• Title/Summary/Keyword: UR

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정보통신시장 개방과 향후 대응방향

  • Kim, Yeong-Tae
    • 정보화사회
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    • s.76
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    • pp.10-13
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    • 1994
  • UR타결에 따른 시장개방은 세계교역질서에서 고립되기를 원치않는 한 피할수 없는 대세이다. 이에 UR타결에 따른 정보통신시장의 개방내용과 향후 대응방향을 제시한다.

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UR 이후의 국제화 과제

  • Yu, Jang-Hui
    • Korea Petroleum Association Journal
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    • no.9 s.139
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    • pp.8-9
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    • 1992
  • 이 자료는 지난 8월 26, 27일 대한상공회의소에서 열린 대외경제정책연구원 주최 UR 정책세미나에서 발표된 내용을 옮긴 것이다. <편집자 주>

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Inhibitory Effect of Uncaria Sinensis on Matrix Metalloproteinase-9 Activity and Human Aortic smooth Muscle Cell migration

  • Kwak, Chang-Geun;Choi, Dall-Yeong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.6
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    • pp.1629-1635
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    • 2006
  • The migration of vascular smooth muscle cells (VSMC) and the production of matrix metallopreteinases-9 (MMP-9) may play a key role in the development of atherosclerosis. In this study, we have more extensively investigated the inhibitory effect of UR on MMP-9 activity and TNF-${\alpha}$ induced human aortic smooth muscle cells (HASMC) migration. The result from gelatin zymography showed that UR inhibited MMP-9 activity in a dose-dependent manner (IC50 = 55 g/ml). In addition, UR strongly inhibited the migration of HASMC induced by TNF-treatment (IC50 = 125 g/ml), although it has very low cytotoxic effect on HASMC (IC50 > 500 g/ml). These results suggest that UR is a potential anti-atherosclerotic agent through inhibition of MMP-9 activity and VSMC migration.

A Case Study on the Local-based Welfare Facilities of Urban Renaissance Agency in Japan by Business Entry System for Stable Living (일본 UR도시기구의 안심주공간사업자참여제도를 통한 지역복지거점시설 정비사례 연구)

  • Yoo, Soon-Seon
    • Journal of the Korean housing association
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    • v.24 no.5
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    • pp.9-16
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    • 2013
  • The purpose of this study is to analyze local-based social welfare facilities to respond to secular change of the UR rental housing estates in Japan. The selected case studies for the analysis are Hibarigaoka, Hamakousien, Turumai UR rental housing estates constructed around 1960's. The analysis was done through UR website, MLIT (Ministry of Land, Infrastructure, Transport and Tourism) and MHLW (Ministry of Health, Labour and Welfare) policy report, and related literature. These case studies are connected with housing policy as well as welfare policy and performed to Stable Living Creation Project by Business Entry System for Stable Living. The types of local-based social welfare facilities are classified by welfare corporation and medical corporation. The results are as follows: 1) The implementation of cooperative and participative system not only the private sector (welfare and medical Corporation, etc.) but also the public (MLIT, MHLW, UR Renaissance Agency, Local government, etc.). 2) Repurposed of land through rent and transfer of land for local-based social welfare facilities in the process of housing stock renewal utilization. 3) The pursue of regional revitalization through attached to multi-generation facility or local community space for elderly in local-based social welfare facilities.

Rapidly quantitative detection of Nosema ceranae in honeybees using ultra-rapid real-time quantitative PCR

  • Truong, A-Tai;Sevin, Sedat;Kim, Seonmi;Yoo, Mi-Sun;Cho, Yun Sang;Yoon, Byoungsu
    • Journal of Veterinary Science
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    • v.22 no.3
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    • pp.40.1-40.12
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    • 2021
  • Background: The microsporidian parasite Nosema ceranae is a global problem in honeybee populations and is known to cause winter mortality. A sensitive and rapid tool for stable quantitative detection is necessary to establish further research related to the diagnosis, prevention, and treatment of this pathogen. Objectives: The present study aimed to develop a quantitative method that incorporates ultra-rapid real-time quantitative polymerase chain reaction (UR-qPCR) for the rapid enumeration of N. ceranae in infected bees. Methods: A procedure for UR-qPCR detection of N. ceranae was developed, and the advantages of molecular detection were evaluated in comparison with microscopic enumeration. Results: UR-qPCR was more sensitive than microscopic enumeration for detecting two copies of N. ceranae DNA and 24 spores per bee. Meanwhile, the limit of detection by microscopy was 2.40 × 104 spores/bee, and the stable detection level was ≥ 2.40 × 105 spores/bee. The results of N. ceranae calculations from the infected honeybees and purified spores by UR-qPCR showed that the DNA copy number was approximately 8-fold higher than the spore count. Additionally, honeybees infected with N. ceranae with 2.74 × 104 copies of N. ceranae DNA were incapable of detection by microscopy. The results of quantitative analysis using UR-qPCR were accomplished within 20 min. Conclusions: UR-qPCR is expected to be the most rapid molecular method for Nosema detection and has been developed for diagnosing nosemosis at low levels of infection.

Hepatoprotective Effect of Uncaria rhynchophylla on Thioacetamide-Induced Liver Fibrosis Model

  • Choi, Jeong Won;Shin, Mi-Rae;Lee, Ji Hye;Roh, Seong-Soo
    • Biomedical Science Letters
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    • v.27 no.3
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    • pp.142-153
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    • 2021
  • Liver fibrosis is a wound-healing response to chronic liver injury, which is caused by the continuous and excess deposition of extracellular matrix (ECM). The aim of this study is to investigate whether Uncaria rhynchophylla water extract (UR) can ameliorate thioacetamide (TAA)-induced liver fibrosis. The liver fibrosis model was induced on C57BL/6 mice by intraperitoneal injection with TAA three times a week for 8 weeks. UR (200 mg/kg) or silymarin (50 mg/kg) was administered orally daily for 8 weeks. Biochemical analyses including AST, ALT, MPO, and Ammonia levels were measured in serum. In the mice liver tissues, western blot and histological staining were analyzed. As a result, UR dramatically reduced the levels in serum AST, ALT, MPO, and Ammonia levels. UR treatment regulated NADPH oxidase factors expression, and antioxidant enzymes except for GPx-1/2 were significantly increased via Nrf2 activation. Furthermore, pro-inflammatory mediators, such as COX-2 and iNOS were markedly suppressed through the inhibition of NF-κB activation. Expressions of ECM-related protein including α-SMA and Collagen I were noticeably decreased. The additional histological evaluation confirmed that hepatocyte damage and collagenous fiber accumulation were attenuated. Taken together, these data suggest that UR possessed hepatoprotective effects in TAA-induced liver fibrosis via the NF-κB inactivation and Nrf2 activation. Therefore, UR may act as a potential therapeutic drug against liver fibrosis.

The Effect of UR on Chestnut Growers (우루과이 라운드(UR)가 밤 재배농가에 미치는 영향)

  • Choi, Kwan;Han, Sang Yeol;Woo, Tae Myung;Sung, Kyu Chul
    • Journal of Korean Society of Forest Science
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    • v.81 no.3
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    • pp.255-262
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    • 1992
  • Urguay Round(UR) has lots of implication in the forest product market as well as the other sectors of the economy. Chestnut, one of the major forest product in Korea, would be affected by free trade resulting from the agreement on UR. To establish effective policy measures dealing with negative effects of free trade, if any, the effect of UR on producers should be figured out. In this contest, the purposes of this study are (1) estimating the demand, supply and its price functions of this market and (2) forecasting the effect of UR on growers. Using econometric method, demand, supply and price function of this market are estimated. The total amount of yearly money loss of growers due to free trade from 1992 to 2001 are estimated for four different scenarios. In each scenario, it is assumed that the tariffication reduction is 30%, 40%, 50% and 90%. Yearly money loss of chestnut growers at the year 2001 are forecasted such as 14 billion won, 18 billion won, 24 billion won and 25 billion won for the rate of tariffication reduction of 30%, 40%, 50%, and 90%, respectively.

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UR에 대비한 정보산업 분야의 대응방안

  • Korea Database Promotion Center
    • Digital Contents
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    • no.1 s.20
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    • pp.82-98
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    • 1995
  • 지난 '94.12.8일 한국종합전시장(KOEX)에서 제12회 정보산업리뷰 심포지움 'UR에 대비한 정보산업 분야의 대응방안(초고속정보통신망과 MULTIMEDIA를 중심으로)'이란 주제로 심포지움이 열렸다. 이번호에서는 MULTIMEDIA의 세계화 전략을 위한 핵심과제(하드웨어, 소프트웨어, 응용서비스의 핵심과제)를 일부 발췌하여 실었다.

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