• Restorative Dentistry and Endodontics
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• v.34 no.3
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• pp.208-214
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• 2009

The purpose of this study was to compare the dye leakage of MTA (mineral trioxide aggregate) apical plug produced by two orthograde placement techniques (hand condensation technique and ultrasonically assisted hand condensation technique). To simulate straight canal, 60 transparent acrylic blocks with straight canal were fabricated. These transparent acrylic blocks were divided into 2 groups (Group C; hand condensation technique (HC) and Group U; ultrasonically assisted hand condensation technique (UAHC)) of 30 blocks with each MTA application method. Each group was divided into 2 subgroups (n=15) with different canal size of #70 (subgroup C70 and subgroup U70) and #120 (subgroup C120 and subgroup U120). After apical plug was created, a wet paper point was placed over the MTA plug and specimen was kept in a humid condition at room temperature to allow MTA to set. After 24 hours, remaining canal space was backfilled using Obtura II. All specimens were transferred to floral form socked by 0.2% rhodamine B solution and stored in 100% humidity at room temperature. After 48 hours, resin block specimens were washed and scanned using a scanner. The maximum length of micro leakage was measured from the scanned images of four surfaces of each resin block using Photoshop 6.0. Statistical analysis was performed with Mann-Whitney U test. Group U of UAHC had significantly lower leakage than Group C of HC in #70-size canal (subgroup U70) (p<0.05).

• The Korea Journal of Herbology
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• v.21 no.4
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• pp.11-17
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• 2006

Objectives : The aim was to study experimentally the effects of YUKWOOLTANG(li${\`{u}}$y${\`{u}}$-t${\={a}}$ng; YWT) induced by sodium levothyroxine. Methods : Spargue-Dawley rats were separated into four groups. Except normal group, the other three groups were treated with sodium levothyroxine $32{\mu}g$/200g for 5 days. Among the three groups, two except one(as control group) were treated YWT extract separately(sample A:75mg/200 g, sample B: 150mg/200 g ). T3-uptake, T3, T4, r-TSH, total cholesterol, total protein change in the serum of rats were measured after medication of solid extract of YWT. Results : As a result of this study, in the serum T3-uptake content, sample A showed significant decrease in comparison with control group, but sample B group did not show significant decrease. 2. In the serum T3 content, sample B showed significant decrease in comparison with control group. In the serum T4 content, YWT showed significant decrease in comparison with control group. The serum r-TSH was shown with valuable increase in sample B of YWT. The serum total cholesterol was not shown with valuable increase in YWT. The serum total protein was shown with valuable increase in YWT. Conclusion : These results suggest that YWT is effective to cure Hyperthyroidism.

• Korean Journal of Adult Nursing
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• v.25 no.5
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• pp.539-548
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• 2013

Purpose: The purpose of this study was to investigate the effect of supplemental vitamin D on the physiological indices, muscle mass, and physical functions of aged women. Methods: A non-equivalent pretest-posttest design was used. The participants were 65 elderly women with low serum vitamin D levels. This study was conducted for 12 weeks. The experimental group (n=34) received vitamin D and regular exercise whereas the control group (n=31) received only regular exercise. The data were analyzed by the IBM PASW Statistics (SPSS) 19.0 program. Results: Serum vitamin D (U=0.00, p<.001), parathyroid hormone (U=99.50, p<.001) and calcium (U=250.50, p<.001) levels were significantly increased in the experimental group after the intervention. The experimental group showed significantly increased scores of muscle mass, strength, physical balance, and gait compared to those of the control group. Conclusion: Vitamin D supplementation improved physiological indices, muscle mass, and physical functions. In addition, this program may help to prevent disorders of the musculoskeletal system in aged women.

• Phonetics and Speech Sciences
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• v.4 no.3
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• pp.161-169
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• 2012

The purpose of this study was to investigate the characteristics of speech intelligibility of spontaneous speech and the vowel space parameters in patients with Parkinson's disease. Ten PD patients (M=5, F=5) and a corresponding control group of ten normal adults participated in this study. Firstly, subjects were asked to tell a story about their hometown and youth in order to analyze speech intelligibility. Secondly, the subjects were also asked to repeat four vowels (/a/, /i/, /u/, /e/) five times in order to compare their vowel spaces. The results were as follows: (1) the speech intelligibility of the PD group was lower than that of the control group. (2) Four parameters including vowel area, vowel articulatory index, formant centralization ratio, F2i/F1u ratio were significantly different in each group. For instance, vowel area and F2 ratio were wider and higher, respectively. As a result, a decrease in speech intelligibility of patients with PD is likely to show different types of errors from the normal group. The results of this research are meaningful in a sense that they could provide the objective standard of speech intelligibility and vowel space parameters.

• The Journal of Korean Medicine
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• v.44 no.2
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• pp.34-44
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• 2023

Objectives: The purpose of this research was to find out the efficacy of Castanea crenata Inner Shell (CCIS) distilled herbal medicine on the skin by comparing the difference effect between only simple distilled water and the CCIS distilled herbal medicine application after MTS (microneedle therapy system) treatment. Methods: The present author performed once a week and total 4 times of MTS treatment. The treatment time took about 5~10 minutes and the depth of the needle was adjusted according to the participant's skin condition. In the control group, simple distilled water was applied after MTS and in the experimental group, CCIS distilled herbal medicine was applied. One week after each treatment, the change of skin condition was measured. Two weeks after the end of the clinical trial, the skin condition was checked again. Results: In the case of the test group, there was a significant decrease in pore size and there was a significant increase in U-zone oil, skin tone and elasticity. The test group using distilled herbal medicine showed a significant effect on facial skin compared to the control group using only simple distilled water. Conclusion: Distilled herbal medicine showed an effective action on facial skin. In the case of CCIS distilled herbal medicine, it was found to have a significant effect on U-zone oil content, skin tone, pores, and skin elasticity.

• Restorative Dentistry and Endodontics
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• v.33 no.2
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• pp.90-97
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• 2008

The purpose of this study was to evaluate the effect of passive or active application of primer and coat times of bond on the shear bond strength when a self-etching primer adhesive (Clearfil SE Bond) was applied to enamel surface. Crowns of sixteen human molars were selected. Buccal and lingual enamels of crowns were partially exposed and slabs of 1.2 mm thick were made. They were divided into one of four equal groups (n = 8). Group 1: passive application of Primer and 1 coat of Bond, Group 2: active application of Primer and 1 coat of Bond, Group 3: passive application of Primer and 2 coats of Bond, Group 4: active application of Primer and 2 coats of Bond. Clearfil AP-X was bonded to enamel suface of each group using Tygon tubes. The bonded specimens were subjected to microshear bond strength (uSBS) testing with a crosshead speed of 1 mm/min. The results of this study were as follows; 1. The uSBS of Group 1 was the lowest among groups and the uSBS of Group 4 was the highest. 2. There was not statistically significant interaction between enamel uSBS by application method of Primer and coat time of Bond (p > 0.05). 3. There was not statistically significant difference between enamel uSBS by passive and active application of Primer (p > 0.05). 4. There was statistically significant difference between enamel uSBS by one- and two-coat of Bond (p < 0.05).

• Food Science and Biotechnology
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• v.14 no.1
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• pp.99-101
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• 2005

The effect of treatment with pine needle oil upon rat hepatocytes exposed to alcohol was investigated. The body weight gain, ratio of liver and kidney to body weight, and serum biochemistry of rats administered both alcohol and pine needle oil were compared to control rats treated with alcohol alone. Normal untreated control rats, negative control rats with ethanol treatment, positive control rats with both alcohol and the commercially available hangover cure solution (HCS) treatment and the test group with both alcohol and pine needle oil treatment exhibited aspartate aminotransferase (AST) levels of $84.43{\pm}47.88\;U/L$, $254.57{\pm}463.20\;U/L$, $70.29{\pm}12.60\;U/L$ and $67.00{\pm}5.06\;U/L$, respectively, and cholesterol levels of $95.71{\pm}6.86\;mg/dl$, $113.80{\pm}38.19\;mg/dl$, $91.57{\pm}6.30\;mg/dl$ and $82.29{\pm}4.98\;mg/dl$, respectively. Alanine aminotransferase (ALT) levels were $44.00{\pm}9.04\;U/L$ in normal untreated control rats, increased to $215.43{\pm}428.93\;U/L$ with the administration of ethanol, but interestingly were significantly reduced to $37.83{\pm}6.57\;U/L$ in the test group (p<0.05). Triglyceride (TG) levels were $39.57{\pm}8.62\;mg/dl$ in normal untreated rats, increased to $73.71{\pm}61.20\;mg/dl$ in rats administered alcohol, but were reduced to $26.14{\pm}4.82\;mg/dl$ in the test group (p<0.0l). The pine needle oil treatment significantly reduced the levels of AST, ALT and TG compared to the control rats. These results indicate that pine needle oil can positively mediate the effects of alcohol on hepatocytes and general liver functions.

• The korean journal of orthodontics
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• v.53 no.4
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• pp.241-253
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• 2023

Objective: To evaluate the following null hypothesis: the skeletal and dentoalveolar expansion patterns in the coronal and axial planes are not different with two different types of microimplant-assisted rapid palatal expansion (MARPE) systems. Methods: Pretreatment (T0) and post-MARPE (T1) cone-beam computed tomography (CBCT) images of 32 patients (14 males and 18 females; mean age, 19.37) were analyzed. We compared two different MARPE systems. One MARPE system included the maxillary first premolars, maxillary first molars, and four microimplants as anchors (U46 type, n = 16), while the other included only the maxillary first molars and microimplants as anchors (U6 type, n = 16). Results: In the molar region of the U6 and U46 groups, the transverse expansion at the midnasal, basal, alveolar, and dental levels was 2.64, 3.52, 4.46, and 6.32 mm and 2.17, 2.56, 2.73, and 5.71 mm, respectively. A significant difference was observed in the posterior alveolar-level expansion (p = 0.036) and posterior basal-bone-level expansion (p = 0.043) between the groups, with greater posterior skeletal and alveolar expansion in the U6 group. Conclusions: Compared with the U46 group, the U6 group showed greater posterior expansion at the alveolar and basal-bone levels, with an almost parallel split. Both groups showed a pyramidal expansion pattern in the coronal view.

• Phonetics and Speech Sciences
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• v.2 no.4
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• pp.229-238
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• 2010

This study investigates the differences in acoustic parameters in vowel space across hearing loss, gender and vowels. The parameters include F1, F2, Euclidean Distance between vowels, and vowel triangular area comprised of /i/, /a/ and /u/. For this study, 20 hearing-impaired and normal hearing adults as a control group were asked to read 7 Korean vowels (/a, $\wedge$, o, u, w, i, $\varepsilon$/). Subjects' readings were recorded by NasalView and analyzed by Praat. Results showed that F1 were significantly higher in the hearing impaired group than in the normal hearing group, higher in the female group than in male group, and higher in low vowels than in high vowels. And the means of F2 was significantly higher in the hearing impaired group than in normal hearing group, higher in high vowels than in low vowels, and there was no difference between male and female group. Secondly, Euclidean distance between vowels was significantly shorter in the hearing-impaired group than in the normal group. Finally, acoustic vowel space area was significantly smaller in the hearing-impaired group than in the normal hearing group. The hearing-impaired group showed that front vowels tended to be backed and back vowels to be fronted.

• The korean journal of orthodontics
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• v.26 no.4
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• pp.359-371
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• 1996

The purpose of this study was to investigate the changes about the cellular activity on DNA synthesis in the periodontal ligament of dog, in which experimental tooth movement was performed. A control and 5 experimental dogs, one and half year in age, were studied. Light force (50-75g) was applied by placing open-coil spring between left mandibular premolars ; heavy force (250-300g), between right mandibular premolars. Experimental dogs were sacrificed after infusion of bromodeoxyuridine(BrdU), at 12 hours, 1, 3, 7 and 14 days after force application, respectively. And the histologic and the immunohistochemical evaluation were performed on the obtained periodontal tissue around mandibular premolars, using anti-romodeoxyuridine antibody, which can indicate proliferating cells. The results were as follows: 1. The tearing of periodontal ligament and the vascular dilatation at tension side were observed in 12 hours, increasing until 3 days. After then it decreased; Such a finding was more evident in heavy force group than in light force group. 2. The hyalinization of the periodontal ligament and the activity of osteoclast at pressure side were observed in 12 hours, increasing until 3 days. But from 7 days on, it decreased; Such a finding was more evident in heavy force group than in light force group. 3. The BrdU expression in the control group was positive, mainly in the oral epithelium and the fibroblasts in the periodontal ligament, but negative in bone cells in periodontal ligament. 4. The BrdU expression in the experimental group was more positive in tension side than in pressure side; The expression was a little more positive in the periapical area than in the cervical area of tooth. 5. The BrdU expression in light force group was the highest in 1 day, after which it decreased; In heavy force group, it was the highest in 12 hours, after which it decreased. But in 14 days, there was no difference between the experimental group and control group.