• Title/Summary/Keyword: Valuable material

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Bioactive Compounds, Anti-Oxidant Activities and Anti-Inflammatory Activities of Solvent Extracts from Centella asiatica Cultured in Chungju (충주산 병풀 용매추출물의 활성성분과 항산화 및 항염증 활성)

  • Shin, Hyun-Young;Kim, Hoon;Jeong, Eun-Jin;Kim, Jeung-Eun;Lee, Kyeong-Haeng;Bae, Yun-Jeong;Yu, Kwang-Won
    • The Korean Journal of Food And Nutrition
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    • v.33 no.6
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    • pp.692-701
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    • 2020
  • Centella asiatica (CA) has been widely used as herbal plants. It is a valuable resources. The aim of the present study was to evaluate physiological activities of solvent extracts from CA cultivated in Chungju, Korea (Good tiger care). After preparing water (cold-water, CA-WE; hot-water, CA-HWE) and EtOH extracts (50% EtOH, CA-50E; 70% EtOH, CA-70E), their total polyphenol, flavonoid, and triterpenoid contents, and anti-oxidant activities, and anti-inflammatory activities were examined and compared. CA-70E showed the most potent anti-oxidant activity based on ABTS radical scavenging activity and reducing ability assays, while CA-50E and CA-70E showed the highest DPPH radical scavenging activity. Among major triterpenoid glycosides present in CA, madecassoside and asiaticoside contents were found to be the highest in CA-70E, and madecassic acid and asiatic acid were the highest in CA-50E. In LPS-stimulated RAW 264.7 cells, CA-70E showed the highest TNF-α inhibitory activity, although CA-50E and CA-70E similarly inhibited nitric oxide production. Ethanol extracts significantly inhibited IL-6 and IL-8 production more than water extracts using TNF-α/IFN-γ-stimulated HaCaT cells, indicating its better inhibitory against skin inflammation. Therefore, Chungju-CA EtOH extract, especially 70% EtOH extract, has high physiologically active ingredients and potent anti-oxidant and anti-inflammatory activities, suggesting its industrial application as a functional material.

Significance of Three-Dimensional Digital Documentation and Establishment of Monitoring Basic Data for the Sacred Bell of Great King Seongdeok (성덕대왕신종의 3차원 디지털 기록화 의미와 모니터링 기초자료 구축)

  • Jo, Younghoon;Song, Hyeongrok;Lee, Sungeun
    • Conservation Science in Museum
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    • v.24
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    • pp.55-74
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    • 2020
  • The Sacred Bell of Great King Seongdeok is required digital precision recording of conservation conditions because of corrosion and partial abrasion of its patterns and inscriptions. Therefore, this study performed digital documentation of the bell using four types of scanning and unmanned aerial vehicle (UAV) photogrammetry technologies, and performed the various shape analyses through image processing. The modeling results of terrestrial laser scanning and UAV photogrammetry were merged and utilized as basic material for monitoring earthquake-induced structural deformation because these techniques can construct mutual spatial relationships between the bell and its tower. Additionally, precision scanning at a resolution four to nine times higher than that of the previous study provided highly valuable information, making it possible to visualize the patterns and inscriptions of the bell. Moreover, they are well-suited as basic data for identifying surface conservation conditions. To actively apply three-dimensional scanning results to the conservation of the original bell, the time and position of any changes in shape need to be established by further scans in the short-term. If no change in shape is detected by short-term monitoring, the monitoring should continue in medium- and long-term intervals.

Correlation between Lithium Concentration and Ecotoxicoloigy in Lithium Contained Waste Water (리튬 함유 폐액에서의 리튬 농도와 생태독성과의 연관성 연구)

  • Jin, Yun-Ho;Kim, Bo-Ram;Kim, Dae-Weon
    • Clean Technology
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    • v.27 no.1
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    • pp.33-38
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    • 2021
  • Demand for lithium-based secondary batteries is greatly increasing with the explosive growth of related industries, such as mobile devices and electric vehicles. In Korea, there are several top-rated global lithium-ion battery manufacturers accounting for 40% of the global secondary battery business. Most discarded lithium secondary batteries are recycled as scrap to recover valuable metals, such as Nickel and Cobalt, but residual wastes are disposed of according to the residual lithium-ion concentration. Furthermore, there has not been an attempt on the possibility of water discharge system contamination due to the concentration of lithium ions, and the effluent water quality standards of public sewage treatment facilities are becoming stricter year after year. In this study, the as-received waste water generated from the cathode electrode coating process in the manufacturing of high-nickel-based NCM cathode material used for high-performance and long-term purposes was analyzed. We suggested a facile recycling process chart for waste water treatment. We revealed a correlation between lithium-ion concentration and pH effect according to the proposed waste water of each recycling process through analyzing standard water quality tests and daphnia ecological toxicity. We proposed a realistic waste water treatment plan for lithium electrode manufacturing plants via comparison with other industries' ecotoxicology.

Assessment of the Object Detection Ability of Interproximal Caries on Primary Teeth in Periapical Radiographs Using Deep Learning Algorithms (유치의 치근단 방사선 사진에서 딥 러닝 알고리즘을 이용한 모델의 인접면 우식증 객체 탐지 능력의 평가)

  • Hongju Jeon;Seonmi Kim;Namki Choi
    • Journal of the korean academy of Pediatric Dentistry
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    • v.50 no.3
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    • pp.263-276
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    • 2023
  • The purpose of this study was to evaluate the performance of a model using You Only Look Once (YOLO) for object detection of proximal caries in periapical radiographs of children. A total of 2016 periapical radiographs in primary dentition were selected from the M6 database as a learning material group, of which 1143 were labeled as proximal caries by an experienced dentist using an annotation tool. After converting the annotations into a training dataset, YOLO was trained on the dataset using a single convolutional neural network (CNN) model. Accuracy, recall, specificity, precision, negative predictive value (NPV), F1-score, Precision-Recall curve, and AP (area under curve) were calculated for evaluation of the object detection model's performance in the 187 test datasets. The results showed that the CNN-based object detection model performed well in detecting proximal caries, with a diagnostic accuracy of 0.95, a recall of 0.94, a specificity of 0.97, a precision of 0.82, a NPV of 0.96, and an F1-score of 0.81. The AP was 0.83. This model could be a valuable tool for dentists in detecting carious lesions in periapical radiographs.

Prompt engineering to improve the performance of teaching and learning materials Recommendation of Generative Artificial Intelligence

  • Soo-Hwan Lee;Ki-Sang Song
    • Journal of the Korea Society of Computer and Information
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    • v.28 no.8
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    • pp.195-204
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    • 2023
  • In this study, prompt engineering that improves prompts was explored to improve the performance of teaching and learning materials recommendations using generative artificial intelligence such as GPT and Stable Diffusion. Picture materials were used as the types of teaching and learning materials. To explore the impact of the prompt composition, a Zero-Shot prompt, a prompt containing learning target grade information, a prompt containing learning goals, and a prompt containing both learning target grades and learning goals were designed to collect responses. The collected responses were embedded using Sentence Transformers, dimensionalized to t-SNE, and visualized, and then the relationship between prompts and responses was explored. In addition, each response was clustered using the k-means clustering algorithm, then the adjacent value of the widest cluster was selected as a representative value, imaged using Stable Diffusion, and evaluated by 30 elementary school teachers according to the criteria for evaluating teaching and learning materials. Thirty teachers judged that three of the four picture materials recommended were of educational value, and two of them could be used for actual classes. The prompt that recommended the most valuable picture material appeared as a prompt containing both the target grade and the learning goal.

Basic Study on the Animation Culture Prototype: A Comparison of Korea and Japan (애니메이션에 나타난 문화원형에 관한 고찰: 한·일간 비교를 중심으로)

  • Kim, Yunho
    • Journal of International Area Studies (JIAS)
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    • v.16 no.2
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    • pp.73-94
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    • 2012
  • Recently, Japanese cultural contents are being evaluated as a worldwide content. Among them, the animation takes an overwhelming place in the world market as a Japanese representative content. We need to understand that Japanese animation is being recognized world wide, because Japanese culture was grafted in to and it's very important to apply that to our situation. Cultural content to dominate the world has a fundamentally characteristics derived from regional culture. Cultural content includes elements of particular culture prototype. To investigate into cultural content that has globally used and is valuable, in-depth and systematic research for local (country) culture prototype showed be carried out. Our research aim to provide basic data so Korean animation can be developed as axis of Korean Wave. This compares and analyzes the Culture prototype from Korea and Japanese modern civilized media animation. Specifically for the animation shown in the culture prototype, we aim to - Analyze the content of culture prototype shown in Korea's animation: 'Hopi and Chadol Bawi', 'Heung-Bu and Nol-Bu', 'A Admiral's Diary', and 'Oseam'. - Analyze the content of culture prototype shown in Japan's animation: 'Genji', 'The Spiriting away of Sen and Chihiro', 'The Princess Mononoke', and 'Raccoon War Pom Poko'. - Compare and analyze the content of culture prototype depending on classifying criteria shown between Korea and Japan. We finally want to provide the basic data to develop the creation material for the global animation content based on these two countries throughout this research.

Estimating the Economic Value of Securing the High Seas Marine Biological Resources Using the Contingent Valuation Method (조건부 가치측정법을 이용한 공해상 해양생명자원 확보의 경제적 가치 추정)

  • Se-Jun Jin;Young-Ju Kwon;Eun-Chul Choi
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.29 no.7
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    • pp.794-801
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    • 2023
  • The high seas, covering the majority of the world's oceans, hold invaluable marine resources crucial for the growth of the marine bio-industry. The High seas bioresources program of South Korea is at the forefront of these global efforts. This study aims to gauge public awareness and quantify the project benefits, offering insights for future policy decisions. The results revealed that the estimated annual average willingness to pay (WTP) was 3,778.8 KRW, equating to approximately 81.54 billion KRW when extrapolated to the entire national population. The implications of the study are twofold: The project benefits, based on WTP, are substantial, amounting to approximately 81.5 billion KRW annually. This provides critical reference material for future policy formulation, given the considerable WTP in comparison to the current investment. Although interest in international sea marine biological resources is growing, public awareness remains relatively low. However, the project plays a crucial role in building essential databases for the marine bio-industry and securing international sea marine biological resources. Public interest and sustained support are pivotal, not only for this project but also for future policy implementation. Strategies to enhance public awareness are essential, and the study results offer valuable input for future policy decisions.

A Study on the Prior Leaching and Recovery of Lithium from the Spent LiFePO4 Cathode Powder Using Strong Organic Acid (강유기산을 이용한 폐LiFePO4 양극분말로부터 리튬의 선침출에 대한 연구)

  • Dae-Weon Kim;Soo-Hyun Ban;Hee-Seon Kim;Jun-Mo Ahn
    • Clean Technology
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    • v.30 no.2
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    • pp.105-112
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    • 2024
  • Globally, the demand for electric vehicles has surged due to greenhouse gas regulations related to climate change, leading to an increase in the production of used batteries as a consequence of the battery life issue. This study aims to selectively leach and recover valuable metal lithium from the cathode material of spent LFP (LiFePO4) batteries among lithium-ion batteries. Generally, the use of inorganic acids results in the emission of toxic gases or the generation of large quantities of wastewater, causing environmental issues. To address this, research is being conducted to leach lithium using organic acids and other leaching agents. In this study, selective leaching was performed using the organic acid methane sulfonic acid (MSA, CH3SO3H). Experiments were conducted to determine the optimal conditions for selectively leaching lithium by varying the MSA concentration, pulp density, and hydrogen peroxide dosage. The results of this study showed that lithium was leached at approximately 100%, while iron and phosphorus components were leached at about 1%, verifying the leaching efficiency and the leaching rates of the main components under different variables.

A Study on General Contractors' Control Measures for Construction Cost Overrun (종합건설사 현장의 원가초과 억제 방안 분석에 관한 연구)

  • Park, Jee Young;Kim, Hyeon Jin;Kim, Han Soo
    • Korean Journal of Construction Engineering and Management
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    • v.25 no.3
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    • pp.27-36
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    • 2024
  • The effective control of cost overrun is a crucial issue for construction companies to secure profitability. Especially in situations where cost pressures are significant due to factors such as rising raw material prices and increased financial costs due to high-interest rate policies, cost overruns resulting from project failures have a highly detrimental impact on the profitability of construction firms. The objective of this study is to analyze the current status of cost overrun control measures adopted by construction companies using the IPA technique and provide key characteristics and implications. The IPA analysis results showed that practitioners in general contractors exhibit a high level of interest and effort regarding cost overrun while the performance level is relatively low. Nevertheless, the measures considered important to control cost overruns generally show a high tendency for execution as well. Cost overrun control measures that show high importance but low execution are primarily related to collaboration and communication sectors. To effectively control cost overruns, enhancing collaboration and communication with construction supervisors/CM, headquarters, and regulatory authorities emerged as the most urgent need. Through this study, the current status and areas for improvement regarding cost overrun control measures in general contractors can be identified. This can be valuable for deriving directions and enhancements for future cost overrun control strategy development.

Verification of the effect of Potentillae Chinensis Chinensis Herba extract and bioconversion fraction on chronic respiratory diseases (위릉채 추출물 및 생물전환 분획물의 만성호흡기 질환 효과 검증)

  • Dong-Hee Kim;Bo Ae Kim;Yun-Hwan Kang
    • Journal of the Korean Applied Science and Technology
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    • v.40 no.6
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    • pp.1454-1463
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    • 2023
  • Evaluating the antioxidant efficacy using Potentillae Chinensis Herba extract, the anti-inflammatory efficacy was tested in respiratory mucosal epithelium, RAW264.7 cells, and zebrafish. As a result, antioxidant activity increased in a concentration-dependent manner in DPPH free radical scavenging and ABTS+ cation radical activities. As a result of MTT assay for cell experiments, the survival rate of NCI-H292 cells was reduced to less than 70% when treated at each concentration of 100 ㎍/ml, subsequent experiments were conducted at 50 ㎍/ml. Anti-inflammatory efficacy evaluation, NO production, TNF-𝛼, IL-1𝛽, and PGE2 decreased, and COX-2 also decreased significantly at 50 ㎍/ml. The mucin protein expression of Potentillae Chinensis Herba extract and bioconverted extract, it was observed that MUC5AC expression was significantly reduced. In the zebrafish toxicity evaluation, concentrations below 50 ㎍/ml did not show embryotoxicity and showed anti-inflammatory efficacy by reducing NO production due to LPS. The above results are valid to be valuable for use as a functional material that suppresses inflammation by helping the expression of Potentillae Chinensis Herba's respiratory mucus proteins.