• 한국실내디자인학회논문집
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• 제23권5호
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• pp.183-191
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• 2014

Children stage is an important period the foundation of growth is accomplished. During the period, children are the most sensitive to environmental effects and experiences and interactions with surroundings can make lots of effects on their physical and cognitive development. Under the background of the above contents, a representative institution of the society, which is helpful to cultivate children's reading habit, will be children library. The purposes of this research are to analyze intensively reading room among the children library's spatial organization and compare/analyze cases of children library's reading room with the elements of interior environment. The methods of research are theory study and case study. Through the on-the-site visiting and shooting, interior environment design was investigated and then, it was arranged, analyzed and evaluated. Cases were analyzed by elements of interior environment design evaluation. As the result, comfort was the highest and variety was the lowest. Especially, Songpa children library showed various factors generally through the various designs. 7 evaluative elements of children library's reading room were mutually different, but there was a certain different in relation of them. Especially, variety and flexibility must be more strengthened. So, children can interests and joy in reading room various designs are requested by getting out of library's uniformed furniture and arrangement plan.

• 대한간호학회지
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• 제3권2호
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• pp.91-100
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• 1973

I. Objectives of the study This study attempted In examine, from a pedagogical point of view, how socially-handicapped children differ from normal ones in their family backgrounds, personality-traits. adaptability to school life, and their peer relationship. This study was made under the following hypothesis; 1. The family background of socially-handicapped children is less desirable than that of normal ones. 2. Personality traits of socially-handicapped children are less desirable than those of normal ones. 3. Socially handicapped children tend to be less adaptable to school life than normal ones. 4. Peer-relationship of socially-handicapped children is less desirable than of normal ones . II. Contents of study The thesis consists of the following five main parts; 1. Introduction 2. Related Studies 3. Procedure 4. Results 5. Summary and Conclusions III. Instruments The following instruments were used for this study; 1. Family background record prepared by the school. 2. Questionnaire prepared by the writer. 3. General personality test (written by Kim Ki-Suk and published by Korean Testing Center). 4. School activity record. 5. Sociocratic test. IV. The following conclusions were derived from the study 1, As compared with normal children, socially-handicapped ones have, in many cases, larger number of siblings, their families belong to lower economic bracket: their parents were indifferent to their children, and their mothers were less educated. 2. As compared with normal children, socially-handicapped ones are emotionally unstable, although they are the same as normal children in their sense of dominancy, responsibility, sociality, and confidence. 3. As compared with normal children, socially-handicapped ones are tardy in their learning, although they are almost the same as normal ones in their intelligence development. 4. As compared with normal children, socially-handicapped ones make friends more easily with pupils of other classes and schools rather than those of their own class or school.

• Journal of Microbiology and Biotechnology
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• 제26권5호
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• pp.918-927
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• 2016

Cryptococcus neoformans is a life-threatening pathogenic yeast that causes devastating meningoencephalitis. The mechanism of cryptococcal brain invasion is largely unknown, and recent studies suggest that its extracellular microvesicles may be involved in the invasion process. The 14-3-3 protein is abundant in the extracellular microvesicles of C. neoformans, and the 14-3-3-GFP fusion has been used as the microvesicle's marker. However, the physiological role of 14-3-3 has not been explored. In this report, we have found that C. neoformans contains a single 14-3-3 gene that apparently is an essential gene. To explore the functions of 14-3-3, we substituted the promoter region of the 14-3-3 with the copper-controllable promoter CTR4. The CTR4 regulatory strain showed an enlarged cell size, drastic changes in morphology, and a decrease in the thickness of the capsule under copper-enriched conditions. Furthermore, the mutant cells produced a lower amount of total proteins in their extracellular microvesicles and reduced adhesion to human brain microvascular endothelial cells in vitro. Proteomic analyses of the protein components under 14-3-3-overexpressed and -suppressed conditions revealed that the 14-3-3 function(s) might be associated with the microvesicle biogenesis. Our results support that 14-3-3 has diverse pertinent roles in both physiology and pathogenesis in C. neoformans. Its gene functions are closely relevant to the pathogenesis of this fungus.

• Journal of Chest Surgery
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• 제33권3호
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• pp.240-244
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• 2000

Background: Neuroblastoma is the third most common malignancy of chidhood, and is the most common mediastinal mass in children under the age of 2 years. However, the results of surgical treatment have been seldomly reported in Korea. Therefore, we analyzed the results of surgical treatment in children with neuroblastoma and its influencing factors. Material and Method: We studied the clinical characteristics and prognosis of 12 children, 11 makes and 1 female, whose primary thoracic neurobalstomas or ganglioneuroblastomas were diagnosed and operated between 1977 and 1997. Men age at presentation was 29.9 months. Result: Respiratory symptoms were the modes of performed in 9 patients. Complete excision, partial excision, and biopsy only were performed in 9, 2, and 1 patients respectively. Ten patients of thoractic neuroblastomas survived (83.3%) during follow-up period. Conclusion: The postoperatve 5-year survival of thoracic neuroblastoma was 76.4% and the prognosis was related to the stage of neuroblastoma. We suggest that complete resection should be considered as preferential method in the treatment of thoracic neuroblastoma in children, especially with early stage.

• Childhood Kidney Diseases
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• 제24권2호
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• pp.138-142
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• 2020

Atypical hemolytic uremic syndrome (aHUS) is an extremely rare and life-threatening disorder. Typical HUS is often caused by Shiga toxin-positive Escherichia coli, while aHUS is caused by dysregulation of the alternative pathway of the complement system in association with genetic abnormalities or development of autoantibodies. Eculizumab, a humanized anti-complement 5 monoclonal antibody, is recommended for the treatment of aHUS, but its long-term safety and efficacy in pediatric patients remain under review. In this paper, we report a pediatric case of aHUS with anti-complement factor H autoantibodies, who was treated successfully with eculizumab.

• 한국가족관계학회지
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• 제22권2호
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• pp.99-117
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• 2017

Objectives: The purpose of this study was to explore differences of fathers' and mothers' parenting behaviors, sharing, and stresses by levels of family system functioning in families with young children. Methods: The sample of this study included 1,611 first married couples having at least one child aged under 5 years in the 6th wave of the Panel Study on Korean Children(PSKC). Results: It was found that fathers' cohesion and flexibility were higher than mothers'. It was also found that there were significant differences in fathers' and mothers' parenting behaviors, sharing, and stresses by the level of family system functioning. Conclusions: This study suggested that the family system functioning are related to parenting in families with young children. Further implication were discussed for enhancing family system functioning and parenting behaviors of young children.

• Journal of Preventive Medicine and Public Health
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• 제46권4호
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• pp.173-182
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• 2013

Obesity during childhood is a dominant risk factor for noncommunicable diseases (NCDs), and is itself considered a disease that needs to be treated. Recently, the growth in childhood obesity in Korea has become stagnant; however, two in every ten children are still overweight. In addition, 60% or more of overweight children have at least one metabolic syndrome risk factor. Thus, childhood obesity should be controlled through lifestyle modification. This paper reviews studies of the modifiable risk factors of obesity in Korean children. According to the life-course approach, preschool-aged children (<5 years) are influenced by their parents rather than individual habits because they are under mostly parental care. Elementary school-aged children (6 to 11 years) are affected by overlapping individual and parental effects. This may mean that the establishment of individual behavior patterns begins during this period. The conditions of poor eating habits such as skipping meals, eating out, and high fat intake, along with low physical activity, facilitate increased obesity among adolescents (12 to 18 years). Notably, adolescent girls show high rates of both underweight and obesity, which may lead to the development of NCDs in their offspring. Therefore, the problem of NCDs is no longer limited to adults, but is also prevalent among children. In addition, early intervention offers cost-effective opportunities for preventing NCDs. Thus, children need primary consideration, adequate monitoring, diagnosis, and treatment to reduce the burden of NCDs later in adulthood.

• 혜화의학회지
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• 제7권2호
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• pp.609-620
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• 1999

Over the period between January 1997 and December 1998, herbal medicine was more than three times administered to the patients coming to Na dong gyu's Oriental Medical Clinic on account of the symptom of growth deficiency. According to radiological opinions about the patients providing cooperation for measuring their height and weight as well as their bone age every three months, it was found that the growth plates were not closed. A research was conducted for 200 children randomly selected of patients in prepuberty (they grew by less than 5cm a year before treatment at a age of 12years for female children and 14years for male children). As a result, the following conclusion was drawn: 1. The randomly selected subjects were made up of 116 male and 84 female children in terms of gender. The age direstribution was most 10 to 12 years in 86 children(34.00%), followed by 8-10 years(27.50%) and 12 to 14 years(19.50%). 2. Considering the distribution of sick children's parental height, the fathers of 141 children(70.50%) measured less than 170cm high, the subaverage height, while the mothers of 172 children(86%) measured less than 160cm high, the subaverage height. It was shown that sick childen's height was genetically influenced by their parents. 3. Children patients's weight at a time of birth was most 3.1-3.5kg for 85 children(44%) and less than 2.5kg which came under the range of growth dificiency for 19 children(9.5%). 4. The highest proportian of the children patients with growth dificiency(56.33%) had the symptom of digestive disorders, of which 77 children patients(18.78%) had anorexia, 16.59% of children patients had the high level of respiratory disorders. Both the digestive disorder and the respiratory disorder put together, they had the high rate of 72.92%. Therefore, this indicates that both the digestive disorder and the respiratory disorder have a great effect on children's growth dificiency. 10.74% of chilren patients were shown to have allergic disorders, which indicates that they also exert an effect on growth deficiency. Specifically, 7.07% of the children patients had the high level of obesity, which shows that an excessive uptake of nutrition may rather induce children to have growth dificiency though an appropriate amount of nutritional uptake is necessary. 5. Comparing their bone age and their chronological age, 58 children patients(29.00%) showed that they were the same at the highest percent. 79 children patients(39.50%) showed that thier bone age was lower than their chronological age. And 63 children patients(31.50%) showed that their bone age was higher than their chronological age. 6. As regards the prescription administered to children patients for treating their growth dificiency, Growth tang A related to the kidney, the congenital factor, of the causes for growth dificiency in traditional Oriental Medicine was administered to 108 children patients(54%), whereas the Growth tang B related to the spleen, the acquired factor, was administered to 92 children patients(46%). 7. 116 male children patients with growth dificiency had the average value of growth for one year before treatment, 4.39cm, while 84 female children patients had the average value of growth for one year before treatment, 4.24cm. A total of 200 children had the average value of growth for one year before treatment, 4.33cm. The annual average value of growth in growth curve surveyed by the Korea Pediatrics Society was 5.79cm. Compared to this value, the one year average value of growth for 108 male and female children patients taking Growth tang A was shown be 8.44cm, which indicates a greater growth by 4.12cm(95.37%) in comparison with the average value of growth before treatment, 4.32cm, and a greater growth by 2.65cm(45.77%) compared to 5.79cm, the average value of growth in growth curve surveyed by the Korea Pediatrics Society. Also, the average value of growth before treatment for 92 male and female children patients taking Growth tang B was shown to be 8.47cm, which indicates a greater increase by 4.15cm(96.06%) compared to 4.32cm, the average value of growth before treatment and a greater increase by 2.67cm(46.29%) in comparison with 5.79cm, the average value of growth in growth curve surveyed by the Korea Pediatrics Society. Considering the average value of growth for male and female children patients taking Growth tang A and B, it was shown to be 8.46cm, which indicates a greater increase by 4.14cm(95.81%) compared to 4.32cm, the average value of growth before treatment, and a greater increase by 2.67cm(46.11%) compared to 5.79cm, the average value of growth in growth curve surveyed by the Korea Pediatrics Society.

• Child Health Nursing Research
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• 제5권3호
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• pp.318-327
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• 1999

Oral medication is one of the most frequent treatment in clinical care. and frequently refused by children. Children's refusal spends unuseful time and require nurses'Patience. So this study was attempted to develop token economy Program which Promote children's medication. and to evaluate its' effect to construct the experimental ground. This study was a quasi experimental study under the nonequivalent control group non-synchronized design. The subjects of this study were 48 children who were aged 3-12 years and admitted pediatric ward because of their respiratory disease. Token economy program was consisted of cartoon record paper with stickers which expresses the better medication is taken the more germs die, and gift was given for back up reinforcer. To evaluate this Program. time spent for oral medication was measured six time to both experimental group and control group. and measured the perceived effectiveness of this program by nurses. To determine the effect of the program, the data were analyzed by the SAS 6.12 Program with t-test and mean, standard deviation. The results of this study were as follows: 1 In experimental group, time spent for oral medication was significantly shorter than in control group(t=5.24. p=0.0001). Therefore, the hypothesis of this study was strongly accepted. 2. Nurses perceived this program as an effective one(mean=3.125～3.792). The effectiveness occurred before. during and after medication as well as in parental responses, especially in using verbal dissatisfaction after medication. In conclusion. it was found that the token economy program for admitted children was effective in inducing the children's behavior of oral medication. There was no effectiveness in very highly anxious children Whereas, it is recommended that this program should not be used for such children until they settle down. If the token economy program was made in various situation with creative thinking, it will be very useful nursing measurement, especially in caring for children. To improve the qualify of nursing care, the various programs, which can give joyfulness to stressed patients should be developed.

• 한국안광학회지
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• 제1권1호
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• pp.53-56
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• 1996

유치원 원아 109명 218안을 대상으로 시력 및 조절마비제를 사용하지 않은 상태에서 타각적 굴절이상을 측정한 결과, 만3세의 평균시력이 0.6, 만 4세의 평균시력이 0.7, 만 5세의 평균시력이 1.0으로 나타났다. 이는 일본 어린이와 비교하면 약간 떨어지지만 연령이 증가함에 따라 시력도 발달해가는 경향을 보이고 있다. 굴절이상에 있어서는 혼합난시가 14.7%, 원시 18.8%, 근시 66.5%로 나타났다.