• 제목/요약/키워드: Vain

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간암 치료 신약 개발 및 이의 제제화 연구 (II. 제제화 연구)

  • 정홍석;최명준;장진수;황유경;안교한;이석종
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 1994년도 춘계학술대회 and 제3회 신약개발 연구발표회
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    • pp.251-251
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    • 1994
  • 1차년도에서 이미 확립한 다양한리포좀의 제조 방법에 따라간세포를표 적하기 위해 이들 리포좀의 조성에 galactocercbroside를 함유시켜 targeted liposomes을 제조하였다. 표적리포좀의 제조 방법에 따른 봉합율 (cncapsulation)과 안정성을 조사했을 때, freezing-thawing 과정을 거친 리포좀이 encapsulation 과 stability가 가장 뛰어남을 알 수 있었다. In vitro 간세포 표적능력을 in vitro cell culture system에서 간세포 cell line (Hep G2, 2.2.15과 다른 cell line (Vero E6, J82)에 대한 표적리포좀과 control liposomes의 uptake를 FTTC 또는 CF 형광으로 측정했을 때, 표적리포좀이 간세포 cell line에 더 많이 uptake하는 것을 알았다. In vivo 실험에서는 6 - 8 주령의 mouse tail vain에 표적리포좀과 control liposomes을 주사하여 각 장기에 존재하는 리포좀의 양을 형광으로 측정했을 때, 표적리포좀 (targetcd liposomes)이 다른 장기에 비해 liver에 선택적으로 많이 분포함을 알수있었다. 또한 간암의 효과적인 치료를 위해 간세포와 암세포를 동시에 표적할 수는 double targeting liposomes을 design 하였다.

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Dactylospora glaucomarioides (Ascomycetes, Dactylosporaceae): A Lichenicolous Fungus New to South Korea

  • Joshi, Yogesh;Knudsen, Kerry;Wang, Xin Yu;Hur, Jae-Seoun
    • Mycobiology
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    • 제38권4호
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    • pp.321-322
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    • 2010
  • The lichenicolous fungi flora of South Korea is poorly known. During recent field trips to various parts of South Korea and after an extensive examination of herbarium lichen specimens, we encountered a lichenicolous fungi growing over a thallus of the lichen Ochrolechia yasudae Vain., characterized by small black apothecia with mostly three-septate brown ascospores. It was identified as Dactylospora glaucomarioides. This is the first report of this lichenicolous fungus from South Korea. A taxonomic description and comments are presented.

Monotonic and Parallelizable Algorithm for Simultaneous Reconstruction of Activity/Attenuation using Emission data in PET

  • Kim, Seung-Gu
    • Communications for Statistical Applications and Methods
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    • 제8권1호
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    • pp.299-309
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    • 2001
  • In PET(Positron Emission Tomography), it is necessary to use transmission scan data in order to estimate the attenuation map. Recently, there are several empirical studies in which one might be able to estimate attenuation map and activity distribution simultaneously with emissive sinogram alone without transmission scan. However, their algorithms are based on the model in which does not include the background counts term, and so is unrealistic. If the background counts component has been included in the model, their algorithm would introduce non-monotonic reconstruction algorithm which results in vain in practice. in this paper, we develop a monotonic and parallelizable algorithm for simultaneous reconstruction of both characteristics and present the validity through some simulations.

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대학생의 허영심 유형에 따른 가격태도와 소매점 선택에 관한 연구 (Price Attitude of Apparel Products and Store Choice Behavior According to Vanity Type of College Students)

  • 남미우
    • 대한가정학회지
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    • 제48권2호
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    • pp.23-38
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    • 2010
  • The objectives of this study were 1) to classify survey respondents according to vanity scales, and 2) to identify price attitude among the classified groups. The participants were 276 university students who were residents in Seoul. Data were analyzed by factor analysis, cluster analysis, and one-way ANOVA. The vanity scales consisted of four factors; physical concern, physical view, achievement concern and achievement view. Based on these four factors, the respondents were classified into three clusters(interested, vain, and self-confident) as an attached group name. There were significant differences in the dimensions of materialism, price attitude and store choice behavior among the clusters. Marketing implications are discussed.

New Species and New Record of Genus Chrysothrix (Chrysotrichaceae, Arthoniales) from South Korea and Chile

  • Liu, Dong;Oh, Soon-Ok;Park, Jung-Shin;Hur, Jae-Seoun
    • Mycobiology
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    • 제46권3호
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    • pp.185-191
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    • 2018
  • The genus Chrysothrix is very common around the world and easy to be recognized by its bright yellowish granular thallus. In this study, investigations of lichen mycota in South Korea and Chile from 2010 to 2017 have been done, and some Chrysothrix specimens were collected, based on the morphological and chemical study on these specimens, five species were confirmed in this study, including one new species from Chile, Chrysothrix chilensis D. Liu & J.-S Hur, and one new record from South Korea, C. xanthina (Vain.) Kalb. Meanwhile, detail description and illustration for each species were present in this study.

The Lichen Genus Sticta in South Korea

  • Jayalal, Udeni;Joshi, Santosh;Oh, Soon-Ok;Kim, Jung A;Koh, Young Jin;Crisan, Florin;Hur, Jae-Seoun
    • Mycobiology
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    • 제42권1호
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    • pp.6-11
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    • 2014
  • Sticta (Schreber.) Ach. is one of the common lichen genera in tropical and subtropical regions, but not in the Korean Peninsula. For almost two decades, no detailed taxonomic or revisionary study has been done on this genus. This study was based on the specimens deposited in the lichen herbarium at the Korean Lichen Research Institute, and the samples were identified on the basis of recent literature. In this revisionary study, a total of eight species of Sticta, including a newly recorded one are documented. These species include Sticta fuliginosa (Dicks.) Ach., Sticta gracilis (M$\ddot{u}$ll. Arg.) Zahlbr., Sticta limbata (Sm.) Ach., Sticta nylanderiana Zahlbr., Sticta sublimbata (J. Steiner) Swinscow & Krog, Sticta weigelii (Ach.) Vain., Sticta wrightii Tuck., and Sticta yatabeana M$\ddot{u}$ll. Arg. Detailed descriptions of S. nylanderiana, S. sublimbata, S. weigelii, and S. yatabeana with their morphological, anatomical, and chemical characteristics are provided. A key description of all known Sticta species of the Korean Peninsula is also presented.

외판원문제(TSP)를 위한 실용적인 근사해법 (A Practical Approximation Method for TSP)

  • 백관호
    • 한국경영과학회:학술대회논문집
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    • 한국경영과학회/대한산업공학회 2005년도 춘계공동학술대회 발표논문
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    • pp.768-772
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    • 2005
  • 외판원문제(TSP)는 아직까지도 쉽게 풀리지 않는 NP-complete군에 속하는 어려운 문제이다. TSP의 결정적인 난점은 {0,1}의 정수해를 보장하면서 동시에 부분순환(sub-tour)을 피해야 한다는 점이다. 우리는 TSP를 두 단계로 나누어 탐색한다. 첫째, 초기해는 2개의 마디로 이루어진 최소단위의 부분순환에 가장 적은 비용의 마디를 하나씩 추가적으로 더하여 모든 마디가 포함될 때까지 반복하여 만든다. 둘째, 선택된 초기해의 마디를 임의의 단위로 잘라내어 그 개선비용이 음수인 경우 다른 마디 자리에 삽입함으로서 새로운 전체순환(grand tour)을 만들어 해를 개선한다. 우리는 최적해가 알려진 TSPLIB에 적용하여 그 결과를 비교하고 또한 랜덤하게 생성된 마디 200개까지의 TSP문제에 대하여 실험을 하였다. 대부분의 해는 최적해로부터 1% 이내의 결과로서 30분 이내에 얻을 수 있었다. 우리의 방법은 실용적인 문제에 적용할 수 있을 것으로 판단된다.

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상대정맥내 폴리에틸렌관 잔존물 치험 1례 (A Retained Polyethylene Catheter Fragment in Superior Vena Cava - A case report-)

  • 김주현
    • Journal of Chest Surgery
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    • 제13권2호
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    • pp.134-137
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    • 1980
  • This represents a case report of the retained polyethylene catheter fragment in superior vena cava. A 39 year old male was admitted to this Korea University Hospital a short time after compression wound on abdomen with heavy cement material in emergency room, a polyethylene catheter was introduced into the right subclavian vein through a needle. But when the polyethylene catheter was attempted to withdraw the catheter was severed by the beveled tip of the needle. Later that day, chest X-ray disclosed the presence of the fragment extending from right subclavian vein to the superior vena cava. {Fig. 1 and Fig. 2]. Local exploration by way of an infraclavicular incision was unsuccessful in locating the catheter fragment. Another attempt was then made remove the catheter by means a biotome, which is originally a device for the biopsy of the myocardium, introduced through the right great saphenous vein. This procedure, though well tolerated by the patient, was in vain. After 11 days later, during that time he was taken a laparotomy with drain, another operation for removal of retained catheter fragment was performed through median sternotomy. After exposure of the right subclavian vein, innominate vein, and superior vena cava, an incision 1 cm in |length was made directly over the palpated catheter. The catheter immediately was picked upward and removed. The length of the catheter was approximately 8 cm. [Fig 3 ] There was no evidence of thromboembolism from the catheter or other complications. The patient made an uneventful recovery, and was discharged asymptomatic on the 9th postoperative day.

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근대 이상주거 고댕의 사회궁전에 나타나는 건축특성 연구 (A Study on the Architectural Characteristics of Godin's Social Palace System of Modern Ideal Housing)

  • 백승관
    • 한국주거학회논문집
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    • 제25권1호
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    • pp.1-13
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    • 2014
  • This study analyzes the architectural characteristics of Godin's Social Palace system of ideal housing for laborers during the 19th century. Utopian socialists in the first half of the 19th century proposed different solutions to reform their chaotic capitalist society, in response to the maladies of the Industrial Revolution. Fourier designed an ideal housing referred to as the Phalanstere, in which residences coexisted in a cooperative society. His disciples tried in vain to make this ideal housing system real. The only realization of this type of ideal housing was called Godin's Social Palace, which was constructed in Guise, France. The main architectural characteristics of Godin's Social Palace are as follows: dwelling units in consideration of function and expansion are applied basically in the housing. Further, a natural ventilation system is applied between housing and courtyard, and water supply is established in the housing. In Particular, natural lighting and artificial illumination are used in the entire building appropriately. In addition, a device which promotes a community between inhabitants is established. As for such modern facilities and social devices, inhabitants were able to live a more comfortable life. Hence, it is confirmed to have been one of the important factors for sustaining the Social Palace for more than 100 years.

항공운송인의 책임제한의 철폐 (The Collapse of Warsaw Liability Limitation)

  • 오수근
    • 항공우주정책ㆍ법학회지
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    • 제9권
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    • pp.277-298
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    • 1997
  • Air transportation industry was established on a basis of liability limitation from the outset. Many treaties, however, had to be drafted since 1960' s to meet the need of the Unites States, who argued full compensation without limitation like other torts cases, but most of them were in vain. The Japanese Initiative in 1992, though being aimed to lower a level of compensation in air crash cases to that of other transportation accidents, showed a way to the U.S. how to solve the issue. Instead of obtaining an multilateral agreement through ICAO, the U.S. persuaded IATA to organize intercarrier consensus for voluntary waive the limitation. IATA succeeded in adopting Intercarrier Liability Agreement in 1995, in which carriers agreed not to use Warsaw limitation and accepted strict liability up to 100,000SDRs. Through a series of negotiation to implement the Intercarrier agreement, US DOT tried to insert a domicile standard provision to the agreement which enable US victims to be compensated according to the law of the U.S. regardless of the situation. IATA opposed the intent aggressively. The U.S. set back to the starting point remaining issues for further discussion. The liability limitation under the Warsaw system is being collapsed. It is the result of a simple logic; liability limitation cannot be maintained without appropriate compensation.

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