• Title/Summary/Keyword: US

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Insecticidal Effect of Cockroach Baits and their Persistent Efficacy Against the German Cockroach, Blattella germanica (바퀴 독먹이제의 살충 효과 및 지속성 검증)

  • Moon, KyungHwan;Kim, Namjin;Kim, Young Ho
    • Korean journal of applied entomology
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    • v.59 no.1
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    • pp.5-13
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    • 2020
  • Cockroaches are a not only nuisance insects but also have medical importance as they mechanically propagate various pathogens. To date, baits have been widely suggested for use in cockroach control. In this study, we investigated the insecticidal effects of three Korean baits-Korea Combat Ultra Slim (K-CUS), Korea Combat Power (K-CP), and Korea Zaps Dual Bait (K-ZDB)-and three US baits-US Combat Source Kill Max (US-CSKM), US Hot Shot MaxAttrax Roach Bait (US-HSM), and US Raid Double Control Small Roach Bait (US-RDC)-on the German cockroach (Blattella germanica). Among the six baits, three (K-CUS, K-CP, and US-CSKM), the main active ingredients of fipronil, showed rapid and strong insecticidal efficacy. In addition, we compared the persistence of the insecticidal effects of K-CUS and K-CP 6 months and 12 months after initial opening. Insecticidal effects of both baits decreased over time, but the mortality rates of cockroaches exposed to 6-month- and 12-month-aged baits were over 90%, suggesting that these baits can maintain their insecticidal effect for at least one year after indoor installation.

Inhibition of Human $CD8^+$ Cytotoxic T Lymphocyte (CTL) -mediated Cytotoxicity in Porcine Fetal Fibroblast Cells by Overexpression of Human Cytomegalovirus Glycoprotein Unique Short (US) 2 Gene

  • Park, K-W.;Yoo, J.Y.;Choi, K.M.;Yang, B.S.;Im, G.S.;Seol, J.G.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.1
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    • pp.20-25
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    • 2009
  • Xenotransplantation of pig organs into humans is a potential solution for the shortage of donor organs for transplantation. However, multiple immune barriers preclude its clinical application. In particular, the initial type of rejection in xenotransplantation is an acute cellular rejection by host $CD8^+$ cytotoxic T lymphocyte (CTL) cells that react to donor major histocompatibility complex (MHC) class I. The human cytomegalovirus (HCMV) glycoprotein Unique Short (US) 2 specifically targets MHC class I heavy chains to relocate them from the endoplasmic reticulum (ER) membrane to the cytosol, where they are degraded by the proteasome. In this study we transfected the US2 gene into minipig fetal fibroblasts and established four US2 clonal cell lines. The integration of US2 into transgenic fetal cells was confirmed using PCR and Southern blot assay. The reduction of Swine Leukocyte Antigen (SLA)-I by US2 was also detected using Flow cytometry assay (FACS). The FACS analysis of the US2 clonal cell lines demonstrated a substantial reduction in SLA-I surface expression. The level (44% to 76%) of SLA-I expression in US2 clonal cell lines was decreased relative to the control. In cytotoxicity assay the rate of $CD8^+$ T cell-mediated cytotoxicity was significantly reduced to 23.8${\pm}$15.1% compared to the control (59.8${\pm}$8.4%, p<0.05). In conclusion, US2 can directly protect against $CD8^+$-mediated cell lysis. These results indicate that the expression of US2 in pig cells may provide a new approach to overcome the CTL-mediated immune rejection in xenotransplantation.

A Study on Awareness and Responses of Korean Textile Firms against Korea-US FTA (한·미 FTA에 대한 한국섬유업체의 인식 및 대응방안에 관한 연구)

  • Ha, Ju-Young;Lee, Hyun-Ok;Ku, Yang-Suk
    • Fashion & Textile Research Journal
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    • v.17 no.6
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    • pp.978-987
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    • 2015
  • This study investigates the awareness levels of Korean textile companies and develops appropriate response plans for the Korea-US Free Trade Agreement. The study also explores practical and realistic directions that the Korean textile industry must initiate. A qualitative study was conducted on 10 individuals for a more in-depth and demonstrative understanding that provide a better awareness on the responses of the textile industry towards the Korea-US FTA. The results of this study are as follows. First, the effect of the Korea-US FTA on the textile industry was insignificant. Second, industry members determined that fabric sectors and specialized fabrics (such as industrial materials and finished clothing products) could realize benefits through the Korea-US FTA. Third, industry members emphasize that the current focus is on FTAs by countries that have solidified their positions as manufacturing and sewing bases for the US and Europe (such as Southeast Asia) and not the Korea-US FTA. Based on results acquired through this study, the response measures to enter the U.S. market are as follows. First, the industry must develop high-performance and high value-adding direct export products suited to the needs of the US market in order to realize the benefits of the Korea-US FTA. Second, the industry and government must cooperate to actively host and participate in overseas trade shows that can actively open sales channels within the US. Third, the self-sustainability of textile companies must be cultivated through continuous and focused government training.

Antioxidant, anti-inflammatory, antibacterial and ovoprotective effects of mixture of Ulmi cortex and Smilacis rhizoma extracts (유백피, 토복령 추출물 혼합물의 항산화, 항염, 항균 및 난소세포 보호효과)

  • Jeon, Sang Kyu;Ahn, Jung Yun;Park, Su Mi;Park, Sun-Dong;Lee, Ju-Hee
    • Herbal Formula Science
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    • v.28 no.1
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    • pp.41-51
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    • 2020
  • Objectives : US extract is a mixture of each extract of Ulmi cortex and Smilacis rhizoma. In this study, we investigated the antioxidant, anti-inflammatory, antibacterial, and ovoprotective effects of US extract in in vitro model to identify potential candidates for improving female reproductive function. Methods : The antioxidant activity of US extract was measured using 1,1-diphenyl- 2-picrylhydrazyl free radical and superoxide anion radical scavenging assays. The anti-inflammatory effect of US extract on lipopolysaccharide (LPS)-stimulated RAW 264.7 cells were determined with a nitric oxide (NO) assay, enzyme linked immunosorbent assays, and western blots analysis. The antibacterial activity of US extract against vaginitis infection microorganisms were determined with disc diffusion and minimum inhibitory concentration assays. The ovoprotective effect of US extract on 4-vinylcyclohexene diepoxide (VCD)-induced ovotoxicity in CHO-K1 cells were evaluated with a cell viability assay. Result : US extract showed good antioxidant capacity and inhibited LPS-induced NO production as well as iNOS and COX-2 expression and secretion of pro-inflammatory cytokine IL-6 without affecting the cell viability. It showed significant clear zones for Staphylococcus aureus and Candida albicans but did not indicate the clear zones for Escherichia coli and Enterococcus faecium. VCD-induced ovotoxicity in CHO-K1 cells was significantly reduced by US extract pre-treatment. Conclusions : These results demonstrate that US extract has antioxidant activity, anti-inflammatory effects on the LPS-stimulated macrophages, antibacterial activity against vaginitis infection microorganisms, and protective effects on the ovarian cells against VCD-induced ovotoxicity. These findings suggest that the US extract can be used as new prescriptions, supplements, functional foods, and cosmetics for improving female reproductive function.

Effects of Therapeutic Ultrasound on Experimental Induced Rectal Sarcoma(CT-26) (실험적으로 유발된 직장종양에 대한 치료적 초음파의 효과)

  • Cheong, Mee-Sun;Oh, Myoung-Hwa;Kim, Gye-Yeop;Kim, Chan-Kyu
    • Journal of Korean Physical Therapy Science
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    • v.11 no.3
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    • pp.5-13
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    • 2004
  • The use of therapeutic ultrasound(US) in humans with malignant neoplasms has been contra-indicated in physical therapy practice. Some studies have shown the results after application of US inhibited of tumor growth but some studies have shown the results facilitated of tumor growth in mouse. The purpose of this study were to determine the effects of US on rectal sarcoma(CT-26) in mouse and to determine the histological change of tumor. Thirty-five female BALB/C mouse, age 6 to 8 weeks received subcutaneous injection of 0.1 105 tumor cells. When tumors grew to 5 mm in diameters, the mouse were randomly assigned to control group(n=7) and high powered continuous US group(n=7) and low powered continuous US group(n=7) and high powered pulsed US group(n=7) and low powered pulsed US group(n=7). The experimental group (four groups) received 10 treatments over a 10-day period of 3 MHz ultrasound. Tumor dimension were measured on days 1(start of treatment), 5(midtreatment), and 10(end of treatment, preexcision and postexcision). Tumors were weighed after excision and the mouse were observated histological change of tumor. All tumors grew larger over time. Mean tumor weights(in grams) and volumes(in cubic millimeters) were 2.063 g and $2729.313\;mm^3$ for the high powered continuous US group 1.881 g and $2428.002\;mm^3$ for the low powered continuous US group 1.730 g and $2381.002\;mm^3$ for the high powered pulsed US 1.673 g and $2289.562\;mm^3$ for the low powered pulsed US group 1.670 g and $2297.333\;mm^3$ for the control group. Ultrasound increased the weight and volume of subcutaneous tumor in mouse. We urge caution in the use of ultrasound in the areas of tumors.

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An Analysis of Citation Counts of ETRI-Invented US Patents

  • Lee, Yong-Gil;Lee, Jeong-Dong;Song, Yong-Il
    • ETRI Journal
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    • v.28 no.4
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    • pp.541-544
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    • 2006
  • From its foundation until 2004, ETRI has registered over 1,000 US patents. This letter analyzes the characteristics of these patents and addresses the explanatory factors affecting their citation counts. For explanatory variables, research team related variables, invention specific variables, and geographical domain related variables are suggested. Zero-altered count data models are used to test the impact of independent variables. A key finding is that technological cumulativeness, the scale of invention, outputs in the electronic field, and the degree of dependence on the US technology domain positively affect the citation counts of ETRI-invented US patents. The magnitude of international presence appears to negatively affect the citation counts of ETRI-invented US patents.

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Economic Policy Uncertainty in the US: Does It Matter for Korea?

  • Lee, Seojin
    • East Asian Economic Review
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    • v.22 no.1
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    • pp.29-54
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    • 2018
  • Using the indicators of economic policy uncertainty developed by Baker et al. (2016), this paper investigates the effects of the US economic policy uncertainty on the Korea economic uncertainty as well as Korea-US foreign exchange risk. The key findings are that: (i) the degree of spillovers of policy uncertainty from the US to Korea is considerable but not comparatively high; (ii) the US policy uncertainty plays a stronger and more consistent role in Korean currency risk than Korea policy uncertainty and other macro variables. It implies that the economic policy uncertainty in the US is an important contributor to Korea-US exchange rates.

Inactivation of Mycobacterium using Ultrasonic and Ultraviolet Sequential Processes (초음파와 자외선 연계공정을 이용한 Mycobacterium 불활성화)

  • Kim, Wangi;Jung, Yeonjung;Yoon, Yeojoon;Lim, Gwanhun;Kim, Jongbae;Kang, Joon-Wun
    • Journal of Korean Society on Water Environment
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    • v.28 no.1
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    • pp.57-62
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    • 2012
  • In this study, the inactivation efficiency of Mycobacterium marinum was evaluated in buffered water (pH 7) using a low pressure ultraviolet (LP-UV) lamp, ultrasonic (US), and UV/US sequential processes. In the UV alone process, 3 log inactivation of the M. marinum was achieved with a UV dose of $120mJ/cm^2$. However, a tailing phase was later observed because M. marinum has a high tendency for cell aggregation. Even though the M. marinum was not inactivated in the US alone process, the hydrophobicity decreased and turbidity increased due to the crumbling of the cell aggregation. Among the candidate processes which were UV alone, US-UV sequential process and UV-US-UV sequential process, the US-UV sequential process showed the highest synergistic effects for M. marinum inactivation. Consequently, US is a very useful process as a UV irradiation pre-treatment to inactivate M. marinum in water.

Economic Policy Uncertainty and Korean Economy : Focusing on Distribution Industry Stock Market

  • Jeon, Ji-Hong;Lee, Hyun-Ho;Lee, Chang-Min
    • Journal of Distribution Science
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    • v.15 no.12
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    • pp.41-51
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    • 2017
  • Purpose - This study proposes the impact of the US and Korean economic policy uncertainty on macroeconomy, and its effect on Korea. The economic policy uncertainty index of the US and Korea is used to represent the economic policy uncertainty on Korean economy. Research design, data, and methodology - In this paper, we collect the eight variables to find out the interrelationship among the US and Korean economic policy uncertainty index of the US and macroeconomic indicators during 1990 to 2016, and use Vector Error Correction Model. Result - The distribution industry stock index in Korea is influenced by the economic policy uncertainty index of the US rather than of Korea. All variables are related negatively to the economic policy uncertainty index of the US and Korea from Vector Error Correction Model. This study shows that the economic policy uncertainty index of the US and Korea has the dynamic relationships on the Korean economy. Conclusions - A higher economic policy uncertainty shows a greater economy recession of a country. Finally, the economic policy uncertainty of the Korea has an intensive impact on Korea economy. Particularly, the economic policy uncertainty of the US has a strong impact on distribution industry stock market in Korea.