• 한국자기공명학회논문지
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• 제15권2호
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• pp.157-174
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• 2011

Although the use of apodization functions in connection with postprocessing of a 2D NMR spectrum proves improved spectral quality, there is usually a trade-off between resolution enhancement and noise suppression due to a classical "uncertainty principle." In this study, therefore, a mathematical deconvolution technique called "Maximum Likelihood Deconvolution (MLD)" was adopted to achieve the spectral resolution and sensitivity enhancement simultaneously. The MLD technique greatly facilitates visualization and restoration of the genuine spectral information from complex 2D NMR spectra that would be problematic with the conventional apodization/FT processing. In particular, application of the MLD to the 2D-NOE spectrum would be very useful to derive the important proton connectivities, which are essential to achieve elucidating the 3D molecular structure.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2001년도 Proceedings of 2001 Korea-Japan Joint Seminar on Particle Image Velocimetry
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• pp.62-74
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• 2001

Present paper describes the principles of PIV measurement approaching from the analytical view, which enables to explain the general form of principles covering all the PIV measurement, and that gives theoretical basis for its higher measurement performances. The explanation of the measurement principles started from the definition of governing equation in differential form as same as the gradient method, and the integral along the particle path line was executed to show the principle of the correlation method with same basis. The integral processes clearly shows the analytical reason why the correlation peak gives the terminal point of path line, and how the effects of deformation and rotation of fluid appears in the correlation map. These results have no differences from our experiences and understandings of the conventional PIV measurement definition in final form. However, the analytical approach enable to understand those facts a priori, and it makes easy to achieve the innovative higher performances of measurement. Analytical explanation clearly shows the behavior of the residual errors caused by the fluid motion, and it enables to analyze the measurement uncertainty theoretically.

• 한국지구물리탐사학회:학술대회논문집
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• 한국지구물리탐사학회 2008년도 공동학술대회
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• pp.69-72
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• 2008

EZTOMO는 시추공 주시토모그래피 소프트웨어 시스템이다. 이 시스템은 초동발췌, 파선추적, 역산, 오차분석 및 시각화 기능을 보유하고 있다. 이 연구에서는 시스템의 초동발췌 와 역산법을 개선 보완하였다. 초동의 파형정보를 사용한 초동발췌 방법과 초동신호의 S/N(신호 대 잡음비)을 사용한 역산법의 보완이다.

• 터널과지하공간
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• 제24권3호
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• pp.234-242
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• 2014

대심도 시추공사는 불확실성을 가진 공사영향요소가 많고, 시공리스크가 크며, 공사성능관리의 효율화여부에 따라 프로젝트의 경제성에 큰 영향을 미치기 때문에 체계적이고 효과적인 관리가 수행되어야 한다. 특히, 시추공사는 수많은 참여주체가 협업하여 진행되기 때문에, 실시간으로 발생되는 모든 시추정보는 원활하게 공유되어야 효율적인 성능관리가 수행될 수 있다. 본 연구에서는 지열정 설계정보를 활용하여 3차원 설계모델을 작성하였다. 또한, 지열정의 각 구간별로 최적화 설계된 성능제어변수 및 공기에 대한 성능정보의 예측결과를 3차원 모델과 연계하여 4D(3D+time)기반 진도 시각화시스템을 구축하였다. 공정간 선후행 관계 및 각 소요공기를 바탕으로 효과적인 공정 모델을 구축하기 위하여 선후행도형법을 활용하여 정보화 공정네트워크를 작성할 수 있는 모듈을 개발하여 3차원 정보와의 연계효율성을 고려하였다.

• 한국지리정보학회지
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• 제13권4호
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• pp.170-180
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• 2010

지하공간 개발의 증가에 따라 지층단면도 등 다양한 형태로 제공되는 지하공간 정보모델의 신뢰성이 요구되고 있다. 그러나 지반은 근본적으로 불확실하며, 이를 표현하는 정보모델도 자료부족, 해석표준 부재 등의 비통계적 요인과 외부환경 변수라는 통계적 요인으로 불확실성을 가진다. 따라서, 현재의 모델 생성은 고도로 훈련된 전문가에 의해 이뤄지고 있다. 본 연구는 지반공학 전문가의 경험과 지식에서 시맨틱을 추출하고, 이를 온톨로지 모델과 정보량으로 정량화하였다. 정량화한 온톨로지 모델은 군집분석의 클러스터간 거리계산에 적용하여 시맨틱을 고려한 군집분석 방법론을 제안하였다. 본 제안 방법을 실험지역에 적용한 결과 기존 K-Means 방법에 비해 전문가의 해석과 유사한 결과를 도출하였으며, 수작업으로는 어려운 대용량 데이터를 손쉽게 처리하고 3차원 GIS로 가시화가 가능하였다. 본 연구를 통해 지반공학 전문가의 도움 없이도, 그 경험을 고려하면서 대량의 지반정보 데이터를 효과적으로 처리하여 신뢰성 있는 지하공간 정보모델을 생성할 수 있을 것이다.

• Safety and Health at Work
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• 제11권2호
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• pp.127-135
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• 2020

A safe work environment is crucial in high-risk industries, such as construction refurbishment. Safety incidents caused by uncertainty and unexpected events in construction refurbishment systems are difficult to control using conventional safety management techniques. Resilience engineering (RE) is proposed as an alternative to traditional safety management approaches. It presents a successful safety management methodology designed to deal with uncertainty in high-risk work environments. Despite the fact that RE resides in the safety domain, there is no common set of RE indicators to measure and assess resilient in the work environment. The main aim of this research is to explore RE indicators that have been identified as important in developing and assessing the resilient work environment in high-risk industries, particularly in construction refurbishment. Indicators have been attained through a systematic literature review of research and scholarly articles published between the years 2004 and 2019. The literature review explored RE indicators in various industries. Descriptive analysis and co-occurrence-based network visualization were used for data analysis. The findings revealed 28 RE indicators in 11 different high-risk industries. The results show that the four commonly used indicators were: top-management commitment, awareness, learning, and flexibility, all of which have a strong relationship with RE. The findings of this study are useful for stakeholders when making decisions concerning the most important RE indicators in the context of their research or practice as this would avoid the ambiguity and disparity in the identification of RE indicators.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2003년도 제2차 연례학술대회 발표논문집
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• pp.170-177
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• 2003

Gene expression data are the quantitative measurements of expression levels and ratios of numberous genes in different situations based on microarray image analysis results. The process to draw meaningful information related to genomic diseases and various biological activities from gene expression data is known as gene expression data analysis. In this paper, we present a hierarchical clustering method of gene expression data based on self organizing map which can analyze the clustering result of gene expression data more efficiently. Using our proposed method, we could eliminate the uncertainty of cluster boundary which is the inherited disadvantage of self organizing map and use the visualization function of hierarchical clustering. And, we could process massive data using fast processing speed of self organizing map and interpret the clustering result of self organizing map more efficiently and user-friendly. To verify the efficiency of our proposed algorithm, we performed tests with following 3 data sets, animal feature data set, yeast gene expression data and leukemia gene expression data set. The result demonstrated the feasibility and utility of the proposed clustering algorithm.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2004년도 추계학술대회 논문집
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• pp.86-89
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• 2004

One most feasible way to measure the concentration field in the micro-channel is using micro-LIF(Laser Induced Fluorescence) method. However, an accurate concentration field at a given cross plane in a micro-channel has not been successfully achieved so far due to various limitations in the light illumination and fluorescence signal detection. The present study demonstrates a novel method to provide an ultra thin laser sheet beam having five(5) microns thickness by use of a micro focus laser line generator. The laser sheet beam illuminates an exact plane of concentration measurement field to increase the signal to noise ratio and considerably reduce the depth uncertainty. Nile Blue A was used as fluorescent dye for the present LIF measurement. The enhancement of the fluorescent intensity signals was performed by a solvent mixture of water $(95\%)$ and ethanol (EtOH)/methanol (MeOH) $(5\%)$ mixture. To reduce the rms errors resulted from the CCD electronic noise and other sources, an expansion of grid size was attempted from $1\times1$ to 3(3 or 5(5 pixel data windows and the pertinent signal-to-noise level has been noticeably increased accordingly.

• Applied Microscopy
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• 제46권3호
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• pp.134-139
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• 2016

Detailed structural and molecular imaging of intact organs has incurred academic interest because the associated technique is expected to provide innovative information for biological investigation and pathological diagnosis. The conventional methods for volume imaging include reconstruction of images obtained from serially sectioned tissues. This approach requires intense manual work which involves inevitable uncertainty and much time to assemble the whole image of a target organ. Recently, effective tissue clearing techniques including CLARITY and ACT-PRESTO have been reported that enables visualization of molecularly labeled structures within intact organs in three dimensions. The central principle of the methods is transformation of intact tissue into an optically transpicuous and macromolecule permeable state without loss of intrinsic structural integrity. The rapidly evolving protocols enable morphological analysis and molecular labeling of normal and pathological characteristics in large assembled biological systems with single-cell resolution. The deep tissue volume imaging will provide fundamental information about mutual interaction among adjacent structures such as connectivity of neural circuits; meso-connectome and clinically significant structural alterations according to pathologic mechanisms or treatment procedures.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2004년도 Proceedings of 2004 Korea-Japan Joint Seminar on Particle Image Velocimetry
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• pp.65-74
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• 2004

Measurement of concentration distributions of suspended particles in a micro-channel is out of the most crucial necessities in the area of Lab-on-a-chip to be used for various bio-chemical applications. One most feasible way to measure the concentration field in the micro-channel is using micro-LIF(Laser Induced Fluorescence) method. However, an accurate concentration field at a given cross plane in a micro-channel has not been successfully achieved so far due to various limitations in the light illumination and fluorescence signal detection. The present study demonstrates a novel method to provide an ultra thin laser sheet beam having five(5) microns thickness by use of a micro focus laser line generator. The laser sheet beam illuminates an exact plane of concentration measurement field to increase the signal to noise ratio and considerably reduce the depth uncertainty. Nile Blue A was used as fluorescent dye for the present LIF measurement. The enhancement of the fluorescent intensity signals was performed by a solvent mixture of water $(95\%)$ and ethanol (EtOH)/methanol (MeOH) $(5\%)$ mixture. To reduce the rms errors resulted from the CCD electronic noise and other sources, an expansion of grid size was attempted from $1\times1\;to\;3\times3\;or\;5\times5$ pixel data windows and the pertinent signal-to-noise level has been noticeably increased accordingly.