• 패션비즈니스
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• 제20권4호
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• pp.128-140
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• 2016

In this study, dyeability of Urtica Dioica L. extract, which is relatively less studied, was measured. The extract of this plant was used to dye cellulose and protein fiber to check its usage as a natural green dye. Three different methods were used to produce extract. Dried Urtica Dioica L. was extracted with 100% ethanol, 50% ethanol with 50% distilled water and 100% distilled water. Then dyeing solution was obtained by blending with distilled water at 1-to-1 ratio. The maximum dyeability was obtained when 100% ethanol extract of dried Urtica Dioica L. used to dye fabrics at 60 degrees celsius for 60 minutes without mordant treatment. Cotton, rayon, wool and silk were dyed and dyeability for each fiber was measured for color difference value then compared to its control. The results show that dyeability of rayon and dyeability of wool are stronger, and that when color position for each mordant is measured, color difference is most diverse on cotton with pre-mordant treatment. Color fastness to wash, perspiration and rubbing crockmeter were superb, but color fastness to light was low, therefore, additional study on this is needed to improve. Urtica Dioica L. is now expected to be used practically as green color dye as well as medicinally and edible.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5317-5323
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• 2013

Breast cancer is the most prevalent cancer and one of the leading causes of death among women in the world. Plants and herbs may play an important role in complementary or alternative treatment. The aim of this study was to evaluate the antioxidant and anti-proliferative potential of Urtica dioica. The anti oxidant activity of an aqueous extract of Urtica dioica leaf was measured by MTT assay and the FRAP method while its anti-proliferative activity on the human breast cancer cell line (MCF-7) and fibroblasts isolated from foreskin tissue was evaluated using MTT assay. Mechanisms leading to apoptosis were also investigated at the molecular level by measuring the amount of anti and pro-apoptotic proteins and at the cellular level by studying DNA fragmentation and annexin V staining by flow cytometry. The aqueous extract of Urtica dioica showed antioxidant effects with a correlation coefficient of $r^2$=0.997. Dose-dependent and anti-proliferative effects of the extract were observed only on MCF-7 cells after 72 hrs with an $IC_{50}$ value of 2 mg/ml. This anti proliferative activity was associated with an increase of apoptosis as demonstrated by DNA fragmentation, the appearance of apoptotic cells in flow cytometry analysis and an increase of the amount of calpain 1, calpastatin, caspase 3, caspase 9, Bax and Bcl-2, all proteins involved in the apoptotic pathway. This is the first time such in vitro antiproliferative effect of aqueous extract of Urtica dioica leaf has been described for a breast cancer cell line. Our findings warrant further research on Urtica dioica as a potential chemotherapeutic agent for breast cancer.

• 한국균학회지
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• 제45권2호
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• pp.160-166
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• 2017

The genus Pseudoperonospora (Peronosporales, Oomycota) comprises six accepted species, including Ps. cubensis, which causes downy mildew on many economically important cucurbitaceous crops, and Ps. humuli, which occurs on hops. During a survey of downy mildew flora in Korea, a previously unreported species of Pseudoperonospora was found on Urtica angustifolia. Based on molecular phylogenetic and morphological analyses, the causal agent was identified as Pseudoperonospora urticae. This is the first report of Pseudoperonospora urticae occurring on Urtica angustifolia in Korea.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1996년도 춘계학술대회
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• pp.168-168
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• 1996

가는잎쇄기풀(Urtica angustifolia Fisch.)은 쇄기풀과(Urticaceae)에 속하는 다년생 초본으로 중약 또는 민간에서 동속 근연식물과 함께 전초를 담마라하여 류마치스성 동통, 산후의 산풍, 소아의 추풍, 경풍,담마진의 치료에 사용되고 있다. Rat에서 실험적 항당뇨 효과를 검토해본 결과 혈당강하 작용이 있는 본 식물로부터 그 혈당강하 성분의 분리에 앞서 식물화학 성분을 규명하고자 본 실험에 착수하였다. 가는잎쇄기풀 전초의 MeOH ex.를 CH$_2$Cl$_2$, EtOAc, n-BuOT 및 $H_2O$로 분획하고 각종 column chromatography를 통하여 다수의 화합물을 분리하였다. 각 화합물은 이화학적 성상 및 spectral data로부터 scopoletin, esculetin dimethyl ether(scoparone), sterol mixture, $\beta$-sitosteryl-3-o-glucoside, kaempferol-3-o-glucoside, quercetin-3-o-glucoside, kaempferol-3-o-rutinoside로 확인하였으며 그 외 다수의 화합물은 그 구조를 규명중이다.

• 대한약침학회지
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• 제22권4호
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• pp.248-252
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• 2019

Objectives: The aim of the present work is evaluating the special effects of Urtica Dioica and Lamium Album on the serum level of K-Ras and GSK-3 beta in diabetic rats. Methods: In the present experimental study, 32 male Wistar rats randomly divided into 4 groups (Group I: normal control rats; receiving daily PBS, Group 2: diabetic control rats; receiving single dose of streptozotocin (60 mg/kg) and daily PBS, Group 3: Diabetic rats treated with 100 mg/kg of hydroalcoholic extract of the U. dioica, Group 4: Diabetic rats treated with 100 mg/kg of hydroalcoholic extract of L. Album. Diabetes-induced by an intraperitoneal injection of streptozotocin (60 mg/ kg). On the 14 th day of treatment, the weight, fasting blood sugar (FBS) and on 28 th day blood glucose, K-Ras and GSK3 beta was measured. Results: In diabetic group blood GSK- 3 beta increase in comparison to control group (P < 0.05), also blood K-Ras decrease in the diabetic group (P < 0.05). Both extracts reduced GSK-3 beta level, however, this reduction was only statistically significant by U.dioica (P < 0.05). Compared to diabetic group, blood K-Ras level increased by both extract (P < 0.05). Also diabetes induction increase blood glucose levels and both extracts decrease its level significantly (P < 0.05).there is no significant differences among both extract effects on blood glucose, and K-Ras. Conclusion: For the first time shown that both extracts by regulating GSK-3 beta and K-Ras improve blood glucose level. More studies are needed to determine all the effects of these herbs.

• 한국자원식물학회지
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• 제35권1호
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• pp.100-108
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• 2022

한반도 미기록 외래식물인 서양쐐기풀(쐐기풀과)를 한강 수계에서 발견하였다. 서양쐐기풀은 유럽, 온대 아시아, 서북아프리카 원산으로 알려져 있으며, 세계의 여러 지역에 도입되어 있는데 특히, 동아시아(일본), 오세아니아, 남아메리카에서 외래종으로 보고되었다. 본 분류군은 단성화이며, 자웅이주를 가지는 특징에 의해 근연분류군과 구분된다. Neighbor-Joining 계통수에서 국내 난지한강공원과 양재천에서 채집된 서양쐐기풀은 U. dioica s.s.군으로 유집되었다. 주요 형질에 대한 기재문과 화상자료 및 검색표를 제시하였다.

• 한국자원식물학회지
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• 제10권1호
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• pp.64-85
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• 1997

만덕봉(1,035.3m)은 동경 $128^{\circ}$54'24', 북위 $37^{\circ}$36'53'에 위치하며 행정적으로는 강원도 강릉시 강동면, 왕산면 및 옥계면의 경계에 자리하는 산으로 본 지역에 분포하는 유용자원식물상 및 식생에 관한 조사 결과를 보고하고자 한다. 유용자원식물상을 파악 하기 위해 1996년 4월과 9월 사이에 수집하여 분류 동정하였다. 또한 자원식물의 유용도는 각 식물의 용도에 따라 8개 항목으로 나누어 조사하였다. 식생의 특성을 파악하기 위해 Z-M방식에 의한 식물사회학적조사를 실시하여 군락표를 작성하였다. 본 지역에 자생하는 양치식물 이상의 관속식물자원은 97과 298속 406종 70변종 8품종으로, 총 484분류군이 분포하며, 이는 우리나라 관속식물자원의 11.9%에 해당하고 양치식물계수(Pte-Q)는 1.1이었다. 자원식물의 유용도는 식용자원이 46.7%, 목초용자원이 37.2%, 약용자원이 3.5.5% 등의 순으로 나타났고 용도를 알지 못하는 자원도 16.3%로 분포하였다. 한국특산식물은 키버들, 둥근왕팽나무, 누른종덩굴, 요강나물, 할미밀망, 털개살구, 둥근왕팽나무, 누른종덩굴, 요강나물, 할미밀망, 털개살구, 털조록싸리, 노랑갈퀴, 사울제비꽃, 지리강활, 참배암차즈기, 오동나무(재), 청괴불나무, 병꽃나무, 고려엉겅퀴 등 15분류군으로 우리나라 특산식물 570종류의 2.6%에 해당한다. 그 외 회귀식물로는 고비고사리, 애기쐐기풀, 솔나리, 연영초, 꽃창포, 암대극 등이 분포한다. 한석산의 식생은 1군목, 1군단, 1아군단, 4군락으로 분류되었다. 신갈나무-철쭉군목(꽤앵둥개-Quercetalia mongolicae Kim 1990) 신갈나무-생강나무군단(Lindero-Quercion mongolicae Kim 1990) A. 신갈나무 전형하위군락(Typical community) B. 굴참나무-신갈나무군락(Quercus variabilis-Quercus mongolica Community) 졸참나무-작살나무아군단 (Callicarpo-Quercenion serratae Kim 1990) C. 소나무-산거울군락 (Carex humilis v. nana - Pinus densiflora Community) D. 가래나무-가는잎쐐기풀군락 (Juglans mandshurica - Urtica angustifolia Community)

• 대한화장품학회지
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• 제40권1호
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• pp.45-54
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• 2014

각질형성세포주인 HaCaT세포에서 Lipopolysaccharide (LPS)로 유도하는 염증반응에는 tumor neurosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-1${\alpha}$ (IL-1${\alpha}$), interleukin-6 (IL-6), 및 interleukin-8 (IL-8)와 같은 염증 유발 사이토카인(pro-inflammatory cytokines)이 증가되고, 또한 염증반응을 매개하는 inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) 및 prostaglandins E2 (PGE2)도 증가된다. 본 연구에서는 이렇게 유도된 염증 반응에서 효과적으로 염증 관련인자를 조절할 수 있는 천연물을 발굴하고자 하였다. 그 결과, 마가목, 쐐기풀, 죽여 및 오배자 혼합 추출물이 IL-1${\alpha}$, TNF-${\alpha}$, IL-6 및 IL-8의 발현을 억제하고 COX-2, iNOS 및 PGE2의 발현도 억제함을 확인하였다. 아울러 IQ chamber$^{(R)}$을 이용하여 피부에 첩포할 때 sodium lauryl sulfate (SLS)로 유발한 피부자극에서 이들 혼합물이 효과적으로 그 자극을 억제함을 확인하였다. 따라서 본 연구 결과로부터 마가목, 쐐기풀, 죽여 및 오배자의 혼합물이 피부자극완화용 화장품 소재로서 민감성 피부 등을 위한 제품에 유용하게 사용될 수 있음을 확인하였다.

• 한국응용곤충학회지
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• 제32권1호
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• pp.61-67
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• 1993

점박이응애(Tetranychus urncae)의 알밀도(10~80), 공간분포〈집중 빛 균일분포) 및 서석면적크기 (3, 9, 16 $cm^2$)에 따른 긴털이리응애(Amblyseius longispinosus)의 가능반응을 연구하여 다음과 같은 결과를 얻었다. 긴털이리웅애의 점박이응애 발견효율은 밀도와 공간분포의 영향을 받았으나, 면적의 영향은 없었다. 포식량과 피식자간의 거리와는 매우 높은 역상관관계를 보였다(r=강.85; p=0.0001). 포식반응은 제2형의 기능반응을 보였다. 긴털이리응애의 기능반응은 random predator equation으로 잘 설명되었으며, 탐색률은 피식자의 집중분포하에서 반응면적에 따라 0.1030 - 0.1504였고 균일분포하에서는 0.0546~0.0276였다.

• 대한한의학회지
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• 제16권1호통권29호
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• pp.475-498
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• 1995

For the purpose of developing Korean Herbalogy with the plants of Urticaceae which grow wild and is planted in Korea, the these and writings on herbalogy, from literature of successive generations, have been thoroughly investigative and the results obtained were as follows: 1. There were totaled 11 genera and 44 species in Korea and among them medecinal plants are 9 genera, 19 species, some 43% in total but the number of species may be added because of similar plants. 2. According to the oriental name which can be used for medical purpose, the medicinal plants beloning to the Urticaceae were classified as Herba 10, Radix 8, Folium 3, Cortex 1, Flos 1, Rhizoma 1. Thus it was noticed that Herba was the main kind. 3. According to sum of 44 species in Urticaceae they were classified into Boehemeria genera 18, Urtica genera 9, Pliea genera 5, Elastosma genera 3, Parietaria genera 2, Pellionia genera 2, Achudemia 1, Debregeasia genera 1, Girardinia genera 1, Laportea genera 1, Nanocnide genera 1 etc. Thus it was noticed that Boehemeria genera was the main kind, some 41% in total. 4. According to nature and flavour of medicinal plants, they were classified into cold, cool; 6 each, wormth, heat; 4 each, balance 3. Thus it was noticed that cold and cool is the main in nature and flavour of medicinal plants. 5. According to the Properties and Principal Curative action, they were classified into, clearing up heat and toxin 9, drugs for urination an removing abscess 7, drugs for circulating blood and hemostasis 7, drugs for expelling wind 5, drugs for comporting embryo 4, 6. Comparing to whole medicinal plants 44 kinds, toxic durgs include minor toxin were 2 kinds, 5% of the whole. Thus toxic durgs were rare. From this result, It was revealed that the plants for medical purpose in Urticaceae was 43% kinds of the whole, in which Herba was mostly abundunt, toxic plants were so rare that it will be used for clinical treatments more easily. It is considered that many clinical experiments and approaches must be continued to use widely.