• Title/Summary/Keyword: Type Synthesis

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A Study on Component Modular Approach for Type Synthesis Automation of Mechanism (기구 형태설계 자동화를 위한 컴포넌트 모듈 접근법에 관한 연구)

  • 김봉주;윤호업;신중호;권순만;장세원
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2004.10a
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    • pp.1270-1273
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    • 2004
  • The mechanism design is synthesis of suitable mechanism which can be output motions about input motions. That has generally two steps which are the type synthesis and the dimensional synthesis. And required mechanism analysis step for confirming middle or final result. The type synthesis is definition of mechanism type which required aim and the dimensional synthesis is calculation of dimension about defined type mechanism. The type synthesis of mechanism is included qualitative design field which isn't defined systematic design method. especially, the most difficult step for mechanism design automation. In this paper proposed the component modular design method which is figured mechanism types automate with component modules using component modular approach. And develop CAD(Computer Aided Program) program for application.

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Conceptual Design of New Six-Bar Robot Hand by Type Synthesis (형태합성에 의한 새로운 6 절 기구 로보트 손의 개념설계)

  • 이경원;이황진
    • Journal of the Korean Society for Precision Engineering
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    • v.17 no.6
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    • pp.63-68
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    • 2000
  • This paper describes the conceptual design of new robot hand by type synthesis. The conventional robot hands with rotational movement have bad controllability because the distance between the final rotational joint and the center of things grasped is changed according to the size of things grasped. This paper uses the systematic procedure of type synthesis and the knowledge for designing robot hands. The new 6-bar Watt I type conceptual robot hand with rectilinear translational movement is proposed.

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Human collagen alpha-2 type I stimulates collagen synthesis, wound healing, and elastin production in normal human dermal fibroblasts (HDFs)

  • Hwang, Su Jin;Ha, Geun-Hyoung;Seo, Woo-Young;Kim, Chung Kwon;Kim, KyeongJin;Lee, Sang Bae
    • BMB Reports
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    • v.53 no.10
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    • pp.539-544
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    • 2020
  • Skin aging appears to be the result of overlapping intrinsic (including genetic and hormonal factors) and extrinsic (external environment including chronic light exposure, chemicals, and toxins) processes. These factors cause decreases in the synthesis of collagen type I and elastin in fibroblasts and increases in the melanin in melanocytes. Collagen Type I is the most abundant type of collagen and is a major structural protein in human body tissues. In previous studies, many products containing collagen derived from land and marine animals as well as other sources have been used for a wide range of purposes in cosmetics and food. However, to our knowledge, the effects of human collagen-derived peptides on improvements in skin condition have not been investigated. Here we isolate and identify the domain of a human COL1A2-derived protein which promotes fibroblast cell proliferation and collagen type I synthesis. This human COL 1A2-derived peptide enhances wound healing and elastin production. Finally, the human collagen alpha-2 type I-derived peptide (SMM) ameliorates collagen type I synthesis, cell proliferation, cell migration, and elastin synthesis, supporting a significant anti-wrinkle effect. Collectively, these results demonstrate that human collagen alpha-2 type I-derived peptides is practically accessible in both cosmetics and food, with the goal of improving skin condition.

Novel Synthesis of 3-Phenyl-chromen-4-ones Using N-Heterocyclic Carbene as Organocatalyst: An Efficient Domino Catalysis Type Approach

  • Mishra, Priya;Singh, Sarita;Ankit, Preyas;Fatma, Shahin;Singh, Divya;Singh, Jagdamba
    • Bulletin of the Korean Chemical Society
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    • v.34 no.4
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    • pp.1070-1076
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    • 2013
  • Herein is reported a simple and efficient synthesis of isoflavones starting from various substituted phenacyl bromides and salicylaldehydes in presence of NHC. The mechanism involved domino catalysis type approach with consumption and regeneration of catalyst in two catalytic cycles. This method proved to be very lucrative and gives very good yield. The method described here represents an environmentally benign alternative to classical approach.

Effects of human collagen α-1 type I-derived proteins on collagen synthesis and elastin production in human dermal fibroblasts

  • Hwang, Su Jin;Kim, Su Hwan;Seo, Woo-Young;Jeong, Yelin;Shin, Min Cheol;Ryu, Dongryeol;Lee, Sang Bae;Choi, Young Jin;Kim, KyeongJin
    • BMB Reports
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    • v.54 no.6
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    • pp.329-334
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    • 2021
  • Collagen type I is the most abundant form of collagen in human tissues, and is composed of two identical α-1 type I chains and an α-2 type I chain organized in a triple helical structure. A previous study has shown that human collagen α-2 type I (hCOL1A2) promotes collagen synthesis, wound healing, and elastin production in normal human dermal fibroblasts (HDFs). However, the biological effects of human collagen α-1 type I (hCOL1A1) on various skin properties have not been investigated. Here, we isolate and identify the hCOL1A1-collagen effective domain (CED) which promotes collagen type I synthesis. Recombinant hCOL1A1-CED effectively induces cell proliferation and collagen biosynthesis in HDFs, as well as increased cell migration and elastin production. Based on these results, hCOL1A1-CED may be explored further for its potential use as a preventative agent against skin aging.

Modeling, Preparation, and Elemental Doping of Li7La3Zr2O12 Garnet-Type Solid Electrolytes: A Review

  • Cao, Shiyu;Song, Shangbin;Xiang, Xing;Hu, Qing;Zhang, Chi;Xia, Ziwen;Xu, Yinghui;Zha, Wenping;Li, Junyang;Gonzale, Paulina Mercedes;Han, Young-Hwan;Chen, Fei
    • Journal of the Korean Ceramic Society
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    • v.56 no.2
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    • pp.111-129
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    • 2019
  • Recently, all-solid-state batteries (ASSBs) have attracted increasing interest owing to their higher energy density and safety. As the core material of ASSBs, the characteristics of the solid electrolyte largely determine the performance of the battery. Thus far, a variety of inorganic solid electrolytes have been studied, including the NASICON-type, LISICON-type, perovskite-type, garnet-type, glassy solid electrolyte, and so on. The garnet Li7La3Zr2O12 (LLZO) solid electrolyte is one of the most promising candidates because of its excellent comprehensively electrochemical performance. Both, experiments and theoretical calculations, show that cubic LLZO has high room-temperature ionic conductivity and good chemical stability while contacting with the lithium anode and most of the cathode materials. In this paper, the crystal structure, Li-ion transport mechanism, preparation method, and element doping of LLZO are introduced in detail based on the research progress in recent years. Then, the development prospects and challenges of LLZO as applied to ASSBs are discussed.

Operation Characteristics of Gasification/Melting Pilot Plants for Synthesis Gas Production using Coal and Waste (석탄 및 폐기물로부터 합성가스 제조를 위한 가스화용융 Pilot Plant 운전특성)

  • Chung, Seok-Woo;Yun, Yong-Seung;Yoo, Young-Don
    • 한국신재생에너지학회:학술대회논문집
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    • 2005.06a
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    • pp.561-564
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    • 2005
  • Gasification has been regarded as a very important technology to decrease environmental pollution and to obtain higher efficiency. The gasification process converts carbon containing feedstock into a synthesis gas, composed primarily of CO and $H_2$. And the synthesis gas can be used as a source for power generation or chemical material production. Through more than nine years, IAE developed and upgraded several gasification/melting pilot plant system, and obtained a good quality synthesis gas. This paper illustrates the gasification characteristics and operation results of two 3 ton/day synthesis gas production facilities. One is entrained-bed slagging type coal gasifier system which is normally operated in the temperature range of $1,400\~1,450^{\circ}C,\;8\~10$ bar pressure. And the other is fixed-bed type gasification/melting furnace system using MSW and industrial wastes as a feedstock.

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Sentence Type Identification in Korean Applications to Korean-Sign Language Translation and Korean Speech Synthesis (한국어 문장 유형의 자동 분류 한국어-수화 변환 및 한국어 음성 합성에의 응용)

  • Chung, Jin-Woo;Lee, Ho-Joon;Park, Jong-C.
    • Journal of the HCI Society of Korea
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    • v.5 no.1
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    • pp.25-35
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    • 2010
  • This paper proposes a method of automatically identifying sentence types in Korean and improving naturalness in sign language generation and speech synthesis using the identified sentence type information. In Korean, sentences are usually categorized into five types: declarative, imperative, propositive, interrogative, and exclamatory. However, it is also known that these types are quite ambiguous to identify in dialogues. In this paper, we present additional morphological and syntactic clues for the sentence type and propose a rule-based procedure for identifying the sentence type using these clues. The experimental results show that our method gives a reasonable performance. We also describe how the sentence type is used to generate non-manual signals in Korean-Korean sign language translation and appropriate intonation in Korean speech synthesis. Since the method of using sentence type information in speech synthesis and sign language generation is not much studied previously, it is anticipated that our method will contribute to research on generating more natural speech and sign language expressions.

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