The Ministry of Health and Welfare proposed the "undergraduate program specializing in pharmaceutical industry" in 2013, as part of its roadmap to assist domestic pharmaceutical companies to become the top-tier pharma companies in near future and provide skilled personnel tailored for pharmaceutical industry. However, it is not clear whether this "undergraduate program" meets the needs of pharmaceutical industry, especially when the number of pharmacy students increased from 1,200 to 1,700 per year since 2009. The purpose of this paper is to identify which educational background is preferred by pharmaceutical companies, by surveying the CEOs of domestic pharmaceutical companies and referring to recruitment advertisements shown in medical newspapers, specified by the fields within the companies. Two independent reviewers referred to recruitment session in Yakup newspaper and Dailypharm from May 2012 until January 2014, focusing on recruitments from pharmaceutical companies targeting bachelors' degree holders with no prior experience. 749 recruitments were observed during the study period, more than 90% of which were provided by domestic pharmaceutical companies, and regardless of the companies being domestic or multinational, pharmaceutical companies' preference for pharmacists was remarkable (44.3% for domestic and 65.8% for multinational), and the preference was especially high in the fields such as Medical, R&D, Market Access (regulatory affair/pricing and reimbursement), Business Development, and Marketing. Survey results showed that the need of establishing the undergraduate program specializing in pharmaceutical industry is mixed, suggesting that although there is need for the educating personnel targeting pharmaceutical industry, the undergraduate program would not be an answer due to current PEET system. Our study concludes that in the example of pharmaceutical companies' recruitments shown in medical newspapers, pharmaceutical companies prefer pharmacy major in almost all fields of the pharmaceutical companies, yet the pharmaceutical companies still perceive the gap between current bachelor's degree holders(including pharmacy majors) and the ideal personnel required for advancing to the "top-class" pharmaceutical companies.
Journal of the Institute of Electronics and Information Engineers
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v.51
no.12
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pp.20-29
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2014
Recently, LTE is preparing to make a new leap forward LTE-A all over the world. As LTE privides high speed service, the role of mobile phones seems to change from voice to data service. According to Cisco, global mobile data traffic will increase nearly 11-fold between 2013 and 2018. Mobile video traffic will reach 75% by 2018 from 66% in 2013 in Korea. However, voice service is still the most important role of mobile phones. Thus, controllability of throughput and low BLER is indispensable for high-quality VoIP service among various type of traffic. Although the maximum AMR-WB, 23.85 Kbps is sufficient to a VoIP call, it is difficult for the LTE which can provide tens to hundreds of MB/s may not keep the certain level VoIP QoS especially in the cell-edge area. This paper proposes a new scheduling algorithm in order to improve VoIP performance after analyzing various scheduling algorithms. The proposal is the technology which applies more priority processing for VoIP than other applications in cell-edge area based on two-tier scheduling algorithm. The simulation result shows the improvement of VoIP performance in the view point of throughput and BLER.
Purpose: To identify baseline prognostic factors for survival in patients with disease progression, during or after chemotherapy for the treatment of advanced gastric or gastroesophageal junction (GEJ) cancer. Materials and Methods: We pooled data from patients randomized between 2009 and 2012 in 2 phase III, global double-blind studies of ramucirumab for the treatment of advanced gastric or GEJ adenocarcinoma following disease progression on first-line platinum- and/or fluoropyrimidine-containing therapy (REGARD and RAINBOW). Forty-one key baseline clinical and laboratory factors common in both studies were examined. Model building started with covariate screening using univariate Cox models (significance level=0.05). A stepwise multivariable Cox model identified the final prognostic factors (entry+exit significance level=0.01). Cox models were stratified by treatment and geographic region. The process was repeated to identify baseline prognostic quality of life (QoL) parameters. Results: Of 1,020 randomized patients, 953 (93%) patients without any missing covariates were included in the analysis. We identified 12 independent prognostic factors of poor survival: 1) peritoneal metastases; 2) Eastern Cooperative Oncology Group (ECOG) performance score 1; 3) the presence of a primary tumor; 4) time to progression since prior therapy <6 months; 5) poor/unknown tumor differentiation; abnormally low blood levels of 6) albumin, 7) sodium, and/or 8) lymphocytes; and abnormally high blood levels of 9) neutrophils, 10) aspartate aminotransferase (AST), 11) alkaline phosphatase (ALP), and/or 12) lactate dehydrogenase (LDH). Factors were used to devise a 4-tier prognostic index (median overall survival [OS] by risk [months]: high=3.4, moderate=6.4, medium=9.9, and low=14.5; Harrell's C-index=0.66; 95% confidence interval [CI], 0.64-0.68). Addition of QoL to the model identified patient-reported appetite loss as an independent prognostic factor. Conclusions: The identified prognostic factors and the reported prognostic index may help clinical decision-making, patient stratification, and planning of future clinical studies.
This study develops a GIS-based system which examines the adequacy of the Groundwater development project before the actual designing of the project. A system environment is constructed in order to efficiently and scientifically manage and analyze data related to Groundwater through a Server/Client environment. For this programs such as GIS S/W ArcVies3.2, RDBMS ORACLE, ArcSDE (Spatial Database Engine) are used. WHPA and AQTESOLV are employed as a underground water simulation program and Scripts, a language for ArcView, is used to develop graphic user interface (GUI). Using the system developed here, we can transfer simulation results obtained by WHPA regarding Groundwater levels in new development projects into GIS. We can also judge whether a Groundwater development project should be permitted through examining overlaps of th effects of the development and comparing with o pollutants. At the same time, the system has a feature of supporting Groundwater development and based designing through judging the proper amount of Groundwater in a new project. It is also possible to easily and quickly prepare charts and reports using the outputs of the system. Since a two-tiered system which shares DB using inter-and intranets is developed, all the departments in the ministry of agriculture and forest and the agriculture base corporation can share accurate, reliable and latest information related to Groundwater.
This research was designed to find out what is a distictive feature of the design elements of Korean women's costume and its influence by analizing the trend of Korean women's constume during the period of 1890 and 1995. The research was analized by a total of 854 random samples of clothing styles collected from materials in the museums and from articles of three leading newspapers and one of the best women's magazines in Korea. The changing trend of Korean women's costume was found out to be as follows: 1. In around 1910s, the trend of Korean women's costume has been changed into two-tier structure of both Korean and Western styles, and the typical and traditional Korean women's street wears such as 'Chang-ot' and 'Tsdechima' have been gradually diminished. 2. From 1920s, length of the Korean skirt, which was unnecessarily long and inconvenient, has been getting shorter for the convenience of walking. In addition, Korean women's underwear has become simplified, and sports wear could be seen for the first time in Korea. 3. During 1960s, the Western clothing styles have been increased rather than Korean styles as the street wear of the Korean women. 4. In 1970s, blue jeans, mini-skirts and casual wears have become a trend or fashion for women in Korea. 5. In 1980s, a fashion of unisex mode has arrived in this country, and from the year of 1987, wearing of panties among the Korean women has been increased rather than skirts wearing for the street wear. 6. During 1990s, various forma of complex styles came into being in such styles as so-called 'orange class style,' 'protruding navel T-shirts' and 'runner wear speedy.' From mid-1990s, Korean women have turned out to prefer the cute and light costumes by placing emphasis on the image of intellectual, professional and functional wears. The changing special feature of the Korean women's clothing designs could be distinctively observed during 1960s as the modernization policies in Korea have been processed during the period. The clothing trend before 1960 was to change and to solve problems of inconvenient and impractical wears, but the trend after 1960 was seen as a change to confirm a trend of the world fashion. From mid-1990s, however, preference of Korean women's self-conceited conception socially and an unquestionable changing pattern of Korean women's life.
Objectives: To protect individuals working at the site as well as the surrounding general population from a chemical accident, several emergency exposure guidance levels have been used to set a level of concern for certain chemicals. However, a level of concern has not been established for many substances that are frequently used or produced in large quantities in Korean workplaces. In the present study, we investigated the guidance levels for protecting populations from chemical exposure and the estimation of level of concern using acute inhalation and oral toxicity data. Methods: The number of chemicals to which emergency exposure guidance levels (e.g., ERPG-2, AEGL-2, PAC-2, and IDLH) can be applied were determined among 822 hazardous chemicals according to the 'Technical Guidelines for the Selection of Accident Scenarios (revised December 2016)'. The ERPG and AEGL values were compared across all three tiers for the 31 substances that appeared on both lists. We examined the degree of difference between the emergency exposure guidance levels and the estimates of level of concern calculated from acute inhalation or acute oral toxicity data. Results: Among the 822 hazardous chemicals, emergency exposure guidance levels can be applied to 359 substances, suggesting that the estimates of level of concern should be calculated using acute toxicity data for 56.3% of the hazardous chemicals. When comparing the concordance rates of ERPG and AEGL for 31 substances, the difference between the two criteria was generally small. However, about 40% of the substances have values diverging by more than three-fold in at least one tier. Such discrepancies may cause interpretation and communication problems in risk management. The emergency exposure guidance levels were similar to the estimates of level of concern calculated using acute inhalation toxicity data, but the differences were significant when using acute oral toxicity data. These results indicate that the level of concern derived from acute oral toxicity data may be insufficient to protect the population in some cases. Conclusion: Our study suggests that the development of standardized guidance values for emergency chemical exposure in the Korean population should be encouraged. It is also necessary to analyze acute toxicity data and fill the information gaps for substances that are important in Korean workplace situations.
Journal of the Korea Academia-Industrial cooperation Society
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v.22
no.1
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pp.251-256
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2021
This study analyzed the most frequently used navigation cases in a desktop environment. As a result of the research, GNB induces users' search as the top element of the search structure and can place color, text, icon, and image elements. LNB could be classified in the form of a dropdown, flyout, dropline and mega menu. In this study, the navigation structure of Interpark and Interpark among open markets used by users was analyzed. G-Market's GNB has a two-tier structure with color, text, image, and icon elements, and Interpark has a three-tiered horizontal label. Interpark's GNB drew attention by placing a badge on the seasonal label, which is a temporary content section, unlike G-market. It can be seen that the LNBs of both shopping malls have flyout menus that protrude when you mouse over the category menu arranged in a vertical text form under the logo placed on the left. The flyout menu has a complex structure consisting of the layout of the mega menu. This study is meaningful in revealing user experience elements by analyzing the GNB and LNB of shopping malls these days where internet shopping is increasing.
Lee, Yeun sook;Ko, Ji yeong;Oh, Chan ohk;Lee, Eu ddeum
Design Convergence Study
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v.14
no.6
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pp.29-55
/
2015
This study aimed to examine and compare housing conditions and satisfaction degree of working college students in Seoul metropolitan area, depending on their stress level from economic burden and living housing type. The interview using the questionnaire was conducted. The subjects were 199 working college students aged between 19 and 35. The two-tier cluster sampling method were used, the region and representative university within the region. The comparison of satisfaction degree per type of housing of working college students has been conducted to find 3 characteristic patterns of satisfaction degree per housing condition from the stress of preparing the fund for rent, and students with high degree of stress from arranging rent showed relatively low degree of satisfaction in most items. 6 patterns have been identified in terms of housing types, and most of the students living in the Gosiwon, the poorest condition and housing type, showed the lowest degree of satisfaction, while those residing in the officetel turned out to the most satisfied. This study gives implications of housing welfare for working college students.
The three-story stone pagodas in Hyeon-ri and Hwacheon-ri,Yeongyang Gyeongsangbuk-do are stone pagodas that exhibit the typical style of Unified Silla. The two pagodas are believed to have been built in the mid- and late 9th centuries at the latest, considering the style of the three-story roof stone on top of the double-tier base. This is also confirmed by the reliefs carved at the base and the first-story of the pagoda. The Four Heavenly Kings and the Twelve Zodiacal Animal Deities were first combined in the late 8th century in the stone pagoda at the Wonwonsa Temple Site, and the Eight Classes of Divine Beings was also the most popular carved pagoda reliefs in the 9th century. However, the two Yeongyang stone pagodas are characterized by a combination of the Four Heavenly Kings (1st story), the Eight Classes (top base), and the Twelve Zodiacal Animals (lower base), and the stone used for the pagoda consists of sedimentary rocks of the sandstone family, which comprise most of the geological strata in the Yeongyang area, rather than ordinary granite. The new combinations of the three types of guardian deities and the Eight Classes changed from seated to standing poses is interpreted as an attempt to enhance the Buddhist faith and cultural status of the Yeongyang area, along with the fact that the stone pagoda was built using local natural materials. The Eight Classes of the Yeongyang stone pagoda does not follow the two types of arrangement of the pagodas with the Eight Classes, but some of the deities have been relocated to a new location. Composed of AsuraGandharva on the east side, Naga-Mahoraga on the south, Deva-Garuda on the west, and Kimnara-Yaksa on the north, this form can be classified as a unique 'third layout of the Eight Classes' in the Yeongyang area. Such changes in the shape and posture of the reliefs reflect a new perception of the pagodas. The reason why the Gandharva and Yaksa statues were carved on the east and north sides, respectively, was because they were deemed subordinate to the Four Heavenly Kings, and the fact that the Naga and the Mahoraga were carved on the south side was presumed to have influenced the geographical location of the two pagodas on the northern side of Banbyeoncheon Stream. The Hyeon-ri and Hwacheon-ri three-story stone pagodas inherited the tradition of typical Unified Silla-period pagodas, while also bearing their own new regional characteristics.
Park, Jun Hyung;Kwahk, Kee-Young;Han, Heejun;Kim, Yunjeong
Journal of Intelligence and Information Systems
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v.19
no.4
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pp.21-37
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2013
Recently, as the advent of the knowledge-based society, there are more people getting interested in the intellectual property. Especially, the ICT companies leading the high-tech industry are working hard to strive for systematic management of intellectual property. As we know, the patent information represents the intellectual capital of the company. Also now the quantitative analysis on the continuously accumulated patent information becomes possible. The analysis at various levels becomes also possible by utilizing the patent information, ranging from the patent level to the enterprise level, industrial level and country level. Through the patent information, we can identify the technology status and analyze the impact of the performance. We are also able to find out the flow of the knowledge through the network analysis. By that, we can not only identify the changes in technology, but also predict the direction of the future research. In the field using the network analysis there are two important analyses which utilize the patent citation information; citation indicator analysis utilizing the frequency of the citation and network analysis based on the citation relationships. Furthermore, this study analyzes whether there are any impacts between the size of the company and patent citation relationships. 74 S&P 500 registered companies that provide IT and communication services are selected for this study. In order to determine the relationship of patent citation between the companies, the patent citation in 2009 and 2010 is collected and sociomatrices which show the patent citation relationship between the companies are created. In addition, the companies' total assets are collected as an index of company size. The distance between companies is defined as the absolute value of the difference between the total assets. And simple differences are considered to be described as the hierarchy of the company. The QAP Correlation analysis and MR-QAP analysis is carried out by using the distance and hierarchy between companies, and also the sociomatrices that shows the patent citation in 2009 and 2010. Through the result of QAP Correlation analysis, the patent citation relationship between companies in the 2009's company's patent citation network and the 2010's company's patent citation network shows the highest correlation. In addition, positive correlation is shown in the patent citation relationships between companies and the distance between companies. This is because the patent citation relationship is increased when there is a difference of size between companies. Not only that, negative correlation is found through the analysis using the patent citation relationship between companies and the hierarchy between companies. Relatively it is indicated that there is a high evaluation about the patent of the higher tier companies influenced toward the lower tier companies. MR-QAP analysis is carried out as follow. The sociomatrix that is generated by using the year 2010 patent citation relationship is used as the dependent variable. Additionally the 2009's company's patent citation network and the distance and hierarchy networks between the companies are used as the independent variables. This study performed MR-QAP analysis to find the main factors influencing the patent citation relationship between the companies in 2010. The analysis results show that all independent variables have positively influenced the 2010's patent citation relationship between the companies. In particular, the 2009's patent citation relationship between the companies has the most significant impact on the 2010's, which means that there is consecutiveness regarding the patent citation relationships. Through the result of QAP correlation analysis and MR-QAP analysis, the patent citation relationship between companies is affected by the size of the companies. But the most significant impact is the patent citation relationships that had been done in the past. The reason why we need to maintain the patent citation relationship between companies is it might be important in the use of strategic aspect of the companies to look into relationships to share intellectual property between each other, also seen as an important auxiliary of the partner companies to cooperate with.
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