou;Young-Sung Ju
    • The Korea Journal of Herbology
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    • v.38 no.5
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    • pp.85-95
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    • 2023
  • Objectives : This study was intended to reveal the chemical profiles of aerial(leaf, stem) and underground(rhizome, radix) parts of wild ginseng, and to investigate their anti-aging effects on human skin cells. Methods : Wild ginseng, estimated for over 20 years, was divided into the aerial and underground parts. Total phenolic contents of each extracts were measured using a Folin-ciocalteu method. The contents of 18 amino acids, 8 minerals and 27 ginsenosides were determined by GC-FID, ICP-MS and LC-MS, respectively. The anti-aging effects, including the radical scavenging activity, the activation of mitochondrial function on human fibroblasts, and the proliferation activity on human keratinocyte progenitor cells, for the whole plant and underground part of wild ginseng were evaluated. Results : The total phenolic acids, amino acids, and minerals in the aerial part were more than twice as high as in the underground part. Compared to the cultivated ginseng root, there were various types of ginsenosides in both parts of wild ginseng, and the total amount was more than twice as high. In particular, the aerial part significantly contained ginsenoside F1, F2, C-Mc1, and C-O, and the distinctive patterns that distinguish each parts of wild ginseng from the cultivated ginseng root were derived. The whole plant and underground part of wild ginseng exhibited significant antioxidant effect(14.3-45.6%), activation of mitochondrial membrane potential(105.5-120.1%), and cell proliferation(112.1-125.4%). Conclusions : The entire plant and underground part of wild ginseng are high value-added plants and have beneficial effects on skin anti-aging properties through its abundant metabolites.

Developing Indicators for Assessing the Quality of Universities Based on Comparative Analysis of Major approaches in Foreign Countries (주요국의 질 평가 접근법 비교분석에 기초한 대학의 질적 수준 평가 지표 개발)

  • Choi, Jeung-Yun;Jeong, Jinchul;Lee, Jung-Mi
    • Korean Journal of Comparative Education
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    • v.19 no.1
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    • pp.25-58
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    • 2009
  • This study aimed to establish a conceptual scheme of the quality of university and to develop a set of structured indicators for assessing the quality of university based on the result of comparative analysis of major approaches in foreign countries. Reviewing extensive literatures regarding the quality of higher education, a conceptual scheme of the quality of university, in which three representative approaches such as a goal-accomplishment approach, a customer-satisfaction approach, and a value-added approach were emphasized, was proposed and the quality of university was defined as a function of harmonization of input-process-output elements of universities. To develop indicators for assessing the quality of university, four types of approaches including university accreditation system, commercially-producted university ranking system, college student survey, and direct assessment of students' learning outcomes were reviewed. Finally thirteen sets of evaluation indicators out of six countries were comparatively analyzed. The analyses focused on the format, the content, and the primary concept of the quality in each instrument and a draft of the assessment indicators were structured. The draft of the assessment indicators were verified through a panel of professionals. The final indicators assessing the quality of university consist of three dimensions and seven areas. The input dimension comprised institutional goals, human resources, and physical resources. In the process dimension, curriculum and learning process areas were included. And, finally, the output dimension consists of educational outputs and research outputs. Based on the outcomes of the study, the recommendations were suggested for improving and utilizing the assessment indicators of the quality of university.

Prospect of Sustainable Organic Tea Farming in Lwang, Kaski, Nepa (네팔 르왕지역의 지속적 유기농차 재배 방향)

  • Chang, K.J.;Huang, D.S.;Park, C.H.;Jeon, U.S.;Jeon, S.H.;Binod, Basnet.
    • Journal of Practical Agriculture & Fisheries Research
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    • v.12 no.1
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    • pp.137-150
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    • 2010
  • Traditionally, like many people in mountain region of the Himalaya, the Lwang communities depend on mix of subsistence agriculture, animal husbandry, and seasonal migrant labor for their livelihoods. These traditional systems are characterized by low productivity, diverse use of available natural resources (largely for home consumption), limited markets, and some aversion for innovation. The potential to generate wealth through commerce has largely been untapped by these mountain residents and thus is undervalued in local and national economies. Introduction of organic tea farming is a part of Lwang community's several initiatives to break the vicious poverty cycle Annapurna Conservation Area Project (ACAP) played facilitating roles in all their efforts since beginning. In five years, the tea plantation emerged as a new means for secured a livelihood. This study aims to analyze the current practices in tea farming both in terms of farm management and soil nutrient status(technical) and the prosperity of the tea farmers (social). The technical aspect covers the soil and tea leaf analysis of various nutrients contents in the soil and tea leaf. Originally, the technical aspect of the study was not planned but later during the consultation with the advisor it was taken into consideration which added value to the research study. The sample were collected from different locations and analyzed on the field itself. The other part of the study i.e. the social aspect was done through questionnaire survey and focus group discussion. the tea farming provided them not only a new opportunity but also earned an identity in the region. This initiative was undertaken as a piloting measure. Now that the tea is in production with processing unit established locally, more serious consideration has to be given for better yield and economic prosperity. This research finding will help the community to analyze their efforts and make correction measures in tea garden management and application of fertilizer. It is also expected to fill up the gaps of knowledge and information required to reduce economic stresses and enhance capacity of farmers to make the tea farming a sustainable and beneficial business. The findings are expected to Sustainability of organic tea farming has direct impacts on biodiversity conservation compared to the other traditional farming practices that are more resource intensive. The study will also contribute to identify key action points required for reducing poverty while conserving environment and enhancing livelihoods

Analysis of Marketing Strategy in Domestic Online Luxury Fashion Platform (국내 온라인 명품 패션 플랫폼 마케팅전략 분석)

  • Min Gyung Lee;Hyeon Ju Kim
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.1
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    • pp.361-372
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    • 2023
  • In this study, three luxury fashion start-up platforms, Balaan, Trenbe, and Must-it, were selected as research subjects. The purpose of this study is to compare and analyze the marketing mix strategies of each of the three online sites. The results of our study are as follows. First of all, the product strategies of the three luxury platform companies are characterized by the composition of products from high-end brands to SPA brands, and product composition such as kids, home living, Used goods and art in addition to women's and men's wear. In addition, the pricing strategies of luxury platforms show price differences depending on the luxury platform even for the same product. It is shown as a structure that directly determines margin. Therefore, in order to secure an edge in price competitiveness, each platform provided discount coupons and savings that are not available in offline stores such as department stores, providing opportunities to purchase luxury goods at a lower price than offline stores.Lastly, the sales promotion strategies of the three luxury platform companies was used include price discount promotions such as price discounts, discount coupons, and regular sales, and value-added sales such as membership registration/review points, events, product information, delivery services, social contribution activities, and SNS utilization.