• 대한한방내과학회지
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• 제19권2호
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• pp.81-87
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• 1998

BACKGROUND : Hwabyung is a culturally-related syndrome of Korea diagnostically confounded with somatization, depressive and generalized anxiety disorders, representing typical clinical manifestations of wide range in their severity. METHODS : This clinical study was carried out on 200 inward stroke patients who had stable vital signs and had stayed at least for 10 days after admission. The patients were devided into two groups, hwabyung and non hwabyung group after an interview with an oriental neuropychiatrist. Than we compared the two groups with general characteristics, past history, stroke type, clinical manifestations and serum lipid levels. Also we investigated recent stressors in hwabyung group. RESULTS : The results showed that the incidence of hwabyung was about 28.5% in stroke patients. The greater number of subjects with hwabyung were women in lower educational level. Aphagia were observed more frequently in hwabyung group and verbal disturbance in non-hwabyung group. The most recent stressor of male in hwabyung group was finantial difficulties due to dishonor, unemployment, cheated and so on. As to female, the conflicts with husband or his family were the most recent stressor. As a whole, finantial difficulties were highly ranked as a recent stress in hwabyung group.

• 대한핵의학회지
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• 제17권1호
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• pp.41-53
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• 1983

It is already well known that many factors are involved in maintaining normal blood glucose level. The amount and components of meal are also thought to be some of the factors which affect the blood glucose and insulin levels. It is reported that as for Koreans sugar takes up over 75% out of 2,098 kcal, the average daily calorie intake per adult. It implies that Koreans take a high-sugar diet compared with Westerners who take $40\sim50%$ of sugar out of their total average daily calorie. For the purpose of studying diurnal variations in serum glucose, insulin and C-peptide of normal Korean adults based on ordinary Korean diet, we selceted 13 normal Korean male adults and divided them into two groups, Group I (7 persons) and Group II (6 persons). We put Group I on 3,100kcal and 75% sugar diet, and Group II on 2,100 kcal and 69% sugar diet per day for over 4 days. Serum glucose, insulin and C-peptide were checked every 30 minutes or every hour throughout 24 hours. Results are as follows: 1. As for serum glucose level, in the prep ran dial fasting state in the morning, $mean{\pm}S.D.$ of Group I was $91.1{\pm}8.2mg%$, while that of Group II is $82.5{\pm}4.4mg%$. Both groups showed peaks of increased glucose level at postprandial 1 hour after each meal. The peak returned to the level shown during the fasting state at postprandial 1 hour after breakfast while the relatively high glucose levels were maintained respectively even for 2 or 3 hours.after lunch and dinner. 2. As for serum insulin level, Group showed $mean{\pm}S.D.$ of $14.7{\pm}3.0{\mu}U/ml$ while Group II shows that of $7.0{\pm}2.6{\mu}U/ml$ in the fasting state. Group I particularly showed the largest peak from preprandial a half or one and half an hour to postprandial one hour of lunch, and made relatively small peaks $(47.7{\pm}10.8{\mu}U/ml)$ at postorandial 1 hour after breakfast and dinner. No such large peak was marked in Group II, though it showed relatively similar patterns of peak after each meal. 3. As for C-peptide, in the fasting state, Group I and Group II showed $3.50{\pm}1.85$ and $1.66{\pm}0.53ng/ml$ of $mean{\pm}S.D.$, respectively. Group II showed peaks parallel to those for insulin level. None out of seven in Group I showed expected increase in C-peptide based insulin secretion at a half or one and half an hour before lunch. On the contrary, C-peptide increased in 5 subjects out of seven in Group I at 11:00 p.m. when insulin did not increase. 4. According to the integrated concentration method for a measurement of 24-hour total. insulin secretion rate, the $mean{\pm}S.D.$ of Group I was $76.4{\pm}15.2$ U and that of Group II was $58.6{\pm}21.1$ U. The above results confirm that Koreans, when given ordinary diet of 2,100 kcal and 69%, sugar, show insulin secretion pattern essentially similar to that of Westerners. On the contrary, when they are put on a high-calorie diet of 3,100 kcal a day, 75% of which is sugar, insulin secretion can be increased before lunch without increase in blood glucose. These results implies that insulin secretion can be affected by some other factors. The observation that an increase in C-peptide after 11 : 00 p.m. independent of insulin level supports an assertion that insulin secretion and C-peptide secretion can be thought as being physiologically dissociable, and these changes of diurnal patterns in the levels of serum insulin and C-peptide are thought to be resulted from the large meal and high-carbohydrate diet.

• 대한공간정보학회지
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• 제16권2호
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• pp.17-21
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• 2008

본 연구는 국내에서 경쟁적으로 추진되고 있는 u-City 구축사업의 지원 및 국가경쟁력 강화를 위한 선도적 기술개발을 목표로 진행되고 있는 지능형국토정보기술혁신사업의 일부 내용으로, 새로운 도시환경인 u-City에서의 도시지상시설물 관리 모델을 제시하고자 하였다. 이를 위해 먼저 국내 시설물관리시스템의 발전과정과 국내에서 추진되고 있는 u-City 사업들을 조사함으로써 u-City에서의 도시시설물관리시스템의 방향과 필수요소, 고려사항 등을 도출하였으며, 이를 근거로 u-City에 적합한 도시시설물 관리 모델을 제시하였다.

• 한국정보시스템학회:학술대회논문집
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• 한국정보시스템학회 2005년도 추계학술대회 발표 논문집
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• pp.359-366
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• 2005

As the ubiquitous computing technology (uT) is prevailing, applying uT is more likely to transform the legacy way of doing business to a new way with the goals of ubiquitous computing: strategic use of information resources by using them everywhere, every time, with any devices for any services. These opportunities naturally require the provision to assess the degree of the transformation from the legacy IT-based e-business to the uT-based business. However, research about assessing the degree of u-transformation has been still very few. Moreover, even deciding what is ubiquitous or not is obscure. Hence, this paper aims to propose the methodology for assessing the degree of u-transformation oriented by the teleology of ubiquitous service, which intends to fully make use of uT in creating new business of next generation. Through the literature review, we developed the methodology to check whether the provided service is ubiquitous or not based on the capabilities that technologies have. and then, the methodology developed to assess the technical requirements that the uT should have when the transformation is considered through the focus group interview based on the literature review of the capability. A two-layered approach is introduced to assess not only the level of ubiquity but also the degree of u-transformation.

• 한국컴퓨터정보학회논문지
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• 제12권4호
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• pp.103-110
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• 2007

현재 유비쿼터스 서비스에 대한 국민들의 인지도는 상당한 수준에 이르렀다. 하지만 정작 이러한 u-서비스는 수요자가 아닌 공급자 위주로 이루어지고 있다. 이를 보완하고자 일반인을 대상으로 하여 u-서비스에 대한 온라인 설문조사를 진행하였다. 설문조사는 교통, 보건/의료, 환경/도시관리, 문화/교육, 행정, 산업 분야의 서비스에 대한 필요도를 묻는 5지선다형의 24문항으로 구성되었다. 총 2,463명이 참여하였고, 이들을 연령, 지역, 학력, 성별로 분류하여 각 집단이 원하는 서비스 분야를 연구하였다. 유비쿼터스 서비스에 대한 전반적인 수요는 남성이 여성보다 높았으며, 연령이 많아질수록 높아지는 경향이 있었다.

• 대한수의학회지
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• 제40권1호
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• pp.117-129
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• 2000

This study was carried out to examine proliferative activity and expression of c-myc oncoprotein and p2lras in normal and preneoplastic rat livers induced by an in vivo mid-term chemical carcinogenesis assay. Sixty, six-week-old male specific pathogen free Sprague-Dawley male rats were randomly divided into five groups. Group I was received a single intraperitoneal(IP) dose(200mg/kg) of diethylnitrosamine(DEN). Group 2(10 rats) was operated partial hepatectomy(PH) and Group 3 was received IP(200mg/kg) DEN, fed two weeks later with 500ppm of phenobarbital(PB). Group 4 was received IP(200mg/kg) DEN, fed two weeks later 500ppm(PB) and PH at week 3 after the onset of experiment. While group 5(20 rats) was not treated and used as a control group. All the rats were sacrificed at age 14 weeks except 10 rats from group 5 were sacrificed at the onset of experiment. Livers of all rats were examined for 5-bromo-2'-deoxyuridine(BrdU) incoporation, proliferating cell nuclear antigen(PCNA), silver-binding nucleolar organizer regions(AgNORs) counts per nucleus and expression of c-myc oncoprotein and p21ras. Both the number and area of the preneoplastic lesions were significantly(p<0.01) compared to other groups. A significant(p<0.01) increase in immunoreactive cells were detected in preneoplastic hepatocytes in Groups 3 and 4 by PCNA and BrdU immunohistochemical stain. The number of the positive cells were significantly(p<0.05) lower in normal 14-week-old rats than those of 6-week-old rats. The results showed that proliferative activity of the hepatocytes was increased by treatment with DEN, PH and PB. Meanwhile, AgNORs counts per nucleus were significantly(p<0.05) increased in the preneoplastic hepatocytes of rats in both groups 3 and 4. The expression of c-myc oncoprotein and p21ras were more readily localized within the hepatic preneoplastic lesions such as hyperplastic nodules. Especially, group 4 showed significantly (p<0.05) overexpressed levels compared to groups 1 and 3. These findings suggest that PCNA, BrdU and AgNORs are significantly increased and c-myc oncoprotein and p21ras are significantly overexpressed in hepatic preneoplastic lesions induced by mid-term carcinogenesis. So these parameters can be an effective markers for hepatic prencoplastic lesions.

• 한국식품영양과학회지
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• 제43권1호
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• pp.24-29
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• 2014

본 연구는 구기자와 구기엽 추출물이 난소를 절제한 흰쥐의 체중 증가, 골밀도, 에스트로겐 수용체의 발현에 미치는 영향을 밝히고자 시행하였다. 실험군은 흰쥐 24마리를 가장수술군(Sham군), 난소를 절제한 대조군(OVX군), 난소절제 후 구기자 추출액을 투여한 군(LCF군), 난소절제 후 구기엽 추출액을 투여한 군(LCL군)으로 구분하였다. 8주 후 난소를 절제한 OVX군($330{\pm}5.39g$), LCF군($315{\pm}2.99g$) 및 LCL군($318{\pm}2.06g$)의 체중은 Sham군($281{\pm}1.71g$)에 비하여 증가하였다. 혈청 osteocalcin 활성은 OVX군($107{\pm}3.52ng/mL$)에 비하여 LCF군($444.6{\pm}26.9ng/mL$)과 LCL군($407{\pm}18.9ng/mL$)에서 증가하였다. Alkaline phosphatase의 활성은 OVX군($95{\pm}2.9U/L$)에 비하여 LCF군($108{\pm}2.7U/L$)과 LCL군($407{\pm}18.9ng/mL$)에서 증가하였다. 8주 후 넙다리뼈를 실체현미경으로 관찰한 결과 뼈 기질밀도는 난소절제군에서 감소하였으나, 구기자와 구기엽을 추출액을 투여한 군에서는 뚜렷이 회복되었다. 에스트로겐 수용체의 mRNA 발현은 OVX군에서는 거의 발현되지 않았으나, LCF군과 LCL군에서 뚜렷이 증가하였다. 이상의 결과로 보아 구기자와 구기엽 물추출물이 난소절제에 의하여 유발된 흰쥐의 뼈 기질 회복 또는 손실 지연에 효과가 있다고 할 수 있을 것이다.

• 대한임상검사과학회지
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• 제56권2호
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• pp.125-134
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• 2024

본 연구는 대한민국 성인을 대상으로 대사증후군(metabolic syndrome, MetS) 유·무에 따른 빈혈과 추정 사구체여과율(estimated glomerular filtration rate, eGFR) 및 요 미세 알부민/크레아티닌 비율(urine microalbumin/creatinine ratio, uACR)의 관련성을 평가하기 위하여 2012년 국민건강 영양조사(KNHNES V-3) 자료를 활용하여 20세 이상 성인 4,943명을 대상으로 데이터를 분석하였다. 본 연구에서 몇 가지 중요한 발견이 있었다. 첫째, 비 MetS 그룹에서는 정상군(eGFR≥60 mL/min/1.73 m² 및 uACR<30 mg/g)의 빈혈(남성, 헤모글로빈[hemoglobin, Hb]<13 g/dL; 여성, Hb<12 g/dL)의 발생률에 비하여 감소된 eGFR 그룹(eGFR<60 mL/min/1.73 m²; odds ratio [OR], 3.65; 95% confidence interval [CI], 1.90~7.00) 및 감소된 eGFR+증가된 uACR 그룹(eGFR<60 mL/min/1.73 m² 및 uACR≥30 mg/g, OR, 6.00; 95% CI, 2.61~13.80)의 빈혈 발생률이 높았다. 둘째, MetS 그룹에서는 정상군에 비하여 증가된 uACR 그룹(OR, 2.18; 95% CI, 1.11~4.27), 감소된 eGFR 그룹(OR, 3.73; 95% CI, 1.09~12.75) 및 감소된 eGFR+증가된 uACR 그룹(OR, 18.17; 95% CI, 6.16~53.63)의 빈혈 발생률이 높았다. 결론적으로, 비 MetS 그룹에서는 빈혈은 eGFR의 감소와 관련이 있었고, MetS 그룹에서는 빈혈은 eGFR 감소 및 uACR 증가와 관련이 있었다. 추가적으로, 비 MetS 그룹과 MetS 그룹 모두에서 eGFR의 감소 및 uACR의 증가가 동시에 나타날 때 빈혈의 발생률이 크게 증가하였다.

• Agribusiness and Information Management
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• 제6권2호
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• pp.13-23
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• 2014

The world is in the process of a structural change related to ICT convergence knowledge industries. ICT is leading to the creation of new products and services, and is making our lives more convenient, safer, and more efficient. In advanced countries, many studies have been conducted with the goal of developing new business models converged with ICT, and this is also the case in the food industry. Korea possesses world-leading ICT, and if this ICT is applied to the food industry, a world-class new business model can be developed. The u-Food System, which is in the process of development in Korea, is a next-generation food system that can allow food providers, consumers, and distributors to access various types of information about food products, including traceability, distribution, safety, quality, and freshness, and manage this information. It is a future food system that converges ICT, biotechnology and sensing technology with food. Based on the u-Food System, this paper will introduce the status of current smart quality distribution technologies that converge ICT (such as sensor tag, sensor network, LBS, GIS, and CDMA) with food technologies (such as traceability, quality, distribution management) to manage the safety and quality of fresh food in the distribution process.

• International Journal of Costume and Fashion
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• 제4권
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• pp.47-61
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• 2004

This study analyzed the buying patterns of American and Korean female college students in terms of criteria for clothing selection； store preferences； criteria for store selection； fashion information sources； expressions of customer dissatisfaction； purchasing frequency and motivations for purchasing clothes. The study was implemented through self-administered questionnaires which were back translated for validity. The samples consisted of 730 female college students majoring in the fields related to clothing and textiles： 310 U.S. and 412 Korean students. Likert scales were used for most measures with 1＝never or very unimportant and 5＝always or very important. Data were analyzed by factor analysis, analysis of covariance, Duncans multiple comparison, and t-test. Results are as follows： 1) Design factor was the most important criteria in clothing selection with no differences between country groups. There were, however, significant differences for psychological exhibition factors, practical and economic factors. 2) Both groups preferred specialty and department stores, with department stores more popular in Korea. 3) Merchandise was the most important store selection criterion and fashion magazines and self-experience were rated as the most important information sources for the both groups. 4) Korean group expressed their dissatisfaction with and observable problem with a product before purchase more often than U.S. group, but the U.S. group was more vocal about color loss or shrinkage after care procedures. 5) Some clear differences between the two countries emerged. Marketers targeting American consumers should pay more attention to practicality and service； to Korean consumers more symbolic meaning of products.