• 제목/요약/키워드: Upper limit of normal

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가미 태음조위탕 복용이 간기능에 미치는 영향 : 전향적 단일기관 예비연구 (Influence of Prescribed Gamitaeeumjowi-tang on Liver Function : Prospective Single-center Pilot Study)

  • 진용희;김강식;한인엽;이현배
    • 한방비만학회지
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    • 제10권1호
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    • pp.29-40
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    • 2010
  • Objective The aim of this study was to evaluate the influence of Gamitaeeumjowi-tang(GTT) prescribed by doctors of korean(KMD) medicine on liver function. Methods For this single-center, prospective, observational study, we enrolled patients who wished to take GTT prescribed by KMD for losing weight. sixty(60) patients took GTT for 33.8 days and completed questionnaires. Liver function tests(LFTs) were performed bofore(first test) and after each GTT treatment(finish test). For LFT, T-bil, ALP, AST, ALT were measured. Result There were no significant changes in LFT data between the first and finish tests. At first test, levels of test seven(7) patients were more than twice of normal range of upper limit, levels of eight(8) patients were more than normal range of upper limit, less than twice of normal range of upper limit. At last test, levels of nine(9) patients were more than normal range of upper limit, less than twice of normal range of upper limit. Conclusion The current study showed that ingestion of GTT prescribed by KMD did not increase the frequency of abnormal LFTs, at least in the short term.

INTERPRETING A SINGLE ANTISTREPTOLYSIN O TEST: A COMPARISON OF THE 'UPPER LIMIT OF NORMAL' AND LIKELIHOOD RATIO METHODS

  • Gray Gregory C.;Struewing Jeffery P.;Hyams Kenneth C.;Escamilla Joel;Tupponce Alan K.;Kaplan Edward L.
    • 대한예방의학회:학술대회논문집
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    • 대한예방의학회 1994년도 교수 연수회(역학)
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    • pp.164-168
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    • 1994
  • Single serologic tests may occasionally influence clinicians in making diagnoses. The antistreptolysin O (ASO) test is a frequently used tool for detecting recent Streptococcus pyogenes infection and is helpful in the diagnosis of diseases like rheumatic fever. Using data from a 1989 prospective study of 600 healthy male military recruits, in which 43% experienced S. pyogenes upper respiratory tract infection (2-dilution rise in ASO), this report compared two methods of interpreting a single ASO titer. Using the 'upper limit of normal' (80 percentile) method, recruits with an ASO titer of greater than 400 showed evidence of recent S. pyogenes infection. This method had a sensitivity and specificity of only 65.9 and 81.9% respectively. In contrast to the 'yes-no'. dichotomy of the 'upper limit of normal' method. the likelihood ratio method statistics were ASO value specific, more consistent with clinical judgment, and better emphasized the caution clinicians must use in interpreting a single ASO test.

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수질오염총량관리를 위한 환경기초시설 배출수질의 통계적 평가방법 개선 : 선형보간법의 백분위수방법 (Implementation of the Calculation Method for 95% Upper Limit of Effluent Water Quality of Sewage Treatment Plant for Total Maximum Daily Loads : Percentile Ranking Method)

  • 박재홍;김동우;오승영;류덕희;정동일
    • 한국물환경학회지
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    • 제24권6호
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    • pp.676-681
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    • 2008
  • The evaluation of the effluent water quality of sewage treatment plant is one of the most important factor in calculating total maximum daily loads (TMDLs). Current method to calculate 95% upper limit of effluent water quality of sewage treatment plant assuming normal distribution of data needs to be implemented in case of non-normal distribution. We have investigated the applicability of percentile ranking method as a non-parametric statistical analysis in case of non-normal distribution of data.

Variable Sampling Inspection with Screening When Lot Quality Follows Mixed Normal Distribution

  • Suzuki, Yuichiro;Takemoto, Yasuhiko;Arizono, Ikuo
    • Industrial Engineering and Management Systems
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    • 제8권3호
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    • pp.131-138
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    • 2009
  • The variable sampling inspection scheme with screening for the purpose of assuring the upper limit of maximum expected surplus loss after inspection has been proposed. In this inspection scheme, it has been assumed that a product lot consists of products manufactured through a single production line and lot quality characteristics follow a normal distribution. In the previous literature with respect to inspection schemes, it has been commonly assumed that lot quality characteristics obey a single normal distribution under the condition that all products are manufactured in the same condition. On the other hand, the production line is designed in order that the workload of respective processes becomes uniform from the viewpoint of line balancing. One of the solutions for the bottleneck process is to arrange the workshops in parallel. The lot quality characteristics from such a production line with the process consisting of some parallel workshops might not follow strictly the single normal distribution. Therefore, we expand an applicable scope of the above mentioned variable sampling inspection scheme with screening in this article. Concretely, we consider the variable sampling inspection with screening for the purpose of assuring the upper limit of average outgoing surplus quality loss in the production lots when the lot quality follows the mixed normal distribution.

한국인혈압(韓國人血壓)의 정상치역(正常値域) (Normal Range of Blood Pressure of Korean)

  • 김인달;안윤옥;조수헌
    • Journal of Preventive Medicine and Public Health
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    • 제7권2호
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    • pp.395-401
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    • 1974
  • In order to figure out the normal range, lower limit of hypertension and upper limit of hypotension of the blood pressure of Korean, authors had measured blood pressure according to Korotkow's method for 31,897 healthy persons as samples who were occupied different levels of the social class except cases who would seem to be the essential hypertension and had the diseases affecting to secondary hypertension. A following conclusion was induced by actual measurement and statistical reasoning. 1. The normal range and limits of hypo- and hypertension by sex and age groups of Korean were demonstrated in Table 1 and Figure 1. 2. The more aging the higher value of blood pressure in both sexes, especially women rather than men and systolic as to diastolic. 3. Generally, blood pressure values of female were lower than male, after 55 years of age, however, the crossing phenomenon was recognizable. 4. To settle the normal and abnormal ranges of the blood pressure of Korean, it was attempted that $M{\pm}1.282{\sigma}$ as normal range, $M+2{\sigma}$ as lower limit of hypertension and $M-2{\sigma}$ as upper limit of hypotension were calculated, and regression lines were drawn to adjust the biological variables and derive continuity from each age class. (Fig. 2 and 3) 5. The blood pressure levels were becoming elevated as to getting increased of the body weight, particularly diastolic value at 40-49 age group in male and systolic value at 30-39 age group in female.

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Droplet size prediction model based on the upper limit log-normal distribution function in venturi scrubber

  • Lee, Sang Won;No, Hee Cheon
    • Nuclear Engineering and Technology
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    • 제51권5호
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    • pp.1261-1271
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    • 2019
  • Droplet size and distribution are important parameters determining venturi scrubber performance. In this paper, we proposed physical models for a maximum stable droplet size prediction and upper limit log-normal (ULLN) distribution parameters. For the proposed maximum stable droplet size prediction model, a Eulerian-Lagrangian framework and a Reitz-Diwakar breakup model are solved simultaneously using CFD calculations to reflect the effect of multistage breakup and droplet acceleration. Then, two ULLN distribution parameters are suggested through best fitting the previously published experimental data. Results show that the proposed approach provides better predictions of maximum stable droplet diameter and Sauter mean diameter compared to existing simple empirical correlations including Boll, Nukiyama and Tanasawa. For more practical purpose, we developed the simple, one dimensional (1-D) calculation of Sauter mean diameter.

제사위전위증유우에 있어서 몇가지 혈청전해질 농도에 관한 조사연구 (Changes in Selected Electrolyte Concentrations in Dairy Cowe with Abomasal Displacement)

  • 이사균;정창국
    • 한국임상수의학회지
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    • 제2권1호
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    • pp.143-150
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    • 1985
  • The concentrations of serum calcium, inorganic phosphorus, sodium and potassium from 24 cows with left displacement of abomasum and 21 cows with right displacement of abomasum on pre and postoperation were determined. 1. The preoperative levels of serum calcium in left and right displacement of abomasum were below normal and returned to normal levels postoperatively. 2. The preoperative levels of serum inorganic phosphorus in left and right displacement of abomasum showed slight increase preoperatively and consistent slight rise postoperatively. 3. The preoperative levels of serum sodium in left and right displacement of abomasum were slightly below normal and maintained low levels postoperatively. 4. The preoperative levels of serum patassium in left and right displacement of abomasum were low normal limit and increased to upper normal limit postoperatively.

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An alternative approach to extreme value analysis for design purposes

  • Bardsley, Earl
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2016년도 학술발표회
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    • pp.201-201
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    • 2016
  • The asymptotic extreme value distributions of maxima are a natural choice when designing against future extreme events like flood peaks or wave heights, given a stationary time series. The generalized extreme value distribution (GEV) is often utilised in this context because it is seen as a convenient single expression for extreme event analysis. However, the GEV has a drawback because the location of the distribution bound relative to the data is a discontinuous function of the GEV shape parameter. That is, for annual maxima approximated by the Gumbel distribution, the data is also consistent with a GEV distribution with an upper bound (no lower bound) or a GEV distribution with a lower bound (no upper bound). A more consistent single extreme value expression for design purposes is proposed as the Weibull distribution of smallest extremes, as applied to transformed annual maxima. The Weibull distribution limit holds here for sufficiently large sample sizes, irrespective of the extreme value domain of attraction applicable to the untransformed maxima. The Gumbel, Type 2, and Type 3 extreme value distributions thus become redundant, together with the GEV, because in reality there is only a single asymptotic extreme value distribution required for design purposes - the Weibull distribution of minima as applied to transformed maxima. An illustrative synthetic example is given showing transformed maxima from the normal distribution approaching the Weibull limit much faster than the untransformed sample maxima approach the normal distribution Gumbel limit. Some New Zealand examples are given with the Weibull distribution being applied to reciprocal transformations of annual flood maxima, where the untransformed maxima follow apparently different extreme value distributions.

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Discretization technique for stability analysis of complex slopes

  • Hou, Chaoqun;Zhang, Tingting;Sun, Zhibin;Dias, Daniel;Li, Jianfei
    • Geomechanics and Engineering
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    • 제17권3호
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    • pp.227-236
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    • 2019
  • In practice, the natural slopes are frequently with soils of spatial properties and irregular features. The traditional limit analysis method meets an inherent difficulty to deal with the stability problem for such slopes due to the normal condition in the associated flow rule. To overcome the problem, a novel technique based on the upper bound limit analysis, which is called the discretization technique, is employed for the stability evaluation of complex slopes. In this paper, the discretization mechanism for complex slopes was presented, and the safety factors of several examples were calculated. The good agreement between the discretization-based and previous results shows the accuracy of the proposed mechanism, proving that it can be an alternative and reliable approach for complex slope stability analysis.

CA 19-9 방사면역측정법의 기본적 검토 및 악성종양환자에서의 혈청 CA 19-9치의 임상적 의의에 관한 연구 (Performance Characteristics of CA 19-9 Radioimmunoassay and Clinical Significance of Serum CA 19-9 Assay in Patients with Malignancy)

  • 김상은;송영기;조보연;김노경;고창순;이문호;홍성운;홍기석
    • 대한핵의학회지
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    • 제19권1호
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    • pp.119-126
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    • 1985
  • To evaluate the performance characteristics of CA 19-9 radioimmunoassay and the clinical significance of serum CA 19-9 assay in patients with malignancy, serum CA 19-9 levels were measured by radioimmunoassay using monoclonal antibody in 135 normal controls, 81 patients with various untreated malignancy, 9 patients of postoperative colon cancer without recurrence and 20 patients with benign gastrointestinal diseases, who visited Seoul National University Hospital from June, 1984 to March, 1985. The results were as follows; 1) The CA 19-9 radioimmunoassay was simple to perform and can be completed in one work day. And the between-assay reproducibility and the assay recovery were both excellent. 2) The mean serum CA 19-9 level in 135 normal controls was $8.4{\pm}4.2U/mL$. Normal upper limit of serum CA 19-9 was defined as 21.0 U/mL. 4 out of 135(3.0%) normal controls showed elevated CA 19-9 levels above the normal upper limit. 3) One out of 20(5.0%) patients with benign gastrointestinal diseases showed elevated serum CA 19-9 level above the normal upper limit. 4) In 81 patients with various' untreated malignancy, 41 patients(50.6%) showed elevated serum CA 19-9 levels. 66.7% of 18 patients with colorectal cancer, 100% of 2 patients with pancreatic cancer, 100% of 3 patients with common bile duct cancer, 47.1% of 17 patients with stomach cancer, 28.6% of 28 patients with hepatoma and 60.0% of 5 other gastrointestinal tract cancers showed elevated serum CA 19-9 levels. 5) The sensitivities of serum CA 19-9 related to resectability in colorectal and stomach cancer were 33.3% in resectable colorectal cancer, 83.3% in unresectable colorectal cancer, 41.7% in resectable stomach cancer, 60.0% in unresectable stomach cancer respectively. 6) The sensitivity of serum CA 19-9 in 9 patients of postoperative colorectal cancer without recurrence were 33.3% and significantly decreased compared with that of untreated colorectal cancer, 66.7% (p<0.05). 7) In patients with colorectal cancer, simultaneous measurement of serum CA 19-9 and serum CEA levels increased sensitivities. From above results, we concluded that serum CA 19-9 radioimmunoassay is simple to perform and reproducible, and is a useful indicator reflecting tumor extent and responses to the treatment in patients with malignancy.

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