• 제목/요약/키워드: VC-1

검색결과 362건 처리시간 0.021초

신뢰성지수를 이용한 효율적인 발파설계 (An Efficient Blast Design using Reliability Index)

  • 박연수;박선준;강성후
    • 소음진동
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    • 제8권5호
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    • pp.821-831
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    • 1998
  • The actual ground vibrations due to NATM and foundation blasting at Seoul(weathered rock), Pusan(weathered rock) and Youngkwang(quartz andesite) have been measured, and the data were analyzed using reliability index($\beta$) to determinate the vibration equations and the maximum charge weight for efficient blast. These were suggested with the division of ultimate limit state($\beta$=0), serviceability limit state($\beta$=1.28) and safety state($\beta$=3), respectively. The reliability index 0 mean 50% data line obtained by the least squares best-fit line. The reliability index 1.28 and 3 represent bounds below 90% and 99.9% of the data, respectively. In this study, reliability index $\beta$=1.28 with security and economy was suggested. The maximum charge weight equations for efficient blast were obtained in W=(Vc/384.90)1.5151.D3(Seoul), W=(Vc/579.82)1.4706.D3(Pusan). W=(Vc/1654.01)1.3456.D3(Youngkwang), and the blast vibration equatiions in V=385(SD)-1.98(Seoul), V=580(SD)-2.04(Pusan), V=1654(SD)-2.23(Youngkwang), respectively. From this study, inference and analysis methods of vibration equations using reliability theory were established.

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Effects of Feedback Respiratory Exercise and Diaphragm Respiratory Exercise on the Pulmonary Functions of Chronic Stroke Patients

  • Seo, Kyo Chul;Kim, Hyeon Ae;Lim, Sang Wan
    • 국제물리치료학회지
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    • 제3권2호
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    • pp.458-463
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    • 2012
  • This study is to examine the effects of a feedback breathing device exercise and diaphragm breathing exercise on pulmonary functions of chronic strokes patients. The selection of 20 subjects was divided equally and placed into a experiment group and a control group and the intervention was applied four times per a week for five weeks. In each session, both groups received rehabilitative exercise treatment for 30 minutes, and a feedback breathing device exercise for 15 minutes. In addition, experimental group conducted a combination of diaphragm breathing exercise for 15 minutes. Prior to and after the experiment, patients' pulmonary functions were measured using a spirometer. The pulmonary function tests included FVC, FEV1, FEV1/FVC, PEF, VC, TV, IC, ERV, IRV. With respect to changes in the pulmonary functions of both groups, the experimental group significantly differed in FVC, FEV1, TV, ERV but did not in PEF, FEV1/FVC, VC, IRV. The control group did not significantly differ in any of the tests. There were significant differences in FEV1, FEV1/FVC, TV, ERV between the two groups, but no significant differences in FVC, PEF, FEV1/FVC, VC, IRV between them after the experiment. The experimental group, which conducted a combination of a feedback breathing device exercise and diaphragm breathing exercise, saw their respiratory ability increase more significantly than the control group. The breathing exercise was found to improve pulmonary function in chronic stroke patients.

항암제에 내성인 생쥐의 백혈병세포 L1210의 세포막 단백질의 변환 (Membrane Protein Alterations Associated with Anticancer Drug Resistance in Mouse Lymphoblastic Leukemia L1210 Cells)

  • 김성용;손성권;김재룡;김정희
    • Journal of Yeungnam Medical Science
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    • 제10권2호
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    • pp.432-444
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    • 1993
  • Adriamycin과 vincristine 각각에 내성인 생쥐의 림프아세포성 백혈병세포 L1210세포의 특성과 내성관계 단백질을 찾아내고 항암제의 세포내 분포를 관찰하였다. 항암제의 내성생성은 adriamycin이 $10^{-5}M$$10^{-6}M$에서 자란 세포를 L1210-$AdR_5$$-AdR_6$로 하고 vincristine은 $10^{-6}M$$10^{-7}M$에서 자란 세포를 L1210-$VcR_6$$-VcR_7$로 하였다. 감수성세포는 L1210으로 하였다. 내성세포의 성장속도는 감수성세포에 비해 느렸으며 doubling time은 L1210가 29.7시간, L1210-$AdR_5$가 68.7시간 $-VdR_6$가 58.2시간이었다. 복합내성은 내성인자로 표기되었고 L1210-$AdR_5$는 vincristine에 대해 76.4배, $-VcR_6$는 adriamycin에 대해 98.6배로 나타냈다. 감수성세포와 내성세포의 세포막 단백질을 비교한 결과 L1210-$AdR_5$에서는 220, 158, 88 Kd의 내성관계단백질이 나타났고 $-VcR_6$에서는 158, 140 및 88Kd의 내성관계단백질이 관찰되었다. 세포막 표면단백질을 $^{125}I$로 결합시켜 자가방사선상으로 분석하였다. 세포막 표면단백질에 결합되는 $^{125}I$의 정도는 L1210에 0.95% L1210-$AdR_5$에 5.4%, $-VcR_6$에 1.7%였다. 세포막표면단백질은 L1210-$AdR_5$에서는 158, 72.8 및 42.4 Kd의 단백질, $-VcR_6$에서는 300, 158, 72.8 및 42.4 Kd의 단백질이 관찰되었다.

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Tomato spotted wilt virus를 위한 간편한 식물바이러스 핵산진단법: Virion Captured/RT-PCR (VC/RT-PCR) (Convenient Nucleic Acid Detection for Tomato spotted wilt virus: Virion Captured/RT-PCR (VC/RT-PCR))

  • 조점덕;김정수;김현란;정봉남;류기현
    • 식물병연구
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    • 제12권2호
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    • pp.139-143
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    • 2006
  • VC/RT-PCR은 바이러스의 단백질과 PCR 튜브의 재질적 특성을 이용하여 바이러스 이병주의 즙액으로부터 핵산을 지니고 있는 바이러스를 polypropylene에 부착시키고 그 외 PCR 활성을 저해하는 식물 즙액은 PBST로 제거해 주므로써 정확하고 깨끗한 바이러스 진단이 가능하다. 이 방법은 바이러스에 대한 항혈청이 전혀 필요 없으며 포장 시료를 직접 이용해 30 분 이내에 바이러스 핵산을 획득할 수 있어 바이러스 진단이 빠르고 간편하며 경제적이고 감도 높은 실용적인 방법이다. TSWV 에 대한 VC/RT-PCR을 위해 다양한 마쇄 완충액을 시험한 결과 0.5%의 Sodium sulphite를 포함한 0.01M Potassium phosphate (pH 7.0)가 가장 안정적이었으며 VC/RT-PCR을 이용하여 TSWV에 대한 최적의 처리 과정을 확립하였다. TSWV에 최적인 완충액에 마쇄한 바이러스 감염 잎의 조즙액을 이용한 한계 희석 농도는 $10^{-5}$으로 높은 감도를 보여 낮은 농도의 바이러스를 보유한 기주로부터 정확하 게 바이러스를 감지해 낼 수 있게 되었다. 두가지 이상의 바이러스에 감염된 기주로부터 두 가지 이상의 프라이머를 이용해 바이러스를 감지해 내는 다중 진단을 위한 실험 중 식물체의 종류와 바이러스의 Primer의 종류가 진단결과의 정확도에 큰 영향을 미치며 이러한 결과는 식물체 즙액을 바로 이용하는 VC/RT-PCR 방법은 물론 식물체로부터 Total RNA를 따로 분리하여 RT-PCR을 이용한 결과에서도 동일하게 나타났다. 따라서 편리하고 실용 적인 VC/RT-PCR법의 정확성을 최대화시키기 위해서는 다중 진단을 저해하는 식물체적 원인과 Primer 사이의 간섭 현상에 대한 연구가 더 진행될 것이며 이러한 원인을 충분히 제거해 줄 수 있는 마쇄 완충액을 개발하고 프라이머 제작을 더욱 신중히 해야 할 것이다.

L1210 암세포에서 Multidrug Resistance-associated Protein (MRP), c-myc 및 c-fos 유전자의 발현양상 (Expression of Multidrug Resistance-associated Protein (MRP), c-myc and c-fos in L1210 Cells)

  • 김성용
    • Journal of Yeungnam Medical Science
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    • 제14권1호
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    • pp.67-76
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    • 1997
  • 항암제에 대한 내성은 내인성 또는 획득한 내성 모두가 암의 치료에 장애가 된다. P-당단백질을 encode하고있는 mdr1 유전자의 발현이 항암제에 대해 내성을 가지고 있는 암세포에서 많이 관찰되고 있으며, 최근에는 시험관적으로 항암제에 대한 내성이 유도된 암세포주들에서 mdr1 유전자가 발현되지 않는 암세포들이 보고되고 있다. 다제내성에 관계하는 또 하나의 유전자인 MRP 발현정도를 L1210세포와 내성인 L1210변이주들에서 조사하였으며, c-myc과 c-fos 유전자의 발현변화를 관찰하였다. RT-PCR을 시행하여 L1210, L1210AdR, L1210VcR에서 MRP 유전자발현을 확인하였으며, Northern hybridization한 결과 L1210세포에 비하여 L1210AdR은 유전자 발현이 40% 정도 감소하였으며, L12l0Cis는 90% 정도의 유전자 발현감소가 관찰되었다. c-myc과 c-fos유전자의 Northern hybridization한 결과 L1210에 비하여 L1210AdR은 발현감소가 나타났으나, L1210VcR과 L1210Cis의 경우는 오히려 발현증가가 관찰되었다.

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Phonetic Functionalism in Coronal/Non-coronal Asymmetry

  • Kim, Sung-A.
    • 음성과학
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    • 제10권1호
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    • pp.41-58
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    • 2003
  • Coronal/non-coronal asymmetry refers to the typological trend wherein coronals rather than non-coronals are more likely targets in place assimilation. Although the phenomenon has been accounted for by resorting to the notion of unmarkedness in formalistic approaches to sound patterns, the examination of rules and representations cannot answer why there should be such a process in the first place. Furthermore, the motivation of coronal/non-coronal asymmetry has remained controversial to date even in the field of phonetics. The present study investigated the listeners' perception of coronal and non-coronal stops in the context of $VC_{1}C_{2}V$ after critically reviewing the three types of phonetic accounts for coronal/non-coronal asymmetry, i.e., articulatory, perceptual, and gestural overlap accounts. An experiment was conducted to test whether the phenomenon in question may occur, given the listeners' lack of perceptual ability to identify weaker place cues in VC transitions as argued by Ohala (1990), i.e., coronals have weak place cues that cause listeners' misperception. 5pliced nonsense $VC_{1}C_{2}V$ utterances were given to 20 native speakers of English and Korean. Data analysis showed that majority of the subjects reported $C_{2}\;as\;C_{1}$. More importantly, the place of articulation of C1 did not affect the listeners' identification. Compared to non-coronals, coronals did not show a significantly lower rate of correct identifications. This study challenges the view that coronal/non-coronal asymmetry is attributable to the weak place cues of coronals, providing evidence that CV cues are more perceptually salient than VC cues. While perceptual saliency account may explain the frequent occurrence of regressive assimilation across languages, it cannot be extended to coronal/non-coronal asymmetry.

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pVC, a Small Cryptic Plasmid from the Environmental Isolate of Vibrio cholerae MP-1

  • Zhang, Ruifu;Wang, Yanling;Leung, Pak Chow;Gu, Ji-Dong
    • Journal of Microbiology
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    • 제45권3호
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    • pp.193-198
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    • 2007
  • A marine bacterium was isolated from Mai Po Nature Reserve of Hong Kong and identified as Vibrio cholerae MP-1. It contains a small plasmid designated as pVC of 3.8 kb. Four open reading frames (ORFs) are identified on the plasmid, but none of them shows homology to any known protein. Database search indicated that a 440 bp fragment is 96% identical to a fragment found in a small plasmid of another V. cholerae. Further experiments demonstrated that a 2.3 kb EcoRI fragment containing the complete ORF1, partial ORF4 and their intergenic region could self-replicate. Additional analyses revealed that sequence upstream of ORF1 showed the features characteristic of theta type replicons. Protein encoded by ORF1 has two characteristic motifs existed in most replication initiator proteins (Rep): the leucine zipper (LZ) motif located at the N-terminal region and the alpha helix-turn-alpha helix motif (HTH) located at the C-terminal end. The results suggest that pVC replicates via the theta type mechanism and is likely a novel type of theta replicon.

전기자동차의 유럽 측면 충돌 특성 기초 연구(II) (A Basic Study of the European Side Impact Characteristics of Electric Vehicle(II))

  • 조용범;신효철
    • 한국자동차공학회논문집
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    • 제10권1호
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    • pp.143-152
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    • 2002
  • European side impact analysis of an electric vehicle was done using the robust design method. In order to minimize VC as well as rib deflection, the injury response table which consists of rib deflection and VC response table has been introduced. The sensitivities and interactions are almost the same when it was compared with those of rib deflection and VC response table. Using internal energy of the factors, the starting time of dummy rib deflection and the contact average velocity, the internal energy and time-velocity response table were introduced. It is shown that the results of the new response tables have the similar characteristics to those of the Injury response table. It is suggested that the internal energy and time-velocity response table should be utilized to minimize injuries.

JCT-VC의 HVC 표준화 동향 (Standardization Trends of High-performance Video Coding of Joint Collaborative Team on Video Coding)

  • 정세윤;김휘용;임성창;김종호;이하현;이진호;최해철;조숙희;최진수
    • 전자통신동향분석
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    • 제25권2호
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    • pp.8-18
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    • 2010
  • AVC|H.264 보다 2배 이상의 압축률을 목표로 하는 HVC 표준화가 2010 년1월부터 MPEG과 VCEG이 공동 설립한 JCT-VC에 의해 시작되었다. AVC|H.264가 유선망과 무선망이 통합되고 방송과 통신이 융합되어 언제 어디서나 인터넷과 방송을 즐길 수 있는 방통 융합서비스 시대를 개척하였다면, HVC는 방통융합 서비스를 한 단계 더 진보시킬 수 있는 표준이 될 것으로 예상된다. 본 고에서는 MPEG과 VCEG 이 공동으로 추진하는 JCT-VC HVC 표준화의 동향에 대해서 설명한다.

Pyrochlore상의 부피분율에 따른 PMN-Pyrochlore 2상 혼합체의 유전율변화;General Effective Media식의 적용 (Variation of Dielectric Constant with the Volume Fraction of Pyrochlore Phae in the PMN-Polychlore Diphasic System ; Application of General Effective Media Equation)

  • 허강일;김정주;김남경;김진호;조상희
    • 한국세라믹학회지
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    • 제30권1호
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    • pp.78-84
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    • 1993
  • In PMN-pyrochlore phase mixtures, dielectric constant was measured as a function of the volume fraction of pyrochlore phase and considered with general effective media(GEM) equation. For the application of GEM equation to this system, the critical volume fraction(Vc) where connectivity between the perovskite PMN and pyrochlore phase changed from 0-3 to 3-3, was determined based on the each particle size ratio of two phases with microstructural observation. And then the t value was determined from modified percolation powder-law dependence ( K-Kc (V-Vc)t). In the case of applying such values of t and Vc to the GEM equation, which provided a reasonable fit to the measured dielectric constant within the experimental error range.

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