• Asian Pacific Journal of Cancer Prevention
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• 제17권6호
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• pp.2805-2810
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• 2016

Background: Differentiated thyroid cancer is the most common endocrine malignancy with a generally good prognosis. Knowing long-term outcomes of each patient helps management planning. The study was conducted to develop and validate a clinical prognostic score for predicting disease remission in patients with differentiated thyroid cancer based on patient, tumor and treatment factors. Materials and Methods: A retrospective cohort study of 1,217 differentiated thyroid cancer patients from two tertiary-care hospitals in the Northeast of Thailand was performed. Associations between potential clinical prognostic factors and remission were tested by Cox proportional-hazards analysis in 852 patients (development cohort). The prediction score was created by summation of score points weighted from regression coefficients of independent prognostic factors. Risks of disease remission were estimated and the derived score was then validated in the remaining 365 patients (validation cohort). Results: During the median follow-up time of 58 months, 648 (76.1%) patients in the development cohort had disease remission. Five independent prognostic factors were identified with corresponding score points: duration from thyroid surgery to $^{131}I$ treatment (0.721), distant metastasis at initial diagnosis (0.801), postoperative serum thyroglobulin level (0.535), anti-thyroglobulin antibodies positivity (0.546), and adequacy of serum TSH suppression (0.293). The total risk score for each patient was calculated and three categories of remission probability were proposed: ${\leq}1.628$ points (low risk, 83% remission), 1.629-1.816 points (intermediate risk, 87% remission), and ${\geq}1.817$ points (high risk, 93% remission). The concordance (C-index) was 0.761 (95% CI 0.754-0.767). Conclusions: The clinical prognostic scoring model developed to quantify the probability of disease remission can serve as a useful tool in personalized decision making regarding treatment in differentiated thyroid cancer patients.

• 한국농공학회논문집
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• 제61권6호
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• pp.81-92
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• 2019

The objective of this study is to evaluate hydrologic impacts of climate change according to downscaling methods using the Soil and Water Assessment Tool (SWAT) model at watershed scale. We used the APCC Integrated Modeling Solution (AIMS) for assessing various General Circulation Models (GCMs) and downscaling methods. AIMS provides three downscaling methods: 1) BCSA (Bias-Correction & Stochastic Analogue), 2) Simple Quantile Mapping (SQM), 3) SDQDM (Spatial Disaggregation and Quantile Delta Mapping). To assess future hydrologic responses of climate change, we adopted three GCMs: CESM1-BGC for flood, MIROC-ESM for drought, and HadGEM2-AO for Korea Meteorological Administration (KMA) national standard scenario. Combined nine climate change scenarios were assessed by Expert Team on Climate Change Detection and Indices (ETCCDI). SWAT model was established at the Mankyung watershed and the applicability assessment was completed by performing calibration and validation from 2008 to 2017. Historical reproducibility results from BCSA, SQM, SDQDM of three GCMs show different patterns on annual precipitation, maximum temperature, and four selected ETCCDI. BCSA and SQM showed high historical reproducibility compared with the observed data, however SDQDM was underestimated, possibly due to the uncertainty of future climate data. Future hydrologic responses presented greater variability in SQM and relatively less variability in BCSA and SDQDM. This study implies that reasonable selection of GCMs and downscaling methods considering research objective is important and necessary to minimize uncertainty of climate change scenarios.

• Nuclear Engineering and Technology
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• 제42권4호
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• pp.339-364
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• 2010

Following a joint OECD/NEA-IAEA-sponsored meeting to define the current role and future perspectives of the application of Computational Fluid Dynamics (CFD) to nuclear reactor safety problems, three Writing Groups were created, under the auspices of the NEA working group WGAMA, to produce state-of-the-art reports on different aspects of the subject. The work of the second group, WG2, was to document the existing assessment databases for CFD simulation in the context of Nuclear Reactor Safety (NRS) analysis, to gain a measure of the degree of quality and trust in CFD as a numerical analysis tool, and to take initiatives to extend the existing databases. The group worked over the period of 2003-2007 and produced a final state-of-the-art report. The present paper summarises the material gathered during the study, illustrating the points with a few highlights. A total of 22 safety issues were identified for which the application of CFD was considered to potentially bring real benefits in terms of better understanding and increased safety. A list of the existing databases was drawn up and synthesised, both from the nuclear area and from other parallel, non-nuclear, industrial activities. The gaps in the technology base were also identified and discussed. In order to initiate new ways of bringing experimentalists and numerical analysts together, an international workshop -- CFD4NRS (the first in a series) -- was organised, a new blind benchmark activity was set up based on turbulent mixing in T-junctions, and a Wiki-type web portal was created to offer online access to the material put together by the group giving the reader the opportunity to update and extend the contents to keep the information source topical and dynamic.

• 한국토양비료학회지
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• 제44권6호
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• pp.983-990
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• 2011

Universal Soil Loss Equation (USLE) has been used to estimate potential long-term soil erosion in the fields. However, the USLE does not estimate sediment yield due to lack of module considering sediment delivery ratio (SDR) for watershed application. For that reason, the Sediment Assessment Tool for Effective Erosion Control (SATEEC) system was developed and applied to compute the sediment yield at watershed scale. However, the R factor of current SATEEC Ver. 2.1 was estimated based on 5-day antecedent rainfall, it is not related with fundamental concept of R factor. To compute R factor accurately, the energy of rainfall strikes should be considered. In this study, the R module in the SATEEC system was enhanced using formulas of Williams, Foster, Cooley, CREAMS which could consider the energy of rainfall strikes. The enhanced SATEEC system ver. 2.2 was applied to the Imha watershed and monthly sediment yield was estimated. As a result of this study, the $R^2$ and NSE values are 0.591 and 0.573 for calibration period, and 0.927 and 0.911 for validation period, respectively. The results demonstrate the enhanced SATEEC System estimates the sediment yield suitably, and it could be used to establish the detailed environmental policy standard using USLE input dataset at watershed scale.

• 임상간호연구
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• 제17권2호
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• pp.176-191
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• 2011

Purpose: This methodological study translated, adapted, and validated the evidence based guideline of RNAO (Registered Nurses Association of Ontario) in Canada, for acute stroke care to domestic circumstances. Methods: Quality of the RNAO guideline was evaluated using AGREE tool. Then the guideline was translated into Korean and a preliminary guideline was established After checking content validation by an expert group, the Korean version of the guideline was applied to clinical settings to see its applicability. Results: The RNAO guideline in Korea was deemed appropriate. The Korean version of the guideline was drawn up with 56 items in 3 areas in stroke system related nursing, nursing of acute stroke inpatients, and stroke nursing assessment. A questionnaire survey was performed on appropriateness, enforceability, and applicability of those recommendations. A total of 54 recommendations were finalized after deleting 2 items below CVI 0.7 and correcting 3 items by taking professional advices. After trial application of the guideline to 40 stroke patients hospitalized at a ward of a hospital in Seoul, its performance was improved but was not statistically significant. Conclusion: This guideline is expected to contribute to improving nursing quality by offering it as a guide to evidence based practices for acute stroke care in Korea.

• 대한간호학회지
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• 제51권5호
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• pp.617-629
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• 2021

Purpose: The aim of this study was to examine the validity and reliability of the Korean version of the self-efficacy for managing chronic disease 6-item scale (SECD-6-K). Methods: The English version of the Self-Efficacy for Managing Chronic Disease 6-item Scale first underwent forward and backward translation procedures. The SECD-6-K was then used to collect data from 350 adults diagnosed with chronic diseases. Content, construct, convergent, discriminant, and criterion validity were all evaluated. Reliability was assessed using Cronbach's α. SPSS 25.0 and the data were analyzed using AMOS 26.0 software. Results: The SECD-6-K consists of six items in two domains: disease management and health behavior. The results for construct, convergent, and discriminant validity were good. Exploratory factor analysis produced eigen values between 2.27 and 3.28, with factors total explained cumulative variance of 91.1%. Confirmatory factor analysis supported goodness of fit and reliability for the modified SECD-6-K model. The criterion validity also showed significant correlation with both the Patient Health Questionnaire and 12-item Short-Form Health Survey version 2. Finally, reliability was found to be excellent. Conclusion: This study identified the high reliability and validity of SECD-6-K. The SECD-6-K is an appropriate tool for determining Korean patients' self-efficacy in managing their chronic conditions. Therefore, this scale may be used in clinical settings as well as in educational and research settings.

• International Journal of Computer Science & Network Security
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• 제21권7호
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• pp.119-124
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• 2021

Today, both sides of modern culture are decisively invaded by digitalization. Authentication is considered to be one of the main components in keeping this process secure. Cyber criminals are working hard in penetrating through the existing network channels to encounter malicious attacks. When it comes to enterprises, the company's information is a major asset. Question here arises is how to protect the vital information. This takes into account various aspects of a society often termed as hyper connected society including online communication, purchases, regulation of access rights and many more. In this research paper, we will discuss about the concepts of MFA and KBA, i.e., Multi-Factor Authentication and Knowledge Based Authentication. The purpose of MFA and KBA its utilization for human.to.everything..interactions, offering easy to be used and secured validation mechanism while having access to the service. In the research, we will also explore the existing yet evolving factor providers (sensors) used for authenticating a user. This is an important tool to protect data from malicious insiders and outsiders. Access Management main goal is to provide authorized users the right to use a service also preventing access to illegal users. Multiple techniques can be implemented to ensure access management. In this paper, we will discuss various techniques to ensure access management suitable for enterprises, primarily focusing/restricting our discussion to multifactor authentication. We will also highlight the role of knowledge-based authentication in multi factor authentication and how it can make enterprises data more secure from Cyber Attack. Lastly, we will also discuss about the future of MFA and KBA.

• 한국지하수토양환경학회지:지하수토양환경
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• 제26권6호
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• pp.118-129
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• 2021

The sediment transportation caused by soil erosion due to rainfall-discharge in the large watershed scale plays critical role in human society. The relationship between rainfall-discharge-sediment transportation is depending on the start time of rainfall and end of rainfall but, the studies related with rainfall characteristics are insufficient. In this study, The Soil and Water Assession Tool (SWAT) model was used to study the relationship between rainfall-discharge-sediment transportation at the Sook river watershed which is monitored by the Ministry of Environment. To do this, first of all, the sensitivity analysis about model attributes was performed using monitored data. The accuracy analysis of SWAT model was conducted using the model's efficiency index (Nash and Sutcliffe model efficiency; NSE) and the coefficient of determination (R²). After that, it was studied what results could be obtained according to changes in rainfall timing and end points. In the result of discharge simulation, the modified rainfall values (sum of total rainfall starting time and end time) showed more high accuracy values (R²:0.90, NSE: 0.8) than original rainfall values (R²:0.76, NSE: 0.72). In the result of sediment transportation simulation, during calibration had more resonable results(R²:0.87, NSE: 0.86) than compared with original rainfall values (R²:0.44, NSE: 0.41). However, validation results of sediment transportation simulation showed low accuracy values compared with calibration results. This results maybe cause monitoring periods of sediment flow compared with discharge monitoring periods. Nevertheless, since rainfall characteristic plays critical rule in model results, continuous research on rainfall characteristic is needed.

• 한국시뮬레이션학회논문지
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• 제28권2호
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• pp.149-158
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• 2019

본 연구에서는 전장이나 재난 환경과 같은 인간이 투입되기 힘든 환경에서 인간을 대신하여 부상자 구조 및 위험물 처리 목적으로 개발된 구조로봇의 효율적 개발을 위한 통합 M&S 프레임워크를 소개한다. 개발된 통합 M&S 프레임워크는 계층화, 모듈화된 통합운동제어 소프트웨어의 구조에 기인하여 통합운동제어 소프트웨어 구조는 동일하게 이용하며 로봇 플랫폼을 시뮬레이션 프로그램으로 대체하여 SILS(Software-in-the-Loop Simulation) 개념의 M&S를 가능하게 하였다. 이를 활용하여 로봇 설계 및 로봇 제어 기술의 성능 검증 등의 개발 전 과정을 효율적으로 수행하였고, 비정형 환경에서의 원격 운용성 향상도 가져왔다. 통합 M&S 프레임워크의 적극적인 활용을 통해 구조로봇의 성공적인 개발 및 성능 확인을 완료하였으며, 구조로봇의 주요 기술 중 하나인 가변형상 제어를 통한 주행 안정화 기술 개발 과정에 적용된 통합 M&S 프레임워크의 사례를 통해 효용성을 확인한다.

• 한국기계가공학회지
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• 제18권6호
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• pp.91-97
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• 2019

Rotating machining unit is a revolutionary product that can process worm shaft or spiral shaft with fast and precise, a rotary type cutting tool, which is attached to automatic lathe and processes spiral groove on outer circumference of round bar. In this work, a study on micro tooth shape modification method of driving gear train in the rotating machining unit was presented. To observe the effect on power transmission characteristics of the driving gear pair, visualize the gear meshing condition and the load distribution on the gear teeth by using the professional gear train analysis program RomaxDesigner. By comparing the repeated analysis results, the effect of micro tooth shape modification on power transmission characteristics on driving gear can be summarized. The optimized gears were fabricated and measured by precision tester as a validation in this research.