• Proceedings of the Korean Biophysical Society Conference
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• 2003.06a
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• pp.37-37
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• 2003

We have shown the $Ca^{2+}$-activated chloride current is present in cardiac myocyte in rabbit pulmonary vein (Kim et al., 2002). This current amplitude was increased as [N $a^{+}$]$_{i}$ was increased and we suggested this chloride current may be involve in the spontaneous action potential frequency change. Since this current is activated by the increase of intracellular $Ca^{2+}$, we would like to test what is the inducer of the increase of [C $a^{2+}$]$_{i}$ between a L-type $Ca^{2+}$-current or a reverse mode of N $a^{+}$-C $a^{2+}$ exchange current. White rabbit (1.5 kg) was used and anesthetized with Ketamin (100 mg/kg). Pulmonary vein (PV) was isolated and sleeve area between left atrium and PV was dissected. Using collagenase (Worthington 0.7 mg/cc), single cardiac myocytes were isolated. In the presence of 15 mM of N $a^{＋}$, three steps of voltage pulses were applied (holding potential : -40 ㎷, -80 ㎷ for 50 msec, 30 ㎷ for 5 msec, 10 ㎷ steps from -70 ㎷ to 60 ㎷). The inward and outward tail current was activated after brief 5 msec prepulse. The outward tail current was blocked by the removal of extracellular chloride substituted by glucuronic acid or by a chloride channel blocker, 5 mM 9-AC. But the inward tail current was still remained even though the amplitude was decreased. The reversal potentials were changed to the direction of the change of chloride equilibrium potential ( $E_{Cl}$ ) but the shift of equilibrium potential was not enough to match to the theoretical equilibrium potential shift. In the presence of L-type $Ca^{2+}$ channel blocker, nifedipine 1 uM, inward tail currents were greatly reduced but the outward current tail currents were still remained. In the presence of N $a^{+}$-C $a^{2+}$ exchange current blocker, 10 uM KB-R7943, the inward and outward tail currents were blocked almost completely. We tried to test the $Ca^{2+}$sensitivity of the chloride current with various [C $a^{2+}$]$_{i}$ in pipette solution from 100 nM to 1 uM but we failed to activate $Ca^{2＋}$-activated chloride currents even though the cell became contracted in the presence of 1 uM $Ca^{2+}$. From these results, we could conclude that the increase of [C $a^{2+}$]$_{i}$ to activate the outward $Ca^{2+}$-activated chloride current was mainly induced by the activation of the reverse mode of N $a^{+}$-C $a^{2+}$ exchanger, But for the increase of [C $a^{2+}$]$_{i}$ to activate the inward tail current, L-type $Ca^{2+}$ current may be the major provoking current. Since the cytosolic increase of [C $a^{2+}$]$_{i}$ through pipette solution have failed to activate $Ca^{2+}$-activated chloride current, this chloride current may have very low $Ca^{2+}$ sensitivity or a comparmental increase $Ca^{2+}$ such as in subsarcolemmal space may activate the chloride current. Since there are several reports and models that the increase of $Ca^{2+}$ in subsarcolemmal space would be over several to tens of uM, both possibility may be valid together.uM, both possibility may be valid together.

• Nuclear Engineering and Technology
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• v.41 no.2
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• pp.187-198
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• 2009

In this paper, three power ramp tests performed on high burn-up Re-crystallized Zircaloy2 - UO2 BWR fuel rods (56 to 63 MWd/kgU) within the SCIP project are simulated with METEOR and ALCYONE 3D. Two of the ramp tests are of staircase type up to Linear Heat Rates of 420 and 520 W/cm and with long holding periods. Failure of the 420 W/cm fuel rod was observed after 40 minutes. The third ramp test consisted of a more standard ramp test with a constant power rate of 80 W/cm/min up to 410 W/cm with a short holding time. The tests were first simulated with the METEOR 1D fuel rod code, which gave accurate results in terms of profilometry and fission gas releases. The behaviour of a fuel pellet fragment and of the cladding piece on top of it was then investigated with ALCYONE 3D. The size and the main characteristics of the ridges after base irradiation and power ramp testing were recovered. Finally, the failure criteria validated for PWR conditions and fuel rods with low-to-medium burn-ups were used to analyze the failure probability of the KKL rodlets during ramp testing.

• Safety and Health at Work
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• v.13 no.4
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• pp.500-506
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• 2022

This study evaluated the consistency between two quantitative fit test devices with different methods of ambient aerosol counting. Three types of respirators (N95, half mask, and full facepiece) were worn by 50 participants (male, n = 25; female, n = 25), PortaCount (Pro+ 8038) and MT (05U) were connected to one probe to one mask, and fit factors (FFs) were measured simultaneously with the original and modified protocols. As a result of comparing MT FFs with PortaCount FFs as references and by applying for the pass/fail criteria (FF = 100), the consistency between the two devices for half masks and full facepieces was very high. N95 was somewhat weaker than the two type of respirators in the consistency; however, the correlation between the two devices was very strong (p < 0.0001). The results showed that an FF of 100 as measured by PortaCount was likely to be measured as 75 by the MT. Therefore, when performing the fit test for N95 using the MT and pass level of FF 100, a certain level of adjustment is necessary, whether end-user or putting a scaling factor by manufacturer.

• Journal of Korean Medicine Rehabilitation
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• v.20 no.4
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• pp.105-130
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• 2010

Objectives : The purpose of this study was to assess the statistical methods errors used in the journal of Oriental Rehabilitation Medicine(JORM) and to identify the types of errors in statistical analysis. Methods : We reviewed quantitative articles that were published in the JORM from January 2005 through October 2009. Those were not used by statistical analysis such as literature studies, case study, review articles were not included in this analysis. A total of 296 articles was reviewed. We evaluated the adequacy and the validity of the statistical techniques with our checklist established be modified Lee's checklist, and three statistical evaluators assessed together to minimize bias. Results : Of the 222 articles, 213 were used in inferential and descriptive statistics. Of those 80% of articles adopting descriptive and inferential statistics were detected having statistical errors. One articles used 1.7 statistical method unit generally. Most frequently employed statistics were student t-test, one way ANOVA. pearson correlation analysis, Mann-whitney U test, paired t-test, and chi-square test in their order. However, most frequent statistics having errors were similar in order. The most common statistic errors were as follow: 1. absence of normality test, 2. misuse between paired test and unpaired test, 3. wrong choice of repeated measures analysis without consideration of time variables, 4, increase of Type I error by using inappropriate multiple test, 5. inappropriate application of discrete or categorical data instead of continuous data in correlation analysis, 6. poor consideration of basic consumption in chi-square test, 7. confusion between frequency comparison and average comparison, 8. mentioning the statistical technique without using it. Conclusions : We found various mistake or misuses in the applications of statistical methodologies in the articles published in the JORM. Careful consideration of statistical use and review from the specialist of statistics are warranted for improving the quality of JORM.

• International Journal of Concrete Structures and Materials
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• v.8 no.1
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• pp.43-59
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• 2014

Many bridges are subject to lateral damage for their girders due to impact by over-height vehicles collision. In this study, the optimum configurations of carbon fiber reinforced polymers (CFRP) laminates were investigated to repair the laterally damaged prestressed concrete (PS) bridge girders. Experimental and analytical investigations were conducted to study the flexural behavior of 13 half-scale AASHTO type II PS girders under both static and fatigue loading. Lateral impact damage due to vehicle collision was simulated by sawing through the concrete of the bottom flange and slicing through one of the prestressing strands. The damaged concrete was repaired and CFRP systems (longitudinal soffit laminates and evenly spaced transverse U-wraps) were applied to restore the original flexural capacity and mitigate debonding of soffit CFRP longitudinal laminates. In addition to the static load tests for ten girders, three more girders were tested under fatigue loading cycles to investigate the behavior under simulated traffic conditions. Measurements of the applied load, the deflection at five different locations, strains along the cross-section height at mid-span, and multiple strains longitudinally along the bottom soffit were recorded. The study investigated and recommended the proper CFRP repair design in terms of the CFRP longitudinal layers and U-wrapping spacing to obtain flexural capacity improvement and desired failure modes for the repaired girders. Test results showed that with proper detailing, CFRP systems can be designed to restore the lost flexural capacity, sustain the fatigue load cycles, and maintain the desired failure mode.

• Steel and Composite Structures
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• v.19 no.3
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• pp.735-757
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• 2015

Composite bonding steel plate (CBSP) is a newly developed type of structure strengthened technique applicable to the existing RC beam. This composite structure is applicable to strengthening the existing beam bearing high load. The strengthened beam consists of two layers of epoxy bonding prestressed steel plates and the RC beam sandwiched in between. The bonding enclosed and prestressed U-shaped steel jackets are applied at the beam sides. This technique is adopted in case of structures with high longitudinal reinforcing bar ratio and impracticable unloading. The prestress can be generated on the strengthening steel plates and jackets by using the CBSP technique before loading. The test results of full-scale CBSP strengthened beams show that the strength and stiffness are enhanced without reduction of their ductility. It is demonstrated that the strain hysteresis effect can be effectively overcome after prestressing on the steel plates by using such technique. The applied plates and jackets can jointly behave together with the existing beam under the action of epoxy bonding and the mechanical anchorage of the steel jackets. The simplified formulas are proposed to calculate the prestress and the ultimate capacities of strengthened beams. The accuracy of formulas was verified with the experimental results.

• Journal of the Korea Concrete Institute
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• v.13 no.4
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• pp.321-328
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• 2001

This paper presents the tensile behavior of stud connections installed between reinforced concrete and steel members. Eight specimens are tested to verify the factors influencing the tensile behavior of the connection. Major variables considered in the test are the reinforcement ratios of concrete member and connection details. Test results indicate that the reinforcing bars near stud bolts contribute to the increase of the tensile strength of the member as well as to the reduction of brittle failure. It is shown that C-type or U-type connection has relatively high ductility. From the evaluation on the tensile strength of test results including those of peformed by previous researchers, it was shown CCD (Concrete Capacity Design) method overestimated the strength. In this paper, the reduction factor of 0.75 ø instead of ø is suggested for design purpose of the stud connection.

• Korean Journal of Ecology and Environment
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• v.51 no.2
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• pp.149-159
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• 2018

Twenty-nine wetlands (20 river type and 9 lake type wetlands) in Gyeongsangnam-do were investigated to understand the characteristics of fish assemblages by the wetland type and to suggest management strategies. As a result, $10.3{\pm}4.8$ species were collected from river type wetlands on average (${\pm}SD$) and $9.1{\pm}4.1$ species from lake type wetlands. Thus, there was no significant difference in the number of species between them (Mann-Whitney U test, P>0.05). However, the species that constitute the fish assemblage showed statistically significant differences between the two wetland types (PERMANOVA, Pseudo-F=2.9555, P=0.007). Furthermore, the species that contribute the most to each type of fish assemblage were Zacco koreanus (river type, 28.51%) and Lepomis macrochirus (lake type, 23.21%), respectively (SIMPER). The results of the NMDS analysis using the fish assemblage by place classified the species into three groups (river type, lake type, and others). The current wetland management is only focused on endangered species, but this study shows a difference in fish assemblage by wetland type. Therefore, a management system based information on endemic species, exotic species and major contribution species should be provided. Furthermore, the classification of some types of wetlands based on the present topography was found to be ambiguous, and wetland classification using living creatures can be used as a complementary method. This study has limitations because only two types of wetlands were analyzed. Therefore, a detailed management method that can represent every type of wetland should be prepared through the research of all types of wetlands in the future.

• Women's Health Nursing
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• v.8 no.4
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• pp.538-549
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• 2002

This study was designed to test the effects of a full body massage on uterine contraction, length of labor, type of delivery, and drug intervention for primipara during labor. Data were collected using a quasi-experiment method (nonequivalent control group, pre-post test design) from November 1, 2001 to July 31, 2002. The subjects of this experiment consisted of 28 women in the experimental group and 29 in the control group, out of 57 primipara hospitalized at the U OB & GYN hospital in Inchon. The experimental group was given a 20 minute full body massage for each of the three delivery phases (latent, active, and transition). The control group was given conventional delivery care. Three (3) parameters were analyzed in this experiment. (1) The interval, duration, and strength of uterine contraction, using an electric tocodynamometer (2) The elapsed time for stage 1 and stage 2 labor. (3) The types of deliveries and drug interventions, using postpartum medical records The data collected were analyzed using the repeated measures analysis of variance (ANOVA), t-test, and $x^2$ test of the SPSS program. The results of the experiment are as follows: 1) Uterine contraction interval was significantly reduced (F=3.210, p=.050). Duration of uterine contraction showed significant increase only during the transition phase (t=-2.319, p=.023). Strength of uterine contraction showed no significant difference. 2) Total length of labor was significantly shortened (t=-5.245, p=.000). The length of 1st stage labor was significantly shortened (t=-5.164, p=.000), with latent phase showing (t=-4.709, p=.000), active phase (t=-2.973, p=.005), and transition phase (t=-2.031, p=.047). The length of 2nd stage labor showed no significant difference. 3) The number of natural deliveries were significantly increased ($x^2$=13.127, p=.004). 4) The number of drug interventions were significantly fewer ($x^2$= 4.493, p=.034). In conclusion, this study shows that a full body massage has a significantly positive effect on uterine contraction interval, length of labor, type of delivery, and drug intervention. Therefore, this study suggests that a full body massage be used clinically to help primipara during labor.

• Journal of the Korean Society of Clothing and Textiles
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• v.26 no.3_4
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• pp.402-411
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• 2002

The objective of this study was to investigate sensibility images of Korean traditional motifs cognized by college students in U.S.A. The subjects consisted of 217 male and 351 female undergraduate students. The experimental materials used in this study were 48 stimuli and questionnaires, composed of 7-point semantic differential scales of 15 bipolar adjectives. Twelve motifs selected from 3 groups of Korean motifs were used as motif stimuli. Twelve repeated patterns were constructed from them to be applied on a CAD-simulated dress. The data were analyzed by factor analysis, ANOVA, Duncan's multiple range test. The major finding were as follows: 1. Four dimensions were emerged accounting for the dimensional structure of the images of Korean traditional motifs. These dimensions were ‘quality’, ‘simplicity’, ‘cheerfulnees’, and ‘modernity’. Among them, ‘quality’and ‘simplicity’were the major dimensions. 2. Category, interpretation type, composition type, and application object had significant effects on the images of above-mentioned dimensions. The interpretation type had a significant effect on ‘quality’image, the composition type on ‘cheerful’image, and the application object on ‘modernity’image.