• Journal of Industrial and Engineering Chemistry
• /
• 제68권
• /
• pp.238-245
• /
• 2018

The skin experiences constant physical stimuli, such as stretching. Exposure to excessive physical stimuli stresses the skin and can accelerate aging. In this study, we applied a method that allowed human fibroblasts and keratinocytes to be perfused with media to form 3D skin equivalents that were then uniaxially 10%-stretched for 12 h per day (at either 0.01 or 0.05 Hz) for up to 7 days to form wrinkled skin-on-a-chip (WSOC). There was more wrinkling seen in skin equivalents under 0.01 Hz uniaxial stretching than there was for non-stretched skin equivalents. At 0.05 Hz, the stratum corneum almost disappeared from the skin equivalents, indicating that stretching was harmful for the epidermis. At both frequencies, the production of collagen and related proteins in the skin equivalents, such as fibronectin 10 and keratin, decreased more than those in the non-stretched equivalents, indicating that the dermis also suffered from the repeated tensile stress. These results suggest that WSOCs can be used to examine skin aging and as an in vitro tool to evaluate the efficacy of anti-wrinkle cosmetics and medicines.

• 자연과학논문집
• /
• 제8권1호
• /
• pp.145-151
• /
• 1995

건열일축연신법에 의한 합성섬유의 연신은 높은 유리전이온도 때문에 대략 $150^{\circ}C$이상의 온도에서 행하여 지고 있다. 그러나, 팽윤습열연신법은 유기용매를 팽윤제로 사용하여 미세구조를 변화시키기 때문에 낮은 온도에서 연신 할 수 있는 특징을 갖고 있다. 본 연구에서는 비교적 낮은 온도인 $70^{\circ}C$에서 팽윤습열 일축연신에 의한 100% 아크릴섬유의 고강도화에 대하여 연구하였다. 연신능력은 연신일에 의하여 계상하였으며, 이 연신일은 연신응력과 변형 그리고 초기영율에 의하여 좌우됨을 알 수 있었다. 연신은 아크릴 섬유의 고강도를 위해 필요한 요인임을 확인할 수 있었다. 또한, 아크릴 섬유의 고강도화를 위한 분자배향도 및 결정화도 증가에 따른 연신조건의 효과와 물성 변화에 대하여 비교. 검토하였다.

• 한국섬유공학회:학술대회논문집
• /
• 한국섬유공학회 1987년도 제2차학술발표초록집
• /
• pp.12-13
• /
• 1987

• 소성∙가공
• /
• 제7권5호
• /
• pp.459-464
• /
• 1998

Effect of the several initial textures such as random texture, rolling texture and cube texture, on the plane strain stretching was studied by interpretation of the finite element method. The calculation of yield locus indicated that the sheet oriented in the cube texture exhibits easy yielding on uniaxial stress state whereas the sheet having either a random or the rolling texture exhibits easy yielding on shear deformation. Upon stretching tests, the thickness strain at the center region contacting the punch was identical regardless of the initial textures while the dependence of the thickness strain on the initial texture was found in the other regions. In general punch loads required or the sheet with an initial cube texture was as expected from calculated yield locus, lower than those for the others.

• 한국소성가공학회:학술대회논문집
• /
• 한국소성가공학회 1994년도 추계학술대회 논문집
• /
• pp.25-32
• /
• 1994

In order to analyse stretching of perforated sheets for shadow masks by the finite element method for use with the associated flow rule, yield functions which can explain the yield stresses and the apparent plastic contraction ratios of the sheets have been obtained. Coefficients in the yield functions could be determined from the measured apparent plastic contraction ratios under uniaxial tension. Using this yield function and estimated coefficients, the stretching of hole-type and slot-type sheets has been analysed and compared with the experimental results. The calculated results were in good agreement with the experimental results.

• 소성∙가공
• /
• 제23권5호
• /
• pp.289-296
• /
• 2014

Uniaxial tensile tests were conducted to accurately evaluate the in-plane mechanical properties of fiber metal laminates (FMLs). The FMLs in the current study are comprised of a layer of self-reinforced polypropylene (SRPP) sandwiched between two layers of aluminum alloy 5052-H34. The nonlinear tensile behavior of the FMLs under in-plane loading conditions was investigated using both numerical simulations and a theoretical analysis. The numerical simulation was based on finite element modeling using the ABAQUS/Explicit code and the theoretical constitutive model was based on the volume fraction approach using the rule of mixture and a modification of the classical lamination theory, which incorporates the elastic-plastic behavior of the aluminum alloy and the SRPP. The simulations and the model are used to predict the inplane mechanical properties such as stress-strain response and deformation behavior of the FMLs. In addition, a post-stretching process is used to reduce the thermal residual stresses before uniaxial tensile testing of the FMLs. Through comparison of both the numerical simulations and the theoretical analysis with the experimental results, it is concluded that the numerical simulation model and the theoretical approach can describe with sufficient accuracy the actual tensile stress-strain behavior of the FMLs.

• 한국정밀공학회지
• /
• 제27권3호
• /
• pp.104-110
• /
• 2010

Cyclic deformations of polymer foam film are simulated using the finite element method. Material of polymer foam film is polypropylene (PP). The calculated polymer foam film is micro-scale thin film has cellular structure. The polymer foam film is used in ferro-electret applications. The polymer foam film is idealized to one cell structure as lens shaped stretched truncated octahedron model. Cyclic deformation is performed by uniaxial stretching. Stretching direction is perpendicular to plane of cellular film. Various cyclic strain amplitudes, pore wall thicknesses, pore shape are investigated to find deformation tendency of cellular structure. Consequently, cellular structure has various macroscopic stresses on cyclic deformation with various pore thickness and pore shape.

• 대한기계학회논문집A
• /
• 제33권7호
• /
• pp.629-636
• /
• 2009

Mechanical stimulation is known to play a vital role on the differentiation of mesenchymal stem cells (MSCs) to pre-osteoblasts. In this research, we developed a tensile cell stimulator, composed of a DC motor-driven actuator and LVDT sensor for measuring linear displacement, to study the effects of tensile stress on osteogenic differentiation of MSCs. First, we demonstrated the reliability of this device by showing the uniform strain field in the silicon substrate. Secondly, we investigated the effects of tensile stretching on osteogenic differentiation. We imposed a pre-set cyclic strain at a fixed frequency on cell monolayer cultured on a flexible silicon substrate while varying its amplitude and duration. 60 min of resting period was allowed between 30 min of cyclic stretching and this cycle is repeated up to 7 days. Under the combined stimulation with osteogenic media and mechanical stretching, the osteogenic markers such as alkaline phosphatase (ALP), osterix, and osteopontin began to get expressed as early as 4 days of stimulation, which is much shorter than what is typically required for osteogenic media induced differentiation. Moreover, different markers were induced at different magnitudes of the applied strains. Lastly, for the case of ALP, we observed the antagonistic effects of osteogenic media when combined with mechanical stretching.

• Structural Engineering and Mechanics
• /
• 제85권6호
• /
• pp.765-780
• /
• 2023

In this work, a novel combined logarithmic, secant and tangential 2D and quasi-3D refined higher order shear deformation theory is proposed to examine the buckling analysis of simply supported uniform functionally graded plates under uniaxial and biaxial loading. The proposed formulations contain a reduced number of variables compared to others similar solutions. The combined function employed in this study ensures automatically the zero-transverse shear stresses at the free surfaces of the structure. Various models of the material distributions are considered (linear, quadratic, cubic inverse quadratic and power-law). The differentials stability equations are derived via virtual work principle with including the stretching effect. The Navier's approach is applied to solve the governing equations which satisfying the boundary conditions. Several comparative and parametric studies are performed to illustrates the validity and efficacity of the proposed model and the various factors influencing the critical buckling load of thick FG plate.

• 한국의류학회지
• /
• 제13권4호
• /
• pp.427-436
• /
• 1989

Poly (vinyl alcohol) films, which .were annealed at various different annealing conditions, were carried out by uniaxial stretching them with free width in water and were investigated drawing behaviours and rupture phenomena. l) After dipping the specimen into the water, it took about 15 min. for the specimen's swelling to approach to equilibrium. 2) When the film annealed at $180^{\circ}C$ for 10 min. was drawn at $20^{\circ}C$. it was shown very toughness. 3) By means of birefringence measurements, the total molecular orientation of the annealed films increased until the draw ratio of 4, but drawing them above the draw ratio of 5, that of untreated films increased. 4) In the case of the mechanical properties of the drawn films. the annealed films tended to good trend for the draw ratios between 1 and 4. but drawing them above the draw ratio of 5. the untreated films tended to good trend for them.