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Correlation of Oocyte Quality with Fertilization and Embryonic Development in Intracytoplasmic Sperm Injection Treatment (세포질내 정자주입술 시행시 난자의 상태에 따른 수정률과 배아의 발생양상)

  • 임천규;전진현;송상진;김정욱;강인수
    • Development and Reproduction
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    • v.2 no.2
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    • pp.213-221
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    • 1998
  • Intracytoplasmic sperm injection (ICSI) has been widely used to treat couples with infertility due to severely impaired sperm charateristics and for whom conventional in-vitro fertilization (IVF) had failed. The extent to which the morphology of the oocyte at the light microscopy level is related to the results of ICSI vis controversial. In this study, oocytes from 44 patients were reviewed. The ICSI procedure was recorded through CCD camera. The oocytes were divided into five groups according to the presence of cytoplasmic inclusions, the width of perivitelline space (PVS), the presence of cell debris in PVS, the status of first polar body and the flexibility of oolemma. The results showed that the fertilization rate and embryonic development were not associated with the morphological criteria of oocyte. The degeneraton rate of oocytes after ICSI was significantly higher (P<0.001) in the oocytes whose membranes were broken at the moment of insertion (17.7%) than the oocytes whose membranes were broken by aspiration of cytoplasm (1.6%). More oocytes with cytoplasmic inclusions (48.4% vs. 25.1%, p<0.001), wide PVS (35.2% vs. 19.0%, p<0.001), or cell debris in PVS (53.3% vs. 38.4%, p<0.05) were observed in patients with female factor infertility compared to patients with male factor infertility. These results .suggest that the fertilization rate and embryonic development after ICSI are not correlated with oocyte morphology based on the presence of cytoplasmic inclusions, size of PVS, the presence of cell debris in PVS and the status of polar body. And the degeneration rate of oocytes after ICSI was associated with the flexibility of oolemma.

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A Biomechanical Study on the Various Factors of Vertebroplasty Using Image Analysis and Finite Element Analysis (의료영상 분석과 유한요소법을 통한 추체 성형술의 다양한 인자들에 대한 생체 역학적 효과 분석)

  • 전봉재;권순영;이창섭;탁계래;이권용;이성재
    • Journal of Biomedical Engineering Research
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    • v.25 no.3
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    • pp.171-182
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    • 2004
  • This study investigates the biomechanical efficacies of vertebroplasty which is used to treat vertebral body fracture with bone cement augmentation for osteoporotic patients using image and finite element analysis. Simulated models were divided into two groups: (a) a vertebral body, (b) a functional spinal unit(FSU). For a vertebral body model, the maximum axial displacement was investigated under axial compression to evaluate the effect of structural integrity. The stiffness of each FE model simulated was normalized by the stiffness of intact model. In the case of FSU model, 3 types of compression fractures were formulated to assess the influence on spinal curvature changes. The FSU models were loaded under compressive pressure to calculate the change of spinal curvature. The results according to the various factors suggest that vertebroplasty has the biomechanical efficacy of the increment of structural reinforcement in a patient who has relatively high level of BMD and a patient with the amount of 15%, PMMA injection of the cancellous bone volume. The spinal curvatures after compression fracture simulation vary from 9$^{\circ}$ to 17$^{\circ}$ of kyphosis compared to that the spinal curvature of normal model was -2.8$^{\circ}$ of lordosis. These spinal curvature changes cause the severe spinal deformity under the same loading. As the degree of compressive fracture increases the spinal deformity also increases. The results indicate that vertebroplasty has the increasing effect of the structural integrity regardless of the amount of PMMA or BMD and the restoration of decreased vertebral body height may be an important factor when the compressive fracture caused the significant height loss of vertebral body.

The Impact of Electricity Price Change on the Income Distribution (전력요금인하(電力料金引下)가 소득분배(所得分配)에 미치는 영향(影響))

  • Song, Dae-hee
    • KDI Journal of Economic Policy
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    • v.13 no.1
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    • pp.135-149
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    • 1991
  • The economic policy of decreasing the electricity price is widely understood to have the effect of stabilizing the general price level and improving the income distribution. However, the impact of electricity price decrease on the income distribution is not quite sure although the electricity price decrease would increase the disposable income of all households. The electricity price change would affect the income distribution through three channels. The first impact on the income distribution is made through the electricity price sructure; Korean electricity price structure is designed to subsidized the industrial sector at the cost of household consumption sector in the sense that the price per unit electricity for industrial sector is much lower than that for household consumption sector. The second impact on the income distribution is created through the disposable household income effect of the price decrease; Relative disposable income effect among households appeared higher to lower income household group and this relative disposable income effect seem to improve the income distribution although the net effect is very small. The third impact on the income distribution is formulated through the net profit effect of entreprise sector; This unearned net profit increase to the already rich industrial entrepreneurs group could create a negative income distribution effect. A simulation of 10% electricity price decrease with all the price structure given was attempted to calculate the net effect of income distribution and it was found the net income distribution effect of flat electricity price decrease to be negative contrary to the general understanding. The income distribution effect would only be one criterion among many other criteria considered in the electricity price making process. The electricity price decrease would be helpful to the price stabilization and price competitiveness of industrial sector. However, it does not improve the general income distribution status by the electricity price decrease with the price structure given.

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A Polarization-based Frequency Scanning Interferometer and the Measurement Processing Acceleration based on Parallel Programing (편광 기반 주파수 스캐닝 간섭 시스템 및 병렬 프로그래밍 기반 측정 고속화)

  • Lee, Seung Hyun;Kim, Min Young
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.8
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    • pp.253-263
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    • 2013
  • Frequency Scanning Interferometry(FSI) system, one of the most promising optical surface measurement techniques, generally results in superior optical performance comparing with other 3-dimensional measuring methods as its hardware structure is fixed in operation and only the light frequency is scanned in a specific spectral band without vertical scanning of the target surface or the objective lens. FSI system collects a set of images of interference fringe by changing the frequency of light source. After that, it transforms intensity data of acquired image into frequency information, and calculates the height profile of target objects with the help of frequency analysis based on Fast Fourier Transform(FFT). However, it still suffers from optical noise on target surfaces and relatively long processing time due to the number of images acquired in frequency scanning phase. 1) a Polarization-based Frequency Scanning Interferometry(PFSI) is proposed for optical noise robustness. It consists of tunable laser for light source, ${\lambda}/4$ plate in front of reference mirror, ${\lambda}/4$ plate in front of target object, polarizing beam splitter, polarizer in front of image sensor, polarizer in front of the fiber coupled light source, ${\lambda}/2$ plate between PBS and polarizer of the light source. Using the proposed system, we can solve the problem of fringe image with low contrast by using polarization technique. Also, we can control light distribution of object beam and reference beam. 2) the signal processing acceleration method is proposed for PFSI, based on parallel processing architecture, which consists of parallel processing hardware and software such as Graphic Processing Unit(GPU) and Compute Unified Device Architecture(CUDA). As a result, the processing time reaches into tact time level of real-time processing. Finally, the proposed system is evaluated in terms of accuracy and processing speed through a series of experiment and the obtained results show the effectiveness of the proposed system and method.

The Effect of Home economic education teaching plans for students in academic and those in vocational high schools' 'Preparation for Successful aging' in the 'Family life in old age' unit -A comparative study between practical problem-teaching lesson plans and instructor-led teaching and learning plans- (인문계와 가사.실업 전문계 고등학생의 '성공적인 노후생활 준비교육'을 위한 가정과 수업의 적용과 효과 -실천적 문제 중심 수업과 강의식 수업을 중심으로-)

  • Lee, Jong-Hui;Cho, Byung-Eun
    • Journal of Korean Home Economics Education Association
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    • v.23 no.4
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    • pp.105-124
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    • 2011
  • To achieve this objective, practical problem-teaching lesson plans and instructor-led teaching and learning plans were developed and integrated into the Technology Home Economics, and Human Development curricula at both academic and vocational high schools. The impact of these plans was examined, as were connections between the teaching methods and types of schools. As part of this study, a survey was conducted on 1,263 students in 46 classes at 6 randomly selected high schools: 4 academic and 2 vocational. A total of 9 teachers conducted classes for both experimental and comparative groups between October 2009 and November 2010. Pre- and post-tests were used to study the impact of the lessons on the experimental and comparative groups. In terms of data analysis and statistics processing, this study implemented mean and standard deviations, t-test, and analysis of covariance using the SPSS 12.0 program. The results of this study are as follows. The practical problem-teaching lessons produced more positive results in the students than the instructor-led lessons, in terms of their image of the elderly, their level of knowledge about them, their understanding of their need for welfare services, and preparation for Successful aging. When comparing the results by type of school, the experimental groups at academic high schools appeared to have a more positive image and better understanding of the elderly and their need for welfare services, and were better prepared for Successful aging than during their previous lessons. They also showed an increase in independence from their children in aging. As for the comparative groups, students at academic high schools showed an increase in preparation for Successful aging compared to the previous lessons. Finally, as for future research on preparation for aging in high schools, more schools should include this subject in their regular curriculum for Technology Home Economics, Human Development and Home Economics in order to generalize the results, and they need to evaluate the content. Additionally, this study suggests that new high school curricula should include lessons on preparation for aging so that students can deal successfully with our aging society.

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High Speed Rail Station Distric Using Entropy Model Study to Estimate the Trip Distribution (엔트로피 모형을 활용한 고속철도 역세권 통행분포 추정에 관한 연구)

  • Cho, Hangung;Kim, Sigon;Kim, Jinhowan;Jeon, Sangmin
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.32 no.6D
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    • pp.679-686
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    • 2012
  • KTX step 1 April 2004, after the opening, the second phase of the project was opened in November 2010. High-speed rail after the opening and continue to increase the demand of high-speed rail, Have the speed of competitive advantage compared too the means of transportation. The opening of these high-speed rail has led to changes of the move, the company's position, and the spatial structure of the population of reorganization, such as the social, economic, transportation. In this study, survey data using the High Speed Rail Station EMME/2 of the program to take advantage of the 2-Dimentional Blancing trip distribution to investigate the passage through the trip distribution by the estimation of the parameters of the model to estimate the distribution of the means of access and high-speed rail station to reproduce and Analysis of the results by means of access parameters (${\theta}$) autos 0.0395, buses 0.0390, subway 0.0650, taxi 0.0415, the frequency distribution (Trip Length Frequency Distribution: TLFD) were analyzed survey data value model with the results of comparing $R^2$ cars analysis and model values similar survey data 0.909 bus 0.923, subway 0.745 to 0.922, taxi, F test P value analysis is smaller than 0.05 at the 95% confidence level as a note that was judged to have been. Trip frequency distribution analysis, but in the future, set the unit to 5km-trip frequency distribution middle zone Units from small zone units (administrative district) segmentation research is needed, and can reflect the trip distance 0~5 km interval combined function to take advantage of the gravity model and the 3-Dimentional Blancing applied research is needed to be considered.

Geoacoustic characteristics of Quaternary stratigraphic sequences in the mid-eastern Yellow Sea (황해 중동부 제4기 퇴적층의 지음향 특성)

  • Jin, Jae-Hwa;Jang, Seong-Hyeong;Kim, Seong-Pil;Kim, Hyeon-Tae;Lee, Chi-Won;Chang, Jeong-Hae;Choi, Jin-Hyeok;Ryang, Woo-Heon
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.6 no.2
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    • pp.81-92
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    • 2001
  • According to analyses of high-resolution seismic profiles (air gun, sparker, and SBP) and a deep-drill core(YSDP 105) in the mid-eastern Yellow Sea, stratigraphic and geoacoustic models have been established and seismo-acoustic modeling has been fulfilled using ray tracing of finite element method. Stratigraphic model reflects seismo-, litho-, and chrono-stratigraphic sequences formed under a significant influence of Quaternary glacio-eustatic sea-level fluctuations. Each sequence consists of terrestrial to very-shallow-marine coarse-grained lowstand systems tract and tidal fine-grained transgressive to highstand systems tract. Based on mean grain-size data (121 samples) of the drill core, bulk density and P-wave velocity of depositional units have been inferred and extrapolated down to a depth of the recovery using the Hamilton's regression equations. As goo-acoustic parameters, the 121 pairs of bulk density and P-wave velocity have been averaged on each unit of the stratigraphic model. As a result of computer ray-tracing simulation of the subsurface strata, we have found that there are complex ray paths and many acoustic-shadow zones owing to the presence of irregular layer boundaries and low-velocity layers.

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The Comparison of Clinical Study of Off Pump and On Pump CABG (On Pump-CABG와 Off Pump-CABG의 임상적 고찰에 관한 비교연구)

  • 유경종;임상현;송석원;김치영;홍유선;장병철
    • Journal of Chest Surgery
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    • v.35 no.4
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    • pp.261-266
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    • 2002
  • In an attempt to avoid the adverse effects of the cardiopulmonary bypass, off pump coronary artery bypass grafting(Off pump CABG) that has recently been rediscovered and refined. We compared the preoperative risk factors and in-hospital outcomes of patients done Off pump with those done On pump CABG. Material na Method: One hundred seventy eight patients was underwent CABG between January 2001 and July 2001 12 patients whom underwent associated valvular or left ventricular volume reduction surgery were excluded in this study Data were collected for 52 Off pump CABG and 114 On pump CABG for patient and disease risk factors, extent of coronary disease, and in-hospital outcomes. Result: Off pump CABG and On pump CABG groups did not show any differences in their patient and disease risk factors, and extent of coronary disease. Off pump CABG group had significantly lower mean operation time(234 $\pm$ 37 min vs 290 $\pm$ 48 min, p<0.001), lower mean CK-MB level(10.1 $\pm$ 13.5 IU/L vs 33.1 $\pm$ 18.2 IU/L, p<0.001) and mean ventilation time(14.8 $\pm$ 3.5 hours vs 16.2 $\pm$ 4.9 hours, p=0.048) than On pump CABG groups. On pump CABG group had significantly more distal grafts(3.4 $\pm$ 0.9 vs 2.6 $\pm$ 0.8, p<0.001) than Off pump CABG groups. There were no operative mortality in two groups. Off pump) CABG and On pump CABG groups did not show any differences in their postoperative complications and outcomes including perioperative myocardial infarction, stroke, respiratory failure, renal failure, reoperation, the amount of bleeding, the need of intraaortic balloon pump, the need of inotropics, and the stay of intensive care unit and hospital. Two patients were converted to On pump CABG. Conclusion: This study showed that patients having Off pump CABG are not exposed to a greater risks of adverse outcomes and also provided evidence that patients having Off pump CABG have significantly lower operation time, CK-MB, ventilation time and less distal grafts. Although there may be potential benefits to Off pump CABG, further studies must be directed to determine those patients who would benefit from Off pump CABG.

Effects of Dietary Silicate Based Complex Mineral on Performance, Egg Quality and Immunological Competence in Laying Hens (규산염 복합광물질의 급여가 산란계의 생산능력, 계란품질 및 면역능력에 미치는 영향)

  • Lim, Chun Ik;Park, Jin Ern;Kim, Sang Eun;Choe, Ho Sung;Ryu, Kyeong Seon
    • Korean Journal of Poultry Science
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    • v.44 no.4
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    • pp.267-274
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    • 2017
  • This study was conducted to investigate the effect of feeding with dietary silicate based complex mineral (SCM) on the performance of laying hens. SCM at five levels (0%, 0.2%, 0.4%, 0.6% and 0.8%) was added to commercial diets, and fed to four hundred fifty Hy-Line Brown from fifty four to sixty five weeks of age. Egg production increased as the addition of dietary SCM to basal diets increased up to 0.6% (P<0.05). Furthermore, Feed intake increased in a manner similar to that of egg production (P<0.05). However, there was no difference in feed efficiency among the treatments. Eggshell thickness and breaking strength were significantly higher for the chickens fed with SCM than control from sixty weeks old to the end of experiment (P<0.05). Similarly, albumen height and Haugh unit were significantly higher for the chickens fed with SCM compared to those of control group (P<0.05). AST of birds fed SCM showed significantly higher than control (P<0.05). However, blood neutral fat level tended to increase in SCM treatments. Moreover, bone mineral density increased with SCM addition up to 0.4% (P<0.05). IL-2 (Interleukin-2) and IL-6 (Interleukin-6) levels appeared to be improved in the chickens fed with SCM addition diets, although not statistically different from all treatments. The results of this study indicated that the optimum SCM for improving the performance, egg quality and immunological competence of laying hens from 54 to 65 weeks of age was 0.6%.

Effect of dietary fermented spent mushroom (Hypsizygus marmoreus) substrates on laying hens (느티만가닥버섯 수확후배지 발효사료 급여가 산란계에 미치는 영향)

  • Kim, Su Cheol;Moon, Yea Hwang;Kim, Hay Soo;Kim, Hong Chul;Kim, Jong Ok;Cheong, Jong-Chun;Cho, Soo Jeong
    • Journal of Mushroom
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    • v.12 no.4
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    • pp.350-356
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    • 2014
  • This study was conducted to evaluate the feeding value of the spent mushroom (Hypsizygus marmoreus) substrates (SMS) in laying hens (Hy-Line Brown). The fresh spent mushroom (Hypsizygus marmoreus) substrates collected from the Namkyung farm were fermented with Bacillus subtilis EJ3 for 2 weeks. A total of twenty-four laying hens were fed corn-soy based experimental diets containing 0% (T0), 5% (T1), 10% (T2) and 15%(T3) fermented SMS for 12 weeks. There were no significant differences among the treatments in egg production, egg weight, egg mass, feed conversion and viability during the experimental period. Feed intake was significantly lowered in T0 (118.3 g) than T1 (121.9 g), T2 (120.3 g) and T3 (122.4 g). There were no significant differences among the treatments eggshell breaking strength, thickness and haugh unit, whereas the yolk color of T1, T2 and T3 were significantly heavy than T0. The palatability of boiled meat was significantly better in the T3 laying hens than in the T0 laying hens. In conclusion, fermented SMS can be used as resource of feed in laying hen feed at 5.0-15% level without effect on performance and egg qualify.