• Title/Summary/Keyword: UAP

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UAP56- a key player with surprisingly diverse roles in pre-mRNA splicing and nuclear export

  • Shen, Hai-Hong
    • BMB Reports
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    • v.42 no.4
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    • pp.185-188
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    • 2009
  • Transcripts contain introns that are usually removed from premessenger RNA (MRNA) in the process of pre-mRNA splicing. After splicing, the mature RNA is exported from the nucleus to the cytoplasm. The splicing and export processes are coupled. UAP56 protein, which is ubiquitously present in organisms from yeasts to humans, is a DExD/H-box family RNA helicase that is an essential splicing factor with various functions in the prespliceosome assembly and mature spliceosome assembly. Collective evidence indicates that UAP56 has an essential role in mRNA nuclear export. This mini-review summarizes recent evidence for the role of UAP56 in pre-mRNA splicing and nuclear export.

Effects of F/M ratio on the EPS production and fouling at MBR (MBR에서 F/M비가 EPS 생성 및 fouling에 미치는 영향)

  • Kim, Yun-Ji;Choi, Yun-Jeong;Hwang, Sun-Jin
    • Journal of Korean Society of Water and Wastewater
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    • v.35 no.3
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    • pp.197-204
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    • 2021
  • In MBR, extracellular polymeric substance (EPS) is known as an important factor of fouling; soluble EPS (sEPS) affects internal contamination of membrane, and bound EPS (bEPS) affects the formation of the cake layer. The production of EPS changes according to the composition of influent, which affects fouling characteristics. Therefore, in this study, the effects of the F/M ratio on the sEPS concentration, bEPS content, and fouling were evaluated. The effects of F/M ratio on the amount and composition of EPS were confirmed by setting conditions that were very low or higher than the general F/M ratio of MBR, and the fouling occurrence characteristics were evaluated by filtration resistance distribution. As a result, it was found that the sEPS increased significantly with the increase of the F/M ratio. When the substrate was depleted, bEPS content decreased because bEPS was hydrolyzed into BAP and seemed to be used as a substrate. In contrast, when the substrate is sufficient, UAP (utilization-associated products) was rapidly generated in proportion with the consumption of the substrate. UAP has a relatively higher Protein/Carbohydrate ratio (P/C ratio) than BAP, and this means, it has a higher adhesive force to the membrane surface. As a result, UAP seems like causing fouling rather than BAP (biomass-associated products). Therefore, Rf (Resistance of internal contamination) increased rapidly with the increase of UAP, and Rc (Resistance of cake layer) increased with the accumulation of bEPS in proportion, and as a result, the fouling interval was shortened. According to this study, a high F/M ratio leads to an increment in UAP generation and accumulation of bEPS, and by these UAP and bEPS, membrane fouling is promoted.

THE CONVERGENCE THEOREMS FOR THE AP-INTEGRAL

  • Park, Jae Myung;Lee, Deok Ho;Yoon, Ju Han;Kim, Byeong Moo
    • Journal of the Chungcheong Mathematical Society
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    • v.12 no.1
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    • pp.113-118
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    • 1999
  • In this paper, we study the convergence theorem for the AP-integral based on the condition UAP and pointwise boundedness.

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Ununited Anconeal Process (UAP) in Dog: A Case Report (견(犬)의 주돌기 융합부전증(融合不全症)의 수술치료예(手術治療例))

  • Cho, Kil Hyon
    • Korean Journal of Veterinary Research
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    • v.20 no.2
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    • pp.123-125
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    • 1980
  • Ununited Anconeal Process (UAP) is defined as a disease of young dogs due to developmental abnormality in which there is a seperation of the anconeal process from the diaphysis of the ulna, leading to a front leg lameness and secondary osteoarthritis. A six -year-old German Shepherd dog was presented because of intermittent right front leg lameness. Diagnosis was made of ununited anconeal process with moderate osteoarthritis by radiographic examination. Surgical removal of ununited anconeal process and curettage of osteoarthritic growth within the elbow joint relieved significant clinical signs despite of size and age of the dog.

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Changes in Cell Wall Components, and Solubilization and Depolymerization of Pectin and Neutral Sugar Polymers during Softening of 'Tsugaru' Apples ('쓰가루'사과의 연화에 따른 세포벽성분의 변화와 펙틴 및 중성다당류의 가용화와 분해)

  • Choi, Cheol;Kang, In-Kyu
    • Journal of Life Science
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    • v.16 no.5
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    • pp.834-839
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    • 2006
  • This study was carried out to investigate changes in cell wall components and solubilization and depolymerization of pectin and neutral sugar polymers during softening of 'Tsugaru' apples. Pectic polysaccharides were solubilized in different solvents, distilled-water, 0.05 M CDTA, 0.05 M $Na_2CO_3$, and 8 M KOH, from cell wall materials during fruit softening. The uronic acid contents in distilled-water fraction rapidly increased along with fruit softening at 4 weeks after ambient storage. In the change of non-cellulosic neutral sugars in the cell wall of ‘Tsugaru’ fruits, the major sugar was galactose and arabinose in distilled-water, 0.05 M CDTA and 0.05 M $Na_2CO_3$ soluble fractions, and it was glucose, galactose and xylose in 8 M KOH fraction. Especially the change of galactose contents in distilled-water fraction was increased greatly along with fruit softening. When uronic acid polymers (UAP) and carbohydrate polymers (CP) in distilled-water fraction were filtered and separated using Sepharose CL-2B column, the high molecular UAP and CP were degraded to the low molecular ones from at harvest to softening fruit. Thus, the amount of high molecular polymers were greatly decreased along with fruit softening.

Comparative Analysis of Liver Ultrasound and Fibroscan Tests for Fatty Liver Diagnosis (지방간 진단을 위한 간 초음파와 Fibroscan 검사법의 비교 분석)

  • Kim, Keun-Hee;Ji, Tae-Jeong;Kim, Hyeon-Jin
    • Journal of the Korean Society of Radiology
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    • v.16 no.3
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    • pp.265-271
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    • 2022
  • This study retrospectively analyzed the test results of 441 patients who visited Hospital I in Busan from October 2021 to December 2021 and conducted both mid-term ultrasound and fibroscan tests. The purpose of the study was to investigate the usefulness of fibroscan in inter-fat evaluation by conducting correlation analysis and chi-squared test of inter-fat evaluation using liver ultrasound and fibroscan. As a result of analyzing the correlation between the fatty liver reading result of abdominal ultrasound and Fibroscan UAP, the correlation was found to be r=0.600 and p=0.000. In the inter-provincial evaluation, Fibroscan showed high validity in predicting objective results using inter-provincial values.

Effect of Compaction Methods on the Microstructures and Mechanical Properties of α-Alumina (α-알루미나의 미세구조 및 기계적 성질에 미치는 성형방법의 영향)

  • Baek, Jeong Hyun;Lee, Sung gap;Chun, Myoung Pyo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.32 no.4
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    • pp.333-340
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    • 2019
  • The effects of compaction methods on the sintering density, microstructures, and mechanical properties were investigated in ${\alpha}-alumina$ ceramics. ${\alpha}-Alumina$ powders were granulated with a 10% aqueous solution of polyvinyl alcohol (PVA). Uniaxially pressed (UAP) and cold isostatic-pressed (CIP) samples were prepared by pressing uniaxially at a pressure of 1 ton for 1 min, and isostatically at 200 MPa for 15 min, respectively. Subsequently, both types of samples were sintered at $1,200^{\circ}C$, $1,300^{\circ}C$, $1,400^{\circ}C$, $1,450^{\circ}C$, $1,500^{\circ}C$, $1,550^{\circ}C$, and $1,600^{\circ}C$ at a rate of $5^{\circ}C/min$ for 2 h. The CIP samples were better than the UAP samples for all properties measured, such as the sintering density, Vicker's hardness, and toughness. The CIP sample sintered at $1,400^{\circ}C$ showed the maximum Vicker's hardness and toughness; this may be attributed to the competing effects of a decrease in porosity and the growth of grains with increasing sintering temperature.

Historical study of IFLA (국제도서관협회연맹(IFLA)의 역사적 고찰)

  • 박옥화
    • Journal of Korean Library and Information Science Society
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    • v.9
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    • pp.85-113
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    • 1982
  • The information material in the library or in the information service center is at once its own property and the national resources, so that every citizen in the country has the right to the equal use of it for the development of the country. Library co-operation enables every citizen to use easily and equally the materials in the library. In the informational society of today, owing to the information explosion, the increase in the various user's demand of the information, and the rise of the cost of information material, even the richest and highly advanced country cannot be self-sufficient. Under these circumstances, the international co-operation among libraries seems to be the best way to solve the difficulties of selfsufficiency. Therefore, this paper aims to study the background of IFLA founded in 1927 in order to promote the international library co-operation and its development up to 1970's since its establishment, and, by introducing IFLA's programs of UBC, ISBD, and UAP, to consider the significance of IFLA's contribution to the development of library and librarianship.

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