• Title/Summary/Keyword: V-R mechanism

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The Experimental Study of Cheonghunhwadam-tang Gamypang on the Regional Cerebral Blood Flow and Mean Arterial Blood Pressure in Rats(III) (청훈화담탕가미방이 국소뇌혈류량 평균혈압에 미치는 실험적 연구(III))

  • Jeong Hyun Woo;Rho Young Ho;Kim Cheon Joong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.3
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    • pp.746-750
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    • 2003
  • Cheonghunhwadam-tang have been used in oriental medicine for many centuries as a therapeutic agent of vertigo by wind, fire and phlegm. CHT Gamypang(CTG) was CHT adding Aurantii Fructus(AF). The effects of CTG on the regional cerebral blood f1ow(rCBF) and mean arterial blood pressure(MABP) is not known. The mechanical Study of CTG on the cerebral hemodynamics is not known too. Therefore, purpose of this Study was to investigate effects of CTG on the rCBF and MABP, mechanism of CTG on the cerebral hemodynamics in rats. The changes of rCBF and BP was determinated by Laser-Doppler Flowmetry(LDF). The results were as follows ; CTG extract was significantly decreased rCBF in a dose-dependent, but the change of MABP was not shown. Pretreatment with propranolol(3mg/kg, i.v.) was significantly increased CTG(10 mg/kg, i.v.) induced decrease of rCBF. Pretreatment with indomethacin(3mg/kg, i.v.) and methylene blue(10㎍/kg, i.v.) were increased CTG induced decrease of rCBF too. This results suggest that the mechanism of CTG is mediated by adrenergic β - receptor, guanylate cyclase and cyclooxygenase.

An Experimental Study on the High Performance Optimal Discharge System of a Rotary Compressor for an Air Conditioner using alternative Refrigerant R410a (대체냉매 공기조화기용 로터리 압축기의 성능향상을 위한 최적 토출계에 관한 실험적 연구)

  • Youn, Young;Chung, Jin-Taek;Min, Man-Ki
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.13 no.2
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    • pp.96-105
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    • 2001
  • R410a which is one of HFC refrigerants is being considered to be a promising replacement for R22 widely used in domestic air conditioners. The rolling piston type rotary compressors for R410a have lower energy efficiency than those for R22 because of the high pressure difference between a suction chamber and a discharge chamber in the compression mechanism. in addition, the re-expansion gas loss of the rotary compressor for R410a which occurs a ta clearance volume in a discharge port becomes larger than that for R22 due to high density of R410a refrigerant. Therefore, Pressure-Volume analyses for various design parameters of a discharge system were carried out to improve efficiency of a R410a rotary compressor. The results such as performance dta, over-compression loss, and re-expansion loss were acquired by P-V analyses and analyzed quantitatively. As a conclusion, the optimal specifications of several design parameters of a discharge system were obtained by analyzing P-V diagrams.

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Mechanism of Naproxen-Induced Antidiuretic Response in Dog (나프록센의 항이뇨작용 기전)

  • 고석태;이한구;유강준
    • YAKHAK HOEJI
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    • v.39 no.3
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    • pp.314-328
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    • 1995
  • This study was attempted to investigate the mechanism of retention of sodium and water by naproxen which is a drug among nonsteroidal anti-inflammatory drugs in dogs. Napoxen, when given intravenously in doses ranging from 30 mg to 100 mg/kg, elicited antidiuresis accompanied vath the decrease of osmolar clearance(Cosm) and amounts of sodium excreted in urine(E$_{Na}$), with the increase of sodium reabsorption rate in renal tubule(R$_{Na}$) and ratio of potassium against sodium (K/Na). Naproxen infused into a renal artery in doses ranging from 1.0mg to 3.0mg/kg/min produced both diuretic action in infused kidney and antidiuretic action in control kidney. Naproxen injected into carotid artery in doses ranging from 10.0 mg to 30.0 mg/kg exhibited antidiuretic action. Changes of renal function in the circumstances of above two antidiuresis were the same with aspect of intravenous naproxen. Antidiuretic action of naproxen injected into carotid artery was not affected by renal denervation, was blocked by pretreatment with i.v. arachidonic acid, prostaglandin precursor, or i.v. indomethacin, cyclooxygenase inhibitor. Naproxen injected into carotid artery abolished the diuretic action of i.v. spironolactone, aldosterone antagonist, and i.v. spironolactone blocked the antidiuretic action of naproxen given into carotid artery. The results suggest that naproxen produced antidiuresis, and sodium and water retention through the central system, the mechanism being related to the prostaglandin biosynthetic inhibition and aldostercfne like action.

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Acquisition, Processing and Image Generation System for Camera Data Onboard Spacecraft

  • C.V.R Subbaraya Sastry;G.S Narayan Rao;N Ramakrishna;V.K Hariharan
    • International Journal of Computer Science & Network Security
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    • v.23 no.3
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    • pp.94-100
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    • 2023
  • The primary goal of any communication spacecraft is to provide communication in variety of frequency bands based on mission requirements within the Indian mainland. Some of the spacecrafts operating in S-band utilizes a 6m or larger aperture Unfurlable Antenna (UFA for S-band links and provides coverage through five or more S-band spot beams over Indian mainland area. The Unfurlable antenna is larger than the satellite and so the antenna is stowed during launch. Upon reaching the orbit, the antenna is deployed using motors. The deployment status of any deployment mechanism will be monitored and verified by the telemetered values of micro-switch position before the start of deployment, during the deployment and after the completion of the total mechanism. In addition to these micro switches, a camera onboard will be used for capturing still images during primary and secondary deployments of UFA. The proposed checkout system is realized for validating the performance of the onboard camera as part of Integrated Spacecraft Testing (IST) conducted during payload checkout operations. It is designed for acquiring the payload data of onboard camera in real-time, followed by archiving, processing and generation of images in near real-time. This paper presents the architecture, design and implementation features of the acquisition, processing and Image generation system for Camera onboard spacecraft. Subsequently this system can be deployed in missions wherever similar requirement is envisaged.

Analysis of Gas Response Characteristics of Maleate Organic Ultra-thin Films (말레에이트계 유기초박막의 가스 반응 특성 분석)

  • Choe, Yong-Seong;Kim, Jeong-Myeong;Kim, Do-Gyun;Gwon, Yeong-Su
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.48 no.6
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    • pp.442-450
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    • 1999
  • In this paper, we have fabricated Langmuir-Blodgett(LB) films by LB technique and evaluated the deposited status of LB films by UV-vis absorbance. It was found thatthe thickness of LB films per a layer are $27~30[{\AA}]$ by ellipsometry. The responeses between LB films and organic gases were investigated using by I-V characteristics of LB films and F-R diagram of quartz crystal. The response orders between LB films and organic gases observed by I-V characteristics were as following ; chloroform, methanol, acetone and ethanol in the order of their short chain length. The response mechanism between LB films and organic gases observed by F-R diagram of quartz crystal could be modeled on adsorption at surface, penetration, desorption at surface and inside.

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Mechanism of Jaeumgenby-tang adding Aurantii FructusㆍGastrodae Rhizoma on the Improvement and Changes of Cerebral Hemodynamics (자음건비탕가지각ㆍ천마가 뇌혈류역학 변동에 미치는 작용기전)

  • Im Gwang Mo;Park Choul Hoon;Jeong Hyun Woo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.2
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    • pp.416-422
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    • 2003
  • Jaeumgenby-tang(JGT) have been used in oriental medicine for many centuries as a therapeutic agent of vertigo caused by deficiency of qi(氣) and blood(血). Effect of Aurantii Fructus(AF) take off the phlegm by promoting the circulation of qi, Gastrodae Rhizoma(GR) has effects treating for headache, vertigo by calming the liver and suppressing hyperactivity of the liver-yang(陽). And, We reported that JGT adding AFㆍGR extract(JGTAG) was significantly increased regional cerebral blood f1ow(rCBF) by dilating pial arterial diameter(PAD). Therefor we designed to investigate whether JGTAG is mediated by adrenergic β-receptor, cyclooxygenase or guanylate cyclase in normal rats. The changes of rCBF and mean arterial blood pressure(MABP) were determinated by laser-doppler flowmetry(LDF), and the change of PAD was determinated by video microscope and width analyzer. The results were as follows in normal rats; Pretreatment with propranolol(1mg/kg, i.v.) was significantly inhibited JGTAG induced increase of rCBF, PAD and MABP, and pretreatment with indomethacin(1 mg/kg, i.v.) was significantly inhibited too. But pretreatment with methylene blue(10μg/kg, i.v.) were accelerated JGTAG induced increase of rCBF and MABP, but pretreatment with methylene blue was inhibited JGTAG induced increase of PAD. This results suggest that the mechanism of JGTAG is mediated by adrenergic β-receptor and cyclooxygenase.

Inferring candidate regulatory networks in human breast cancer cells

  • Jung, Ju-Hyun;Lee, Do-Heon
    • Bioinformatics and Biosystems
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    • v.2 no.1
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    • pp.24-27
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    • 2007
  • Human cell regulatory mechanism is one of suspicious problems among biologists. Here we tried to uncover the human breast cancer cell regulatory mechanism from gene expression data (Marc J. Van de vijver, et. al., 2002) using a module network algorithm which is suggested by Segal, et. al.(2003) Finally, we derived a module network which consists of 50 modules and 10 tree depths. Moreover, to validate this candidate network, we applied a GO enrichment test and known transcription factor-target relationships from Transfac(R) (V. Matys, et. al, 2006) and HPRD database (Peri, S. et al., 2003).

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Hysteresis Behavior in Pentacene Organic Thin-film Transistors

  • So, Myeong-Seob;Suh, Min-Chul;Koo, Jae-Bon;Choi, Byoung-Deog;Choi, Dae-Chul;Lee, Hun-Jung;Mo, Yeon-Gon;Chung, Ho-Kyoon
    • 한국정보디스플레이학회:학술대회논문집
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    • 2005.07b
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    • pp.1364-1369
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    • 2005
  • In this paper, we have identified the mechanism of C-V hysteresis behavior often observed in pentacene organic thin-film transistors (OTFTs). The capacitance-voltage (C-V) characteristics were measured for pentacene OTFTs fabricated on glass substrates with MoW as gate/source/drain electrode and TEOS $SiO_2$ as gate insulator. The measurements were made at room temperature and elevated temperatures. From the room temperature measurements, we found that the hysteresis behavior was caused by hole injection into the gate insulator from the pentacene semiconductor for large negative gate voltages, resulting in the negative flat-band voltage shift. However electron injection was observed only at elevated temperatures

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TIME VARIATION OF SiO (v=1, J=2-1) MASERS OF LONG PERIOD VARIABLES

  • LEE SANG GAK;KIM EUNHYEUK;LEE HYUNG MOK
    • Journal of The Korean Astronomical Society
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    • v.27 no.2
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    • pp.133-146
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    • 1994
  • We have detected a SiO maser line (v=1, J=2- 1) for 15 stars out of about 80 long period variables in the wide range of period. No new sources are detected; all detected sources are variables with period longer than 300 days; no evidence is found that the dust grains in the outer envelope have influenced on this line. The time variation of this maser line for 7 stars, T Cep, ${\mu} Cep$, U Her, R Leo, R Lmi, U Ori, and R Ser is observed and compared with optical light curve at the same epoch of maser observation. No universial relation between the time variation and the optical light curve is found. It implies that the radiation from a central star does not much play an important role for the direct pumping of the SiO maser line.

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Experimental Study of Acupuncture at Haenggan(LR2) on the Cerebral Hemodynamics in Normal Rats (행간(行間) 자침(刺鍼)이 뇌혈류역학(腦血流力學) 작용(作用) 기전(機轉)에 미치는 실험적(實驗的) 연구(硏究))

  • Lee Yoon-Yeong;Na Chang-Su;Ryu Chung-Ryul;Cho Myeng-Rae;Shin Jeong-Chul
    • Korean Journal of Acupuncture
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    • v.20 no.4
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    • pp.31-40
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    • 2003
  • Objectives : The purpose of this study is to investigate whether Haenggan(LR2) Reduction in Acupuncture affects cerebral hemodynamics〔regional cerebral blood flow(rCBF), mean arterial blood pressure(MABP)〕in normal rats, and to make manifest whether Haenggan(LR2) Reduction in Acupuncture is mediated by cyclooxygenase or guanylate cyclase. Methods : This experiments was to investigate at the other changes of rCBF and MABP at Haenggan(LR2) Reduction in Acupuncture in normal rats, pretreated rats with indomethacin(1 mg/kg, i.v.) and pretreated rats with methylene blue$(10\;{\,u}g/kg,\;i.v.)$. Results : 1. Haenggan(LR2) Reduction in Acupuncture was significantly increased rCBF during acupuncture and after withdrawing of the needle. 2. Haenggan(LR2) Reduction in Acupuncture was decreased MABP during acupuncture, but Haenggan(LR2) Reduction in Acupuncture was increased MABP in compared with normal condition. 3. Pretreatment with indomethacin(1 mg/kg, i.v.) was significantly inhibited Haenggan(LR2) Reduction in Acupuncture induced increase of rCBF, but was increased Haenggan(LR2) Reduction in Acupuncture induced increase of MABP. 4. Pretreatment with methylene blue$(10\;{\mu}g/kg,\;i.v.)$ was significantly decreased Haenggan(LR2) Reduction in Acupuncture induced increase of rCBF and MABP. This results suggest that Haenggan(LR2) Reduction in Acupuncture increased rCBF by dilating pial arterial diameter, and the mechanism of Haenggan(LR2) Reduction in Acupuncture is mediated by guanylate cyclase.

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