• Journal of Fashion Business
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• v.20 no.4
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• pp.128-140
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• 2016

In this study, dyeability of Urtica Dioica L. extract, which is relatively less studied, was measured. The extract of this plant was used to dye cellulose and protein fiber to check its usage as a natural green dye. Three different methods were used to produce extract. Dried Urtica Dioica L. was extracted with 100% ethanol, 50% ethanol with 50% distilled water and 100% distilled water. Then dyeing solution was obtained by blending with distilled water at 1-to-1 ratio. The maximum dyeability was obtained when 100% ethanol extract of dried Urtica Dioica L. used to dye fabrics at 60 degrees celsius for 60 minutes without mordant treatment. Cotton, rayon, wool and silk were dyed and dyeability for each fiber was measured for color difference value then compared to its control. The results show that dyeability of rayon and dyeability of wool are stronger, and that when color position for each mordant is measured, color difference is most diverse on cotton with pre-mordant treatment. Color fastness to wash, perspiration and rubbing crockmeter were superb, but color fastness to light was low, therefore, additional study on this is needed to improve. Urtica Dioica L. is now expected to be used practically as green color dye as well as medicinally and edible.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5317-5323
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• 2013

Breast cancer is the most prevalent cancer and one of the leading causes of death among women in the world. Plants and herbs may play an important role in complementary or alternative treatment. The aim of this study was to evaluate the antioxidant and anti-proliferative potential of Urtica dioica. The anti oxidant activity of an aqueous extract of Urtica dioica leaf was measured by MTT assay and the FRAP method while its anti-proliferative activity on the human breast cancer cell line (MCF-7) and fibroblasts isolated from foreskin tissue was evaluated using MTT assay. Mechanisms leading to apoptosis were also investigated at the molecular level by measuring the amount of anti and pro-apoptotic proteins and at the cellular level by studying DNA fragmentation and annexin V staining by flow cytometry. The aqueous extract of Urtica dioica showed antioxidant effects with a correlation coefficient of $r^2$=0.997. Dose-dependent and anti-proliferative effects of the extract were observed only on MCF-7 cells after 72 hrs with an $IC_{50}$ value of 2 mg/ml. This anti proliferative activity was associated with an increase of apoptosis as demonstrated by DNA fragmentation, the appearance of apoptotic cells in flow cytometry analysis and an increase of the amount of calpain 1, calpastatin, caspase 3, caspase 9, Bax and Bcl-2, all proteins involved in the apoptotic pathway. This is the first time such in vitro antiproliferative effect of aqueous extract of Urtica dioica leaf has been described for a breast cancer cell line. Our findings warrant further research on Urtica dioica as a potential chemotherapeutic agent for breast cancer.

• The Korean Journal of Mycology
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• v.45 no.2
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• pp.160-166
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• 2017

The genus Pseudoperonospora (Peronosporales, Oomycota) comprises six accepted species, including Ps. cubensis, which causes downy mildew on many economically important cucurbitaceous crops, and Ps. humuli, which occurs on hops. During a survey of downy mildew flora in Korea, a previously unreported species of Pseudoperonospora was found on Urtica angustifolia. Based on molecular phylogenetic and morphological analyses, the causal agent was identified as Pseudoperonospora urticae. This is the first report of Pseudoperonospora urticae occurring on Urtica angustifolia in Korea.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.04a
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• pp.168-168
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• 1996

가는잎쇄기풀(Urtica angustifolia Fisch.)은 쇄기풀과(Urticaceae)에 속하는 다년생 초본으로 중약 또는 민간에서 동속 근연식물과 함께 전초를 담마라하여 류마치스성 동통, 산후의 산풍, 소아의 추풍, 경풍,담마진의 치료에 사용되고 있다. Rat에서 실험적 항당뇨 효과를 검토해본 결과 혈당강하 작용이 있는 본 식물로부터 그 혈당강하 성분의 분리에 앞서 식물화학 성분을 규명하고자 본 실험에 착수하였다. 가는잎쇄기풀 전초의 MeOH ex.를 CH$_2$Cl$_2$, EtOAc, n-BuOT 및 $H_2O$로 분획하고 각종 column chromatography를 통하여 다수의 화합물을 분리하였다. 각 화합물은 이화학적 성상 및 spectral data로부터 scopoletin, esculetin dimethyl ether(scoparone), sterol mixture, $\beta$-sitosteryl-3-o-glucoside, kaempferol-3-o-glucoside, quercetin-3-o-glucoside, kaempferol-3-o-rutinoside로 확인하였으며 그 외 다수의 화합물은 그 구조를 규명중이다.

• Journal of Pharmacopuncture
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• v.22 no.4
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• pp.248-252
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• 2019

Objectives: The aim of the present work is evaluating the special effects of Urtica Dioica and Lamium Album on the serum level of K-Ras and GSK-3 beta in diabetic rats. Methods: In the present experimental study, 32 male Wistar rats randomly divided into 4 groups (Group I: normal control rats; receiving daily PBS, Group 2: diabetic control rats; receiving single dose of streptozotocin (60 mg/kg) and daily PBS, Group 3: Diabetic rats treated with 100 mg/kg of hydroalcoholic extract of the U. dioica, Group 4: Diabetic rats treated with 100 mg/kg of hydroalcoholic extract of L. Album. Diabetes-induced by an intraperitoneal injection of streptozotocin (60 mg/ kg). On the 14 th day of treatment, the weight, fasting blood sugar (FBS) and on 28 th day blood glucose, K-Ras and GSK3 beta was measured. Results: In diabetic group blood GSK- 3 beta increase in comparison to control group (P < 0.05), also blood K-Ras decrease in the diabetic group (P < 0.05). Both extracts reduced GSK-3 beta level, however, this reduction was only statistically significant by U.dioica (P < 0.05). Compared to diabetic group, blood K-Ras level increased by both extract (P < 0.05). Also diabetes induction increase blood glucose levels and both extracts decrease its level significantly (P < 0.05).there is no significant differences among both extract effects on blood glucose, and K-Ras. Conclusion: For the first time shown that both extracts by regulating GSK-3 beta and K-Ras improve blood glucose level. More studies are needed to determine all the effects of these herbs.

• Korean Journal of Plant Resources
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• v.35 no.1
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• pp.100-108
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• 2022

We found Urtica dioica L., an unrecorded alien plant, in the Han River basin of Korea. U. dioica is considered to be native to Europe, much of temperate Asia and western North Africa. This plant has been introduced to many other parts of the world. In Particularly, it reported as an invasive species from East Asia (Japan), Oceania and South America. This species is distinguished from related Korean taxa of the genus by its unisexual flower and dioecious plant species. In the Neighbor-Joining tree, U. dioica samples from the Han River Park (Sangam-dong, Mapo-gu, Seoul) and Yangjaecheon Stream (Daechi-dong, Gangnam-gu, Seoul) clustered into a clade consisting of a U. dioica s.s. Here, we provide a precise description, illustrations, a key to the related taxa, and photographs of its habitat.

• Korean Journal of Plant Resources
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• v.10 no.1
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• pp.64-85
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• 1997

This study was to establish the floristic composition and vegetation of resources vascular plants of Mt. Mandukbong(1,035.3 m; $128^{\circ}$54'24'E, $37^{\circ}$36'53'N). This work were investigated during the period of 1996. Resources vascular plants were composed of 97 families, 298 genera, 406 species, 70 varieties and 8 formae, Totaling 484 taxa. Among the investigated resources plants. 15 taxa(2.6%) were Korean endemic species. The forest were comparatively well conservated by Pteridophyta calculation(Pte-Q), 1.1 Useful of resources plants were Edible source(46.7%), Pasture source(37.2%), Medicinal source(35.5%), Ornamental source(12.1%)and Timber source(5.9%) respectively. The forest vegetion was classified into 1 order, 1 alliances, 1 suballiances and 4 communities; Rhododendro - Quercetalia mongolicae Kim 1990 Lindero - Quercion mongolicae Kim 1990 A. Typical community B. Quercus variablilis - Quercus mongolica Community Callicarpo - Quercenion serratae Kim 1990 C. Carex humilis v. nana - Pinus densiflora Community D. Juglans mandshurica - Urtica angustifloia community

• Journal of the Society of Cosmetic Scientists of Korea
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• v.40 no.1
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• pp.45-54
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• 2014

Lipopolysaccharide (LPS)-induced inflammatory responses in the HaCaT keratinocyte cell line produce proinflammatory cytokines, such as interleukin-1${\alpha}$(IL-1${\alpha}$), tumor neurosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-6 (IL-6), and interleukin- 8 (IL-8) and also increase the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandins E2 (PGE2). In this study, we developed new natural ingredients for cosmetics that inhibit the pro-inflammatory responses induced by LPS in HaCaT cells. The mixture of Sorbus commixta (SC), Urtica dioica (UD), Phyllostachys nigra (PN), and Rhus semialata gall (RS) extracts blocked the increase of TNF-${\alpha}$ IL-1${\alpha}$ IL-6, and IL-8. The increase of COX-2, iNOS, and PGE2 were also blocked by it. Finally, the mixture inhibited skin irritation induced by sodium lauryl sulfate (SLS), when applied on skin through IQ chamber$^{(R)}$. In conclusion, these results show that the mixture of SC, UD, PN, and RS can be used as a primary ingredient to alleviate skin irritation when cosmeceutical products are developed for sensitive skin.

• Korean journal of applied entomology
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• v.32 no.1
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• pp.61-67
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• 1993

Experiments were conducted to study the functional response of Amblyseius longispinosus Evans to egg densities (10-80) of Tetranychus urtica Koch under different egg distributions (clumped & uniform) and arena sizes (3, 9 & 16 $cm^2$). The searching success of A. longispinosus was affected by the spatial distribution and density of the prey but not by the arena size. there was a highly significant negative correlation (r=-0.85; p=0.0001) between predation amount and distances between preys. The predation response showed a type III functional response. The random predator equation satisfactorily described A. longispinosus predation. The search rate ranged from 0.1030 to 0.1504 under distribution of the prey while it ranged from 0.0546 to 0.276 under uniform distribution.

• The Journal of Korean Medicine
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• v.16 no.1 s.29
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• pp.475-498
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• 1995

For the purpose of developing Korean Herbalogy with the plants of Urticaceae which grow wild and is planted in Korea, the these and writings on herbalogy, from literature of successive generations, have been thoroughly investigative and the results obtained were as follows: 1. There were totaled 11 genera and 44 species in Korea and among them medecinal plants are 9 genera, 19 species, some 43% in total but the number of species may be added because of similar plants. 2. According to the oriental name which can be used for medical purpose, the medicinal plants beloning to the Urticaceae were classified as Herba 10, Radix 8, Folium 3, Cortex 1, Flos 1, Rhizoma 1. Thus it was noticed that Herba was the main kind. 3. According to sum of 44 species in Urticaceae they were classified into Boehemeria genera 18, Urtica genera 9, Pliea genera 5, Elastosma genera 3, Parietaria genera 2, Pellionia genera 2, Achudemia 1, Debregeasia genera 1, Girardinia genera 1, Laportea genera 1, Nanocnide genera 1 etc. Thus it was noticed that Boehemeria genera was the main kind, some 41% in total. 4. According to nature and flavour of medicinal plants, they were classified into cold, cool; 6 each, wormth, heat; 4 each, balance 3. Thus it was noticed that cold and cool is the main in nature and flavour of medicinal plants. 5. According to the Properties and Principal Curative action, they were classified into, clearing up heat and toxin 9, drugs for urination an removing abscess 7, drugs for circulating blood and hemostasis 7, drugs for expelling wind 5, drugs for comporting embryo 4, 6. Comparing to whole medicinal plants 44 kinds, toxic durgs include minor toxin were 2 kinds, 5% of the whole. Thus toxic durgs were rare. From this result, It was revealed that the plants for medical purpose in Urticaceae was 43% kinds of the whole, in which Herba was mostly abundunt, toxic plants were so rare that it will be used for clinical treatments more easily. It is considered that many clinical experiments and approaches must be continued to use widely.