• Journal of Fisheries and Marine Sciences Education
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• v.25 no.2
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• pp.301-306
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• 2013

In this paper, cycle performance analysis of two-stage compression and two-stage expansion refrigeration system using alternative freon refrigerants is presented to offer the basic design data for the operating parameters of the system. Alternative freon refrigerant for freon refrigerant R22 were used as working fluids in this study. The operating parameters considered in this study included evaporation temperature, condensation temperature, subcooling degree, superheating degree, and mass flow rate ratio of inter-cooler. The main results were summarized as follows : The COP of two-stage compression and two-stage expansion refrigeration system increases with the increasing subcooling degree and mass flow rate ratio of inter-cooler, but decreases with the increasing evaporating temperature, condensing temperature and superheating degree. Therefore, subcooling degree, mass flow rate ratio of inter-cooler of two-stage compression and two-stage expansion refrigeration system using alternative freon refrigerants have an effect on COP of this system.

• Journal of Power System Engineering
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• v.13 no.6
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• pp.70-75
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• 2009

In this paper, cycle performance analysis of R744($CO_2$) two-stage compression and one-stage expansion refrigeration system is presented to offer the basic design data for the operating parameters of the system. The operating parameters considered in this study include superheating degree, compressor efficiency, gas cooling pressure, mass flowrate ratio, outlet temperature of gas cooler and evaporating temperature in the carbon dioxide two-stage refrigeration cycle. The main results were summarized as follows : The cooling capacity of two-stage compression and one-stage expansion refrigeration system increases with the increasing superheating degree, compressor efficiency and gas cooling pressure, but decreases with the increasing mass flowrate ratio and evaporating temperature. The compression work of two-stage compression and one-stage expansion refrigeration system increases with the increasing superheating degree, outlet temperature of gas cooler, gas cooling pressure and evaporating temperature, but decreases with the increasing compressor efficiency and mass flowrate ratio. The COP of two-stage compression and one-stage expansion refrigeration system increases with the increasing compressor efficiency, but decreases with the increasing superheating degree, gas cooling pressure, mass flowrate ratio and evaporating temperature. Therefore, superheating degree, compressor efficiency, gas cooling pressure, mass flowrate ratio, outlet temperature of gas cooler and evaporating temperature of R744($CO_2$) two-stage compression and one-stage expansion refrigeration system have an effect on the cooling capacity, compressor work and COP of this system.

• Journal of Power System Engineering
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• v.19 no.6
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• pp.82-88
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• 2015

In this paper, cycle performance analysis of two-stage compression and one-stage expansion refrigeration system applied various refrigerants is presented to offer the basic design data for the operating parameters of the system. The operating parameters considered in this study include degree of superheating and subcooling, compressor efficiency, evaporation temperature, condensing temperature, mass flow rate ration into inter-cooler, effectiveness of internal heat exchanger. The main results were summarized as follows : The COP of two-stage compression and 1-stage expansion refrigeration system increases with the increasing subcooling, mass flow rate ration of inter-cooler, evaporation temperature, but decreases with the increasing condensing temperature and superheating degree. Therefore, subcooling degree, mass flow rate ratio of inter-cooler of two-stage compression and 1-stage expansion using substitute refrigerant have an effect on COP of this system. The COP of alternative refrigerants was higher than the COP of R22 in this study, although the COP of some mixed refrigerants were lower than COP of R22.

• Journal of Advanced Marine Engineering and Technology
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• v.41 no.3
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• pp.191-196
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• 2017

Owing to the harmful environmental effects of HCFC and CFC refrigerants discovered in the late 20th century, the need for environmentally friendly refrigerants such as $CO_2$ in cooling systems has increased. Air-source $CO_2$ heat pumps that utilize ambient heat in cold winter are less efficient because of a higher evaporation temperature, and it is difficult to manufacture the components of the heat pump owing to a super critical pressure of over 130 bar. This research aims to overcome these disadvantages and improve energy efficiency by introducing a new lower-pressure $CO_2$ auto-cascade heat pump system. $CO_2$-R32 zeotropic refrigerants were considered for two-stage expansion and effective cooling heat exchanging system configurations of the new auto-cascade heat pump. The results indicated that the efficiency of the two-stage expansion system was higher than that of the original one-stage expansion system. Furthermore, the two-stage expansion system showed significant performance improvements when the two-stage expansion stage from highest pressure of 70bar, intermediate expansion pressure of 25bar, and final low pressure of 10bar is applied. The COP of the new two-stage auto-cascade system (2.332) was 43.15% higher than that of the present simple auto-cascade system (1.629). Refrigerants having an evaporation temperature of $-10^{\circ}C$ or lower can be obtained that can be easily evaporated in an evaporator even at a low temperature.

• 제어로봇시스템학회:학술대회논문집
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• 1997.10a
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• pp.1758-1761
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• 1997

The problem of long range capacity expansion planing for chemical processing network under uncertain demand forecast secnarios is addressed. This optimization problem involves capactiy expansion timing and sizing of each chemical processing unit to maximize the expected net present value considering the deviation of net present values and the excess capacity over a given time horizon. A multiperiod mixed integer nonlinear programming optimization model that is both solution and modle robust for any realization of demand scenarios is developed using the two-stage stochastic programming algorithm. Two example problems are considered to illustrate the effectiveness of the model.

• Transactions of the Korean hydrogen and new energy society
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• v.30 no.2
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• pp.188-192
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• 2019

Comparative studies between single- and two-stage expansion process using LNG cold heat have been performed for a closed Rankine power generation cycle. PRO/II with PROVISION release 10.0 from Schneider Electric Company was used, and the Peng-Robinson equation of state model with Twu's alpha function was selected for the modeling and optimization of the power generation cycle using LNG cold heat. In two-stage power generation cycle, 6.7% more power was obtained compared to that of single-stage power generation cycle through the optimization works.

• Archives of Plastic Surgery
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• v.43 no.2
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• pp.197-203
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• 2016

Background The aim of unilateral breast reconstruction after mastectomy is to craft a natural-looking breast with symmetry. The latissimus dorsi (LD) flap with implant is an established technique for this purpose. However, it is challenging to obtain adequate volume and satisfactory aesthetic results using a one-stage operation when considering factors such as muscle atrophy, wound dehiscence and excessive scarring. The two-stage reconstruction addresses these difficulties by using a tissue expander to gradually enlarge the skin pocket which eventually holds an appropriately sized implant. Methods We analyzed nine patients who underwent unilateral two-stage LD reconstruction. In the first stage, an expander was placed along with the LD flap to reconstruct the mastectomy defect, followed by gradual tissue expansion to achieve overexpansion of the skin pocket. The final implant volume was determined by measuring the residual expander volume after aspirating the excess saline. Finally, the expander was replaced with the chosen implant. Results The average volume of tissue expansion was 460 mL. The resultant expansion allowed an implant ranging in volume from 255 to 420 mL to be placed alongside the LD muscle. Seven patients scored less than six on the relative breast retraction assessment formula for breast symmetry, indicating excellent breast symmetry. The remaining two patients scored between six and eight, indicating good symmetry. Conclusions This approach allows the size of the eventual implant to be estimated after the skin pocket has healed completely and the LD muscle has undergone natural atrophy. Optimal reconstruction results were achieved using this approach.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2003.06a
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• pp.733-736
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• 2003

This paper presents two systems of two-stage electrohydraulic servovalve with a nozzle-flapper pilot stage, which is controlled by stack-type piezoelectric elements. Two flapper moving mechanisms proposed in this research can compensate for the hysteresis problem and thermal expansion of the piezoelectric elements. The experimental results show that the first flapper moving mechanism has the frequency response of over 500 Hz and the second one has the response of over 600 Hz. And the first simplified servovalve system rising the first flapper moving mechanism has the frequency response of about 150 Hz, and the second system has the response of about 300 Hz at the supply pressure of 210 bar

• KOREAN JOURNAL OF CROP SCIENCE
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• v.44 no.4
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• pp.391-395
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• 1999

Barnyardgrass had relatively higher growth vigor at the earlier growth stage than inbred rice did, showing the 2 fold higher $\alpha$-amylase activity during the periods of germination and large leaf area Expansion with high net photosynthetic rate at the earlier autotrophic stage, but it performed weak growth at the late growth stage. However, the hlybrid rice Shanyou 63 had significantly higher $\alpha$-amylase activity and net photosynthetic rate than that of barnyardgrass, exhibiting heterosis for two physiologica1 traits during the germination (6~12 days) and autotrophic phase, respectively. Accordingly, hybrid rice, Shanyou 63, exhibited heterotic effect at the early growing stage when were presented with barnyardgrass. Shanyou 63 exhibited stronger tillering ability, faster leaf area expansion and higher net photosynthetic rate than those of barnyardgrass.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.44 no.4
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• pp.182-190
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• 2018

Objectives: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide. Inconsistency in various histopathologic features for predicting nodal metastasis and overall prognosis and a better understanding of molecular mechanisms of tumourigenesis have shifted the focus to a search for more definitive predictive markers. To identify the role of two immunohistochemical (IHC) markers, E-cadherin and cyclin D1, as predictive markers of aggressiveness in HNSCC and to assess clonal expansion of tumour cells. Materials and Methods: A total of 66 cases of HNSCC with neck node dissection were studied. IHC was performed on primary tumour sections and lymph nodes showing metastatic deposits. Histopathological parameters such as tumour grade and TNM stage together with nodal status were compared according to expression of the two markers. Fischer's chi-square test was used to assess the correlation between the two markers and histopathological parameters. Results: Out of 66 cases studied, 37 showed LN metastasis. Most of the patients were male, and the most common tumour site was buccal mucosa. We found a significant association between loss of E-cadherin and node metastasis (P<0.001) and higher TNM stage (P<0.001). Cyclin D1 overexpression was significantly associated with only nodal metastasis (P=0.007). No significant association with tumour grade was found for either marker. The subgroup of E-cadherin loss with cyclin D1 overexpression was associated with the maximum incidence of nodal metastasis and higher TNM stage, highlighting the importance of using a combination of these two markers. A significant association was noted between the expression of markers at the primary site and at nodal deposits, indicating clonal expansion. Conclusion: A combination of the two markers E-cadherin and cyclin D1 can predict prognosis in HNSCC, although tumour heterogeneity may affect this association in some cases.