• Bulletin of the Korean Chemical Society
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• 제28권5호
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• pp.821-826
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• 2007

Several oxazolidinones, a new class of synthetic antibacterial agents, have shown biological activity against multidrug-resistant gram positive organisms such as staphylococci, streptococci, and enterococci. Previous results of our studies with benzoxazolidinone phosphonate derivatives have demonstrated very low antibacterial activity. In the course of our studies directed towards the discovery of noble antibacterial agents, we have synthesized several new derivatives of oxazolidinone phosphonates prepared efficiently from commercially available amino acids. These compounds are tested for in vitro antibacterial activity and one of the compounds showed promising results allowing us to pursue further studies.

• 수산해양교육연구
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• 제28권6호
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• pp.1673-1682
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• 2016

The paper is the principle of a curriculum, a recent method of teaching-learning in pedagogy, and intended for the exploration of the meaning of which reconstructs curriculum by narrative through practical exploration and narrative being discussed as the form of exploration. To date, Korean education showed an inclination of the traditional paradigm centered thinking and has emphasized the results by the method of scientific investigation. Even a curriculum reconstruction demonstrates documents that produce results without actually demonstrating the actual school setting. With communication one another is becoming increasingly important, we need the conversion of cognitive thinking that can express dilemma, contradictions, and complexities of the human world of which unexplainable by traditional paradigm mindset. Ultimately, the exploration of the direction that reflects a series of verbal, symbolic, and spiritual activities, which analyze lives of students, understanding and composing the meaning by using narrative, which talks about the experience of the human world in curriculums, is an important task for us.

• 한국지반환경공학회 논문집
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• 제7권2호
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• pp.55-66
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• 2006

미국의 기존 고속도로인 LA-1 은 허리케인 대피 및 석유산업 등과 같은 수송수단에 대한 증가하는 지역적 요구를 해소하기 위해 교체되어야 할 필요가 있다. LA-1 고속도로 28km 구간은 습지를 가로지르며 예민한 지반으로 이루어져 있다. 본 지역에 대한 시료채취, 시료의 교란 그리고 시험 과정에서 있을 수 있는 고유의 오류들을 줄이기 위해 방대한 양의 지반조사 및 정밀한 실내시험을 수행하였으며 VFSF를 이용한 시료 운반은 지반에 대한 보다 정밀한 데이터를 얻을 수 있다.

• 한국안전학회지
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• 제28권1호
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• pp.74-80
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• 2013

This study describes structural reliability analysis of actively-controlled structure for which random vibration analysis is incorporated into the first-order reliability method (FORM) framework. The existing approaches perform the reliability analysis based on the RMS response, whereas the proposed study uses the peak response for the reliability analysis. Therefore, the proposed approach provides us a meaningful performance measure of the active control system, i.e., realistic failure probability. In addition, it can deal with the uncertainties in the system parameters as well as the excitations in single-loop reliability analysis, whereas the conventional random vibration analysis requires double-loop reliability analysis; one is for the system parameters and the other is for stochastic excitations. The effectiveness of the proposed approach is demonstrated through a numerical example where the proposed approach shows fast and accurate reliability (or inversely failure probability) assessment results of the dynamical active control system against random seismic excitations in the presence of parametric uncertainties of the dynamical structural system.

• The Journal of Korean Physical Therapy
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• 제28권3호
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• pp.201-204
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• 2016

Purpose: The purpose of this study was to compare the immediate effects of alternative treatment methods in lowering the blood pressure and pulse of prehypertensive patients. Methods: A total of 48 prehypertensive patients were randomly divided into 4 groups of 12 patients and each group received a different intervention. The control group was made to rest, the heat pack (HP) group received heat pack treatment, the ultrasound (US) group received an ultrasound massage, and the myofascial release (MFR) group received myofascial release. The blood pressure and pulse rate were measured before and after intervention. Results: Following intervention, the patients of the MFR group showed a decrease in systolic pressure, diastolic pressure, and pulse rate. Although blood pressure was similar in all groups, a significant decrease in pulse rate was seen in the MFR group compared to others. Conclusion: The application of MFR was shown to be an effective method for lowering the blood pressure and pulse rate in prehypertensive patients.

• 한국중재학회지:중재연구
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• 제28권3호
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• pp.3-20
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• 2018

Independence and impartiality are the operating core of an arbitration disciplinary mechanism. Due to many factors, illegalities and improper acts in arbitration cases are facts of life in our country, and have greatly damaged the credibility of arbitration. It is necessary for us to perfect the operating mechanism of arbitration discipline from the four pluralistic progressive aspects of disciplining the cause externalization, disciplining the subject duality, the quasi-judicature of disciplinary procedures and the disciplining measures so that the populace can experience fairness and justice in every case. We should perfect the supporting measures such as the strict selection conditions and procedures of arbitrators, improving the quality of the arbitrator team, exploring the management mechanisms and strengthening the evaluation dynamic. An examination is a general investigation and evaluation so as to provide encouragement for being continually engaged as arbitrators, but it does not provide an objective basis of arbitration discipline. It is urgent to perfect the arbitration guarantee system on the basis of meeting the material needs of the arbitrators so as to enhance the sense of professional rank and honour of arbitration.

• Communications for Statistical Applications and Methods
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• 제28권2호
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• pp.171-188
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• 2021

Due to an increased demand for longevity risk analysis, various stochastic models have been suggested to evaluate uncertainly in estimated life expectancy and the associated value of future annuity payments. Recently updated data allow us to analyze mortality for a longer historical period and extended age ranges. This study followed up previous case studies using up-to-date empirical data on Korean mortality and the recently developed R package StMoMo for stochastic mortality models analysis. The suitability of stochastic mortality models, focusing on retirement ages, was investigated with goodness-of-fit, validity of models, and ability of generating reasonable sets of simulation paths of future mortality. Comparisons were made across various types of models. Based on the selected models, the variability of important estimated measures associated with pension, annuity, and reverse mortgage were quantified using simulations.

• Genomics & Informatics
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• 제19권3호
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• pp.28.1-28.4
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• 2021

Since only a small number of patients have a rare disease, it is difficult to identify all of the features of these diseases. This is especially true for patients uncommonly presenting with rare diseases. It can also be difficult for the patient, their families, and even clinicians to know which one of a number of disease phenotypes the patient is exhibiting. To address this issue, during Biomedical Linked Annotation Hackathon 7 (BLAH7), we tried to extract Alexander disease patient data in Portable Document Format. We then visualized the phenotypic diversity of those Alexander disease patients with uncommon presentations. This led to us identifying several issues that we need to overcome in our future work.

• East Asian Economic Review
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• 제28권1호
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• pp.95-140
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• 2024

This study empirically investigates the international transmission of China's uncertainty shocks. It estimates a time-varying parameter Bayesian global structural vector autoregressive model (TVP-BGVAR) using time series data for 33 countries to evaluate heterogeneous international linkage across countries and time. Uncertainty shocks are identified via sign restrictions. The empirical results reveal that an increase in uncertainty in China negatively affects the global economy, but those effects significantly vary over time. The effects of China's uncertainty shocks on the global economy have been significantly altered by China's WTO accession, the global financial crisis, and the recent US-China trade conflict. Furthermore, the effects of China's uncertainty shocks, typically on inflation, differ significantly across countries. Moreover, Trade openness appears crucial in explaining heterogeneous GDP responses across countries, whereas the international dimension of monetary policy appears to be important in explaining heterogeneous inflation responses across countries.

• 대한기계학회논문집A
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• 제39권9호
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• pp.923-928
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• 2015

본 논문에서는 고경도의 재료를 효과적으로 가공하기 위하여 초음파-자기연마 복합가공을 제시하고, 초음파-자기연마 복합가공의 효율성을 검증하기 위해. 실험계획법을 적용하여 각 인자의 영향력을 평가하였다. 그 결과, 기존의 자기연마가공보다 초음파-자기연마가공의 가공효율이 더 높게 나타났으며, 초음파-자기연마 복합가공에서 가장 적절한 주파수는 28kHz 인 것으로 나타났다. 또 표면거칠기에 대한 인자의 영향을 평가하였을 때, 초음파의 진폭이 가장 큰 영향을 미치는 것을 확인하였다. 그러나 $55{\mu}m$ 의 진폭이 적용되었을 때, 자속밀도의 변화에도 불구하고 가공효율이 오히려 떨어지는 것으로 나타났다. 이러한 결과로부터 지나치게 큰 초음파 진폭은 오히려 자기연마가공의 효과를 저하시키는 것임을 알 수 있었다.