• Water Engineering Research
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• v.3 no.1
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• pp.57-62
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• 2002

This research is intended to integrate long-term operation rules and real time operation policy for conservation & flood control in a reservoir. The familiar Yield model has been modified and used to provide long-term rule curves. The model employs linear programming technique under given physical conditions, i.e., total capacity, dead storage, spillways, outlet capacity and their respective elevations to find required and desired minimum storage fur different demands. To investigate the system behavior resulting from the above-mentioned operating policy, i.e., the rule curves, the simulation model was used. Results of the simulation model show that the results of the optimization model are indeed valid. After confirmation of the above mentioned rule curves by the simulation models, gate operation procedure was merged with the long term operation rules to determine the optimum reservoir operating policy. In the gate operation procedure, operating policy in downstream flood plain, i.e., determination of damaging and non-damaging discharges in flood plain, peak floods, which could be routed by reservoir, are determined. Also outflow hydrograph and variations of water surface levels for two known hydrographs are determined. To examine efficiency of the above-mentioned models and their ability in determining the optimum operation policy, Esteghlal reservoir in Iran was analyzed as a case study. A numerical model fur the solution of two-dimensional dam break problems using fractional step method is developed on unstructured grid. The model is based on second-order Weighted Averaged Flux(WAF) scheme with HLLC approximate Riemann solver. To control the nonphysical oscillations associated with second-order accuracy, TVD scheme with SUPERBEE limiter is used. The developed model is verified by comparing the computational solutions with analytic solutions in idealized test cases. Very good agreements have been achieved in the verifications.

• Journal of the Korean Society of Safety
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• v.21 no.2 s.74
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• pp.143-149
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• 2006

This paper deals with the space-time finite element analysis of two-dimensional vibration problem with a single variable. The method of space-time finite elements enables the simpler solution than the usual finite element analysis with discretization in space only. We present a discretization technique in which finite element approximations are used in time and space simultaneously for a relatively large time period. The weighted residual process is used to formulate a finite element method for a space-time domain. A stability problem is described and some investigations for chosen type of rectangular space-time finite elements are carried out. Instability is caused by a too large time step of successive time steps in the traditional time-dependent problems. It has been shown that the numerical stability of time-stepping on the larger time steps is quite good. The unstructured space-time finite element not only overcomes the shortcomings of the stability in the traditional numerical methods, but it is also endowed with the features of an effective computational technique. Some numerical examples have been presented to illustrate the efficiency of the described method.

• Bulletin of the Korean Chemical Society
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• v.23 no.6
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• pp.837-845
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• 2002

Based on ab initio calculations at the MP2(FULL)/6-31+G**//RHF/6-31G** level, we compare the energetic and mechanistic features of a model reaction for catalytic action of Δ?-3-ketosteroid isomerase (KSL,E.C.5.3,3.1) with those of a corresponding nonenzymatic reaction in aqueous solution. The results show that the two catalytic acid residues,Tyr14 and Asp99, can lower the free energy of activation by 8.6kcal/mol, which is in good agreement with the experimentally predicted~9 kcal/mol,contribution of electrophilic catalyses to the whole enzymatic rate enhancement. The dienolate intermediate formed by proton transfer from the substrate carbon acid to the catalytic base residue (Asp38) ins predicted to be stabilized by 12.0 kcal/mol in the enzymatic reaction, making its formation thermodynamically favorable. It has been argued that enzymes catalyzing the reactions of carbon acids should resolve the thermodynamic problem of stabilizing the enolate intermediate as well as the kinetic porblem of lowering the free energy of activation for porton abstraction. We find that KSI can successfully overcome the thermodynamic difficulty ingerent in the nonenzymatic reaction through the electrophilic catalyses of the two acid residues. Owing to the stabilization of dienolate intermediate, the reketonization step could influence the overall reaction rate more significantly in the KSI- catalyzed reaction than in the nonenzymatic reaction, further supporting the previous experimental findings. However, the electrophilic catalyses alone cannot account for the whole catalygic capability (12-13 kcal/mol), confiming the earlier experimental implications for the invement of additional catalytic components. The present computational study indicates clearly how catalytic residues of KSI resolve the fundamental problems associated with the entropic penalty for forming the rate-limiting transition state and its destabilization in the bulk solvation environment.

• Restorative Dentistry and Endodontics
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• v.17 no.2
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• pp.365-382
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• 1992

The purpose of this study was to evaluate the adaptation of filling material to the dentinal walls of root canals with and without smear layer. Fifty extracted upper and lower anterior teeth were selected, and the root canals were instrumented with K - files 1mm short of the apical foramen by step - back method. The teeth were randomly divided into two groups of 25 each : in the group I, smear layers were not removed, and in the group II, smear layers were removed by 15% EDTA solution. Again the two groups 25 teeth were randomly divided into unfilled contol group and filling groups(lateral, ultrasonic, ULTRAFIL, McSpadden compaction group). Upon completion of root canal filling, the teeth were grooved on the both the labial and lingual surfaces and then split with mallet and chisel. Each specimens were examined with JSM - 840 Scanning Electron Microscope (JEOL., Japan). The results were as follows : 1. In the contol group, dentinal tubules of group I couldn't be distinguished in the canal wall, but those of group II appeared to be open and patent. 2. In the filling groups of group I, the tubular penetration of the sealer or gutta percha couldn't be seen, but in the filling groups of group II, it could be seen except McSpadden compaction group. 3. In the filling groups, ULTRAFIL group showed the best adaptation of filling material to root canal wall among the group I, and lateral and ultrasonic condensation group showed the best adaptation of filling material among the group II. McSpadden compaction group showed the worst adaptation in group I, II. 4. Generally, the group II showed better adapation of filling material to root canal wall than the group I.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.44 no.6
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• pp.16-23
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• 2007

Changeable biometrics has been developed as a solution to problem of enhancing security and privacy. The idea is to transform a biometric signal or feature into a new one for the purposes of enrollment and matching. In this paper, we propose a changeable biometric system that can be applied to appearance based face recognition system. In the first step when using feature extraction, ICA(Independent Component Analysis) coefficient vectors extracted from an input face image are replaced randomly using their mean and variation. The transformed vectors by replacement are scrambled randomly and a new transformed face coefficient vector (transformed template) is generated by combination of the two transformed vectors. When this transformed template is compromised, it is replaced with new random numbers and a new scrambling rule. Because e transformed template is generated by e addition of two vectors, e original ICA coefficients could not be easily recovered from the transformed coefficients.

• Journal of Ocean Engineering and Technology
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• v.29 no.2
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• pp.154-162
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• 2015

In this study, experimental and numerical methods were applied to observe sloshing impact phenomena. A two-dimensional rectangular tank filled with water and air was considered with a specific excitation condition that induced a hydrodynamic impact without an air pocket at the top corner of the tank. High-speed cameras and a pressure measurement system were synchronized, and a particle image velocimetry (PIV) technique was applied to measure the velocity field and corresponding pressure. The experimental condition was implemented in a numerical computation to solve incompressible two-phase flows using a Cartesian-grid method. The discretized solution was obtained using the finite difference and constraint-interpolation-profile (CIP) methods, which adopt a fractional step scheme for coupling the pressure and velocity. The tangent of the hyperbola for interface capturing (THINC) scheme was used with the weighed line interface calculation (WLIC) method to capture the interface between the air and water. The calculated impact pressures and velocity fields were compared with experimental data, and the relationship between the local velocity and pressure was investigated based on the computational results.

• Journal of the Korean Chemical Society
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• v.21 no.3
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• pp.171-179
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• 1977

Proton magnetic resonance spectra of five glycine-containing dipeptides glycyl-L-valine, L-valyl-glycine, glycyl-DL-alanine, glycyl-DL-serine and glycyl-L-aspartic acid in $D_2O$ were investigated as a function of pH at room temperature. From the analysis of the spectra, it was found that the chemical shift of the $C_{\alpha}H,\;C_{\beta}H\;and\;C_rH$protons varies with pH as a one-step titration curve, and that the spin-spin coupling constant remains almost unchanged. Two distinct values of the chemical shift for $C_{\alpha}H,\;C_{\beta}H\;or\;C_rH$protons of constituent amino acids in dipeptide solutions indicate the existence of two magnetically non-equivalent sites in solution. From this study, the structures of the five dipeptides have been confirmed by proton magnetic resonance spectra and it has been suggested that the structural change, conformation and sequence determination can be explored for oligopeptides by an analysis of proton magnetic resonance spectra.

• Journal of Biomedical and Translational Research
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• v.19 no.4
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• pp.130-139
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• 2018

This study aimed to analyze a high-performance liquid chromatography (HPLC) separation using a pentafluorophenyl column of parent drug hydroxychloroquine (HCQ) and its active metabolite, desethylhydroxchloroquine (DHCQ) applying to determine bioequivalence of two different formulations administered to patients. A rapid, simple, sensitive and specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for bioanalysis of HCQ and its metabolite DHCQ in human whole blood using deuterium derivative $hydroxychloroquine-D_4$ as an internal standard (IS). A triple-quadrupole mass spectrometer was operated using electrospray ionization in multiple reaction monitoring (MRM) mode. Sample preparation involves a two-step precipitation of protein techniques. The removed protein blood samples were chromatographed on a pentafluorophenyl (PFP) column ($50mm{\times}4.6mm$, $2.6{\mu}m$) with a mobile phase (ammonium formate solution containing dilute formic acid) in an isocratic mode at a flow rate of 0.45 mL/min. The standard curves were found to be linear in the range of 2 - 500 ng/mL for HCQ; 2 - 2,000 ng/mL for DHCQ in spite of lacking a highly sensitive MS spectrometry system. Results of intra- and inter-day precision and accuracy were within acceptable limits. A run time of 2.2 min for HCQ and 2.03 min for DHCQ in blood sample facilitated the analysis of more than 300 human whole blood samples per day. Taken together, we concluded that the assay developed herein represents a highly qualified technology for the quantification of HCQ in human whole blood for a parallel design bioequivalence study in a healthy male.

• The Southeast Asian review
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• v.24 no.2
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• pp.127-165
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• 2014

This article regards the phase of political confrontations in Thailand and Burma as a prolonged and inconclusive political struggle between national revolution forces and civil revolution forces. It argues that in Thai case, anti-monarchy constitutional revolution has led to a right-wing national revolution based on state nationalism consolidating capitalist economic system by Sarit's military coup, while in Burmese case, anti-British imperialism movement in colonial era has resulted in a left-wing national revolution grounded on state nationalism associating with socialist economic system by Ne Win's military coup. It is also interesting to note that the two cases experienced state nationalism denying autonomous civil society as a process of nation-building in spite of their contrasting ideologies. In both cases, it became inevitable to have national revolution forces clinging to official nationalism and state nationalism confronting with civil revolution forces seeking popular nationalism and liberal nationalism. In particular, unlike Burmese society, Thai society, without colonial history has never experienced a civil war mobilizing anti-colonial popular nationalism including ethnic revolt. This article considers Dankwart Rustow's argument that national unity as a background condition must precede all the other phases of democratization, but that otherwise its timing is irrelevant. In this context, Thai democratization without national unity which began earlier than Burmese is taking a backward step. For the time being, there would be no solution map to overcome severe political polarization between the right-wing national revolution forces defending official nationalism cum state nationalism and the civil revolution forces trying to go beyond official nationalism towards popular nationalism cum liberal nationalism. In contrast, paradoxically belated Burmese democratization has just taken a big leap in escaping from serious and inconclusive nature of political struggle between the left-wing national revolution forces to defend official nationalism cum state nationalism and civil revolution based on popular nationalism cum liberal nationalism towards a reconciliation phase in order to seek solutions for internal conflicts. The two case studies imply that national unity is not a background condition, but a consequence of the process of political polarization and reconciliation between national revolution forces and civil revolution forces.

• Nuclear Engineering and Technology
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• v.56 no.6
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• pp.1950-1958
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• 2024

For the pressurized water reactor two-step calculation, the traditional assembly homogenization and two-group neutron diffusion calculation have been widely used. When it comes to the core pin-by-pin simulation, many models and techniques are different and unsettled. In this paper, the homogenization methods based on the pin discontinuity factors and super homogenization factors are used to get the pin-cell homogenized parameters. The heterogeneous leakage model is applied to modify the infinite flux spectrum of the single assembly with reflective boundary condition and to determine the diffusion coefficients for the SP3 solver which is used in the core simulation. To reduce the environment effect of the single-assembly reflective boundary condition, the online method for the SPH factors updating is applied in this paper, and the functionalization of SPH factors based on the least-squares method will be pre-made alone with the table of the group constants. The fitting function will be used to update the thermal-group SPH factors with a whole-core pin-by-pin homogeneous solution online. The three-dimensional Watts Bar Nuclear Unit 1 (WBN1) problem was utilized to test the performance of pin-by-pin calculation. And numerical results have demonstrated that PWR pin-by-pin core calculation has more accurate results compared with the traditional assembly-homogenization scheme.