• Title/Summary/Keyword: Uptake rate

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Study of Simultaneous Counting of Thyroid Uptake with Quantitative Analysis of Thyroid Scans (갑상샘 스캔 정량분석을 통한 갑상샘 섭취율 동시계측법 연구)

  • Jung-Soo Kim;Geun-Woo Kim
    • Journal of radiological science and technology
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    • v.46 no.5
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    • pp.401-408
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    • 2023
  • Thyroid uptake measurements can be subject to measurement errors due to the scoping and positioning of the thyroid gland. To compensate for these limitations, the clinical utility of the thyroid simultaneous counting method as an alternative to thyroid uptake measurement was analyzed and evaluated experimentally through quantitative analysis of images acquired after thyroid scanning. Experimental data were obtained using a Gamma camera (GE infinia), a thyroid uptake system (KOROID 1), and a thyroid neck phantom. Based on the thyroid uptake rate of 1-5% according to the protocol of thyroid scan test (99mTcO4 - , 370 MBq) in normal results, 99mTcO4 - was set in the range of 3.7-18.5 MBq (Matrix: 256×256, Scan time: 1 min, collimator: pin hole, phantom-collimator distances: 7 cm). The acquired images were corrected for the attenuation of isotopes due to the set-up time and half-life by applying the Auto Region of interest (ROI) drawing system, and the significance of the experimental results was evaluated by Multiple linear regression analysis (SPSS, ver. 22, IBM). The thyroid uptake rate showed a significant correlation between the dose and the measured counts when using the thyroid uptake system equipment. Meanwhile, the quantitative analysis counts of phantom images using Gamma camera also showed a significant correlation. Thus confirmed that the correlation between these two experiments was statistically significant (P<0.05). The simultaneous counting protocol, which indirectly measures thyroid uptake from thyroid scans, is likely to be clinically relevant if complemented by additional studies with different variables in patients with thyroid disease.

Incorporation of Tobacco Chloroplasts into Soybean Protoplasts (콩 원형질체내로의 담배 엽록체 이입)

  • 차현철
    • Journal of Plant Biology
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    • v.25 no.4
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    • pp.181-188
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    • 1982
  • Chloroplasts isolated from tobacco (Nicotiana tabacum L. cv. Virginia 115) leaves have been transferred into protoplasts of soybean (Glycine max Merr. cv. Jangyeop) suspension-cultured cells with the help of polyethylene glycol (PEG). The increased yield in protoplasts of chloroplast uptake was depended upon the concentration of both PEG 4,000 and PEG 6,000. The highest yield(36%) occurred at 50% of both PEG, and the yield was decreased above this concentration. The rate of uptake with the incubation time was highest at one hour, then decreased. The process of the chloroplast uptake into the protoplasts was similar with that of a protoplast fusion, except forming invagination during uptake.

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Dyeing of Cotton with Rosemary Extract (로즈마리 추출물틀 이용한 면의 염색)

  • 신윤숙;오유정
    • Journal of the Korean Society of Clothing and Textiles
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    • v.26 no.3_4
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    • pp.485-491
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    • 2002
  • Dyeing properties of rosemary colorants on cotton fabrics were investigated. Effect of dyeing conditions on dye uptake and effect of mordanting and cationizing on dye uptake, color change and colorfastness were explored. Also, antimicrobial activity of rosemary colorants was ascertained and further effect of cationizing on antimicrobial activity was investigated. Affinity of rosemary colorants to cotton fiber was considerably low, and its isotherm adsorption curve was Freundlich type, indicating that hydrogen bonding was involved in the adsorption of rosemary colorants to cotton fiber. The cotton fabrics showed generally high colorfastness except fastness to washing and light. The cationized cotton with Cationon UK(quarterly ammonium salt) showed higher dye uptake and shorter dyeing time, compared with the untreated cotton. The cationized cotton showed good colorfastness to washing, perspiration and rubbing. Antimicrobial activity of rosemary colorfastness was confirmed. The cationized cotton itself showed high bacterial reduction rate. For cationized and dyed samples, as dye uptake increased, bacterial reduction rate was decreased slightly.

Biological Toxicity Evaluation of Heavy Metal using Oxygen Uptake Rate on Activated Sludge Process (호흡율 측정에 의한 활성슬러지의 중금속 생물독성평가)

  • Ahn, Woo Jung;Baek, Seung-Kyu
    • Journal of Korean Society of Water and Wastewater
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    • v.21 no.3
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    • pp.279-285
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    • 2007
  • Toxicity evaluations using oxygen uptake rate (OUR) on activated sludge process were investigated. On toxicity evaluations of heavy metals, all toxicants in experiments decreased OUR with respect to the concentrations of the toxicants, while high toxicities with cyanide and mercury were observed respectively. On toxicity evaluations of composite heavy metals, composite toxicities had similar results as to the total sum of each toxicants that presents accurate toxicity evaluation using OUR. From these results, it is concluded that activated sludge is effective indicator for toxicity evaluation on wastewater of biological treatment plants.

Improvement of bacteria for removing of phosphate by spheroplast fusion (원형질체 융합에 의한 인산염 제거균주의 개량)

  • 윤성녀;조경주;조홍범;최영길
    • Korean Journal of Microbiology
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    • v.29 no.2
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    • pp.117-122
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    • 1991
  • In order to improve the removal ability of phosphate, Spheroplast fusions were performed among auxotrophic mutants of Aeromonas hydrophila isolated from waste water, named A13 and A14, Aci37 auxotrophic mutant of Acinetobactercalcoaceticus, and auxotrophic E. coli HR262/pCE27 carring pit gene. Eight fusants obtained from this experiment showed different biochemical characteristics. When the rate of phosphate uptake among fusants (F1-F8) was investigated in Phosphate Uptake Medium (PUM), F8 strain showed the highest rate for phosphate removal, 7 times as much as control after two hours incubation. The role of cations ($Mg^{++}$ ,$Ca^{++}$ , $K^{+}$ in phosphate uptade by F8 was also investigated in PUM without each salt. $K^{+}$ seemed to be crucial. Being compared with phosphate untake rate in PUM, that in PUM without $K^{+}$ was reduced 1.5 times. Therefore, by applying F8 strain and $K^{+}$ in practical environmental system, the increased efficiency in phosphate removal can be derived.

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Influence of Body Size and Ambient Temperature on the Uptake Rate of Cd, Se, and Zn in the California Mussel, Mytilus californianus (개체 크기와 온도가 홍합(Mytilus californianus)의 금속 흡수율에 미치는 영향)

  • Lee Jung-Suk;Lee Byeong-Gweon;Lee In-Tae
    • Korean Journal of Environmental Biology
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    • v.22 no.3
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    • pp.438-445
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    • 2004
  • A radiotracer study was conducted to evaluate the influence of body size and temperature on the uptake rates of Cd, Se and Zn in the California mussel, Mytilus californianus. Uptake rates of Cd, Se and Zn were determined simultaneously with clearance of the mussels with 3 different size classes (0.07, 0.24 and 0.73 g flesh dry weight $individual^{-1})$ and at 4 different temperatures (3, 8, 13 and $21^\circ{C})$. The weight-specific uptake rates of 3 elements significantly decreased with body size, but increased with temperature. Simultaneously measured clearance rates of mussels were closely associated with metal uptake rates. The significant association of clearance rates and metal uptake rates of mussels emphasizes the importance of functional role of water pumping activity in the metal uptake process in filter-feeding organisms.

A Research on Superparamagnetic Iron Oxide Nanoparticles' Toxicity to U373MG Cell and its Effect on the Radiation Survival Curve (산화철 나노입자의 U373MG 세포 독성평가 및 방사선 세포생존 곡선에 미치는 영향에 대한 연구)

  • Kang, Seonghee;Kim, Jeonghwan;Kim, Dokyung;Kang, Bosun
    • Journal of the Korean Society of Radiology
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    • v.6 no.6
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    • pp.507-513
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    • 2012
  • This research was performed to evaluate the superparamagnetic iron oxide nanoparticles'(SPIONs) cell toxicity and to measure the radiation cell survival curve changes of SPIONs-uptake glioblastoma multiforme cells. The results could be practically used as the fundamental data to ameliorate proton beam cancer therapy, for example, providing necessary GBM treatment dose in the proton beam therapy when the therapy takes advantage of SPIONs. The assessment of the toxicological evaluation of synthesized SPIONs was accomplished by MTT assay as an in vitro experiment. The results showed no meaningful differences in the cell survival rate at the $1-100{\mu}g/ml$ SPIONs concentrations, but the cell toxicity was shown as the cell survival rate decreased up to 74.2% at the $200{\mu}g/ml$ SPIONs concentration. Then, we measured each radiation cell survival curve for U373MG cells and SPIONs-uptake U373MG cells with 0~5 Gy of proton beam irradiations. It is learned from the analysis of the experimental results that the SPION-uptake cells' radiation survival rate was more rapidly decreased as the irradiation dose increased. In conclusion we confirmed that SPIONs-uptake in U373MG cells induces cell death at the much less dose than the lethal dose of SPION-non-uptake cell. This research shows that the therapeutic efficacy of glioblastoma multiforme treatment in proton beam therapy can be improved by SPIONs targeting to the GBM cells.

Dyeing properties of cotton fabric with pomegranate colorants and antimicrobial properties (석류색소의 면섬유에 대한 염색성과 항균성)

  • 신윤숙;조은경
    • Journal of the Korean Society of Clothing and Textiles
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    • v.25 no.3
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    • pp.577-585
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    • 2001
  • Dyeing properties of the colorants extracted from pomegranate hull on cotton fabric were investigated. Effects of dyeing conditions and mordanting on dye uptake, color change and colorfastness were explored. Cationic agent treatment was done for cotton to improve low dyeability in natural dyeing. In addition antimicrobial activity of the cotton fabrics dyed with pomegranate colorants was examined by the shake flask method. Pomegranate colorants showed low affinity to cotton fiber and its adsorption isotherm was Freundlich type. Therefore, hydrogen bonding was involved in the adsorption of pomegranate colorants onto cotton fiber. Mordants did not significantly increase dye adsorption. Pomegranate colorants produced mainly yellow color on cotton fabric. In order to improve dye uptake, cotton was cationized by treating with Cationon UK(quarterly ammonium salt) and chitosan. The cationized cotton with Cationon UK showed higher dye uptake and shorter dyeing time, compared with the untreated cotton. Chitosan treated cotton also showed high dye uptake, but chitosan was less effective compared with Cationon UK. Fastness to washing, perspiration, and rubbing was not improved by mordanting and cationizing treatment, but light fastness was increased by all mordants and cationic agent. As dye concentration increased, bacterial reduction rate was increased and mordants did not significantly increase bacterial reduction rate.

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Effects of the ectomycorrhizal fungus Pisolithus tinctorius and Cd on physiological properties and Cd uptake by hybrid poplar Populus alba × glandulosa

  • Han, Sim-Hee;Kim, Du-Hyun;Lee, Jae-Cheon
    • Journal of Ecology and Environment
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    • v.34 no.4
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    • pp.393-400
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    • 2011
  • The effects of the ectomycorrhizal fungus Pisolithus tinctorius and cadmium (Cd) on physiological properties and Cd uptake by Populus alba ${\times}$ glandulosa was investigated under greenhouse conditions. Cd treatment decreased the photosynthetic rate ($P_N$) of both non-mycorrhizal (NM) plants (16.3%) and ectomycorrhizal (ECM) plants (11.5%). In addition, the reduction in total dry weight by Cd treatment was greater in ECM plants (24.3%) than that in NM plants (17.6%). Mycorrhizal infection increased the $P_N$ and transpiration rate in both control and Cd-treated plants. Cd treatment increased superoxide dismutase (SOD) activity and decreased glutathione reductase activity, and the increase of SOD activity by Cd treatment was greater in NM plants (40.3%) than that in ECM plants (3.7%). Thiol content increased in both NM and ECM plants treated with Cd solution, and the increase in thiol content in NM plants (43.9%) was greater than that of ECM plants (15.6%). Cd uptake in the leaves, stems, and roots of ECM plants was 69.9%, 167.2% and 72.8%, respectively, higher than in the NM plants. However, the increase in Cd uptake ability of ECM plants resulted in a reduction in dry weight.

Bran Structure and Water Uptake Rate of Japonica and Tongil-type Brown Rices (일반계와 통일계 현미의 겨층구조와 수분 흡수 속도)

  • Lee, Soo-Jeung;Kim, Sung-Kon
    • Applied Biological Chemistry
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    • v.37 no.2
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    • pp.94-99
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    • 1994
  • Bran structure and water uptake rate for brown rices of thirteen japonica and twelve Tongil cultivars were investigated. The japonica type was shorter in length and had lower value in the ratio of length to width than Tongil one. No differences were observed in width and weight between the two types. The number of aleurone layer and the thickness of bran layer were higher in dorsal side than in ventral side in all rice cultivars. The structure in ventral side was similar but the number of aleurone layer in dosal side was higher in japonica samples. There were no significant differences in water uptake rates showed no correlation with the bran structure.

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