• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.1
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• pp.276-280
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• 2011

This study investigated the activation conditions of pancreatic enzymes from porcine pancreas. Duodenum induced the activation of pancreatic protease and lipase in pancreas. When 10% duodenum was added to pancreatic juice and the mixture was incubated at $30^{\circ}C$ for 90 min or at $25^{\circ}C$ for 4 hrs, the activities of pancreatic protese and lipase reached the peak. When the pancreatin was prepared by sequential process of enzymatic activation at $25^{\circ}C$ for 4 hrs, centrifugation, acetone precipitation and freeze-drying, the specific activities of pancreatic protease, lipase and amylase were 136, 116 and 400 U/mg-protein, respectively. The protease, lipase and amylase activities of the prepared pancreatin were 5.4, 58.0 and 16.0 times higher than those of USP standard, respectively.

• Journal of the Korean Ceramic Society
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• v.44 no.12
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• pp.690-695
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• 2007

Scandia stabilized zirconia (ScSZ) is adapted for electrolyte material of solid oxide fuel cell (SOFC) because of its high ionic conductivity and chemical stability. ScMnSZ1 powder having a composition of $((ZrO_2)_{0.89}(Sc_2O_3)_{0.1}(MnO_2)_{0.01})$ is synthesized by ultrasonic spray pyrolysis (USP) method. Porous ScMnSZ1 powder is obtained by using a pore forming agent. Microstructure and morphology, particle size distribution of porous powder synthesized with 3wt% pore forming agent are investigated. Sintered ScMnSZ1 sample with ground fine powder are also investigated their microstructure and electrical conductivity. The electrical conductivity of sintered ScMnSZ1 samples with ground fine powder was 0.082 S/cm, 0.127 S/cm and 0.249 S/cm at $750^{\circ}C$, $800^{\circ}C$ and $900^{\circ}C$, respectively.

• Physical Therapy Korea
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• v.17 no.2
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• pp.25-32
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• 2010

The purpose of this study was to investigate the most effective and comprehensible method for the assessment of resting scapular position (RSP) and pain level (PL) in unilateral shoulder pain (USP). Fifty volunteers with USP were involved in the study. Resting scapular assessments of the patients' pain sides (PS) and non-pain sides (NPS) were evaluated. The assessment tools for RSP are: 1) sternal notch (SN) to coracoid process (CP) distance 2) 3rd thoracic spinous process (T3S) to posterolateral angle of acromion (PLA) distance 3) scapular index 4) 8th thoracic spinous process (T8S) to inferior angle of scapular (IAS) distance 5) supine measurement of pectoralis minor (PM) distance 6) standing PM distance 7) PM index (PMI) and 8) PM pain. The paired t-test was used to compare PS and NPS in RSP. Pearson correlation analysis was used to confer a relationship between the PL and RSP. The results of this study indicated that: 1) all the variables between the PS and NPS for RSP were statistically significant(p<.05) and 2) the PMI showed the strongest relationship in the correlation analysis between RSP and PL(p<.05, r=.37). Therefore, it can be concluded that there is a relationship between PMI and PL and it is suggested that an assessment tool using PMI to diagnose shoulder pain would be clinically effective.

• Korean Journal of Clinical Pharmacy
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• v.24 no.3
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• pp.219-228
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• 2014

Objectives: This paper was aimed to investigate the adhesion control standards of pain relieving patch (PRP) drugs and to survey it's adverse effects on the skin of patients for safe use of PRP drugs. Methods: In this study, the related documents of PRP drugs of Korea pharmacopoeia (KP), United States pharmacopoeia (USP), Japanese Pharmacopoeia (JP), European pharmacopoeia (EP), and information web sites of the Ministry of Food and Drug Safety (MFDS) were surveyed. Also, the past and current labeling of PRP drugs marketed in the pharmacy was investigated and compared. Results: In KP and JP, the lower limit standard for PRP's adhesion control is established, but the upper limit standard is not designated. In USP and EP, neither the lower nor upper limit standard is established. The main reasons of skin adverse effects are considered as inherent adverse reactions of the applied drugs for PRP. Another reason is involved in patient's medication mistakes related to PRP's adhesion control, respiratory depression of skin according to physical skin closure, and microbial growth, etc. Conclusion: For safe use of PRP drugs, we proposed ensured guidelines like additional instructions of pharmacist's prescription and detailed labeling systems for usage of PRP drugs applied on skin.

• The Journal of the Korea Contents Association
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• v.13 no.11
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• pp.579-586
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• 2013

To see what the promotional movie of the same product, Each concept were respectively constructed for Optimized SNS marketing movie. There are two types of movies. One is the teaser of product design in the form of showing 'Feature Movie' and the other is the 'Viral Movie' presenting USP of the product in parody technique, which can be compared with each others. The two movies show on YouTube, then feedback from viewers were analyzed in detail. As a result, data for view and shares of viral movie showed relatively higher than the feature movie. It means that the viral movie is more effective for marketing since its various elements such as fun, story and visuals are sharable. It makes people more interested and immersed in these contents. Thus, viral movies for SNS marking are distributed to reflect the issue of the time, all the concepts are clear to show what the product is for, and most importantly it can trigger the attention of viewers.

• Membrane Journal
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• v.15 no.4
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• pp.330-337
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• 2005

Water selective silica membranes were prepared fur use as membrane reactor for synthesis of dimethyl ether (DME) by methanol dehydration. Silica membranes formed on a Porous SUS tube by ultrasonic spray Pyrolysis (USP) and chemical vapor deposition (CVD) using tetraethoxysilane (TEOS) as precursor. The CVD-derived membranes formed higher level of trade-off line between water permeance and water/methanol selectivity than that of the USP-derived membranes. The membrane reactor possessing water permeance of $1.2\times10^{-7}\;mol\;{\cdot}\;m^{-2}\;{\cdot}\;S^{-1}\;{\cdot}\;Pa^{-1}$ and water/methanol selectivity of 10 exhibited increase in methanol conversion of about $20\%$ comparing to conventional reactor system. These findings led us to conclude that the dehydration membrane reactor simultaneously separating the water vapour produced in the reaction zone was effective in increasing the reaction conversion.

• Journal of Embryo Transfer
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• v.28 no.4
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• pp.343-348
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• 2013

Cell-free fetal RNA has been highlighted as useful tools for the fetal sex determination or other genetic inherent disorder. However, there is no knowledge about the sex determination using cell free fetal RNA in bovine field. Thus, the present study aimed to evaluate the presence of transcripts of DDX3Y, USP9Y and ZRSR2Y genes in maternal plasma of pregnant cows to determine the sex of the fetus using real-time quantitative polymerase chain reaction assay, and verify its accuracy, sensitivity and specificity compared with the molecular testing and the calf sex at birth. Transcripts of USP9Y and DDX3Y genes were expressed in the all plasma of males and females both the control group and the experimental group. However, ZRSR2Y gene was matched up with the molecular testing and the true sex in control group and has an overall accuracy of 82.6%, a sensitivity of 75%, and a specificity of 100% in experimental group. Therefore, these results indicated that real time PCR technique, as a noninvasive and cost-efficient method, is possible to determination fetal sex in the bovine species using circulating cell free RNA in maternal plasma and especially ZRSR2Y gene could be a good candidate for the RNA based sex determination work.

• Journal of Oriental Neuropsychiatry
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• v.35 no.1
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• pp.37-68
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• 2024

Objectives: This study aimed to systematically review thread-embedding treatment studies for depression, anxiety, and dementia and examine the effectiveness and safety of thread-embedding treatment. Methods: Ten domestic and international search databases were used for study selection, including CNKI, PubMed, CENTRAL, EMBASE, CINAHL, AMED, PsycArticles, RISS, OASIS, and KCI. We included studies that presented diagnostic or appropriate criteria for depression, anxiety, and dementia, and randomized control studies using thread-embedding therapy. We searched papers published until October 10, 2023. Results: Twenty-one studies were selected, of which 11 studies were conducted on depression, nine on dementia, and one on anxiety disorders. The most commonly used acupoint for depression was Gansu (BL18), whereas zusanli (ST36) and fenglong (ST40) were used for dementia. The most commonly used type of thread was 1-0 United States pharmacopeia (USP) and 1 cm for depression and 2-0 USP and 1 cm for dementia. The treatment period for most of the studies was once every 2 weeks and for 8 weeks. Among the included studies, 17 showed significant improvements in depression scales, such as Hamilton depression rating scale and Self rating depression scale, activities of daily living scales, and cognitive function scales, such as Hasegawa dementia scale and Mini-mental state examination. Six studies reported adverse events, and no studies reported significant adverse events. Two studies reported follow-ups. Conclusions: This study presents limited evidence for the effectiveness and safety of thread-embedding therapy for depression, anxiety, and dementia. Well-designed studies are needed to review the clinical efficacy and safety of thread-embedding therapy in the future.

• Journal of Marine Life Science
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• v.5 no.2
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• pp.35-42
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• 2020

17β-estradiol (E₂) is a natural hormone secreted by ovary, and continuously discharged from household and livestock wastewater into aquatic environment. Due to its strong estrogenic activity, it has adverse effects on development and reproduction in crustacean as an endocrine disrupting chemical. Although ecdysteroid signaling pathway play a key role in development in crustacean, little information on transcriptional modulation of ecdysteroid-related genes in response to E₂ is available in small crustacean. Here, we investigated the acute toxicity of E₂ to obtain 24-h LC_x values in the brackish water flea Diaphanosoma celebensis. Time-dependent expression patterns of seven ecdysteroid pathway - related genes (CYP314a1, EcRA, EcRB, USP, ERR, Vtg, VtgR) were further examined using quantitative real time reverse transcriptase polymerase chain reaction (qRT-PCR). As results, 24-h LC₅₀ and LC₁₀ values were 9.581 mg/l and 4.842 mg/l, respectively. The mRNA expression of CYP314a1, EcRA, USP, VtgR was significantly up-regulated at 12 or 24 h after exposure to E₂. These findings indicate that E₂ can affect their molting and reproduction by modulating the expression of ecdysteroid pathway - related in D. celebensis. This study will be useful for better understanding of molecular mode of action of endocrine disrupting chemicals on molting process in small crustacean.

• Journal of Microbiology and Biotechnology
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• v.27 no.4
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• pp.649-659
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• 2017

Extremophilic microorganisms have established a diversity of molecular strategies in order to survive in extreme conditions. Biocatalysts isolated by these organisms are termed extremozymes, and possess extraordinary properties of salt allowance, thermostability, and cold adaptivity. Extremozymes are very resistant to extreme conditions owing to their great solidity, and they pose new opportunities for biocatalysis and biotransformations, as well as for the development of the economy and new line of research, through their application. Thermophilic proteins, piezophilic proteins, acidophilic proteins, and halophilic proteins have been studied during the last few years. Amylases, proteases, lipases, pullulanases, cellulases, chitinases, xylanases, pectinases, isomerases, esterases, and dehydrogenases have great potential application for biotechnology, such as in agricultural, chemical, biomedical, and biotechnological processes. The study of extremozymes and their main applications have emerged during recent years.