• Title/Summary/Keyword: U/F

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A Restrictive Virus Tropism, Latency and Reactivation of Pseudorabies Virus Following Irreversible Deletion of Bsrl Restriction Site in the Thymidine-kinase Gene

  • Mohd Lila Mohd Azmi;Zeenathul, Nazariah-Allaudin;Abdel-Wahid Saeed Ali;Che Abdul Rahim Mohamed;Kamarudin, Awag-Isa
    • Journal of Microbiology
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    • v.40 no.1
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    • pp.1-10
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    • 2002
  • At the dose of 1000 p.f.u. per mouse,100% mortality occurred in mice inoculated with wild-type pseudorabies virus (PrV). In contrast, upon stable deletion of 10 bp nucleotides at the Bsrl site within the TK gene, PrV was rendered to be completely apathogenic. The deletion also caused the virus to be less capable of replicating in respiratory as well as in nervous system tissues. Although animals were exposed to high titers of TK-deleted PrVs, the virus failed to replicate to a high titer as compared to the pathogenic parental virus. In contrast to previous studies the deletion in the TK gene did not prevent the virus from establishing latency. Upon immunosuppression, the latent virus? however, reactivated but replicated at low titers. Interestingly, TK-deleted virus established latency and reactivation, that are occurred only in trigeminal ganglia and the cerebrums and no other tissues involved. Following reactivation, there was no indication of virus shedding in respiratory tissues as confirmed by virus isolation and polymerase chain reaction (PCR) technique targeting at the gB gene of PrV, The non-pathogenic virus with non-shedding characteristics, upon reactivation of the latent virus, would be the important feature of a live virus vaccine candidate.

유전자 알고리즘을 활용한 데이터 불균형 해소 기법의 조합적 활용

  • Jang, Yeong-Sik;Kim, Jong-U;Heo, Jun
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • 2007.05a
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    • pp.309-320
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    • 2007
  • The data imbalance problem which can be uncounted in data mining classification problems typically means that there are more or less instances in a class than those in other classes. It causes low prediction accuracy of the minority class because classifiers tend to assign instances to major classes and ignore the minor class to reduce overall misclassification rate. In order to solve the data imbalance problem, there has been proposed a number of techniques based on resampling with replacement, adjusting decision thresholds, and adjusting the cost of the different classes. In this paper, we study the feasibility of the combination usage of the techniques previously proposed to deal with the data imbalance problem, and suggest a combination method using genetic algorithm to find the optimal combination ratio of the techniques. To improve the prediction accuracy of a minority class, we determine the combination ratio based on the F-value of the minority class as the fitness function of genetic algorithm. To compare the performance with those of single techniques and the matrix-style combination of random percentage, we performed experiments using four public datasets which has been generally used to compare the performance of methods for the data imbalance problem. From the results of experiments, we can find the usefulness of the proposed method.

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The Study on the Composition of the Encoder for Driving the High Speed Spindle Motor (고속 스핀들 전동기 구동을 위한 자기식 엔코더 구성에 관한 연구)

  • Choi Cheol;Kim Cheol-U;Lee Sang-Hun
    • The Transactions of the Korean Institute of Electrical Engineers B
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    • v.54 no.5
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    • pp.253-259
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    • 2005
  • Magnetic encoder with relatively low pulse per rotation is generally used for detecting speed of the high-speed rotating machine. It is due to the fact of the mechanical problems of vibration and bearing stiffness and also the limit of maximum output pulse of the mounted encoder. The magnetic encoder is divided into two types, that is, toothed gear-wheel method and magnetic wheel method according to the shape of the rotation disk. In case of detecting speed by the tooth gear-wheel, the encoder itself can be acted as the additional inertia where the number of tooth determining the output pulse and the width of the wheel detecting the change of the magnetic flux density are relatively enough large considering the volume of the rotating machine. While the magnetic wheel method has the limit of the magnetizing number of the ring magnet, there is relatively few, if nv, the influence of inertia on the machine. In this paper, it is proposed a simple magnetic wheel encoder suited for the high speed rotating machine and the method of signal processing and the output characteristics are examined through the V/F operation of max 48,000(rpm) and 2.4(KW) spindle motor.

Study metal-grade silicon manufacturing and slag refining for the production of silicon solar cell (태양전지용 실리콘 생산을 위한 금속급 실리콘 제조와 슬래그 정련 연구)

  • Lee, Sangwook;Kim, Daesuk;Park, Dongho;Moon, Byung Moon;Min, Dong Jun;Yu, Tae U
    • 한국신재생에너지학회:학술대회논문집
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    • 2011.05a
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    • pp.111.2-111.2
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    • 2011
  • 야금학적 방법을 통한 태양전지용 실리콘 제조를 위하여 아크로(Arc furnace)에서 제조된 용융 상태의 금속급 실리콘을 슬래그와 직접 반응시켜 불순물을 제거하는 공정에 관한 연구를 수행하였다. 이를 위해 아크로와 고주파 유도용해로(High-frequency induction furnace)를 이용하여 금속급 실리콘을 제조와 정련 특성 실험을 수행하였다. 본 연구에서 금속급 실리콘을 제조하기 위한 장비로 150kW급-DC 아크로와 300kW급-AC 아크로를 사용하였다. 원재료로 규석, 코크스(Cokes), 숯, 그리고 우드칩(Wood chip)을 실험 비율에 맞춰 아크로 내부에 장입하고, 이를 용융환원 방법을 통해 반응을 시켰다. 이때 생산된 금속급 실리콘의 순도는 약 99.2~99.8% 이었으며, 원재료의 순도, 장입 비율 및 아크로 운전 특성에 따라 편차가 있다. 아크로에서 생산된 금속급 실리콘의 경우 인(phosphorus), 붕소(boron)를 다량 함유하고 있고, 이를 제거하기 위하여 50kW급 고주파 유도용해로 장비를 사용하여 슬래그 정련 실험을 수행하였다. 슬래그 정련시 사용한 성분은 SiO2, CaO 그리고 CaF2 이며, 금속급 실리콘과 슬래그의 질량비 및 반응 시간에 따른 실리콘 불순물 특성을 평가하였다. 실험결과 인과 붕소는 각각 1 ppm 이하, 5 ppm 이하 였으며, 칼슘을 제외한 대부분의 금속 불순물의 경우 0.1~0.2% 임을 확인하였다.

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Isoconversional Cure Kinetics of Modified Urea-Formaldehyde Resins with Additives

  • Park, Byung-Dae
    • Current Research on Agriculture and Life Sciences
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    • v.30 no.1
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    • pp.41-50
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    • 2012
  • As a part of abating formaldehyde emission of urea-formaldehyde resin, this study was conducted to investigate the rmalcure kinetics of both neat and modified urea-formaldehyde resins using differential scanning calorimetry. Neat urea-formaldehyde resins with three different formaldehyde/urea mol ratios (1.4, 1.2 and 1.0) were modified by adding three different additives (sodium bisulfite, sodium hydrosulfite and acrylamide) at two different levels (1 and 3wt%). An isoconversional method at four different heating rates was employed to characterize thermal cure kinetics of these urea-formaldehyde resins to obtain activation energy ($E{\alpha}$) dependent on the degree of conversion (${\alpha}$). The $E{\alpha}$ values of neat urea-formaldehyde resins (formaldehyde/urea = 1.4 and 1.2) consistently changed as the ${\alpha}$ increased. Neat and modified urea-formaldehyde resins of these two F/U mol ratios did show a decrease of the $E{\alpha}$ at the final stage of the conversion while the $E{\alpha}$ of neat urea-formaldehyde resin (formaldehyde/urea = 1.0) increased as the ${\alpha}$ increased, indicating the presence of incomplete cure. However, the change of the $E{\alpha}$ values of all urea-formaldehyde resins was consistent to that of the Ea values. The isoconversional method indicated that thermal cure kinetics of neat and modified urea-formaldehyde resins showed a strong dependence on the resin viscosity as well as diffusion control reaction at the final stage of the conversion.

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A Study of Improvement on the Quickness of Current controller for Permanent Magnet Synchronous Motor (PMSM 전류제어기의 속응성 향상에 관한 연구)

  • Cho, Su-Eog;Lee, Jeong-Hwan;Kim, Cheul-U
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.21 no.8
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    • pp.136-143
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    • 2007
  • A improved current controller with reference modification part that has both fast transient response in transient state and high accuracy in steady state is proposed. In this scheme, a improved reference modification part is used to synchronous frame PI controller for the fast transient state. The transient response of current controller is seriously deteriorated in high back e.m.f.(electromotive force) due to the lack of DC link control voltage. This paper is proposed that the improved reference modification part is compared with voltage limit and reference voltage.

Hydrogen Detecting Characteristics of the $WO_3$ Films Using the R/V Converting Circuit (저항-전압변환회로를 이용한 $WO_3$ 박막의 수소검지 특성 측정)

  • Rhie, Dong-Hee;Koh, Jung-Hyuk;Kim, Young-Hwan;Sung, Yung-Kwon
    • Proceedings of the KIEE Conference
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    • 1998.11c
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    • pp.767-769
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    • 1998
  • Using the R/V converting circuit, hydrogen detecting characteristics of the $WO_3$ films were investigated. The R/V converting circuit is configured with the equivalently constant current driving method connecting an unknown resistor to be measured in the feedback loop of the or-amr rather than using a separated constant current circuit. The response time of the reference voltage for the R/V converting circuit was simulated by the circuit simulator "SABER", and it was found that the response time in the high resistance range become longer and the error amounts to 10%. From the simulation results. replacing the capacitor in the feedback loop of the second stage or-amp with a 0.001uF capacitor, when measuring in the high resistance range, the response characteristics are remarkably improved. The response time was shortened from about 10 seconds to below 1 second. Using this circuit, the effect of $WO_3$ films deposited by sputtering method on hydrogen was measured.

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Phylogenetic position of Carex splendentissima, a Korean endemic sedge (Cyperaceae)

  • CHUNG, Kyong-Sook;YANG, Sungyu;NAM, Bo-Mi
    • Korean Journal of Plant Taxonomy
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    • v.50 no.3
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    • pp.253-261
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    • 2020
  • Carex splendentissima U. Kang & J. M. Chung, endemic to the Korean peninsula, is characterized by staminate terminal spikes and glabrous elliptic perigynia. Based on its broad leaves, androgynous spikes, and tri-stigmatic features, the species has been placed in Carex sect. Siderostictae Franch. ex Ohwi, an East Asian section and a basal group in the genus. To clarify the monophyly and phylogenetic position of the species, a molecular study using the internal transcribed spacer region of nuclear ribosomal DNA and chloroplast DNA (trnL-F) data was conducted. The DNA sequence data of ten taxa in sect. Siderostictae and closely related taxa (two taxa in sect. Surculosae) with outgroups were analyzed based on maximum parsimony and maximum likelihood (ML) criteria. In the analyses, C. splendentissima was monophyletic and placed within the Siderostictae clade (sect. Siderostictae + two species of sect. Surculosae), forming a clade with C. ciliatomarginata and C. pachygyna (endemic to Japan). The clade (C. splendentissima + C. ciliatomarginata + C. pachygyna) shows evidence of diploidy. Furthermore, C. splendentissima is a sister to C. ciliatomarginata in the ML tree, and the two taxa have staminate terminal spikes. This study also updates the distribution of C. splendentissima and provides keys to the four Korean taxa in sect. Siderostictae. To conserve the endemic species C. splendentissima, further research on its genetic and ecological features should be conducted at the population level.

An Analysis on Thermal Performance and Economic of Heat Recovery Ventilation System Integrated with Window (창호통합형 배열회수 환기시스템의 열성능 및 경제성 평가)

  • Sung, Uk-Joo;Cho, Soo;Song, Kyoo-Dong
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.24 no.8
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    • pp.646-655
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    • 2012
  • This study is intended to analyze the thermal performance and evaluate the applicability about non-duct type heat recovery ventilation system integrated with window. Eventually, economic analysis of the system is conducted according to building energy saving ratio of it. As results of the thermal performance, the U-factor of the window conducted on the basis of KS F 2278 appears to $1.8W/m^2K$, and the effective heat exchange efficiency of the ventilator conducted on the basis of KS B 6879 appears 49.95% for cooling, 66.89% for heating. In the applicability evaluated by TRNSYS 16, the caes of applying the heat recovery ventilator integrated with window is found to reduce the cooling or heating load by 2.9% or 13.5% than the non-ventilator case. The results of economic analysis taking a side of consumer is verified as the payback is 3 years, and the accumulated earning is 1,408,133 won in terms of '600,000 won/unit' for initial cost, 10 years for useful life of the system.

Optical packaging technology and characterization of analog PIN-Photodiode (Analog용 PIN-Photodiode의 광 패키징 기술 및 특성 연구)

  • Lee Chang Min;Kwon Kee Young
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.42 no.3 s.333
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    • pp.17-24
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    • 2005
  • We fabricated PIN-Photodiodes with a single mode fiber for analog communications and analyzed characteristics of the devices. The fabricated PIN-Photodiode shows a bandwidth of 1.5 GHz, a dark current of 20 p4 a capacitance of 0.48 pF, and the responsivity of 0.9 V/W, a second order distortion of -72 dBc. In this paper, we developed a new optical Packaging technology that is aligning in real-time monitoring of both responsivity and IM2 characteristics. As a result responsivity has been improved by 0.03 V/W, and also U has been improved by $3\~5\;dBc$. On the other hand, failure ratio has been reduced by $3.5\%$.