• Archives of design research
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• v.11 no.2
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• pp.215-226
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• 1998

As late as middle of 1980s, what was referred to as new model cars consisted, on the premise of a standardized packaging layout, principally of the endeavor to transform their style images by changing little by little the form of layouts almosts similar to or with larger bodies than those of the old model ones. Afterwards even in the period of competition of engeineering and mechanical body styles for reducing fuel cost and improving comfortability in riding, the standardized packaging layout did not change visibly, simply trying to ameliorating commercialism through high output and high efficacy on the engineering part. Today the sudden prevalent motorization in every walk of life has brought about the development of the car industry, thus producing surplus supply and technical standardization. This phenomenon of technical standardization leads the concept of the renovation of car design to a way quite different from that of the past and so may be said to be confronted with an era that requires genuine-sense car design in a way. It seems that interior design plans are of much more importance than external shapes. This is because the effort for enhancing comfortability to keep car passengers' needs of transportation is one of the essences of car design. The objective of this study consists in inquiring into how to plan motorcar interior design, an essential prerequisite in determining the external or of a car, obtaining data needed via analysis of interior design plans of the car models that have won favorable criticism from consumers, thus contributing to the use of the data obtained for reference in car design activities in a genuine sense.

• Transactions of the Korean Society of Mechanical Engineers
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• v.11 no.1
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• pp.53-62
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• 1987

High power lasers provide a controllable and precise energy source in surface transformation hardening. A careful control of the process is needed in order that the surface layer of the material reaches the austenizing temperature, but that it does not melt. In order to achieve this the results of theoretical and experimental studies on the laser surface hardening of a medium carbon steel are described. A two-dimensional computer program, which can be used generally for the determination of transient temperature distributions in welding and heat treatment, was established on the basis of the finite element method. For the confirmation of the accuracy of the numerical analysis, a medium carbon steel (SM 45C) of 5mm thickness was heat-treated with a 1kW CW CO$_{2}$ laser machine, while the traverse speed and the distance from the focal point (defocused distance) were varied. Experimental and numerical results showed a similar tendency in correlations between the hardened zone shape and the process parameters. With increasing beam spot diameter the width and depth of the hardened zone increased for relatively small beam spot diameters, but decreased rapidly after reaching the maximum value, while with increasing traverse speed the width and depth of the hardened zone decreased monotonously. Too small beam spot diameters are to be avoided, since the surface melting would lower the surface hardness and produce an uneven surface which may be unacceptable because of the possible requirement for subsequent machining. It could be observed that for a given traverse speed and laser power input there exists a optimal range of the beam spot diameter, which produce a large width of the hardened zone but no melting on the surface.

• Journal of Animal Science and Technology
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• v.59 no.7
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• pp.16.1-16.6
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• 2017

Background: This study was performed to investigate the impact of exogenous ghrelin on the pancreatic ${\alpha}$-amylase outputs and responses of pancreatic proteins to ghrelin that may relate to pancreatic exocrine. Methods: Sprague-Dawley male rats (9 weeks old, $300{\pm}10g$) were injected with ghrelin via intraperitoneal (i.p.) infusion at dosage of 0, 0.1, 1.0 and $10.0{\mu}g/kg$ body weight (BW), respectively. The plasma ghrelin and cholecystokinin (CCK) level were determined using enzyme immunoassay kit; the mRNA expression of ghrelin receptor ($GHSR-1{\alpha}$) and growth hormone (GH) receptor were assessed by reverse transcription PCR; the expressions of pancreatic ${\alpha}$-amylase activity, extracellular-signal-regulated kinases (ERK), phosphorylated extracellular-signal-regulated kinases (pERK) and c-Jun N-terminal kinase (JNK) were evaluated by western blotting; moreover the responses of pancreatic proteins to ghrelin were analyzed using the two-dimensional gel electrophoresis system. Results: The exogenous ghrelin (1.0 and $10.0{\mu}g/kg\;BW$) elevated the level of plasma ghrelin (p < 0.05), and suppressed the expression of pancreatic ${\alpha}$-amylase at a dose of $10.0{\mu}g/kg\;BW$ (p < 0.05). No difference in the level of plasma CCK was observed, even though rats were exposed to any dose of exogenous ghrelin. In addition, a combination of western blot and proteomic analysis revealed exogenous ghrelin ($10.0{\mu}g/kg\;BW$) induced increasing the JNK and ERK expressions (p < 0.05) and four proteins such as Destrin, Anionic trypsin-1, Trypsinogen, and especially eukaryotic translation initiation factor 3 in rat pancreas. Conclusions: Taken together, exogenous ghrelin by i.p. infusion plays a role in the pancreatic exocrine secretion via mitogen-activated protein kinase signaling pathway.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.35 no.6
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• pp.609-616
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• 2017

National Geographic Information Institute has established a plan that preoccupies UCPs (Unified Control Points) at 2~3km intervals in urban areas by considering the distance between existing UCPs by satellite images and aerial photographs in 2015. In this study, we discussed the method of selecting the locations of optimal UCPs by simulating GPS reception environment in candidate sites for UCPs using GIS. For this purpose, we selected new candidate sites for installing UCPs using satellite images and aerial photographs, and analyzed the GPS reception environment by calculating the visibility distance from buildings around UCPs using GIS skyline analysis. The number of and the arrangement of visible satellites that are capable of GPS satellite reception from the viewpoint of sky view were showed by GIS skyline analysis. Quality evaluation results of GPS observation data were compared with average PDOP calculated from hourly PDOP and TEQC in two points of Sungkyunkwan University during 8 hours. As a result of GPS reception environment using GIS, if the PDOP increases, the data acquisition rate is lowed, and the multipath error and the cycle slip are increased. Thus, this study verified that the quality of GPS observation data can be secured by constructing three-dimensional spatial information and simulating PDOP when preoccupying multiple UCPs using GIS.

• Therapeutic Science for Rehabilitation
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• v.3 no.2
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• pp.5-48
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• 2014

Introduction : One of the important domains in OT is performance skills which include sensory perceptual skills, motor and praxis skills, emotional regulation skills, cognitive skills, and communication/social skills. All of these skills are support ed by integrated neurological processes. Body : Stereology robust tool when employed to investigate morphological changes in neurons, cortex area, and specific parts of brain involved in special brain function. Stereology is an interdisciplinary field focused or analyzing biological tissue with the three-dimensional interpretation of planer sections by using estimating method and mathematically unbiased sampling. With the unbiased stereological method based on probability theory, researchers can estimate morphological and anatomical changes in biological reference areas accurately and efficiently. Changes in anatomical and cytoarchitectural parameters, such as volume, number, and length, affect specific brain function related to the brain area. Occupational therapists provide treatment to improve functions for participation of occupation in neurological disorder. The functional improvements in neurological disorder reflect neurobiological changes because functional difficulties, such as motor cognitive disorder, are due to neurological disturbances. Thus, combination of two kinds of evidence, neurological changes and functional improvement, provide fundamental evidence for OT intervention in neurological disorder. Even though most of stereological studies are in animal model and in postmortem human because of practical and ethical issues, stereology provides fundamental knowledge to support OT theory and practice. Conclusion : Therefore, stereology informs translation from neuroscience to OT based on structure-function relationship in performance skills and experience-dependent neural plasticity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.6
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• pp.1652-1660
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• 2004

Apoptosis of vascular smooth muscle cells(VSMCs) is essential in atherogenesis, being a factor that modulates its early progression rather than a terminal event in the course of the disease. Various stimuli, including oxide lipoproteins, altered hemodynamic stress and free radical, can induced VSMCs apoptosis in vitro. The protective effects of Sophorae Radix (SR) on apoptotic cell death induced by H₂O₂ were investigated in VSMCs. The viability of VSMCs was markedly decreased by H₂O₂. Sophorae Radix protected the H202-induced apoptotic death of VSMCs, which was characterized as nuclear fragmentation and increase of sub-G0/G1 fraction .. Sophorae Radix decreased the activation of caspase-3 like protease induced by H₂O₂ and recovered control level from H202-induced PARP, Bak, Bcl-XL and mitochondrial membrane potential. These results suggest that Sophorae Radix protected VSMCs apoptotic death induced by H₂O₂ via inactivation of caspase-3 and modulation of mitochondrial function. Also, the expression profile of proteins by using two-dimensional (2-D) gel electrophoresis was screened. Future investigations will need to explore the use of an anti atherosclerotic therapy of Sophorae Radix, which relies on inhibition of the proapoptotic activation of the vascular smooth muscle cells.

• Tunnel and Underground Space
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• v.16 no.1 s.60
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• pp.26-37
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• 2006

This study addresses the applicability of box fractal dimension, $D_B$, as an index of statistical homogeneity of fractured rock mass. The box-count method's capability in quantifying the combined effect of fracture density and size distribution is examined systematically. Total of 129 two-dimensional fracture configurations were generated based on different combinations of fracture size distribution and fracture density. $D_B$was calculated for the generated fracture network systems using the box-counting method. It was found that was standard deviation of trace length and fracture orientation have no effect on calculated $D_B$. The estimated $D_B$ was found to increase with increasing total density and/or mean trace length. To explore the field applicability of this study, the statistical homogeneity of fractured rock mass was investigated at the rock slope and the underground facility using the box-counting method as well as conventional contingency table analysis. The results obtained in this study clearly show that the methodologies given in this paper have the capability of determining the statistical homogeneity of fractured rock mass.

• Korean Journal of Applied Biomechanics
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• v.12 no.2
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• pp.215-227
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• 2002

The purpose of this study was to investigate propulsive time and kinematic variables on the three different kinds of the basketball wheelchairs in each play position for eight abled basketball wheelchair players. Kinematic data were collected by a video camera for two-dimensional analysis. The wheelchairs for the guard position showed the fastest in total propulsive time. The wheelchairs for the center position revealed the slowest in the phase of the change of the direction. The wheelchair for the guard position which shows fast movement velocity demonstrated closer hand contact with TDC(Top Dead Center). The wheelchair for the center position revealed the largest extension of the elbow and flexion of the trunk at handrim contact. The wheelchair for the guard position which has the lowest seat height presented larger elbow angle and trunk angle. The wheelchair for the guard position produced more fast trunk angular velocity than the wheelchair for other positions.

• Journal of Korea Water Resources Association
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• v.40 no.4
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• pp.335-343
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• 2007

Drought characteristics need to be preceded before establishing a drought mitigation plan. In this study, using a Standardized Precipitation Index (SPI), a hydrologic drought was defined as an event during which the SPIs are continuously below a certain truncation level. Then, a methodology of drought frequency analysis was performed to quantitatively characterize droughts considering drought duration and severity simultaneously. The theory of runs was used to model drought recurrence and to determine drought properties like duration and severity. Short historical records usually do not allow reliable bivariate analyses. However, more than hundred years of precipitation data (1770 ${\sim}$ 1907) collected in Chosun Kingdom Age using an old Korean rain gage called Chukwooki can provide valuable information about past events. It is shown that a bivariate gamma distribution well represented the joint probabilistic properties of Korean drought duration and severity. The overall results of this study show that the proposed bivariate drought frequency analysis overcomes the drawbacks of the conventional univariate frequency analysis by providing a consistent representation of the drought recurrent property.

• Journal of Korea Water Resources Association
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• v.44 no.7
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• pp.553-563
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• 2011

According to the improvement of computer's performance, the development of Geographic Information System (GIS), and the activation of offering information, a distributed model for analyzing runoff has been studied a lot in recently years. The distribution model is a theoretical and physical model computing runoff as making target basin subdivided parted. In the distributed model developed by this study, the volume of runoff at the surface flow is calculated on the basis of the parameter determined by landcover data and a two-dimensional diffusion wave equation. Most of existing runoff models compute velocity and discharge of flow by applying Manning-Strickler's mean velocity equation and Manning's roughness coefficient. Manning's roughness coefficient is not matched with dimension and ambiguous at computation; Nevertheless, it is widely used in because of its convenience for use. In order to improve those problems, this study developed the runoff model by applying not only Manning-Strickler's equation but also Chezy's mean velocity equation. Furthermore, this study introduced a power law of exponential friction factor expressed by the function of roughness height. The distributed model developed in this study is applied to 6 events of fan-shape basin, oblong shape test basin and Anseongcheon basin as real field conditions. As a result the model is found to be excellent in comparison with the exiting runoff models using for practical engineering application.