• Title/Summary/Keyword: Uniaxial stretching

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Development of wrinkled skin-on-a-chip (WSOC) by cyclic uniaxial stretching

  • Lim, Ho Yeong;Kim, Jaewon;Song, Hyun Jeong;Kim, Kyunghee;Choi, Kyung Chan;Park, Sungsu;Sung, Gun Yong
    • Journal of Industrial and Engineering Chemistry
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    • v.68
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    • pp.238-245
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    • 2018
  • The skin experiences constant physical stimuli, such as stretching. Exposure to excessive physical stimuli stresses the skin and can accelerate aging. In this study, we applied a method that allowed human fibroblasts and keratinocytes to be perfused with media to form 3D skin equivalents that were then uniaxially 10%-stretched for 12 h per day (at either 0.01 or 0.05 Hz) for up to 7 days to form wrinkled skin-on-a-chip (WSOC). There was more wrinkling seen in skin equivalents under 0.01 Hz uniaxial stretching than there was for non-stretched skin equivalents. At 0.05 Hz, the stratum corneum almost disappeared from the skin equivalents, indicating that stretching was harmful for the epidermis. At both frequencies, the production of collagen and related proteins in the skin equivalents, such as fibronectin 10 and keratin, decreased more than those in the non-stretched equivalents, indicating that the dermis also suffered from the repeated tensile stress. These results suggest that WSOCs can be used to examine skin aging and as an in vitro tool to evaluate the efficacy of anti-wrinkle cosmetics and medicines.

A study on the development of high strength for acryl fiber during uniaxial stretching by swell-wet process (팽윤습열연신에 의한 아크릴섬유의 고강도화에 관한 연구)

  • Song, Kyoung-Hun;Lee, Mun-Soo
    • The Journal of Natural Sciences
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    • v.8 no.1
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    • pp.145-151
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    • 1995
  • The stretching of synthetic fibers by hot dry process is very difficult, because these fibers have high glass transition temperature at above $150^{\circ}C$. But, we used a swell-wet stretching precess; the fibers are stretched in a swelling agent such as organic solvents at lower temperature. In this study, 100% acryl fibers were uniaxially stretched with free width at $70^{\circ}C$ by swell-wet process in organic solvents. The stretchability was estimated by stretching work. This work is concerned with stretching stress and strain, and initial modulus. We found that it is a good parameter for the estimatation of high strength to the acrylic fiber. The effects of stretching conditions on the molecular orientation for high strength and mechanical properties of PAN fibers were measured.

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Effect of Initial Textures on the Plane Strain Stretching (판재의 초기집합조직이 평면변형률 스트레칭 변형에 미치는 영향)

  • Bae, Seok-Yong;Lee, Yong-Sin
    • Transactions of Materials Processing
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    • v.7 no.5
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    • pp.459-464
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    • 1998
  • Effect of the several initial textures such as random texture, rolling texture and cube texture, on the plane strain stretching was studied by interpretation of the finite element method. The calculation of yield locus indicated that the sheet oriented in the cube texture exhibits easy yielding on uniaxial stress state whereas the sheet having either a random or the rolling texture exhibits easy yielding on shear deformation. Upon stretching tests, the thickness strain at the center region contacting the punch was identical regardless of the initial textures while the dependence of the thickness strain on the initial texture was found in the other regions. In general punch loads required or the sheet with an initial cube texture was as expected from calculated yield locus, lower than those for the others.

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Analysis of Stretching of Perforated Sheets for Shadow masks (섀도마스크용 천공판의 신장성형 해석)

  • 백승철;한흥남;오규환;이동녕
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 1994.10a
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    • pp.25-32
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    • 1994
  • In order to analyse stretching of perforated sheets for shadow masks by the finite element method for use with the associated flow rule, yield functions which can explain the yield stresses and the apparent plastic contraction ratios of the sheets have been obtained. Coefficients in the yield functions could be determined from the measured apparent plastic contraction ratios under uniaxial tension. Using this yield function and estimated coefficients, the stretching of hole-type and slot-type sheets has been analysed and compared with the experimental results. The calculated results were in good agreement with the experimental results.

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Analytical Study for the Prediction of Mechanical Properties of a Fiber Metal Laminate Considering Residual Stress (잔류응력을 고려한 섬유 금속 적층판의 기계적 물성치 예측에 관한 이론적 연구)

  • Kang, D.S.;Lee, B.E.;Park, E.T.;Kim, J.;Kang, B.S.;Song, W.J.
    • Transactions of Materials Processing
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    • v.23 no.5
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    • pp.289-296
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    • 2014
  • Uniaxial tensile tests were conducted to accurately evaluate the in-plane mechanical properties of fiber metal laminates (FMLs). The FMLs in the current study are comprised of a layer of self-reinforced polypropylene (SRPP) sandwiched between two layers of aluminum alloy 5052-H34. The nonlinear tensile behavior of the FMLs under in-plane loading conditions was investigated using both numerical simulations and a theoretical analysis. The numerical simulation was based on finite element modeling using the ABAQUS/Explicit code and the theoretical constitutive model was based on the volume fraction approach using the rule of mixture and a modification of the classical lamination theory, which incorporates the elastic-plastic behavior of the aluminum alloy and the SRPP. The simulations and the model are used to predict the inplane mechanical properties such as stress-strain response and deformation behavior of the FMLs. In addition, a post-stretching process is used to reduce the thermal residual stresses before uniaxial tensile testing of the FMLs. Through comparison of both the numerical simulations and the theoretical analysis with the experimental results, it is concluded that the numerical simulation model and the theoretical approach can describe with sufficient accuracy the actual tensile stress-strain behavior of the FMLs.

Numerical Analysis of Cyclic Deformation of Polymer Foam Film Using Stretched Truncated Octahedron Model (모서리가 제거된 팔면체 인장모델을 이용한 다공성 폴리머 박막의 반복변형거동 수치해석)

  • Yoo, Ui-Kyung;Lee, Young-Seog
    • Journal of the Korean Society for Precision Engineering
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    • v.27 no.3
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    • pp.104-110
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    • 2010
  • Cyclic deformations of polymer foam film are simulated using the finite element method. Material of polymer foam film is polypropylene (PP). The calculated polymer foam film is micro-scale thin film has cellular structure. The polymer foam film is used in ferro-electret applications. The polymer foam film is idealized to one cell structure as lens shaped stretched truncated octahedron model. Cyclic deformation is performed by uniaxial stretching. Stretching direction is perpendicular to plane of cellular film. Various cyclic strain amplitudes, pore wall thicknesses, pore shape are investigated to find deformation tendency of cellular structure. Consequently, cellular structure has various macroscopic stresses on cyclic deformation with various pore thickness and pore shape.

Development of a Tensile Cell Stimulator to Study the Effects of Uniaxial Tensile Stress on Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells (세포 인장 자극기의 개발과 세포 인장 자극을 통한 성체 줄기세포의 골분화 유도)

  • Shin, Hyun-Jun;Lee, Woo-Teak;Park, Suk-Hoon;Lee, Sun-Hwa;Park, Jung-Ho;Yoon, Yong-San;Shin, Jennifer H.
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.33 no.7
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    • pp.629-636
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    • 2009
  • Mechanical stimulation is known to play a vital role on the differentiation of mesenchymal stem cells (MSCs) to pre-osteoblasts. In this research, we developed a tensile cell stimulator, composed of a DC motor-driven actuator and LVDT sensor for measuring linear displacement, to study the effects of tensile stress on osteogenic differentiation of MSCs. First, we demonstrated the reliability of this device by showing the uniform strain field in the silicon substrate. Secondly, we investigated the effects of tensile stretching on osteogenic differentiation. We imposed a pre-set cyclic strain at a fixed frequency on cell monolayer cultured on a flexible silicon substrate while varying its amplitude and duration. 60 min of resting period was allowed between 30 min of cyclic stretching and this cycle is repeated up to 7 days. Under the combined stimulation with osteogenic media and mechanical stretching, the osteogenic markers such as alkaline phosphatase (ALP), osterix, and osteopontin began to get expressed as early as 4 days of stimulation, which is much shorter than what is typically required for osteogenic media induced differentiation. Moreover, different markers were induced at different magnitudes of the applied strains. Lastly, for the case of ALP, we observed the antagonistic effects of osteogenic media when combined with mechanical stretching.

Buckling analysis of FG plates via 2D and quasi-3D refined shear deformation theories

  • Lemya Hanifi Hachemi Amar;Fouad Bourada;Abdelmoumen Anis Bousahla;Abdelouahed Tounsi;Kouider Halim Benrahou;Hind Albalawi;Abdeldjebbar Tounsi
    • Structural Engineering and Mechanics
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    • v.85 no.6
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    • pp.765-780
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    • 2023
  • In this work, a novel combined logarithmic, secant and tangential 2D and quasi-3D refined higher order shear deformation theory is proposed to examine the buckling analysis of simply supported uniform functionally graded plates under uniaxial and biaxial loading. The proposed formulations contain a reduced number of variables compared to others similar solutions. The combined function employed in this study ensures automatically the zero-transverse shear stresses at the free surfaces of the structure. Various models of the material distributions are considered (linear, quadratic, cubic inverse quadratic and power-law). The differentials stability equations are derived via virtual work principle with including the stretching effect. The Navier's approach is applied to solve the governing equations which satisfying the boundary conditions. Several comparative and parametric studies are performed to illustrates the validity and efficacity of the proposed model and the various factors influencing the critical buckling load of thick FG plate.

A Study on the Drawing and Rupture of Uniaxial Stretched Polyvinylalcohol Film in Water (수중 일축신장 플리비닐알콜 필름의 연신과 파단에 관한 연구)

  • Kim, Wan-Soo;Lee, Kwang-Bae;Matsumoto, Kiyoichi
    • Journal of the Korean Society of Clothing and Textiles
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    • v.13 no.4
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    • pp.427-436
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    • 1989
  • Poly (vinyl alcohol) films, which .were annealed at various different annealing conditions, were carried out by uniaxial stretching them with free width in water and were investigated drawing behaviours and rupture phenomena. l) After dipping the specimen into the water, it took about 15 min. for the specimen's swelling to approach to equilibrium. 2) When the film annealed at $180^{\circ}C$ for 10 min. was drawn at $20^{\circ}C$. it was shown very toughness. 3) By means of birefringence measurements, the total molecular orientation of the annealed films increased until the draw ratio of 4, but drawing them above the draw ratio of 5, that of untreated films increased. 4) In the case of the mechanical properties of the drawn films. the annealed films tended to good trend for the draw ratios between 1 and 4. but drawing them above the draw ratio of 5. the untreated films tended to good trend for them.

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