• Journal of Preventive Medicine and Public Health
• /
• v.30 no.2 s.57
• /
• pp.279-292
• /
• 1997

The vaccinations of susceptible children and postpubertal females are the major means to prevent congenital rubella syndrome(CRS). Another means for reducing the CRS is therapeutic abortion or fetal monitoring for women who are infected in the first four months of pregnancy. We could not estimate the incidence of CRS in Korea, because there was no surveillance system for rubella and CRS. Nationwide vaccination program for 15months infant had been started early 1980s. So, most women at childbearing age during study period were not received rubella vaccination. We set forth CRS management system for pregnant women in two rural county of Kyonggi province, Korea. In this system, the presence of rubella IgG and IgM antibodies for early pregnant women were examined with MEIA(Microparticle Enzyme Immunoassay) method by IMx automated analyzer $Abbott^(R)$. The infected pregnant women followed up in order to confirm their childrens CRS. This study was carried out from Mu. 1993 to Jun. 1994, and pregnant women examined were 874 persons. The results were summarized as follows. The overall positive .ate of rubella IgG antibody was 94.5%(826/874). The positive rate was significantly increase as the age increased, and reached 100% in pregnant women who were over 35 years old. This results suggest that a meaningful number of women are infected during childbearing years. The geometric mean titer of IgG of sero-positive subjects was significantly declined as the age increased. On the question about history of URI symptoms and rash in pregnancy, 20.7% of respondents checked on URI symptoms with .ash, 13.5% only URI symptoms without .ash, and 65.8% no symptoms. However there was no demonstrable association between the rubella like infection history in pregnancy and the rubella IgG and IgM antibody status. Rubella infection .ate in pregnant women was 0.9%(95% CI 0.4-1.8%). Two of these 8 infected pregnancies were terminated by therapeutic abortion. One of them was not followed. Five babies had no gross anomalies at birth. In Dec. 1996, three of five babies were normal appeared infants. Two of them were not followed. Throughout this study results, we confirmed the need of CRS management system for pregnant women, in Korea.

• Journal of the Korean Society for information Management
• /
• v.19 no.4
• /
• pp.298-319
• /
• 2002

The Semantic Web is a new technology that attempts to achieve effective retrieval, automation, integration, and reuse of web resources by constructing knowledge bases that are composed of machine-readable definitions and associations of resources that express the relationships among them. To have this kind of Semantic Web in place, it is necessary to have the following infrastructures: capability to assign unchangeable and unique identifier (URI) to each resource, adoption of XML namespace concept to prevent collision of element and attribute names defined by various institutions, widespread use of RDF to describe resources so that diverse metadata can be interoperable, use of RDF schema to define the meaning of metadata elements and the relationships among them, adoption of DAML+OIL that is built upon RDF(S) to increase reasoning capability and expressive power, and finally adoption of OWL that is built upon DAML+OIL by removing unnecessary constructors and adding new ones based on experience of using DAML+OIL. The purpose of this study is to describe the central concepts and technologies related to the Semantic Web and to discuss the benefits of metadata interoperability based on XML/RDF schemas and the potential applications of diverse ontologies.

• Journal of Korean Neurosurgical Society
• /
• v.61 no.3
• /
• pp.319-332
• /
• 2018

Germline mutations in cancer causing genes result in high risk of developing cancer throughout life. These cancer predisposition syndromes (CPS) are especially prevalent in childhood brain tumors and impact both the patient's and other family members' survival. Knowledge of specific CPS may alter the management of the cancer, offer novel targeted therapies which may improve survival for these patients, and enables early detection of other malignancies. This review focuses on the role of CPS in pediatric high grade gliomas (PHGG), the deadliest group of childhood brain tumors. Genetic aspects and clinical features are depicted, allowing clinicians to identify and diagnose these syndromes. Challenges in the management of PHGG in the context of each CPS and the promise of innovative options of treatment and surveillance guidelines are discussed with the hope of improving outcome for individuals with these devastating syndromes.

• Proceedings of the Korea Contents Association Conference
• /
• 2009.05a
• /
• pp.283-288
• /
• 2009

Semantic service can be defined as the service providing search API or reasoning API based on ontology and Web Services. It performs a pre-defined task by exploiting URI, classes, and properties. This study introduces a semantic service composition method based on a semantic broker referring ontology and management information of semantic services stored in a semantic service manager with requirements of the user. The requirements consist of input instances, an output class, a visualization type, semantic service names, and property names. This composition method provides dynamically generated semantic service pipelines including composit semantic services. The user can execute the pipelines provided by the semantic broker to find a meaningful semantic pipeline. After all, this study contributes to develop a system supporting human service planners who want to find composit semantic services among distributed semantic services.

• Journal of the Korean BIBLIA Society for library and Information Science
• /
• v.15 no.1
• /
• pp.43-67
• /
• 2004

The purpose of this study is to design semantic web and policy direction for national knowledge and information management. The paper describes all the components needed to accomplish the objective: 1) creating unchangeable and unique identifiers for metadata elements, resources, and ontology classes and properties; 2) recommending active use of XML namespaces; 3) establishing metadata and application profile standards for national integrated searching; 4)developing a metadata registry to promote semantic interoperability among metadata; 5) discussing the need of creating ontologies using W3C OWL and ISO Topic Maps; 6) providing intelligent search services based on metadata; and 7) presenting future directions and tasks of national knowledge and information management.

• Proceedings of the Korean Information Science Society Conference
• /
• 2003.04a
• /
• pp.641-643
• /
• 2003

웹 서버에서 제공하는 문서 자원들은 URL/URI 형식으로 표현되고 있지만, 동적인 서버 환경의 변화로 인해 반드시 해당 자원이 서버에 존재하고 있는 것을 보장할 수 없다. 따라서 본 논문에서는 자원에 대한 신뢰성을 보장하고, 동적인 서버 자원 관리 및 클라이언트의 요청을 처리하는 XML-RPC를 이용한 통합 문서 관리 시스템을 제안하고 모델링 한다. 제안한 시스템은 동적인 서버 자원을 관리하는 미들웨어 시스템과 클라이언트가 서버에 저장시킨 문서에 대한 갱신 정보를 미들웨어 시스템으로 통보하는 서버 시스템으로 구성된다. 모델링 결과, 분산된 서버에 있는 동적으로 변하는 문서들을 효과적으로 저장 관리할 수 있었으며, 현재 운영되고 있는 웹 서버에 적용시킬 수 있어 새로운 웹 서버 구축비용을 절감할 수 있고, XML-RPC 프로토콜을 사용하기 때문에 플랫폼 독립적이면서 데이터 관리가 효율적임을 알 수 있었다.

• Health Policy and Management
• /
• v.17 no.1
• /
• pp.75-93
• /
• 2007

This research purposed to analyse the diversity of the long-term care system based on the dependency/independency of the aged. For this purpose, we divided the long-term care systems to three components; form of benefit, generosity of benefit and delivery system. Form of benefit is whether the benefit is cash or in-kind, and the generosity of benefit is related to the level and coverage of benefit. The last concerned to focus on provider and user selection. According to this, we tried to make an ideal type of long-term care in the perspective of citizenship and consumerism. As a result, we established four types of long-term care system; active citizen type, passive citizen type, latent citizen type, and family dependent type. And we investigated Austria, Sweden, Germany and Korea for each type empirically.

• International Journal of Knowledge Content Development & Technology
• /
• v.3 no.1
• /
• pp.81-95
• /
• 2013

Through a series of precise text handling processes, including automatic extraction of information from documents with knowledge from various fields, recognition of entity names, detection of core topics, analysis of the relations between the extracted information and topics, and automatic inference of new knowledge, the most efficient knowledge base of the relevant field is created, and plans to apply these to the information knowledge management and service are the core requirements necessary for intellectualization of information. In this paper, the knowledge base, which is a necessary core resource and comprehensive technology for intellectualization of science and technology information, is described and the usability of academic information services using it is evaluated. The knowledge base proposed in this article is an amalgamation of information expression and knowledge storage, composed of identifying code systems from terms to documents, by integrating terminologies, word intelligent networks, topic networks, classification systems, and authority data.

• Journal of Chest Surgery
• /
• v.22 no.1
• /
• pp.59-66
• /
• 1989

Coarctation of aorta, a well known congenital cardiovascular defect, can be recognized in the most instances by simple finding of physical examination. This condition shortens life if untreated, but it can be corrected surgically to render the patient functionally normal. It seems relatively rare in Asian. During Six-Year period from January, 1982 through June, 1988, twenty four consecutive operations for the coarctation of the aorta were performed at Yonsei Medical Center. The patients included 14 males and 10 females in the range, 2 months and 34 years old. Associated Cardiac anomalies were patient ductus arteriosus, ventricular septal defect, mitral valve regurgitation, aortic stenosis, double outlet right ventricle, corrected transposition of great vessel, etc. The preoperative main symptoms were frequent URI and dyspnea. Congestive heart failure was the most common symptom at the group younger than 2 year olds. Operative techniques for the coarctation of the aorta were prosthetic patch aortoplasty in 18 patients, resection & vascular graft interposition in 4, resection and end to-end anastomosis in 2. There was no operative death. Four patients had persistent or paradoxical hypertension, and one had postoperative paraplegia.

• Journal of Internet Computing and Services
• /
• v.15 no.1
• /
• pp.29-43
• /
• 2014

The development of NGS technologies, such as scientific workflows, has reduced the time required for decoding DNA sequences. Although the automated technologies change the genome sequence analysis environment, limited computing resources still pose problems for the analysis. Most scientific workflow systems are pre-built platforms and are highly complex because a lot of the functions are implemented into one system platform. It is also difficult to apply components of pre-built systems to a new system in the cloud environment. Cloud computing technologies can be applied to the systems to reduce analysis time and enable simultaneous analysis of massive DNA sequence data. Web service techniques are also introduced for improving the interoperability between DNA sequence analysis systems. The workflow-based middleware, which supports Web services, DBMS, and cloud computing, is proposed in this paper for expecting to reduceanalysis time and aiding lightweight virtual instances. It uses DBMS for managing the pipeline status and supporting the creation of lightweight virtual instances in the cloud environment. Also, the RESTful Web services with simple URI and XML contents are applied for improving the interoperability. The performance test of the system needs to be conducted by comparing results other developed DNA analysis services at the stabilization stage.