• Journal of Yeungnam Medical Science
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• v.15 no.1
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• pp.114-124
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• 1998

We analyzed the mammographic (n=21) findings (location, margin, shape, cluster microcalcifications, size, multiplicity) and ultrasonographic (n=12) findings (shape, border, internal echo, boundary echo, posterior echo, lateral echo, width/depth ratio) to evaluate specific radiologic findings of histopathologically proved uncommon breast cancer. The mammographic findings (n=21) are as follow; 1) single; 16, multiple; 5 2) margin (smooth; 13, irregular; 4, spiculated; 4) 3) shape (round and ovoid; 9, lobulated; 8, irregular; 4) 4) cluster micro calcifications (abscent; 20, present; 1) 5) size (1-3cm; 18, 3-5cm; 2, 5cm> ; 1) 6) location (UOQ; 13, UIQ; 4, LIQ; 3, LOQ; 1). The ultrasonographic findings (n=12) are as follow; 1) shape (round to oval; 5, lobulated; 5, irregular; 2) 2) border (smooth even; 9, rough uneven; 3) 3) internal echo (fine homogeneous; 5, coarse heterogeneous; 7) 4) boundary echo (regular fine; 4, irregular thick; 8) 5) posterior echo (enhanced; 11, no change; 1) 6) lateral echo (marked; 7, nonexistent; 5) 7) width/depth ratio (1.5> ; 1, 1.0-1.5; 7, 1.0< ; 4). Uncommon breast cancer show benign nature on mammogram, but malignant nature on ultrasonogram (especially boundary echo, internal echo, width/depth ratio).

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1901-1906
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• 2012

Background: The discovery that microRNA (miRNA) regulates metastasis provide a principal molecular basis for tumor heterogeneity. A characteristic of solid tumors is their heterogenous distribution of blood vessels, with significant hypoxia occurring in regions (centers of tumor) of low blood flow. It is necessary to discover the mechanism of breast cancer metastasis in relation to the fact that there is a differential distribution of crucial microRNA in tumors from centers to edges. Methods: Breast tissues from 48 patients (32 patients with breast cancer) were classified into the high invasive and metastatic group (HIMG), low invasive and metastatic group (LIMG), and normal group. Samples were collected from both the centers and edges of all tumors. The first six specimens were detected by microRNA array, and the second ten specimens were detected by real-time qRT-PCR and Western blot analyses. Correlation analysis was performed between the miRNAs and target proteins. Results: The relative content of miR-20a and miR-20b was lower in the center of the tumor than at the edge in the LIMG, lower at the edge of the tumor than in the center in the HIMG, and lower in breast cancer tissues than in normal tissues. VEGF-A and HIF-1alpha mRNA levels were higher in the HIMG than in the LIMG, and levels were higher in both groups than in the normal group; there was no difference in mRNA levels between the edge and center of the tumor. VEGF-A and HIF-1alpha protein levels were higher in the HIMG than in the LIMG, and protein levels in both groups were higher than in the normal group; there was a significant difference in protein expression between the edge and center of the tumor. Correlation analysis showed that the key miRNAs (miR-20a and miR-20b) negatively correlated with the target proteins (VEGF-A and HIF-1alpha). Conclusions: Our data suggest that miR-20a and miR-20b are differentially distributed in breast cancer, while VEGF-A and HIF-1alpha mRNA had coincident distributions, and VEGF-A and HIF-1alpha proteins had uneven and opposing distributions to the miRNAs. It appears that one of the most important facets underlying metastatic heterogeneity is the differential distribution of miR-20a and miR-20b and their regulation of target proteins.

• Journal of the Korean Institute of Intelligent Systems
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• v.24 no.3
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• pp.259-264
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• 2014

This paper is research paper on the MPD(Magnet Position Device) for the outdoor MGV(Magnet /Magnet Gyro Guidance Vehicle). Usually, MGV is used in indoor environment because of a measurement height of the magnet position device. CMPD(Commercial magnet position device) has 30 mm measurement height, so this is suitable structure in indoor environment like to a flat surface. Outdoor environment is an uneven and irregular, So Outdoor MGV must has a suspension. But CMPD is unsuitable for outdoor environment because of a collision with a surface caused by suspension. Thus, measurement height of the outdoor MPD is positively necessary more than 100 mm. So, we suggest the outdoor MPD using analog magnet hall sensor, moving average filter and Characteristic(rate of the magnet hall sensor) function of the localization. Result of the experiments, the proposed Magnet Position Device for the outdoor MGV has localization accuracy 4.31 mm, measurement height 150 mm and width 150 mm and is efficient more than CMPD.

• Journal of Korean Society of Forest Science
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• v.97 no.6
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• pp.597-604
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• 2008

Recognizing the necessity of the development of ecologically sound silvicultural system for the mature Korean pine (Pinus koraiensis), this study was carried out to examine the invasion and growth of understory vegetation after partial cutting. In 1997, the age class VII Korean pine forest in the Experimental Forest of Kangwon National University was opened up about 50% by modified shelterwood cutting with site preparation to induce succeeding regenerations. After 10 years, plenty of hardwood have come to the stand, forming understory vegetation. The abundance and composition of understory vegetation was periodically investigated in the ten $10m{\times}10m$ permanent sample plots, estimating importance values, species diversity index and the distribution of diameter and height of the understory vegetation. Encouraged by canopy opening, the coverage of understory reached perfect closure, composed of 22 tree species and 20 shrub species in 2007. Morus bombycis occupied 29.6% of the total importance value and Cornus controversa was 17.0%, followed by Styrax obassia, Quercus aliena, Quercus mongolica, Acer mono, and Pinus koraiensis. In the year of 2000 the species diversity was highest as 2.547 with 26 tree species and deceasing thereafter, showing 2.220 with 22 tree species in 2007. As understory layer was thickly covered and got grow bigger, some shade intolerant species were disappeared, lowering species diversity. In 2007 the biggest tree was a Quercus aliena with 11.3 cm of DBH and the tallest tree was a Cornus controversa with 9.8m of height. The frequency distribution of number of trees by diameter and height classes formed the inverted-J-shaped curve, supposed to be typical uneven-aged stand.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.2
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• pp.331-337
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• 2001

The effect of Phellinus linteus methanol extract on the lipid metabolism in the liver of rat was investigated in this study. Rats were randomly divided into 6 groups including the control, $CCl_4$and high fat group plus sub-groups with Phellinus linteus methanol extract administration. Methanol extracts of Phellinus linteus were fed 50mg/kg B.W daily via drinking water. A 1.2mL of $CCl_4/kg$ body weight was administered by oral intubation twice a week for total six times. The administration of $CCl_4$ increased total cholesterol, TG, LDL and LDL-phospholipid. However, the level of liver cholesterol and triglycerides were significantly decreased while HDL-cholesterol was increased by the extract feeding. The activities of GOT, GPT, AP and LDH were greatly enhanced by the extract feeding. Electronmicrograph showed that $CCl_4$ treatment deteriorated the structure of cytoplasmic matrix with its uneven distribution. However, the extract treatment reconstituted the damaged cytoplasm and stimulated mitochondriagenesis. From these results, it was suggested that Phellinus linteus can help to recover the damaged liver function and further may help to prevent senescence diseases such as fatty liver, hypertension and hyperlipidemia.

• Journal of the Korean association of regional geographers
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• v.21 no.4
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• pp.631-638
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• 2015

The aim of this article is to analyze problems of the government-led region-based business-university-research institute collaborations(BURIC) in Korea and to present main issues for solving and improving the current 'cul-de-sac' of these collaborations. The main problem of such collaborations is the wider divergence of opinions by actors who implement projects of the BURIC funded by the central and local government. Due to this problem, each region, mainly the non-Seoul metropolitan region, in Korea has problems of the system and people for BURIC. Within this context, main issues of the government-led and region-based BURIC is focused upon BURIC for the start-up of self-employment and the expansion of companies' lifespan. Since 2000, experts and policy-makers have emphasized business- (or company-) centered BURIC rather than University-focused one. This point of view should be improved or corrected. That is to say, policies of BURIC are in need of focusing upon the start-up for self-employment and the expansion of companies' lifespan.

• Journal of the Korean Geographical Society
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• v.46 no.4
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• pp.480-500
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• 2011

This paper aims to describe the rapid growth of the one-person households in terms of the socio-economic demographic perspectives during the period of 1995-2005 and to analyze the spatial distribution patterns based on different characteristics of one-person households. The increase in the divorce ratio in the middle-aged, the growth of unmarried people the young generation, and the increase of life expectancy in the old generation are explanatory factors for the rise and diversification of one-person households in Korea. The rapid increase of one-person households is accompanied by a diversification in their age, gender, marital status, education level. Uneven distribution of one-person households depends on their age, level of education and dwelling type. Highly educated young adults residing in their own apartment are generally concentrated in major cities, whereas senior citizen with their own single house who lives alone are mostly in rural area. One-person households of the highly educated young adults are significantly polarized in the light of their the living standards. In particular, metropolitan area or big cities are mixed with those who have their own apartment and are financially capacity and with those who rent in a detached single house. As such, one-person households have considerably heterogeneous characteristics. Therefore, each local government will face different economic and social problems based on which group of one-person households are increasing and where they are concentrated in. To this extent, the local government should have differentiated welfare policy according to its own respect.

• Economic and Environmental Geology
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• v.41 no.1
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• pp.81-92
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• 2008

Fonualei Rift and Spreading Center(FRSC) and Mangatolu Triple function(MTJ) caldera are located in northeastern part of Lau basin which is the active back-arc basin. Deep-tow and surface-tow magnetic surveys are carried out in FRSC. In deep-tow magnetic survey, to compensate for influence of uneven distance between bathymetry and sensor height, magnetic anomaly is continued upward to a level plane by using the Guspi method. We calculate crustal magnetization using Parker and Huestis's inversion algorithm, and try to find the hydrothermal vent and understand the structure of ocean floor crust. The result of deep-tow magnetic survey at FRSC showed that Central Anomaly Magnetization High(CAMH) recorded the max value of 4.5 A/m which is associated with active ridge. The direction of SSW-NNE corresponds with the direction of the principal spreading ridge in Lau basin. The low crustal magnetizaton$(174^{\circ}35.1'W,\;16^{\circ}38.4'S)$ of -4.0 A/m is supposed to correlate with submarine hydrothermal vent. Surface-tow magnetic data were collected in MTJ caldera$(174^{\circ}00'W,\;15^{\circ}20'S)$. The prevailing SSW-NNE direction of collapsing walls and the presence of CAMH at the center of caldera strongly indicate the existence of active spreading ridge in ancient times.

• Applied Chemistry for Engineering
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• v.20 no.6
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• pp.638-645
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• 2009

High alumina refractory used in a coal gasifier was analyzed and the degradation mechanism by molten slag was investigated. The depth of refractory severely damaged by slag varied between 12~40 mm, including the adhered slag layer. The sample also showed the cracks formed in parallel to the slag/refractory interface. The degree of degradation varied with the micro-structures in the refractory. Fused alumina grains showed the uneven boundary and pore formation just along the edges, while the tablet alumina showed the slag penetrated between sintered alumina around which the formation of Al-Fe phase was observed. Calcium aluminate cements were not observed at the high temperature zone near the slag/refractory interface, probably due to dissolution into molten slag. Around large grains of alumina, rod shape alumina, which appeared to be recrystallized during cooling, were observed, and large pores were also formed around those grains. Therefore, in high alumina refractories, hot molten slag dissolves the bonding phase and rod-shape alumina phase is recrystallized upon cooling. During this process, cracks are developed due to structural change, and the degradation occurs by physical causes such as structural spalling.

• Korean Journal of Soil Science and Fertilizer
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• v.11 no.2
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• pp.61-66
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• 1979

This experiment was conducted to find out the simple and economical method to improve physical properties of the soil that was very poor for the establishment of orchard. Jeonnam clay loam soils distributed mainly on rolling and hill side slope, were treated with the explosion of two kinds of dynamite at the depth of 1 m. The change of physical properties was investigated vertically and horizontally after soil profile had settled to some extent. The results were summarized as : 1. The original soil was very high in bulk density and soil hardness. Total porosity and aeration porosities were lower than critical level providing root elongation. It was more apparent in the subsoil than in the surface soil. 2. It was recognized that soil mass destruction and cracking by dynamite explosion decreased soil bulk density and soil hardness and increased porosity, especially non-capillary pores. 3. Effective radius of the improved physical properties by explosion with two dynamites was 100cm at 60cm depth and 30cm at 80cm depth. But with the use of three dynamites it was 100cm at 80cm depth. 4. It was thought that soil mass destruction and cracking caused by explosion was uneven in the two dynamites, and three dynamites was more effective to improve physical properties evenly. 5. With the use of two dynamites, Ammonium explosive was superior to gelatin dynamite.