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Studies on N-Nitrosamine of Korean Ordinary Soysauce (한국 재래식 간장의 니트로소화합물에 관한 연구)

  • Sung, Nak-Ju;Hwang, Oe-Ja;Lee, Eung-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.17 no.2
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    • pp.125-135
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    • 1988
  • In recent years, the presence of N-nitrosamine, which was produced by the interaction of nitrite and secondary amine, in the fermented foods has been the subject of considerable interest and controversy. In this experiment, the levels of N-nitrosamine such as N-nitrosodimethylamine(NDMA), N-nitrosodiethylamine(NDEA) and N-nitrosodipropylamine(NDPA) in the Korean ordinary soysauce, which were added with ascorbic acid, sorbic acid, and sodium benzoate in the making of it were analyzed by low resolution mass spectrometry, and then the changes of dimethylamine(DMA), nitrate and nitrite nitrogen during the fermentation of it were observed. The contents of DMA nitrogen increased during the fermentation of Korean ordinary soysauce, continuously, but those of DMA nitrogen in the soysauce which had been added with ascorbic acid were inhibited, considerably, until the fermentation of 70days. The levels of nitrate nitrogen during the fermentation of Korean ordinary soysauee decreased, while those of nitrite nitrogen increased. The soysauce which had been incoporated with ascorbic acid in the making of it showed low amounts of nitrite. The concentration of NDMA in the control sample were 2.7 and $8.5{\mu}g/kg$ after the fermentation of 30 and 60 days, respectively, those of NDMA increased during the fermentation of Korean ordinary soysauce, but NDEA and NDPA in all of the soysauce were not detected. The samples were treated with ascorbic acid, sorbic acid, and sodium benzoate in the making of Korean ordinary soysauce were turn out to be effective in preventing the formation of NDMA. Inhibitive actions from food additives as above were, respectively, $82.2{\sim}87.0%$(ascorbic acid), $25.9{\sim}65.4%$(sorbic acid) an $13.2{\sim}63.5%$ (sodium benzoate) in comparison with control sample during the fermentation of Korean ordinary soysauce. NDMA contents were detected below $1.5{\mu}g/kg$ in the soysauce, which food additives were mixed to the pure NaCI in the brewing of it. Free amino acids such as glutamic acid, proline, and histidine were proved to be inhibiting the formation of NDMA during the fermentation of Korean ordinary soysauce. This might be due to the reaction above amino acids and nitrite by Van Slyke reaction.

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A PLS Path Modeling Approach on the Cause-and-Effect Relationships among BSC Critical Success Factors for IT Organizations (PLS 경로모형을 이용한 IT 조직의 BSC 성공요인간의 인과관계 분석)

  • Lee, Jung-Hoon;Shin, Taek-Soo;Lim, Jong-Ho
    • Asia pacific journal of information systems
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    • v.17 no.4
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    • pp.207-228
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    • 2007
  • Measuring Information Technology(IT) organizations' activities have been limited to mainly measure financial indicators for a long time. However, according to the multifarious functions of Information System, a number of researches have been done for the new trends on measurement methodologies that come with financial measurement as well as new measurement methods. Especially, the researches on IT Balanced Scorecard(BSC), concept from BSC measuring IT activities have been done as well in recent years. BSC provides more advantages than only integration of non-financial measures in a performance measurement system. The core of BSC rests on the cause-and-effect relationships between measures to allow prediction of value chain performance measures to allow prediction of value chain performance measures, communication, and realization of the corporate strategy and incentive controlled actions. More recently, BSC proponents have focused on the need to tie measures together into a causal chain of performance, and to test the validity of these hypothesized effects to guide the development of strategy. Kaplan and Norton[2001] argue that one of the primary benefits of the balanced scorecard is its use in gauging the success of strategy. Norreklit[2000] insist that the cause-and-effect chain is central to the balanced scorecard. The cause-and-effect chain is also central to the IT BSC. However, prior researches on relationship between information system and enterprise strategies as well as connection between various IT performance measurement indicators are not so much studied. Ittner et al.[2003] report that 77% of all surveyed companies with an implemented BSC place no or only little interest on soundly modeled cause-and-effect relationships despite of the importance of cause-and-effect chains as an integral part of BSC. This shortcoming can be explained with one theoretical and one practical reason[Blumenberg and Hinz, 2006]. From a theoretical point of view, causalities within the BSC method and their application are only vaguely described by Kaplan and Norton. From a practical consideration, modeling corporate causalities is a complex task due to tedious data acquisition and following reliability maintenance. However, cause-and effect relationships are an essential part of BSCs because they differentiate performance measurement systems like BSCs from simple key performance indicator(KPI) lists. KPI lists present an ad-hoc collection of measures to managers but do not allow for a comprehensive view on corporate performance. Instead, performance measurement system like BSCs tries to model the relationships of the underlying value chain in cause-and-effect relationships. Therefore, to overcome the deficiencies of causal modeling in IT BSC, sound and robust causal modeling approaches are required in theory as well as in practice for offering a solution. The propose of this study is to suggest critical success factors(CSFs) and KPIs for measuring performance for IT organizations and empirically validate the casual relationships between those CSFs. For this purpose, we define four perspectives of BSC for IT organizations according to Van Grembergen's study[2000] as follows. The Future Orientation perspective represents the human and technology resources needed by IT to deliver its services. The Operational Excellence perspective represents the IT processes employed to develop and deliver the applications. The User Orientation perspective represents the user evaluation of IT. The Business Contribution perspective captures the business value of the IT investments. Each of these perspectives has to be translated into corresponding metrics and measures that assess the current situations. This study suggests 12 CSFs for IT BSC based on the previous IT BSC's studies and COBIT 4.1. These CSFs consist of 51 KPIs. We defines the cause-and-effect relationships among BSC CSFs for IT Organizations as follows. The Future Orientation perspective will have positive effects on the Operational Excellence perspective. Then the Operational Excellence perspective will have positive effects on the User Orientation perspective. Finally, the User Orientation perspective will have positive effects on the Business Contribution perspective. This research tests the validity of these hypothesized casual effects and the sub-hypothesized causal relationships. For the purpose, we used the Partial Least Squares approach to Structural Equation Modeling(or PLS Path Modeling) for analyzing multiple IT BSC CSFs. The PLS path modeling has special abilities that make it more appropriate than other techniques, such as multiple regression and LISREL, when analyzing small sample sizes. Recently the use of PLS path modeling has been gaining interests and use among IS researchers in recent years because of its ability to model latent constructs under conditions of nonormality and with small to medium sample sizes(Chin et al., 2003). The empirical results of our study using PLS path modeling show that the casual effects in IT BSC significantly exist partially in our hypotheses.

쌍끌이 중층트롤어법의 연구 ( 1 ) - 모형어구의 망구형상에 관하여 - ( A Study on the Pair Midwater Trawling ( 1 ) - Mouth Performance of the Model Net - )

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    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.31 no.1
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    • pp.29-44
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    • 1995
  • A model experiment on the pair midwater trawl net applicable to 800 PS class Korean pair bottom trawlers was carried out in the special-prepared experimental thank. the tank was prepared as a reverse trapezoid shape in its vertical section by digging out flat soil. The dimension of the tank showed the 9.6 W$\times$43.0 L(m) of the upper fringe and the 4.8 W$\times$38.0 L(m) of the bottom with 3.0m in depth. The depth of water was maintained 2.7m during experiment. The model net was prepared based on the Tauti's similarity law of fishing gear in 1/30 scale considering the dimension of the experimental tank. Mouth performance of the model net during towing were determined by the photographs taken in front of the net mouth with the combinations of towing velocity, warp length and distance between paired boats. The results obtained can be summarized as follows: 1. Vertical opening of the model nets A and B was varied in the range of 0.18~0.88 m and 0.21~0.78 m (which can be converted into 5.4~26.4m and 6.3~23.4 m in the full-scale net) respectively, and was varied predominantly by towing speed. Vertical opening (H which is appendixed m for the model net. f for the full-scale net. A and B for the types of the model net) can be expressed as the function of towing velocity$V_t$as in the model net $V_t$ : m/ sec)$H_{mA}$=1.67$e^{-1.65V_t}$ $H_{mB}$=1.15$e^{-1.13V_t}$, in the full-scale net ($V_t$ : k't) $H_{fA}$=50.27$e^-0.37V_t$ $H_{fB}$=34.46$e^{-0.26Vt}$. 2. Horizontal opening of the model nets An and b was varied in the range of 1.03~1.54m and 1.04~1.55 m (which can be converted into 30.9~46.2 m and 31.2~46.5m in the full-scale net) respectively, and was varied predominantly by distance between paired boats. Horizontal opening (W, appendixes are as same as the former) an be expressed as the function of distance between paired boats $D_b$as in the model net $W_{mA}$=0.69+0.09$D_b$ $W{mB}$=0.73+0.09$D_b$, in the full-scale net $W_{fA}$=20.81+0.09$D_b$ $W_{fB}$=22.11+0.09$D_b$ 3. Net opening area of the model net A and B was varied in the range of 0.28~1.04 $m^2$ and 0.33~0.94$m^2$(which can be converted into 252~936$m^2$ and 297~846$m^2$ in the full-scale net) respectively, and was varied predominantly by towing velocity. Net opening area ($S$, appendixes are as same as the former) van be expressed as the function of towing velocity$V_t$ as in the model net $v_t$ : m/sec) $S_{Ma}$=2.01$e^{-1.54V_T}$ $S_{mA}$=1.40$e^{-1.65V_t}$, in the full-scale net ($V_t$ : k't) $S_{fA}$=1.807$e^-0.35V_t$ $S_{fA}$=1.265$e^{-0.24V_t}$. 4. Filtering volume of the model nets A and B was varied in the range of 0.32~0.55 $m^3$ and 0.37~0.55$m^3$(which can be converted into 8.640~14.850 $m^3$ and 9.990~14.850$m3$in the full~scale net) respectively, and was predominantly varied by towing speed. filtering volume of the model net-A showed the maximum at the towing speed 0.69 m/sec(3 k't in the full-scale net), compared with that of the model net B showed at 0.92 m/sec(4 k't in the full-scale net).

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Macrobenthic Faunal Assemblages on the Soft-Bottoms around Dokdo in the East Sea, Korea (한국 동해 독도 주변 천해 및 사면해역의 대형저서동물군집)

  • Choi, Jin-Woo;Hyun, Sang-Min;Kim, Dong-Sung;Kim, Woong-Seo
    • Ocean and Polar Research
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    • v.24 no.4
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    • pp.429-442
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    • 2002
  • The faunal assembalges of macrobenthos and their habitat conditions on the soft-bottoms around Dokdo(Dok Island) was investigated using a box corer and a van Veen grab in Sept. 1999 and May 2000. The sediments in the slope sites were composed of sand particles and those in Ullneung Basin were mud. The sediments in the shelf sites were in the range of fine to medium sand. The organic content of the slope sediments was in the range of 1 to 2%. The macrobenthos occurred at the slope sites represented by 15faunal groups belonging to 8 phyla, and the major faunal group was polychaetous annelids. They comprised ca. 80.6% in slope sites, and 84.8% in shelf sites. Dominant species in the slope were Exogone verugera(40.9%), Cossura longocirrata (8.4%), Tharyx sp. (6.6%), Scalibregma inflatum (4.9%), Aedicira sp. (4.7%), Aricidea ramosa (3.8%), and Sigambra tentaculata (3.7%). Dominant species in the shelf were Chone sp. (49.3%), Tharyx sp. (18.4%), Ophelina acuminata (6.7%), Chaetozone setosa (3.8%), Glycera sp. (2.6%), and Aedicira sp. (2.4%). The mean densities of macrobenthos in the slope and shelf area were $2,028\;ind./m^2$ and $456\;ind./m^2$, respectively. The trophic composition of benthic polychaete worms in the slope area was different from that in shallow shelf area: surface deposit feeding worms were most abundant in slope area whereas filter feeding worms in shelf area. According to the cluster analysis and MDS plots, the spatial distribution of macrobenthos in Dokdo slope region was related with the sediment properties such as particle size and organic content. In the case of vertical distribution of macrobenthos in slope sites, most faunas concentrated in the upper sediment layer within 2cm depth.

The Community Structure of Macrobenthic Assemblages in the Taehwa River Estuary, Ulsan, Korea (울산 태화강 하구역에 서식하는 대형저서동물의 군집구조)

  • Kim, Hyung-Chul;Choi, Byoung-Mi;Jung, Rae-Hong;Lee, Won-Chan;Yun, Jae-Seong;Seo, In-Soo
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.22 no.6
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    • pp.694-707
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    • 2016
  • This study investigated the community structure of macrobenthic assemblages in the Taehwa River Estuary, Ulsan, Korea. Macrobenthos were collected with a Van Veen Grab Sampler during February and November 2012. The total species number and mean density were $176species/9.6m^2$ and $1,992inds./m^2$, respectively. Polychaetes were the most dominant faunal group in terms of species (91 species) and abundance ($1,463inds./m^2$). The major dominant species were polychaetes Minuspio japonica ($609{\pm}1,221inds./m^2$), Hediste japonica ($174{\pm}318inds./m^2$), Tharyx sp.1 ($106{\pm}283inds/m^2$), Lumbrineris longifolia ($79{\pm}207inds./m^2$), bivalve Theora fragilis ($114{\pm}272inds./m^2$) and amphipod Grandidierella japonica ($88{\pm}223inds./m^2$). Based on community statistics (cluster analysis and non-metric multidimensional scaling (nMDS) ordination), the macrobenthic community was divided into three station groups. Group I(freshwater dominated stations 2-6 with coarse sediment) was characterized by a high abundance of polychaetes Minuspio japonica, Hediste japonica, Capitella capitata, Pseudopolydora kempi, amphipods Grandidierella japonica and Apocorophium acutum. Group II (ecotone, stations 7-9 with mixed sediment) was numerically dominated by bivalve Theora fragilis, polychaetes Cirriformia tentaculata, Tharyx sp.1, Lumbrineris longifolia and Chaetozone sp. Finally, Group III (seawater dominated stations 10-12 with fine sediment) was characterized by a high density of polychaete Magelona japonica. These results showed that changes in salinity gradient and sedimentary characteristics were the main factors behind spatial changes in the macrobenthic communities of the Taehwa River Estuary.

Human metapneumovirus infection in Korean children (소아에서 human metapneumovirus 감염)

  • Yeom, Hee-Hyun;Park, Joon-Soo;Jeong, Dong-Jun;Kim, Chang-Jin;Kim, Yong-Bae;Lee, Dea-Hoon;Kim, Kyung-Joong;Chun, Jong-Yoon;Kang, Chun;Chung, Yoon-Seok;Cheong, Hyang-Min
    • Clinical and Experimental Pediatrics
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    • v.49 no.4
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    • pp.401-409
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    • 2006
  • Purpose : Human metapneumovirus(hMPV) is a respiratory viral pathogen that causes a wide spectrum of illnesses, ranging from asymptomatic infection to severe bronchiolitis. The virus has been identified world widely, but so far it has not been published in Korea. Methods : We obtained clinical samples by nasopharyngeal aspiration from 218 children hospitalized due to acute lower respiratory tract infections at Soonchunhyang University Hospital in Cheonan from October, 2004 to April, 2005. We designed specific primers from conserved region of fusion glycoprotein of hMPV. Total RNA was extracted and RT-PCR was performed, and single specific 423 bp product was obtained. The PCR product was confirmed to be fusion glycoprotein RNA by sequencing. Results : We detected hMPV in 15(6.9 percent) of the 218 hospitalized children. The infected children comprised nine boys and six girls; their mean age was 2.8 years(5 mo-12 yrs) and they were diagnosed with pneumonia(60 percent), bronchiolitis(33.3 percent), croup(6.6 percent). The number of cases of detected hMPV in Korea increased dramatically during the period from March to May 2005. Conclusion : hMPV is circulating in Korean children and is associated with respiratory tract infection. Additional studies are required to define the epidemiology and the extent of diseases in the general population caused by hMPV.

Community Structure of Macrobenthos in the Subtidal Soft Bottom in Semi- enclosed Youngsan River Estuarine Bay, Southwest Coast of Korea (반폐쇄적인 영산강 하구역 조하대 연성저질의 저서동물 군집)

  • LIM Hyun-Sig;PARK Kyung-Yang
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.3
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    • pp.320-332
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    • 1999
  • Investigations were made on the community structure of macrobenthos in the subtidal soft bottom around semi-enclosed Youngsan River estuarine bay, southwest coast of Korea during the period from April 1995 to February 1996. Three macrobenthos samples were collected at 40 stations using a van Veen grab(0.1 m^2) during the study period. A total of 206 species of macrobenthos was identified. Their mean density and biomass (wet-weight, wwt) were $1,137 ind./m^2$ and $65.28 gwwt/m^2$, respectively. Of these, there were 74 species of polychaetes ($36\%$), 60 molluscs ($39\%$), 51 crustaceans ($25\%$) and 21 miscellaneous taxa. Molluscs were represented as a density- and biomass-dominant faunal group with a mean density of $601 ind./m^2$($53\%$ of the total benthic animals) and biomass of $25.37 gwwt/m^2$($39\%$ of total biomass): It was followed by polychaetes with $405 ind./m^2$($40\%$ of the total density). Total number of species and diversity were Bow in the inner estuarine bay containing high mud content and organic matter, whereas they were high in the outer stations containing low mud content and organic matter. Major dominant species were one biralve, Theora fragilis and three Polychaetes, Tharyx sp., Poeciloceatus johnonni and Lumbrineris lontifolia whose mean densities were $490ind./m^2$, $96ind./m^2$, $74ind./m^2$and $52 ind./m^2$, respectively. Cluster analysis indicated that the study area could be divided into four station groups: two innermost station groups, a central bay and an outer station group. The species diversity increased from the inner station group toward the outer groups. These results were discussed in terms of both the environmental factors and distribution of benthic community.

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Fault reactivation potential during $CO_2$ injection in the Gippsland Basin, Australia (호주 Gippsland Basin에서 $CO_2$ 주입 중 단층 재활성화의 가능성)

  • Ruth, Peter J. van;Nelson, Emma J.;Hillis, Richard R.
    • Geophysics and Geophysical Exploration
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    • v.9 no.1
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    • pp.50-59
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    • 2006
  • The risk of fault reactivation in the Gippsland Basin was calculated using the FAST (Fault Analysis Seal Technology) technique, which determines fault reactivation risk by estimating the increase in pore pressure required to cause reactivation within the present-day stress field. The stress regime in the Gippsland Basin is on the boundary between strike-slip and reverse faulting: maximum horizontal stress $({\sim}\;40.5\;Mpa/km)$ > vertical stress (21 Mpa/km) ${\sim}$ minimum horizontal stress (20 MPa/km). Pore pressure is hydrostatic above the Campanian Volcanics of the Golden Beach Subgroup. The NW-SE maximum horizontal stress orientation $(139^{\circ}N)$ determined herein is broadly consistent with previous estimates, and verifies a NW-SE maximum horizontal stress orientation in the Gippsland Basin. Fault reactivation risk in the Gippsland Basin was calculated using two fault strength scenarios; cohesionless faults $(C=0;{\mu}=0.65)$ and healed faults $(C=5.4;\;{\mu}=0.78)$. The orientations of faults with relatively high and relatively low reactivation potential are almost identical for healed and cohesionless fault strength scenarios. High-angle faults striking NE-SW are unlikely to reactivate in the current stress regime. High-angle faults oriented SSE-NNW and ENE-WSW have the highest fault reactivation risk. Additionally, low-angle faults (thrust faults) striking NE-SW have a relatively high risk of reactivation. The highest reactivation risk for optimally oriented faults corresponds to an estimated pore pressure increase (Delta-P) of 3.8 MPa $({\sim}548\;psi)$ for cohesionless faults and 15.6 MPa $({\sim}2262\;psi)$ for healed faults. The absolute values of pore pressure increase obtained from fault reactivation analysis presented in this paper are subject to large errors because of uncertainties in the geomechanical model (in situ stress and rock strength data). In particular, the maximum horizontal stress magnitude and fault strength data are poorly constrained. Therefore, fault reactivation analysis cannot be used to directly measure the maximum allowable pore pressure increase within a reservoir. We argue that fault reactivation analysis of this type can only be used for assessing the relative risk of fault reactivation and not to determine the maximum allowable pore pressure increase a fault can withstand prior to reactivation.

Optimal Spatial Scale for Land Use Change Modelling : A Case Study in a Savanna Landscape in Northern Ghana (지표피복변화 연구에서 최적의 공간스케일의 문제 : 가나 북부지역의 사바나 지역을 사례로)

  • Nick van de Giesen;Paul L. G. Vlek;Park Soo Jin
    • Journal of the Korean Geographical Society
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    • v.40 no.2 s.107
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    • pp.221-241
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    • 2005
  • Land Use and Land Cover Changes (LUCC) occur over a wide range of space and time scales, and involve complex natural, socio-economic, and institutional processes. Therefore, modelling and predicting LUCC demands an understanding of how various measured properties behave when considered at different scales. Understanding spatial and temporal variability of driving forces and constraints on LUCC is central to understanding the scaling issues. This paper aims to 1) assess the heterogeneity of land cover change processes over the landscape in northern Ghana, where intensification of agricultural activities has been the dominant land cover change process during the past 15 years, 2) characterise dominant land cover change mechanisms for various spatial scales, and 3) identify the optimal spatial scale for LUCC modelling in a savanna landscape. A multivariate statistical method was first applied to identify land cover change intensity (LCCI), using four time-sequenced NDVI images derived from LANDSAT scenes. Three proxy land use change predictors: distance from roads, distance from surface water bodies, and a terrain characterisation index, were regressed against the LCCI using a multi-scale hierarchical adaptive model to identify scale dependency and spatial heterogeneity of LUCC processes. High spatial associations between the LCCI and land use change predictors were mostly limited to moving windows smaller than 10$\times$10km. With increasing window size, LUCC processes within the window tend to be too diverse to establish clear trends, because changes in one part of the window are compensated elsewhere. This results in a reduced correlation between LCCI and land use change predictors at a coarser spatial extent. The spatial coverage of 5-l0km is incidentally equivalent to a village or community area in the study region. In order to reduce spatial variability of land use change processes for regional or national level LUCC modelling, we suggest that the village level is the optimal spatial investigation unit in this savanna landscape.

Immunogenicity, Reactogenicity and Safety of a Combined DTPa-IPV Vaccine Compared with Separate DTPa and IPV Vaccines in Healthy Korean Infants (한국의 건강한 영아를 대상으로 DTPa-IPV 혼합백신을 접종한 경우와 DTPa 백신과 IPV 백신을 각각 투여하였을 경우의 면역원성, 반응원성 및 안전성)

  • Kim, Chang Hwi;Cha, Sung Ho;Shin, Son Moon;Kim, Chun Soo;Choi, Young Youn;Hong, Young Jin;Chey, Myoung Jae;Kim, Kwang Nam;Hur, Jae Kyun;Jo, Dae Sun;Kim, Sung Shin;Lee, Sang Lak;Song, Eun Song;Ramakrishnan, Gunasekaran;Ok, Jin Ju;Van Der Meeren, Olivier;Bock, Hans L.;Kim, Jung Soo
    • Pediatric Infection and Vaccine
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    • v.17 no.2
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    • pp.156-168
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    • 2010
  • Purpose : To compare immunogenicity and reactogenicity of a combined diphtheria-tetanus-acellular pertussis-inactivated poliovirus vaccine (DTPa-IPV, $Infanrix^{TM}$ IPV, GlaxoSmithKline Biologicals) with co-administration of commercially available DTPa and IPV vaccines at separate injection sites (DTPa+IPV). Methods : A total of 458 infants aged 8-12 weeks were randomized to receive three-ose primary vaccination at 2, 4 and 6 months with DTPa-IPV or DTPa+IPV. Blood samples were collected pre and post vaccination for measurement of immune responses. Reactogenicity was assessed following each dose using diary cards. Results : One month post-dose 3, seroprotection rates for anti-diphtheria, anti-tetanus and anti-poliovirus types 1, 2 and 3 were ${\geq}99.5%$ and vaccine response rates to pertussis antigens were at least 98.6% in both DTPa-IPV and DTPa + IPV groups. Non-inferiority between the groups was demonstrated based on pre-defined statistical criteria. Incidences of both local and systemic symptoms were within the same range across both groups with grade 3 symptoms reported following no more than 4.3% of DTPa-IPV doses and 4.5% of DTPa + IPV doses. Two serious adverse events (both pyrexia) after DTPa-IPV administration were considered vaccine-related. Both infants recovered fully. Conclusion : Combined DTPa-IPV vaccine was immunogenic and well tolerated when used as a three-dose primary vaccination course in Korean infants. DTPa-IPV could be incorporated into the Korean vaccination schedule, reducing the number of injections required to complete primary immunization.