• Korean Journal of Culture and Social Issue
• /
• v.9 no.2
• /
• pp.61-78
• /
• 2003

The researcher examined the relationship between dating violence and drinking behaviors. Study participants included 440 Korean College students(184 males and 256 females) currently involved in heterosexual dating relationships. Participants' ages ranged from 17 to 30(M=20.08, SD=1.89). Questionnaires and psychological tests used included: Straus' Conflict Tactics Scale, Alcohol Use Disorder Identification Test(AUDIT), Cooper's Revised Drinking Motives Questionnaire(DMQ), and Index of Family Alcohol Use. Research designs were 2(gender) × 2(experience of inflicting dating violence), i.e. 2-way MANOVAs. Results suggest students who drink one or more times a week are more likely to commit acts of violence toward their dating partners than students drinking less often. The study revealed males tend to drink with higher social, enhancement, conformity and coping motives than females. The study also showed that students inflicting dating violence drank with higher coping motives than students who did not. Males showed more hazardous, dependent and harmful drinking patterns than females. Also, students who had inflicted dating violence showed a higher degree of these characteristics (hazardous, dependent and harmful drinking patterns) along with a greater family history of alcohol use than participants who had not inflicted dating violence. The findings showed significant 2-way interactions in dependent and harmful drinking patterns. Simple main effect analysis revealed that differences in dependent and harmful drinking patterns in males are more significant than the same differences in females.

• The Journal of Information Systems
• /
• v.17 no.3
• /
• pp.255-287
• /
• 2008

This study examined the relationship among constructs that impact on strategic use of IS(Information Systems). Independent variables were OIQ(Organizational Intelligence Quotient) and role of CIO(Chief of Information Officer) as a top manager, and dependent variable are strategic use of IS. The dependent variable has three-sub constructs: 1) IT infrastructure flexibility; 2) operation-orientation; and 3) market-orientation. Seven research hypotheses derived from the research model, and were empirically tested using the PLS (Partial Least Squares) method. The research results confirmed that both OIQ and CIO's roles have strong impact on organizations' strategic use of IS. Communication and business network among the sub-constructs of OIQ have effect on strategic use of IS. CIO's role as a top manager was found to be significant. CIO's role as a resource allocator and innovator among the CIO's roles showed significant influence on strategic use of IS. OIQ was also significantly related to CIO's role as a top manager. This study suggests practical implications and insights to the enterprises which aim to apply IT strategically.

• The Korean Journal of Physiology and Pharmacology
• /
• v.24 no.6
• /
• pp.545-553
• /
• 2020

Aripiprazole is a quinolinone derivative approved as an atypical antipsychotic drug for the treatment of schizophrenia and bipolar disorder. It acts as with partial agonist activities at the dopamine D2 receptors. Although it is known to be relatively safe for patients with cardiac ailments, less is known about the effect of aripiprazole on voltage-gated ion channels such as transient A-type K⁺ channels, which are important for the repolarization of cardiac and neuronal action potentials. Here, we investigated the effects of aripiprazole on Kv1.4 currents expressed in HEK293 cells using a whole-cell patch-clamp technique. Aripiprazole blocked Kv1.4 channels in a concentration-dependent manner with an IC₅₀ value of 4.4 μM and a Hill coefficient of 2.5. Aripiprazole also accelerated the activation (time-to-peak) and inactivation kinetics. Aripiprazole induced a voltage-dependent (δ = 0.17) inhibition, which was use-dependent with successive pulses on Kv1.4 currents without altering the time course of recovery from inactivation. Dehydroaripiprazole, an active metabolite of aripiprazole, inhibited Kv1.4 with an IC₅₀ value of 6.3 μM (p < 0.05 compared with aripiprazole) with a Hill coefficient of 2.0. Furthermore, aripiprazole inhibited Kv4.3 currents to a similar extent in a concentration-dependent manner with an IC₅₀ value of 4.9 μM and a Hill coefficient of 2.3. Thus, our results indicate that aripiprazole blocked Kv1.4 by preferentially binding to the open state of the channels.

• The Korean Journal of Physiology and Pharmacology
• /
• v.27 no.4
• /
• pp.399-406
• /
• 2023

Voltage-dependent K⁺ (Kv) channels are widely expressed on vascular smooth muscle cells and regulate vascular tone. Here, we explored the inhibitory effect of encainide, a class Ic anti-arrhythmic agent, on Kv channels of vascular smooth muscle from rabbit coronary arteries. Encainide inhibited Kv channels in a concentration-dependent manner with an IC₅₀ value of 8.91 ± 1.75 μM and Hill coefficient of 0.72 ± 0.06. The application of encainide shifted the activation curve toward a more positive potential without modifying the inactivation curve, suggesting that encainide inhibited Kv channels by altering the gating property of channel activation. The inhibition by encainide was not significantly affected by train pulses (1 and 2 Hz), indicating that the inhibition is not use (state)-dependent. The inhibitory effect of encainide was reduced by pretreatment with the Kv1.5 subtype inhibitor. However, pretreatment with the Kv2.1 subtype inhibitor did not alter the inhibitory effects of encainide on Kv currents. Based on these results, encainide inhibits vascular Kv channels in a concentration-dependent and use (state)-independent manner by altering the voltage sensor of the channels. Furthermore, Kv1.5 is the main Kv subtype involved in the effect of encainide.

• Proceedings of the Korean Society for Quality Management Conference
• /
• 2006.11a
• /
• pp.195-198
• /
• 2006

In this paper, we propose a 2dimension Control Chart. Suggested which Control chart augments Schwart Control chart which is 1-dimensional and Independent variable and dependent variable interrelationship by using control chart. Schwart control chart cannot use input variable and output variable together. In this paper, we try to analysis input variable and output variable dependent and effect. So called 2-dimensional control char.

• Atmosphere
• /
• v.22 no.3
• /
• pp.309-319
• /
• 2012

It is important to characterize and quantify the inherent error in the radar rainfall to make full use of the radar rainfall. This study verified the error structure of the reflectivity and corrected the range dependent error in the CAPPI using a VPR (vertical profile of reflectivity) model. The error of the CAPPI to display the reflectivity data becomes bigger for the range longer than 100 km. This range dependent error, however, is significantly improved by corrected the CAPPI data using the VPR model.

• Korean Journal of Computational Design and Engineering
• /
• v.19 no.1
• /
• pp.61-67
• /
• 2014

This paper proposes a procedure enabling the extraction of view-dependent triangular approximations from a height map. In general, procedures to approximate a height map use tree hierarchies. These methods, however, have a limitation in terms of accuracy, because they depend on tree hierarchy than terrain features. To overcome the difficult, we apply the simplification method for triangular meshes to a height map. The proposed procedure maintains full decimation procedure to support multiresolution. The maintenance of decimation procedure results in creation of the groups (trees), each of which consists of vertices that can be merged into one vertex (root node). As the groups have tolerance which is determined by some tests, they support the generation of view-dependent arbitrary triangular meshes.

• Proceedings of the KIEE Conference
• /
• 1999.07a
• /
• pp.61-63
• /
• 1999

This paper presents an efficient method for analysis of magnetodynamic system using frequency-dependent parameters. In equivalent electric circuit of linear magnetodynamic system, parameters of inductance and resistance are not constant since they vary with its driving frequency. Once frequency-dependent parameters of equivalent electric circuit for a given system are extracted, they can be used to analyze various characteristics of system. We use the Fourier transform, the high-order sensitivity method and Taylor series in order to efficiently extract the frequency-dependent parameters of magnetodynamic system. The proposed algorithm is applied to an induction heating system to validate its numerical efficiency.

• Journal of the Korean Data and Information Science Society
• /
• v.24 no.4
• /
• pp.877-883
• /
• 2013

The quadratic inference functions (QIF) method proposed by Qu et al. (2000) and the generalized method of moments (GMM) for marginal regression analysis of longitudinal data with time-dependent covariates proposed by Lai and Small (2007) both are the methods based on generalized method of moment (GMM) introduced by Hansen (1982) and both use generalized estimating equations (GEE). Lai and Small (2007) divided time-dependent covariates into three types such as: Type I, Type II and Type III. In this paper, we compared these methods in the case of Type II and Type III in which full covariates conditional mean assumption (FCCM) is violated and interested in whether they can improve the results of GEE with independence working correlation. We show that in the marginal regression model with Type II time-dependent covariates, GMM Type II of Lai and Small (2007) provides more ecient result than QIF and for the Type III time-dependent covariates, QIF with independence working correlation and GMM Type III methods provide the same results. Our simulation study showed the same results.

• The Transactions of the Korean Institute of Electrical Engineers A
• /
• v.52 no.11
• /
• pp.632-638
• /
• 2003

Modern power systems are very complex and to model them completely is impractical for electromagnetic transient studies. Therefore areas outside the immediate area of interest must be represented by some form of frequency dependent equivalent. The s-domain rational function form of frequency dependent equivalent does not need refitting if the simulation time-step is changed in the electromagnetic transient program. This is because the s-domain rational function coefficients are independent of the simulation time-step, unlike the z-domain rational function coefficients. S-domain rational function fitting techniques for representing frequency dependent equivalents have been developed using Least Squares Fitting(LSF). However it does not suffer the implementation error that exited in this work as it ignored the instantaneous term. This paper Presents the formulation for developing 1 Port Frequency Dependent Network Equivalent(FDNE) with the instantaneous term in S-domain and illustrates its use. This 1 port FDNE have been applied to the CIGRE Benchmark Rectifier test AC system. The electromagnetic transient package PSCAD/EMTDC is used to assess the transient response of the 1 port (FDNE) developed with Thevenin and Norton Equivalent network. The study results have indicated the robustness and accuracy of 1 port FDNE for electromagnetic transient studies.