• 제목/요약/키워드: UAP

검색결과 12건 처리시간 0.027초

UAP56- a key player with surprisingly diverse roles in pre-mRNA splicing and nuclear export

  • Shen, Hai-Hong
    • BMB Reports
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    • 제42권4호
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    • pp.185-188
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    • 2009
  • Transcripts contain introns that are usually removed from premessenger RNA (MRNA) in the process of pre-mRNA splicing. After splicing, the mature RNA is exported from the nucleus to the cytoplasm. The splicing and export processes are coupled. UAP56 protein, which is ubiquitously present in organisms from yeasts to humans, is a DExD/H-box family RNA helicase that is an essential splicing factor with various functions in the prespliceosome assembly and mature spliceosome assembly. Collective evidence indicates that UAP56 has an essential role in mRNA nuclear export. This mini-review summarizes recent evidence for the role of UAP56 in pre-mRNA splicing and nuclear export.

MBR에서 F/M비가 EPS 생성 및 fouling에 미치는 영향 (Effects of F/M ratio on the EPS production and fouling at MBR)

  • 김윤지;최윤정;황선진
    • 상하수도학회지
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    • 제35권3호
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    • pp.197-204
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    • 2021
  • In MBR, extracellular polymeric substance (EPS) is known as an important factor of fouling; soluble EPS (sEPS) affects internal contamination of membrane, and bound EPS (bEPS) affects the formation of the cake layer. The production of EPS changes according to the composition of influent, which affects fouling characteristics. Therefore, in this study, the effects of the F/M ratio on the sEPS concentration, bEPS content, and fouling were evaluated. The effects of F/M ratio on the amount and composition of EPS were confirmed by setting conditions that were very low or higher than the general F/M ratio of MBR, and the fouling occurrence characteristics were evaluated by filtration resistance distribution. As a result, it was found that the sEPS increased significantly with the increase of the F/M ratio. When the substrate was depleted, bEPS content decreased because bEPS was hydrolyzed into BAP and seemed to be used as a substrate. In contrast, when the substrate is sufficient, UAP (utilization-associated products) was rapidly generated in proportion with the consumption of the substrate. UAP has a relatively higher Protein/Carbohydrate ratio (P/C ratio) than BAP, and this means, it has a higher adhesive force to the membrane surface. As a result, UAP seems like causing fouling rather than BAP (biomass-associated products). Therefore, Rf (Resistance of internal contamination) increased rapidly with the increase of UAP, and Rc (Resistance of cake layer) increased with the accumulation of bEPS in proportion, and as a result, the fouling interval was shortened. According to this study, a high F/M ratio leads to an increment in UAP generation and accumulation of bEPS, and by these UAP and bEPS, membrane fouling is promoted.

THE CONVERGENCE THEOREMS FOR THE AP-INTEGRAL

  • Park, Jae Myung;Lee, Deok Ho;Yoon, Ju Han;Kim, Byeong Moo
    • 충청수학회지
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    • 제12권1호
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    • pp.113-118
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    • 1999
  • In this paper, we study the convergence theorem for the AP-integral based on the condition UAP and pointwise boundedness.

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견(犬)의 주돌기 융합부전증(融合不全症)의 수술치료예(手術治療例) (Ununited Anconeal Process (UAP) in Dog: A Case Report)

  • 조길현
    • 대한수의학회지
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    • 제20권2호
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    • pp.123-125
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    • 1980
  • Ununited Anconeal Process (UAP) is defined as a disease of young dogs due to developmental abnormality in which there is a seperation of the anconeal process from the diaphysis of the ulna, leading to a front leg lameness and secondary osteoarthritis. A six -year-old German Shepherd dog was presented because of intermittent right front leg lameness. Diagnosis was made of ununited anconeal process with moderate osteoarthritis by radiographic examination. Surgical removal of ununited anconeal process and curettage of osteoarthritic growth within the elbow joint relieved significant clinical signs despite of size and age of the dog.

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'쓰가루'사과의 연화에 따른 세포벽성분의 변화와 펙틴 및 중성다당류의 가용화와 분해 (Changes in Cell Wall Components, and Solubilization and Depolymerization of Pectin and Neutral Sugar Polymers during Softening of 'Tsugaru' Apples)

  • 최철;강인규
    • 생명과학회지
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    • 제16권5호
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    • pp.834-839
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    • 2006
  • '쓰가루' 사과의 연화동안에 일어나는 세포벽 성분의 변화와 펙틴 및 중성당류의 가용화와 분해 정도를 조사하였다. 과실의 연화단계별로 펙틴다당류들을 증류수, 0.05 M CDTA, 0.05 M $Na_2CO_3$, 8 M KOH를 이용하여 분획하였다. Uronic acid (UA) 함량은 과실의 연화가 진행되면서 증류수 가용성 분획에서는 저장 4주후에 급격히 증가하였다. 각 분획별 비섬유성 중성당의 종류를 보면 증류수, 0.05 M CDTA 및 0.05 M $Na_2CO_3$ 가용성분획에서의 주요 구성당은 galactose와 arabinose였으며, 8 M KOH 가용성분획에서는 glucose, galactose 및 xylose였다. 특히 증류수 가용성 분획에서 과실의 연화가 진행되면서 galactose의 함량이 증가되었다. 그리고 증류수 가용성인 물질을 Sepharose CL-2B를 이용하여 uronic acid polymers (UAP)와 carbohydrate polymers (CP)를 분획한 결과를 보면 고분자의 UAP 및 CP가 수확후 과실의 연화가 진행될수록 저분자화 되었다. 고분자 중합물의 양은 과실이 연화됨에 따라 감소하였다.

지방간 진단을 위한 간 초음파와 Fibroscan 검사법의 비교 분석 (Comparative Analysis of Liver Ultrasound and Fibroscan Tests for Fatty Liver Diagnosis)

  • 김근희;지태정;김현진
    • 한국방사선학회논문지
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    • 제16권3호
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    • pp.265-271
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    • 2022
  • 본 연구는 2021년 10월부터 2021년 12월까지 부산 소재 I 병원을 내원한 환자와 건감검진 대상 중 간 초음파와 Fibroscan 검사를 모두 시행한 441명의 검사 결과지를 후향적으로 분석하였다. 연구 목적은 간 초음파를 이용한 지방간 평가와 Fibroscan을 이용한 지방간 평가의 상관관계분석 및 카이제곱검정을 시행하여 지방간 평가에 있어 Fibroscan의 유용성을 알아보고자 하였다. 복부초음파의 지방간 판독 결과와 Fibroscan UAP의 상관관계 분석 결과 r=0.600, p=0.000으로 나타나 상관관계가 확인되었다. 지방간 평가에 있어서 Fibroscan은 지방간 수치로 하여 객관적인 결과를 예측하는데 높은 타당도를 보였다.

α-알루미나의 미세구조 및 기계적 성질에 미치는 성형방법의 영향 (Effect of Compaction Methods on the Microstructures and Mechanical Properties of α-Alumina)

  • 백정현;이성갑;전명표
    • 한국전기전자재료학회논문지
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    • 제32권4호
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    • pp.333-340
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    • 2019
  • The effects of compaction methods on the sintering density, microstructures, and mechanical properties were investigated in ${\alpha}-alumina$ ceramics. ${\alpha}-Alumina$ powders were granulated with a 10% aqueous solution of polyvinyl alcohol (PVA). Uniaxially pressed (UAP) and cold isostatic-pressed (CIP) samples were prepared by pressing uniaxially at a pressure of 1 ton for 1 min, and isostatically at 200 MPa for 15 min, respectively. Subsequently, both types of samples were sintered at $1,200^{\circ}C$, $1,300^{\circ}C$, $1,400^{\circ}C$, $1,450^{\circ}C$, $1,500^{\circ}C$, $1,550^{\circ}C$, and $1,600^{\circ}C$ at a rate of $5^{\circ}C/min$ for 2 h. The CIP samples were better than the UAP samples for all properties measured, such as the sintering density, Vicker's hardness, and toughness. The CIP sample sintered at $1,400^{\circ}C$ showed the maximum Vicker's hardness and toughness; this may be attributed to the competing effects of a decrease in porosity and the growth of grains with increasing sintering temperature.

국제도서관협회연맹(IFLA)의 역사적 고찰 (Historical study of IFLA)

  • 박옥화
    • 한국도서관정보학회지
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    • 제9권
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    • pp.85-113
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    • 1982
  • The information material in the library or in the information service center is at once its own property and the national resources, so that every citizen in the country has the right to the equal use of it for the development of the country. Library co-operation enables every citizen to use easily and equally the materials in the library. In the informational society of today, owing to the information explosion, the increase in the various user's demand of the information, and the rise of the cost of information material, even the richest and highly advanced country cannot be self-sufficient. Under these circumstances, the international co-operation among libraries seems to be the best way to solve the difficulties of selfsufficiency. Therefore, this paper aims to study the background of IFLA founded in 1927 in order to promote the international library co-operation and its development up to 1970's since its establishment, and, by introducing IFLA's programs of UBC, ISBD, and UAP, to consider the significance of IFLA's contribution to the development of library and librarianship.

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