• Transactions on Electrical and Electronic Materials
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• 제3권4호
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• pp.21-26
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• 2002

Color correction methods of chromaticity coordinates using Color Matching Function (CMF) were studied to develop a device-independent portable-type urine analyzer. The reflection spectra were measured for the degrees of 10 test items of the urine reagent strip (urine strip) to develop a portable-type urine analyzer. A computer simulation was performed to quantitatively distinguish the color reactions of the urine system, by using the spectral power distribution of Light Emitting Diode(LED), the reflection of a urine strip, and spectral sensitivity of a photodiode. To develop a device-independent system, chromaticity coordinates were modified to reduce the color deviations in the urine strip, by using the temperature compensation of LED and the color transformation by CMF. The experimental values obtained by developed urine system exhibited the accuracy above 95% for all color samples.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2001년도 추계학술대회 논문집
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• pp.320-323
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• 2001

A computer simulation was performed to distinguish quantitatively a color reaction in a urine analysis systems by using the spectral power distribution of LEDs, the spectral reflectance of a urine strip, and the spectral sensitivity of photodiode. The CIE tristimulus values and CIE chromaticity coordinates ware modified to be conformable with real color reactions in a urine strips. Results on color simulation showed a of real color in comparison with those obtained by Colorimeter CM2C(Color Savvy).

• Childhood Kidney Diseases
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• 제17권2호
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• pp.29-34
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• 2013

Urine production is vital for the removal of certain waste products produced by metabolism in the body and for the maintenance of homeostasis in the body. The kidneys produce urine by the following three precisely regulated processes: filtration, reabsorption, and secretion. Urine is composed of water, certain electrolytes, and various waste products that are filtered out of the blood through the glomeruli. The physical features of urine are evaluated carefully to detect any abnormal findings that may indicate underlying diseases in the genitourinary system. A change in urine color may indicate an underlying pathological condition, although many of the causes of abnormal urine color are benign effects of medications and foods. A characteristic and specific odor may be the result of a metabolic disease rather than a concentrated specimen or a simple urinary tract infection. Although transient changes in urine output and nocturia are usually benign conditions, persistent abnormal findings require further workup, with a thorough medical history taking. This article presents many of the conditions that physicians may encounter and will help them in the diagnosis and in establishing a treatment plan.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2001년도 추계학술대회 논문집 Vol.14 No.1
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• pp.320-323
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• 2001

A computer simulation was performed to distinguish quantitatively a color reaction in a urine analysis systems by using the spectral power distribution of LEDs. the spectral reflectance of a urine strip. and the spectral sensitivity of photodiode. The CIE tristimulus values and CIE chromaticity coordinates ware modified to be conformable with real color reactions in a urine strips. Results on color simulation showed a of real color in comparison with those obtained by Colorimeter CM2C(Color Savvy).

• 대한의용생체공학회:의공학회지
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• 제8권2호
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• pp.145-150
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• 1987

Urine NMR analyses made by use of an 80 MHz proton NMR spectrometer show that aromatic proton NMR signals appear in most censer patients'urine. On the assumption that the signals may be caused by the phenolic compound of tyrosine excreted in the urine, a jellied reagent is used for identifying them by observing the urine color reaction. It is observed that the reagent reacted to the cancer urine becomes red. Such a change of the urine color seems to indicate the substance of tyrosine. Recently an attempt to determine the reagent sensitivity an specificity of the urine of 69 persons including cancer and noncancer patients has been made. The results of the attempt are respectively 85.3% for sensitivity and 91.4% for specificity. This seems to show a possibility that the reagent can be used for the diagnosis.

• Archives of Pharmacal Research
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• 제11권2호
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• pp.134-138
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• 1988

Urine measurements by MNR were made for 25 persons including cancer and non-cancer patients. The aromatic proton signals of NMR wer observed much more often in cancer patients' urine than non-cancer patients' one. To compare the amount of the phenolic compounds excreted in urine between cancer and non-cancer patient, urine analysis by HPLC with UV detector was performed. Total peak area and major peak areas of cancer patients' urine wer emuch greater than those of non-cancer patients' one. To check the phenolic compound excreted in urine, a new jellied reagent named Gift reagent which was based on Millon's reagent, was developed for urine color reaction. When the reagent was tested, the sensitivity and specificity for urine samples of 69 persons including cancer and non-cancer patients were measured by 85.3% and 91.4%, respectively, indicating that the Gift reagent afford a possibility of cancer diagnosis.

• 한국지능시스템학회논문지
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• 제17권7호
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• pp.919-923
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• 2007

본 논문에서는 스트립의 컬러영상을 이용한 요 분석기의 개발을 제안하였다. 제안된 분석기에서 스트립의 컬러영상획득을 위해 이미지센서를 이용하였으며, 상이한 요성분에 반응하는 독립된 각 패드들의 영상을 한 번에 촬영하고, 촬영된 패드컬러를 분석하여 요성분의 측정값을 출력하는 특징을 가지도록 하였다. 특히 개발된 장치는 11개의 요 성분을 측정 분석하는 장치로 프로세서에 의하여 측정된 색상을 처리함으로써 복잡한 과정을 없앨 수 있어 빠른 동작과 가벼우며, 소형화되고, 가시적 판단 때보다 정확성을 매우 높일 수 있었다. 또한 유 무선의 통신인터페이스에 의하여 다른 검사기능을 가진 외부장비나 개인용 컴퓨터 및 의료기관이나 기타 요구하는 다른 곳으로 전송이 가능하도록 하였다.

• 대한의용생체공학회:의공학회지
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• 제24권3호
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• pp.183-192
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• 2003

본 연구에서는 구현된 요분석 시스템으로 획득한 데이터를 보정하기 위하여 색 좌표 변환 기법을 제안하였다. 일반적으로 요분석 시스템은 요분석용 스트립의 정색반응을 검출하는 과정에서 여러 가지 비선형적인 특성 즉 광 모듈의 메커니즘, 하드웨어, 그리고 주변 환경에 의해 색 왜곡된 입·출력 특성을 지닌다 따라서 보다 높은 정확도와 재현성을 유지하기 위해 장비 특성화 기법을 도입하여 색 왜곡 현상을 보정하였다. 본 연구에서는 명암 보정, ,3차 스플라인 보간법에 의한 RGB 신호의 특성 곡선 추출, 기준색 고정 선형변환 기법을 사용하여 색 보정 과정을 수행하였다 색 보정을 위해 사용된 표준 장비는 1931년 CIE XYZ 색공간 특성을 지닌 좌표계로 설정하였으며, 동일한 칼라 샘플에 대해 요분석 시스템의 출력값과 표준 장비의 출력값이 일치되도록 하는 보정 행렬을 구하였다. 구현된 요분석 시스템을 색 보정한 후 기준 데이터와 비교한 결과 양호한 색상 정확도를 나타내었다 요분석용 스트립의 10 가지 항목에 대해 구현된 두 대의 요분석 시스템을 사용하여 실험한 결과 장비간 색차는 1.28이었다.

• 한국정보전자통신기술학회논문지
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• 제2권2호
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• pp.9-14
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• 2009

본 연구에서는 유헬스용 요분석기를 개발하기 위한 선행 연구로서 요분석 스트립의 색변화를 측정할 수 있는 정색반응 전자회로를 개발하였다. 정색반응 시스템은 컴퓨터, 정색반응 전자회로, 트레이장치, 센서조합체 및 소프트웨어로 구성하였다. 요분석 스트립의 색 변화를 측정하기 위하여 칼라센서가 사용되기 때문에, 표준 색상지를 이용하여 칼라센서의 측정값과 RGB값 사이의 선형방정식을 수립하였다. 빨간색(R)의 회귀방정식은 $Red=0.2414{\times}x$(센서 값) - 3.0042($R^2=0.9801$)로 나타났고, 녹색(G)의 회귀방정식은 $Green=0.2857{\times}x$(센서 값) - 6.4251($R^2=0.9868$)로 나타났고, 파란색(B)의 회귀방정식은 $Blue=0.2114{\times}x$(센서 값) - 6.2743($R^2=0.9837$)으로 나타났으므로 표준색상지와 칼라센서는 높은 상관관계가 있는 것을 알 수가 있었다. 정색반응 시스템을 검증하기 위하여 요 성분 중 적혈구, 빌리루빈, 우로빌리노겐, 케톤, 단백질의 5가지 성분에 대하여 각기 다른 농도로 표준시약을 제조하여 정색반응을 측정하였다. 각 시약의 농도에 따른 칼라센서의 정색반응 결과가 통계적으로 타당한 결과를 보였고 유헬스용 요분석기 개발에 적용할 수 있을 것으로 사료된다.

• 사상체질의학회지
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• 제20권2호
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• pp.129-134
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• 2008

1. Objectives The primary purpose of this case study is to report that a Soeumin Mang-yang Syndrome with redness of urine and urination difficulty was treated with 'Soeumin Seungyangikgibuja-tang(升陽益氣附子湯)(SIBT)' and then his symptoms, laboratory test(urine) and urine color improved. 2. Methods The patient has the symptoms including redness of urine, discomfort after urinating, general body sweating, constipation and thirst. We diagnosed him as Soeumin Mang-yang Syndrome. So we treated him with 'SIBT(升陽益氣附子湯)'. 3. Results and Conclusions After the constitutional treatment with SIBT(升陽益氣附子湯) on Soeumin Mang-yang Syndrome patient, his symptoms and laboratory test(urine) improved and urine color was clear. 'SBIT(升陽益氣附子湯)' is considered to be effective in Soeumin Mang-yang Syndrome. The change of urine color can be good evidence for the symtoms of Mang-yang Syndrome is improved.