• Food Science of Animal Resources
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• v.34 no.6
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• pp.844-851
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• 2014

This study focused on the anti-oxidative and collagenase- and elastase inhibition effects of low molecular weight peptides (LMP) from commercial Jeju horse leg bone hydrolysates (JHLB) on pancreatin, via enzymatic hydrolysis. Cell viability of dermal fibroblasts exposed to UVB radiation upon treatment with LMP from JHLB was evaluated. Determination of the antioxidant activity of various concentrations of LMP from JHLB were carried out by assessing 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2-azino-bis-3-ethybenzothiazoline-6-sulphonic acid (ABTS) radical scavenging activity, ferric reducing antioxidant power (FRAP), and oxygen radical absorbance capacity (ORAC). The DPPH radical scavenging activity of LMP from JHLB (20 mg/mL) was 92.21% and ABTS radical scavenging activity (15 mg/mL) was 99.50%. FRAP activity (30 mg/mL) was $364.72{\mu}M/TE$ and ORAC activity (1 mg/mL) was $101.85{\mu}M/TE$. The anti-wrinkle potential was assessed by evaluating the elastase- and collagenase inhibition potential of these LMP. We found that 200 mg/mL of LMP from JHLB inhibited elastase activity by 41.32%, and 100 mg/mL of LMP from JHLB inhibited collagenase activity by 91.32%. The cell viability of untreated HS68 human dermal fibroblasts was 45% when exposed to a UVB radiation dose of $100mJ/cm^2$. After 24 h of incubation with $500{\mu}g/mL$ LMP from JHLB, the cell viability increased to 60%. These results indicate that LMP from JHLB has potential utility as an anti-oxidant and anti-wrinkle agent in the food and cosmetic industry. Additional in vivo tests should be carried out to further characterize these potential benefits.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.10 no.2
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• pp.57-72
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• 2004

Background : The part to be very important that we make the physical development rightly at elementary school student days. Objective : This study investigated the relation of a physical health status which itself recognizes and an exercise performance situation out for an elementary school students. Methods : This cross-sectional study examined health and exercise performance status of 1,032 elementary school children. To examine children's a physical injury experience and injury occurrence characteristic and a personal computer utility condition, a body alignment status of the student which parents recognize and the relation of a fatigue and concentration level was an investigation with other factors. Results: An average age of the children was the 10.95 yr and an average weight was the 39.02 kg and an average height was the 145.17cm. The student to be experiencing currently an pain occurrence was 192(19.07%). It was most high to the grade 6(23.33%) compared with different grade(p<.01). Physical pain occurrence rate did not exist by gender(p>.05). There is most an pain occurrence region the ankle(38.0%). They had a 27.19% an physical injury experience of the students. A injury rate was revealed that were high as were the high grade(grade 6, 36.72%)(p<.01). A reason of the injury rate was high in a collision at the body(19.84%), falling down(18.68%) sequence at a traffic accident(22.96%)(p<.05). There were the significant relation to the school year the reason of the injury (p<.05). Currently there was the student to be taking special exercises a 57.97%. This that they have the relation with exercise with physical pain students to recognize 23.8%. The significant relation did not exist in the physical exercise execution and pain occurrence on the body(p>.05).

• Journal of The Korean Society of Grassland and Forage Science
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• v.17 no.3
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• pp.265-276
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• 1997

This study was investigated the herbage productivity and nutrient contents of corn (Suweon 19 and Kwanganok) and sweet sorghum (Ramiki sorgo and Silage sorgo) at the stage of maturity (10-DBS, silking, milky and dough stages) to identify the utility value of sweet sorghum as a substituting crop for corn. The silage materials (dough stage) were chopped and were storaged for 90 days in polyethlene bag with O.lmm thickness. Chemical composition, nitrogen content and in vitm dry matter digestibility were evaluated. Also, daily intake and palatability were checked in the feeding trial with four male sheep in average weight about 57kg. Both fresh and dry matter yield of corn and sweet sorghum were increased as the maturity processed (P< 0.05), and sweet sorghum showed higher total yield potential than corn. Crude protein content of the cultivars was decreased as the maturity was processed (P< 0.05). Neutral detergent fiber (NDF) content of the cultivars, in general, showed highest at silking stage, followed by 10 days before silking (10-DBS), and milky and dough stages (Pi0.05) in order. Acid detergent fiber (ADF) content was increased as the maturity processed, and it showed the highest value at milk stage. However, the contents of ADF in sorghum plant was decreased during the late maturity. Crude protein content of the silage was not significantly different among cultivars used, while NDF content was highest in Ramiki sorgo, followed by Silage sorgo, Kwanganok and Suweon 19. In v i m DM digestibility of the silage was highest in Kwanganok, followed by Suweon 19, Silage sorgo and Ramiki sorgo. Total N content of the silage was highest in Ramiki sorgo, followed by Suweon 19, Silage sorgo and Kwanganok. DM intake of the silage was highest in Ramiki sorgo, followed by Suweon 19, Silage sorgo and Kwanganok and it was closely related to the palatability value.

• Journal of the Korean Institute of Landscape Architecture
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• v.29 no.1
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• pp.161-167
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• 2001

The purpose of this study is to find out the difference of Zoysia matrella's evaporation in between 100 percent soil and mixed soil with 50 percent of perlite to create green spaces on the artificial ground. It is believed that the weight against the artificial ground will be reduced, provided the vegetation is possible in the circumstance of the mixed sol with 50 percent of perlite. The study employed a modified Makkink's model by Iwasa who had developed the model for estimating Zoysia matrella's evaporation in the natural ground using the Makkink's formula in 1997 at Chiba University, Japan. The parameter of Makkink's formula is the solar radiation. For that reason, the Makkink's formula is simple and easy to measure the parameter and has a high utility. If the outcomes from mixed soil are close to modified Makkinks formula, the modified Makkink's formula will be applied to estimate in the artificial ground with mixed soil with 50 percent of perlite. Weather observation and actual amount of evaporation of Zoysia matrella have been measured, and the relation between weather condition and actual amount of evaporation had been also investigated. In line with this, we found out that there is a relevant relationship between daily average temperature, the modified Makkink's model by Iwasa, and the actual amount of evaporation. As the results of the experiment, the outcomes from mixed soil with 50 percent of perlite have very high relation to 100 percent soil. In addition, mixed soil has more adhesion with water than natural soil. However, it needs to be adequately maintained in terms of fertilization and damage from disease and harmful insects until the gras fastens its roots into the soil. By using mixed soil with 50 percent of perlite, the load from soil on the artificial ground can be reduced. The study on the growth of the grass throughout the plant vegetation and the actual amount of evaporation in the mixed soil with 50 percent of perlite should be performed in the future.

• Neonatal Medicine
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• v.28 no.1
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• pp.14-21
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• 2021

Purpose: Premature infants have immature respiratory control and cerebral autoregulation. We aimed to investigate changes in cerebral oxygenation during apnea with and without peripheral oxygen desaturation in premature infants. Methods: This prospective observational study was conducted at Inha University Hospital. Near-infrared spectroscopy (NIRS)-monitored regional cerebral oxygen saturation (rScO₂) and pulse oximeter-monitored peripheral oxygen saturation (SpO₂) were assessed during the first week of life in 16 stable, spontaneously breathing preterm infants. Apneic episodes that lasted for ≥20 seconds or were accompanied by desaturation or bradycardia were included for analysis. The average rScO₂ value during the 5-minute prior to apnea (baseline), the lowest rScO₂ value following apnea (nadir), the time to recover to baseline (recovery time), the area under the curve (AUC), and the overshoot above the baseline after recovery were analyzed. Results: The median gestational age and birth weight of the infants were 29.2 weeks (interquartile range [IQR], 28.5 to 30.5) and 1,130 g (IQR, 985 to 1,245), respectively. A total of 73 apneic episodes were recorded at a median postnatal age of 2 days (IQR, 1 to 4). The rScO₂ decreased significantly following apneic episodes regardless accompanied desaturation. There were no differences in baseline, nadir, or overshoot rScO₂ between the two groups. However, the rScO₂ AUC for apnea with desaturation was significantly higher than that for apnea without desaturation. Conclusion: Cerebral oxygenation can significantly decrease during apnea, especially when accompanied by reduced SpO₂. These results add the evidence for the clinical utility of NIRS in monitoring premature infants.

• Journal of Veterinary Science
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• v.22 no.3
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• pp.30.1-30.15
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• 2021

Background: New-generation adjuvants for foot-and-mouth disease virus (FMDV) vaccines can improve the efficacy of existing vaccines. Chinese medicinal herb polysaccharide possesses better promoting effects. Objectives: In this study, the aqueous extract from Artemisia rupestris L. (AEAR), an immunoregulatory crude polysaccharide, was utilized as the adjuvant of inactivated FMDV vaccine to explore their immune regulation roles. Methods: The mice in each group were subcutaneously injected with different vaccine formulations containing inactivated FMDV antigen adjuvanted with three doses (low, medium, and high) of AEAR or AEAR with ISA-206 adjuvant for 2 times respectively in 1 and 14 days. The variations of antibody level, lymphocyte count, and cytokine secretion in 14 to 42 days after first vaccination were monitored. Then cytotoxic T lymphocyte (CTL) response and antibody duration were measured after the second vaccination. Results: AEAR significantly induced FMDV-specific antibody titers and lymphocyte activation. AEAR at a medium dose stimulated Th1/Th2-type response through interleukin-4 and interferon-γ secreted by CD4⁺ T cells. Effective T lymphocyte counts were significantly elevated by AEAR. Importantly, the efficient CTL response was remarkably provoked by AEAR. Furthermore, AEAR at a low dose and ISA-206 adjuvant also synergistically promoted immune responses more significantly in immunized mice than those injected with only ISA-206 adjuvant and the stable antibody duration without body weight loss was 6 months. Conclusions: These findings suggested that AEAR had potential utility as a polysaccharide adjuvant for FMDV vaccines.

• Hip & pelvis
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• v.30 no.4
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• pp.219-225
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• 2018

Purpose: Ischiofemoral impingement (IFI)-primarily diagnosed by magnetic resonance imaging (MRI)-is an easily overlooked disease due to its low incidence. The purpose of this study was to evaluate the usefulness of false profile view as a screening test for IFI. Materials and Methods: Fifty-eight patients diagnosed with IFI between June 2013 and July 2017 were enrolled in this retrospective study. A control group (n=58) with matching propensity scores (age, gender, and body mass index) were also included. Ischiofemoral space (IFS) was measured as the shortest distance between the lateral cortex of the ischium and the medial cortex of lesser trochanter in weight bearing hip anteroposterior (AP) view and false profile view. MRI was used to measure IFS and quadratus femoris space (QFS). The receiver operating characteristics (ROC), area under the ROC curve (AUC) and cutoff point of the IFS were measured by false profile images, and the correlation between the IFS and QFS was analyzed using the MRI scans. Results: In the false profile view and hip AP view, patients with IFI had significantly decreased IFS (P<0.01). In the false profile view, ROC AUC (0.967) was higher than in the hip AP view (0.841). Cutoff value for differential diagnosis of IFI in the false profile view was 10.3 mm (sensitivity, 88.2%; specificity, 88.4%). IFS correlated with IFS (r=0.744) QFS (0.740) in MRI and IFS (0.621) in hip AP view (P<0.01). Conclusion: IFS on false profile view can be used as a screening tool for potential IFI.

• Journal of Biomedical Engineering Research
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• v.42 no.6
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• pp.268-276
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• 2021

Functional near-infrared spectroscopy-based brain-computer interface (fNIRS-based BCI) has been receiving much attention. However, we are practically constrained to obtain a lot of fNIRS data by inherent hemodynamic delay. For this reason, when employing machine learning techniques, a problem due to the high-dimensional feature vector may be encountered, such as deteriorated classification accuracy. In this study, we employ an elastic net-based feature selection which is one of the embedded methods and demonstrate the utility of which by analyzing the results. Using the fNIRS dataset obtained from 18 participants for classifying brain activation induced by mental arithmetic and idle state, we calculated classification accuracies after performing feature selection while changing the parameter α (weight of lasso vs. ridge regularization). Grand averages of classification accuracy are 80.0 ± 9.4%, 79.3 ± 9.6%, 79.0 ± 9.2%, 79.7 ± 10.1%, 77.6 ± 10.3%, 79.2 ± 8.9%, and 80.0 ± 7.8% for the various values of α = 0.001, 0.005, 0.01, 0.05, 0.1, 0.2, and 0.5, respectively, and are not statistically different from the grand average of classification accuracy estimated with all features (80.1 ± 9.5%). As a result, no difference in classification accuracy is revealed for all considered parameter α values. Especially for α = 0.5, we are able to achieve the statistically same level of classification accuracy with even 16.4% features of the total features. Since elastic net-based feature selection can be easily applied to other cases without complicated initialization and parameter fine-tuning, we can be looking forward to seeing that the elastic-based feature selection can be actively applied to fNIRS data.

• Journal of Information Technology Services
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• v.22 no.2
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• pp.71-92
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• 2023

Globally, under the leadership of advanced ICT countries, the private sector is promoting various policies to promote the digital transformation of public services. Looking at the research trend, design of public service indicators, development of evaluation system, and empirical research are being carried out steadily, but there are insufficient research cases on models in which the private sector participates in the planning, development, and operation of public services. In this study, Private-centric digital public service suitability evaluation indicators were discovered through interviews with experts in various fields, and weights for each indicator were analyzed through AHP evaluation. In addition, by applying the analysis results to 18 digital public services on a trial basis, the importance and priority of evaluation indicators for each service were derived, and at the same time, the evaluation framework was designed and applied to diagnose implications. As a result of the study, 'social utility', 'corporate acceptability', and 'public acceptability' were selected as the top three indicators of suitability evaluation. At this time, it was analyzed that the weight of the 'company acceptability' index, which includes sub-indices such as 'service profitability', 'service scalability', and 'private initiative possibility', was the highest among the three top indicators. As a result of the demonstration for public services, "IoT facility unmanned remote monitoring service", "blockchain real estate transaction service", and "digital twin disaster prediction service" were evaluated as the most suitable public services for the transition to the private sector.

• The Journal of the Acoustical Society of Korea
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• v.41 no.6
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• pp.647-654
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• 2022

Although the fields in which is utilized children's speech recognition is on the rise, the lack of quality data is an obstacle to improving children's speech recognition performance. This paper proposes a new method for improving children's speech recognition performance by additionally using adult speech data. The proposed method is a transformer based domain adversarial training using dynamically weighted loss to effectively address the data imbalance gap between age that grows as the amount of adult training data increases. Specifically, the degree of class imbalance in the mini-batch during training was quantified, and the loss function was defined and used so that the smaller the data, the greater the weight. Experiments validate the utility of proposed domain adversarial training following asymmetry between adults and children training data. Experiments show that the proposed method has higher children's speech recognition performance than traditional domain adversarial training method under all conditions in which asymmetry between age occurs in the training data.