• Title/Summary/Keyword: Type II

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Effect of Periodic Walking on the Type II Muscle of Growing Suspended Rats (주기적인 보행이 성장하는 어린뒷다리부유쥐의 Type II 근육에 미치는 효과)

  • 최명애
    • Journal of Korean Academy of Nursing
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    • v.26 no.2
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    • pp.271-280
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    • 1996
  • The purpose of this study was to determine the effect of periodic walking during hindlimb suspension on the mass, relative weight, fiber type distribution and cross-sectional area of Type I and II fibers in the developing Type II plantaris muscle. To examine the effectiveness of periodic walking on mass and fiber size, the hindlimbs of young female Wistar rats were suspended (HS group) and half of these rats walked on a treadmill for 45 min/day(15 min every 4 hours) at 5 meters/min at a 15 degree grade(HS-W group) After seven days of hindlimb suspension, the plantaris muscle wet weight was 28.40% significantly smaller(P<0.005) and relative plantaris muscle weight was 26.97% smaller compared with those of control rats(P<0.05). The plantaris muscle wet weight and the relative plantaris muscle weight increased by 46.60% and 49.23% respectively with periodic walking, moreover. the plantaris muscle wet weight and the relative plantaris muscle weight of the HS-W rats recovered to the level of the control rats. No change was observed in fiber type percentage of the developing plantaris muscle following one week of hindlimb suspension or periodic walking during hindlimb suspension. Type I and II fiber cross-sectional areas of the developing plantaris muscle were 42.51% and 43. 68% lower in the HS group than in the control group(p<0.0001), Type I and II fiber cross-sectional areas of the developing plantaris were 30.82% and 45.97% greater in the HS-W group than in the HS group(p<0.0001), whereas Type I and II fiber cross-sectional area of HS-W group were less than those of the control group(P<0.0001) The results suggest that periodic walking can attenuate developing plantaris muscle atrophy induced by hindlimb suspension.

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Establishment of Criteria for the Evaluation of Headgear and Ornaments for Diadem in the Period of the Three States (삼국시대 관모 및 관식 유물 감정을 위한 기준 설정)

  • Kim, Moon-Ja
    • Journal of the Korean Society of Costume
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    • v.58 no.5
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    • pp.13-34
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    • 2008
  • In Headgear and Ornaments for Diadem in the Period of the Three States there was Conical Cap(or Pointed Cap), Feathered Cap(Trim), and Crown[Tree-typed Diadem and Tree and Antler-typed Diadem] was excavated from the tombs. Feathered Trim is 5 types, Feathered Trim I-A, Feathered Trim I-B, Feathered Trim II-A, Feathered Trim II-B, Feathered Trim II-C in according to upper part of central insert plate style. Feathered Trim I-A, I-B, II-B type was general style that was found in most of the old tombs in ancient Silla, Gaya. Feathered Trim II-A type was excavated from the only Silla tombs and II-C type was excavated from Gaya tombs. The Ornaments for Diadem in Baekje was excavated from the tombs is adorned with a arranged leaf-stems on either sides and the flower-shaped. They were distinguished with the original mode of Goguryeo and ancient Silla at the time. Tree-typed Diadem is five part in according to the Mountain(;山)-typed piled up. Only one Mountain(;山)-typed one in three stand-up ornament(I-1 type), and three step one in three stand-up one(I-2 type), modification one (I-3 type), three step one of four and five stand-up ones(I-4 type), and four step one of four and five stand-up ones (I-5 type). Tree and Antler-typed Diadem is three part in according to the step of Mountain(; 山)-typed and cross-shaped of the upper part. Three one of three step one of Mountain(;山)-typed and two Antler- typed (II-1 type), cross-shaped one(II-2 type), four step one(II-3 type).

Strength Properties of Wooden Model Retaining Wall Using Preservative Treated Square Timber of Domestic Pinus rigida Miller (리기다소나무 방부 정각재를 이용한 목재 옹벽의 강도 성능 평가)

  • Park, Jun-Chul;Kim, Keon-Ho;Lee, Dong-Heub;Hwang, Won-Joung;Hong, Soon-Il
    • Journal of the Korean Wood Science and Technology
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    • v.38 no.6
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    • pp.532-540
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    • 2010
  • The strength properties of wooden model retaining wall made of pitch pine (Pinus rigida Miller) was evaluated. Three different types of wooden model retaining wall were made of the 11cm square timber treated with CUAZ-2 (Copper Azole). The retaining wall was made into the 4 layers of crossbar and the 3 layers of vertical-bar, of which the size was 86 cm high, 200 cm long and 96 cm wide. Type I was control and in Type II 20 cm vertical-bars and 93 cm vertical-bars were arranged alternately to decrease wood usage. TypeIII was similar to TypeII except that the connection between crossbars was reinforced with the wooden armature. In each type, the strength properties of retaining wall were investigated by horizontal loading test and the deformation of structure by image processing (AICON 3D DPA-PRO system). In horizontal loading test of Type I, Type II and Type III was 63.17, 57.80, and 60.97 kN/m, respectively. The deformation of the top layer in Type II was 1.5 times larger than in Type I and Type III. Consequently, the economic efficiency and strength performance were better in Type III than in Type I and Type II.

Angiotensin II-Induced Generation of Reactive Oxygen Species Is Regulated by a Phosphatidylinositol 3-Kinase/L-Type Calcium Channel Signaling Pathway (Angiotensin II에 의해 유도되는 활성산소발생 기전에 대한 연구)

  • Jin, Seo Yeon;Ha, Jung Min;Kim, Young Whan;Lee, Hye Sun;Bae, Sun Sik
    • Journal of Life Science
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    • v.25 no.2
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    • pp.231-236
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    • 2015
  • Angiotensin II (AngII) is an essential hormone that affects vascular physiology. For example, stimulation of vascular smooth muscle cells (VSMCs) rapidly induces vasoconstriction and results in the up-regulation of blood pressure. Chronic stimulation of VSMCs with AngII also results in hypertrophy. In this study, we confirmed an involvement of phosphatidylinositol 3-kinase (PI3K)-dependent calcium mobilization in AngII-induced generation of reactive oxygen species (ROS). Stimulation of rat aortic smooth muscle cells (RASMCs) with AngII significantly induced the generation of ROS in a dose- and time-dependent manner. AngII-induced generation of ROS was completely abolished by pharmacological inhibition of PI3K (with LY294002), but inhibition of the ERK signaling pathway had no effect. AngII-induced calcium mobilization was completely blocked by inhibition of PI3K, whereas inhibition of the ERK signaling pathway by PD98059 was ineffective. Depletion of extracellular calcium or inhibition of the L-type calcium channel by nifedipine completely blocked AngII-induced calcium mobilization. Depletion of extracellular calcium by EGTA and incubation of RASMCs with calcium-free medium both significantly blocked AngII-induced ROS generation. Inhibition of the L-type calcium channel also significantly blocked AngII-induced ROS generation. These results suggest that AngII-induced ROS generation is regulated by calcium mobilization, which, in turn, is modulated by a PI3K/L-type calcium channel signaling pathway.

Prevalence of fimA Genotypes of Porphyromonas gingivalis Strains in peri-implantitis patients (임플란트주위염시 Porphyromonas gingivalis 섬모유전형의 출현율)

  • Shin, Seung-Il;Kwon, Young-Hyuk;Park, Joon-Bong;Herr, Yeek;Chung, Jong-Hyuk
    • Journal of Periodontal and Implant Science
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    • v.35 no.1
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    • pp.31-41
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    • 2005
  • Fimbriae (fimA) of Porphyromonas gingivalis are filamentous components on the cell surface and are thought to play an important role in the colonization and invasion of periodontal tissue. P. gnigivalis fimA gene encoding fimbrillin, a subunit of fimbriae, has been classified into 5 genotypes (types I to V) based on the nucleotide sequences. In the present study, we examined the prevalence of these fimA genotypes in patients with dental implant and the relationship between prevalence of these genotypes and peri-implantitis. Dental plaque specimens obtained from 80 peri-implant sulci of 50 patients with dental implants were analyzed by 16S rRNA fimA gene-directed PCR assay. P. gingivalis were detected in 74.4% of the samples of the control group (healthy peri- implant sulci; probing depth<5mm) and in 92.0% of the samples of the test group (peri-implant sulci with peri-iimplantitis; probing $depth{\geqq}5mm$). Among the P. gingivalis-positive samples of the control group, the most prevalent fimA type was type I (29.3%), followed by type II (26.8%). In contrast, a majority among the P. gingivalis-positive samples of the test group was type II (56.S%), followed by type I (43.5%). TypeII fimA genotype organisms were detected more frequently in the test group and a significant difference in the occurrence of type II was observed between test and the control groups. A correlation between specific fimA types and peri-implant health status was found in type II (OR 3.545) and only a weak relationship was revealed in typeIV(OR 3.807). These findings indicate that P. gingivalis strains that possess type II fimA are predominant in peri-implant sulci with peri-implantitis and are closely associated with peri-implant health status. P. gingivalis with type II fimA may be involved in peri-implantitis.

The Effects of the cis and trans Configurations of Ligands on the Calculated Dipole Moments for $[M(II)O_3N_3]$ and $[Ni(II)O_2N_4]$ Type Complexes ($[M(II)O_3N_3]$$[Ni(II)O_2N_4]$ 형태착물의 쌍극자 모멘트에 대한 리간드의 cis 및 trans 구조의 영향)

  • Sangwoon Ahn;Eu Suh Park;Chang Jin Choi
    • Journal of the Korean Chemical Society
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    • v.27 no.2
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    • pp.83-94
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    • 1983
  • The effects of cis and trans configurations of ligands for $[M(II)O_3N_3]$ and $[Ni(II) O_2N_4]$ type complexes [M(II) = Co(III), Ni(II) and Cu(II)] on the calculated dipole moments have been investigated, adpoting the eigenvectors of EHT calculation. The calculated dipole moments for cis complexes are higher than those of trans complexes. The calculated dipole moments for the octahedral trans $[Co(III)O_3N_3]$ type complex fall in the range of experimental values. However the calculated dipole moments for cis $[Ni(II) O_2N_4]$ type complexes fall in the range of the experimental values. These results predicts the trans structure for $[Co(III)O_3N_3]$ and $[Ni(II) O_2N_4]$ type complexes. Those structures are in agreement with the experimental one (Three bidentate (O-N) ligands in $[M(II)O_3N_3]$ type complexes coordinate to the metal ion and two tridentate (O-N-N) ligands in [Ni(II)O2N4] type complexes coordinate to Ni(II) ion).

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Goodness-of-fit Test for the Weibull Distribution Based on Multiply Type-II Censored Samples

  • Kang, Suk-Bok;Han, Jun-Tae
    • Communications for Statistical Applications and Methods
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    • v.16 no.2
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    • pp.349-361
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    • 2009
  • In this paper, we derive the approximate maximum likelihood estimators of the shape parameter and the scale parameter in a Weibull distribution under multiply Type-II censoring by the approximate maximum likelihood estimation method. We develop three modified empirical distribution function type tests for the Weibull distribution based on multiply Type-II censored samples. We also propose modified normalized sample Lorenz curve plot and new test statistic.

Overview of Mucolipidosis Type II and Mucolipidosis Type III α/β

  • Kim, Su Jin
    • Journal of mucopolysaccharidosis and rare diseases
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    • v.2 no.1
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    • pp.1-4
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    • 2016
  • Mucolipidosis type II (MLII; MIM#252500) and type III alpha/beta (MLIIIA; MIM#252600) very rare lysosomal storage disease cause by reduced enzyme activity of GlcNAc-1-phosphotransferase. ML II is caused by a total or near total loss of GlcNAc-1-phosphotransferase activity whether enzymatic activity in patient with ML IIIA is reduced. While ML II and ML III share similar clinical features, including skeletal abnormalities, ML II is the more severe in terms of phenotype. ML III is a much milder disorder, being characterized by latter onset of clinical symptoms and slower progressive course. GlcNAc-1-phosphotransferase is encoded by two genes, GNPTAB and GNPTG, mutations in GNPTAB give rise to ML II or ML IIIA. To date, more than 100 different GNPTAB mutations have been reported, causing either ML II or ML IIIA. Despite development of new diagnostic approach and understanding of disease mechanism, there is no specific treatment available for patients with ML II and ML IIIA yet, only supportive and symptomatic treatment is indicated.

Dependence of solar proton events on their associated activities: solar and interplanetary type II radio burst, flare, and CME

  • Park, Jinhye;Youn, Saepoom;Moon, Yong-Jae
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.1
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    • pp.80.2-81
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    • 2016
  • We investigate the dependence of solar proton events (SPEs) on solar and interplanetary type II bursts associated with solar flares and/or CME-driven shocks. For this we consider NOAA solar proton events from 1997 to 2012 and their associated flare, CME, and type II radio burst data with the following subgroups: metric, decameter-hectometric (DH), and meter-to-kilometric (m-to-km) type II bursts. The primary findings of this study are as follows. First, about half (52%) of the m-to-km type II bursts are associated with SPEs and its occurrence rate is higher than those of DH type II bursts (45%) and metric type II bursts (19%). Second, the SPE occurrence rate strongly depends on flare strength and source longitude, especially for X-class flare associated ones; it is the highest in the central region for metric (46%), DH (54%), and m-to-km (75%) subgroups. Third, the SPE occurrence rate is also dependent on CME linear speed and angular width. The highest rates are found in the m-to-km subgroup associated with CME speed 1500 kms-1: partial halo CME (67%) and halo CME (55%). Fourth, in the relationships between SPE peak fluxes and solar eruption parameters (CME linear speed, flare flux, and longitude), SPE peak flux is mostly dependent on SPE peak flux for all three type II bursts (metric, DH, m-to-km). It is noted that the dependence of SPE peak flux on flare peak flux decreases from metric to m-to-km type II burst.

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Comparison of Aerobic and Anaerobic Capacity between Sasang Consititutions and ACE Gene Polymorphismn (사상체질과 ACE 유전자 다형성 분류에 따른 유·무산소성 능력비교)

  • Seck, Dong-Sun;Park, Kyu-Jung
    • Journal of Korean Clinical Health Science
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    • v.3 no.2
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    • pp.340-353
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    • 2015
  • Purpose. This study of purpose was to to compare of Aerobic and Anaerobic Capacity between Sasang Constitutions and ACE Gene Polymorphism. Methods. 24 healthy males were participated in this experiment who were in their twenties and had no disease, then they were divided by ACE type and by Sasang constitutions with QSCC II. According to these group, the body compositon, Aerobic capacity including VO2max, Anaerobic Capacity were measured. Results. In this study, According to ACE type, ID type were 8, II were 8 and DD type were 8 persons. According to ACE type, there were significant difference among type, especially, II, ID type more than DD. II type is more higher than any type and DD type is lower in the ratio of Blood Lactic recovery. DD type was more excellent than other type in Anaerobic power. According to Sasang Constitutions, there were 8 SoYang, 5 Taeum, 11 Soeum and then no TaeYang constitution. In Aerobic capacity, Taeum constitution had significantly high means and Anaerobic threshold. In the ratio of Blood lactic recovery, Taeum constitution was excellent and SoYang had poor recovery capacity. SoYang had more excellent than other constitution significantly in Anaerobic capacity. Comparing ACE type with Sasang constitution, Soyang constitution included 4 ID types, Taeum inclued 2 II types and 2 ID types then Soeum included 6 DD types. Compared of Aerobic and Anaerobic capacity between Sasang constitutions and ACE type, Soyang constitutions were similar to ID type, Taeum similar to II type and ID type and then Soeum were DD type. Conclusions. This study had made it clear that there were similar feature between ACE type and Sasang constitutions. Also it's possible to predict the Aerobic capacity that may be foreseen by ACE type with Sasang questionnaire method but not Anaerobic capacity.