• Microbiology and Biotechnology Letters
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• v.20 no.6
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• pp.668-676
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• 1992

For the purpose of optimizing poly-l3-hydroxybutyrate (PHB) production from Alcaligenes eutrophus, two-stage fed-batch culture was adopted. In this system, specifk growth rate was maximized during the first stage whereas specific production rate was maximized during the second stage. The optimal concentrations of glucose and ammonium chloride were 16.6 and 0.54 g/I in the growth stage and 20.0 and 0.07 g/l in the production stage, respectively. Proportional feedback control considering time lag was suggested for PHB production process and a simulator was developed for real-time control purpose.

• Nuclear Engineering and Technology
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• v.56 no.2
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• pp.644-654
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• 2024

After the Tohoku earthquake and tsunami (Japan, 2011), regulatory efforts to mitigate external hazards have increased both the safety requirements and the total capital cost of nuclear power plants (NPPs). In these circumstances, identifying not only disaster robustness but also cost-effective capacity setting of NPPs has become one of the most important tasks for the nuclear power industry. A few studies have been performed to relocate the seismic capacity of NPPs, yet the effects of multiple hazards have not been accounted for in NPP capacity optimization. The major challenges in extending this problem to the multihazard dimension are (1) the high computational costs for both multihazard risk quantification and system-level optimization and (2) the lack of capital cost databases of NPPs. To resolve these issues, this paper proposes an effective method that identifies the optimal multihazard capacity of NPPs using a multi-objective genetic algorithm and the two-stage direct quantification of fault trees using Monte Carlo simulation method, called the two-stage DQFM. Also, a capacity-based indirect capital cost measure is proposed. Such a proposed method enables NPP to achieve safety and cost-effectiveness against multi-hazard simultaneously within the computationally efficient platform. The proposed multihazard capacity optimization framework is demonstrated and tested with an earthquake-tsunami example.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10a
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• pp.69-72
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• 1996

This paper considers a global resolution of kinematic redundancy under inequality constraints as a constrained optimal control. In this formulation, joint limits and obstacles are regarded as state variable inequality constraints, and joint velocity limits as control variable inequality constraints. Necessary and sufficient conditions are derived by using Pontryagin's minimum principle and penalty function method. These conditions leads to a two-point boundary-value problem (TPBVP) with natural, periodic and inequality boundary conditions. In order to solve the TPBVP and to find a global minimum, a numerical algorithm, named two-stage algorithm, is presented. Given initial joint pose, the first stage finds the optimal joint trajectory and its corresponding minimum performance cost. The second stage searches for the optimal initial joint pose with globally minimum cost in the self-motion manifold. The effectiveness of the proposed algorithm is demonstrated through a simulation with a 3-dof planar redundant manipulator.

• Korean Management Science Review
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• v.8 no.1
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• pp.91-108
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• 1991

This paper presents an efficient optimization algorithm for the crude oil tanker scheduling problem. The algorithm consists of two stages. In stage one, all the potentially optimal schedules (called 'candidate schedules') are generated from feasible schedules for each ship. In the second stage, a multiple ship scheduling problem is formulated as 0-1 integer programming problem considering only the those candidate schedules. The efficiency of the suggested algorithm was improved by exploiting the special structure of the formulation. The algorithm was illustrated by a numerical example and tested on practical ship scheduling problems.

• International Journal of Aerospace System Engineering
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• v.2 no.2
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• pp.29-33
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• 2015

The multidisciplinary design optimization (MDO) of a launch vehicle (LV) with a hybrid rocket engine (HRE) was carried out to investigate the ability of an HRE for a single-stage LV. The non-dominated sorting genetic algorithm-II (NSGA-II) was employed to solve two design problems. The design problems were formulated as two-objective cases involving maximization of the downrange distance over the target flight altitude and minimization of the gross weight, for two target altitudes: 50.0 km and 100.0 km. Each objective function was empirically estimated. Several non-dominated solutions were obtained using the NSGA-II for each design problem, and in each case, a trade-off was observed between the two objective functions. The results for the two design problem indicate that economical performance of the LV is limited with the HRE in terms of the maximum downrange distances achievable. The LV geometries determined from the non-dominated solutions were examined.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.03a
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• pp.330-339
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• 2008

Ground-based interceptors(GBI) comprise a major element of the strategic defense against hostile targets like Intercontinental Ballistic Missiles(ICBM) and reentry vehicles(RV) dispersed from them. An optimum design of the subsystems is required to increase the performance and reliability of these GBI. Propulsion subsystem design and optimization is the motivation for this effort. This paper describes an effort in which an entire GBI missile system, including a multi-stage solid rocket booster, is considered simultaneously in a Genetic Algorithm(GA) performance optimization process. Single goal, constrained optimization is performed. For specified payload and miss distance, time of flight, the most important component in the optimization process is the booster, for its takeoff weight, time of flight, or a combination of the two. The GBI is assumed to be a multistage missile that uses target location data provided by two ground based RF radar sensors and two low earth orbit(LEO) IR sensors. 3Dimensional model is developed for a multistage target with a boost phase acceleration profile that depends on total mass, propellant mass and the specific impulse in the gravity field. The monostatic radar cross section (RCS) data of a three stage ICBM is used. For preliminary design, GBI is assumed to have a fixed initial position from the target launch point and zero launch delay. GBI carries the Kill Vehicle(KV) to an optimal position in space to allow it to complete the intercept. The objective is to design and optimize the propulsion system for the GBI that will fulfill mission requirements and objectives. The KV weight and volume requirements are specified in the problem definition before the optimization is computed. We have considered only continuous design variables, while considering discrete variables as input. Though the number of stages should also be one of the design variables, however, in this paper it is fixed as three. The elite solution from GA is passed on to(Sequential Quadratic Programming) SQP as near optimal guess. The SQP then performs local convergence to identify the minimum mass of the GBI. The performance of the three staged GBI is validated using a ballistic missile intercept scenario modeled in Matlab/SIMULINK.

• Environmental Engineering Research
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• v.8 no.5
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• pp.259-272
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• 2003

• Journal of the Korean Operations Research and Management Science Society
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• v.31 no.1
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• pp.1-13
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• 2006

In this paper we consider a design problem of a cyclic queueing network with two stages, each with a local buffer of limited capacity. Based on the theory of reversibility and product-form solution, we derive the throughput function of the network as a key performance measure to maximize. Two cases are considered. In case each stage consists of a single server, an optimal allocation policy of a given buffer capacity and work load between stages as well as the optimal number of customers is identified by exploiting the properties of the throughput function. In case each stage consists of multiple servers, the optimal policy developed for the single server case doesn't hold any more and an algorithm is developed to allocate with a small number of computations a given number of servers, buffer capacity as well as total work load and the total number of customers. The differences of the optimal policies between two cases and the implications of the results are also discussed. The results can be applied to support the design of certain manufacturing and computer/communication systems.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.5 s.236
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• pp.625-632
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• 2005

This paper describes the shape optimization of a stator blade in a single-stage transonic axial compressor. The blade optimization has been performed using response surface method and three-dimensional Navier-Stokes analysis. Two shape variables of the stator blade, which are used to define a stacking line, are introduced to increase an adiabatic efficiency. Data points for response evaluations have been selected by D-optimal design, and linear programming method has been used for an optimization on a response surface. Throughout the shape optimization of a stator blade, the adiabatic efficiency is increased to 5.8 percent compared to that of the reference shape of the stator. The increase of the efficiency is mainly caused by the pressure enhancement in the stator blade. Flow separation on the blade suction surface of the stator is also improved by optimizing the stator blade. It is noted that the optimization of the stator blade is also useful method to increase the adiabatic efficiency in the axial compressor as well as the optimization of a rotor blade, which is widely used now.

• Journal of the Korean Wood Science and Technology
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• v.41 no.2
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• pp.111-122
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• 2013

The steam explosion-chemical pretreatment is a more effective wood pretreatment technique than the conventional physical pretreatment by accelerating reactions during the pretreatment process. In this paper, two-stage pretreatment processes of hardwood were investigated for its enzymatic hydrolysis and the succinic acid yield from the pretreated solid. The first stage pretreatment was performed under conditions of low severity to optimize the amount of solid recovery. In the second stage pretreatment washed solid material from the first stage pretreatment step was impregnated again with chemical (alkaline or chlorine-based chemicals) to remove a portion of the lignin, and to make the cellulose more accessible to enzymatic attack. The effects of pretreatment were assessed by enzymatic hydrolysis and fermentation, after the two stage pretreatments. Maximum succinic acid yield (16.1 g $L^{-1}$ and 77.5%) was obtained when the two stage pretreatments were performed at steam explosion -3% KOH.