• 제목/요약/키워드: Two stage approach

검색결과 556건 처리시간 0.029초

Nuclear magnetic resonance-based metabolomics analysis and characteristics of beef in different fattening periods

  • Jeong, Jin Young;Baek, Youl-Chang;Ji, Sang Yun;Oh, Young Kyun;Cho, Soohyun;Seo, Hyun-Woo;Kim, Minseok;Lee, Hyun-Jeong
    • Journal of Animal Science and Technology
    • /
    • 제62권3호
    • /
    • pp.321-333
    • /
    • 2020
  • Beef quality is influenced by the fattening period. Therefore, meat metabolomics profiles from the different fattening periods (e.g., short-term vs. long-term) were analyzed for identify potential indicators using nuclear magnetic resonance. Additionally, blood, free fatty acid, sensory, and mineral compositions in Korean steers were determined. Blood, free fatty acid, and mineral concentrations showed significant differences between short-term and long-term groups that were fed different diets. However, there were no sensory differences in the two fattening groups. Additionally, the metabolic profiles of meats were clearly separated based on multivariate orthogonal partial least square discriminant analysis. Six metabolites of variable importance in the projection plot were identified and showed high sensitivity as candidate markers for meat characteristics. In particular, lactate, carnosine, and creatine could be directly linked to scientific indicators of the fattening stage (31 vs. 28 mo) of meat. Our findings suggest that the metabolomics approach could be a powerful method for the detection of novel signatures underlying the managing period of beef.

Buccal infiltration injection without a 4% articaine palatal injection for maxillary impacted third molar surgery

  • Sochenda, Som;Vorakulpipat, Chakorn;Kumar, K C;Saengsirinavin, Chavengkiat;Rojvanakarn, Manus;Wongsirichat, Natthamet
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
    • /
    • 제46권4호
    • /
    • pp.250-257
    • /
    • 2020
  • Objectives: Palatal infiltration is the most painful and uncomfortable anesthesia technique for maxillary impacted third molar surgery (MITMS). This approach could cause patients distress and aversion to dental treatment. The aim of this study was to evaluate the anesthetic efficacy of a buccal infiltration injection without a palatal injection in MITMS. Materials and Methods: This prospective research study was a crossover split mouth-randomized controlled trial. Twenty-eight healthy symmetrical bilateral MITMS patients (mean age, 23 years) were randomly assigned to two groups. Buccal infiltration injections without palatal injections were designated as the study group and the buccal with palatal infiltration cases were the control group, using 4% articaine and 1:100,000 epinephrine. The operation started after 10 minutes of infiltration. Pain assessment was done using a visual analogue scale and a numeric rating scale after each injection and extraction procedure. Similarly, the success rate, hemodynamic parameters, and additional requested local anesthetic were assessed. Results: The results showed that the pain associated with local anesthetic injections between both groups were significantly different. However, the success rates between the groups were not significantly different. Postoperative pain was not significant between both groups and a few patients requested an additional local anesthetic, but the results were not statistically significant. For hemodynamic parameters, there was a significant difference in systolic pressure during incision, bone removal, and tooth elevation. In comparison, during the incision stage there was a significant difference in diastolic pressure; however, other steps in the intervention were not significantly different between groups. Conclusion: We concluded that buccal infiltration injection without palatal injection can be an alternative technique instead of the conventional injection for MITMS.

Effect of soil in controlling the seismic response of three-dimensional PBPD high-rise concrete structures

  • Mortezaie, Hamid;Rezaie, Freydoon
    • Structural Engineering and Mechanics
    • /
    • 제66권2호
    • /
    • pp.217-227
    • /
    • 2018
  • In the last decades, valuable results have been reported regarding conventional passive, active, semi-active, and hybrid structural control systems on two-dimensional and a few three-dimensional shear buildings. In this research, using a three-dimensional finite element model of high-rise concrete structures, designed by performance based plastic design method, it was attempted to construct a relatively close to reality model of concrete structures equipped with Tuned Mass Damper (TMD) by considering the effect of soil-structure interaction (SSI), torsion effect, hysteresis behavior and cracking effect of concrete. In contrast to previous studies which have focused mainly on linearly designed structures, in this study, using performance-based plastic design (PBPD) design approach, nonlinear behavior of the structures was considered from the beginning of the design stage. Inelastic time history analysis on a detailed model of twenty-story concrete structure was performed under a far-field ground motion record set. The seismic responses of the structure by considering SSI effect are studied by eight main objective functions that are related to the performance of the structure, containing: lateral displacement, acceleration, inter-story drift, plastic energy dissipation, shear force, number of plastic hinges, local plastic energy and rotation of plastic hinges. The tuning problem of TMD based on tuned mass spectra is set by considering five of the eight previously described functions. Results reveal that the structural damage distribution range is retracted and inter-story drift distribution in height of the structure is more uniform. It is strongly suggested to consider the effect of SSI in structural design and analysis.

절차적 방법을 이용한 다관절체의 대화형 동작생성 (Interactive Animation of Articulated Bodies using a Procedural Method)

  • 배희정;백낙훈;이종원;유관우
    • 한국정보과학회논문지:시스템및이론
    • /
    • 제28권12호
    • /
    • pp.620-631
    • /
    • 2001
  • 게임이나 가상 현실 등의 대화형 처리에서 다관절체의 동작을 실시간으로 처리할 필요성이 증가하고 있다. 최근에는 다관절체의 동작을 사실적으로 표현하기 위하여, 제약 동역학(constrained dynamics)방법들이 사용되고 있으나, 이 방법들은 사용자의 요구가 빈번한 가상 공간에서 다관절체의 동작을 실시간으로 처리하기는 곤란하다. 본 논문에서는 다관절체의 동작을 비교적 사실적이면서도 빠르게 생성하기 위한 절차적 방법(procedural method)을 제안한다. 이 방법에는 다관절체를 구성하는 세그먼트들의 동역학적 움직임과 조인트에서의 기하학적 제약 조건을 따로 처리함으로써, 복잡한 선형 시스템의 풀이 과정을 피하였다. 결과적으로 본 본문이 제안하는 방법은 필요한 계산량을 줄임으로써 실시간 처리가 가능하다. 제안하는 방법의 구현 결과로서, 일반적인 PC 환겨에서 인형 형태 다관절체의 동작을 대화형으로 실시간에 처리할 수 있음을 보인다. 이러한 방법들은 가상 공간에서의 캐릭터 애니메이션 등에 적용할 수 있을 것으로 기대된다.

  • PDF

기술융합이 적용된 현대장신구사례 및 응용연구 (nfc tag이 적용된 반지를 중심으로) (A Research and application of modern ornaments applied with technology convergence (focus on ring with NFC tag applied))

  • 황선욱
    • 디지털융복합연구
    • /
    • 제18권8호
    • /
    • pp.459-467
    • /
    • 2020
  • 현대 장신구를 제작하는 작가의 입장에서 초연결시대속 현대장신구의 미래를 보고자 했다. 특히 그중 하나인 정보통신 기술, 그중에서도 nfc Tag을 응용한 기술융합의 실제적 방안을 찾고자 한다. 그 실제적인 접근을 위해 현재 nfc Tag기술이 활용된 상업적반지제품들의 실예를 살펴본 후 이후 공방에서 제작되는 현대장신구에도 적용가능한 실제적 방법을 찾고자 했다. 그 결과 비교적 융합이 자유롭지만 기술적 활용도가 제한되는 매몰법과 기술적 활용도는 높지만 디자인 기획 단계부터 융합을 고려해야하는 조립법의 현실적 대안을 도출하였으며 특히 그중 실제적용에 차이가 있을 수 있는 매몰법을 개념만이 아니라 샘플제작을 통해 기술적용에 있어 필요한 요소와 주의점등을 기술하였다.

고속 페이징 시스템을 위한 FLEX 프로토콜 신호처리기의 구현 (Implementation of a FLEX Protocol Signal Processor for High Speed Paging System)

  • 강민섭;이태응
    • 대한전자공학회논문지SD
    • /
    • 제38권1호
    • /
    • pp.69-78
    • /
    • 2001
  • 본 논문은 휴대용 고속 페이징 시스템을 위한 FLEXTM 프로토콜 신호 처리기의 설계 및 FPGA 구현에 관한 것이다. 본 논문에서는 A/D 변환기의 입력 단에서 수신된 interleaved 4-level 비트 심볼 데이터의 동기를 위한 심볼 동기 알고리듬과 (31,21)BCH 부호에 대해 실시간 2중 오류정정이 가능한 개선된 복호 알고리듬을 제안한다. 설계된 프로토콜 신호처리기는 6개의 기능 모듈로 구성되어 있으며, 각 모듈은 VHDL(VHSIC Hardware Description Language)로 모델링을 행하였다. 제안된 프로토콜 신호기는 Axil-320 워크스테이션 상에서 Synopsys/sup TM/툴을 이용하여 기능 시뮬레이션 및 논리합성(Altera 10K 라이브러리 이용)을 수행하였다. 논리합성 결과 전체 셀의 수는 약 2,631이었다 또한, 설계된 FPGA 칩의 설계검증을 위하여 Altera MAX+ PLUS Ⅱ 상에서 타이밍 시뮬레이션을 수행하였다. PCB 상에서 testbed를 구축한 후, Logic Analyzer를 이용하여 제작된 FPGA 칩의 동작상태를 확인하였고, 실험을 통하여 제작된 칩이 정확히 동작함을 확인하였다.

  • PDF

베이비붐세대의 디지털라이프 지수 (Digital Life Index of Babyboom Generation)

  • 권순재;김미령
    • 한국정보시스템학회지:정보시스템연구
    • /
    • 제23권1호
    • /
    • pp.161-184
    • /
    • 2014
  • Our study measures the Digital Life Index (DLI) of baby boomers by considering the utilization of digital devices in their everyday life. The study was conducted by implementing the following three-step approach: (1) development of survey questions and data collection; (2) build Digital Life Index (DLI) model and lastly; (3) empirical analysis using the Digital Life Index (DLI). In the first stage in order to develop the survey questions to measure the digital index, two surveys were conducted. For the first preliminary survey, it was done based on the existing literatures which enabled this investigation through FGI analysis involving real professionals. The second survey was conducted by commissioning a specialized external firm. In this survey, a total of 400 data was collected to verify the validity and objectivity of the data sample. The data gathered through the survey questions was used to develop the digital index. Firstly, the appropriate factors were extracted by conducting factor analysis. This factor analysis validates and verifies the factors which are appropriate in measuring Digital Life Index (DLI). The derived factors are broadly divided into five main factors. The first factor describes the possession, purchase and use of digital device (x1). Meanwhile, the second factor describes the digital device's software (x2) and the third factor describes the participation in utilizing digital device (x3). The fourth factor describes the utilization of digital device in human personal relationship (x4) and lastly, the fifth factor describes the effect of digital device in everyday life and work environment (x5). Secondly, the digital index model was developed. The variables to represent the Digital Life Index (DLI) are ${\chi}1t,{\chi}2t,{\chi}3t,{\chi}4t$ and ${\chi}5t$. Furthermore, as experience in using the digital index grows overtime, the growth can be represented by the "S" shape. Based on the results, Digital Life Index(DLI) is distributed with the highest point at 90.3 and the lowest point at 25.9.

119와 1339에 접수되는 중독 상담 정보의 변화 비교: 응급의료정보센터(1339) 통합 이후의 소방구급상황센터(119)에서의 병원 전 독성 물질 노출자료 현황 분석 (Changes of Poison Data Characteristics Collected from Telephone Response in 1339 and 119: Discrepancy in Characteristics of Post-toxin Exposure Data Obtained through Telephone Counselling Provided by 1339 and 119)

  • 박광훈;박종수;이성우;김수진;한갑수;이의중
    • 대한임상독성학회지
    • /
    • 제15권2호
    • /
    • pp.116-121
    • /
    • 2017
  • Purpose: The aim of this study was to compare the toxicologic profiles and outcome of poisoned patients by comparing the data obtained through telephone counselling, each provided by emergency medical information center (1339) and emergency dispatch center (119). Methods: We analyzed the telephone-based poison exposure data before and after Seoul 1339 merged to 119. We compared the Seoul 1339 call response data in 2008 with Seoul and Busan 119 call response data between 2014 and 2016. We analyzed the changes in the trend and quality of data obtained, as well as the quality of service provided by each center before and after this reallocation, by comparing the data each obtained through telephone counselling. Results: The data was collected for a total of 2260 toxin exposure related calls made to Seoul 1339 in 2009, and 1657 calls to 119 in Seoul and Busan between 2014 and 2016. Significant difference was observed for age, sex, and reason for exposure to toxic substance between the two groups. Conclusion: After the integration of 1339 with 119, 119 focused on role of field dispatch and hospital transfer, lacking the consulting on drug poisoning. Moreover, data on exposure to toxic substances at the pre-hospital stage indicate that drug information and counseling are missing or unknown. In addition, first aid or follow-up instructions are not provided. Thus, systematic approach and management are required.

다단계 수압파쇄균열 전파 모델링 연구 (Modeling of Multi-Stage Hydraulic Fracture Propagation)

  • 장영호;성원모
    • 한국가스학회지
    • /
    • 제19권5호
    • /
    • pp.13-19
    • /
    • 2015
  • 본 연구에서는 보다 현실적인 파쇄균열 전파를 묘사하기 위해 수압파쇄균열 전파 모델을 개발하였다. 이 모델에서는 두 가지 균열 전파 기준을 적용하였다. 첫 번째는 균열의 발생각을 결정하기 위한 최대 접선응력 기준과 두 번째는 파쇄균열의 자연균열 통과 여부 기준이다. 본 모델의 검증 결과, 수압파쇄균열이 자연균열을 통과하는 양상이 실험값과 동일함을 확인하였다. 균열의 전파에 직접적인 영향을 미치는 요소인 최대수평응력 방향, 균열면의 마찰계수, 자연균열의 방향성에 대한 민감도 분석 결과, 이론적 기준에 적합하게 균열의 전파 방향과 통과 여부가 결정되는 것으로 나타났다. 기존의 수직 판형 균열 전파 모델과 본 모델을 비교하여 균열의 연결성과 유정 자극부피 측면에서 차이가 있음을 확인하였다.

복공진 인버터를 적용한 고역률 메탈핼라이드 램프용 전자식 안정기에 관한 연구 (A Study on High Power Factor Electronic Ballast for Metal Halide Discharge Lamp Using a Double Resonant Inverter)

  • 박재욱;서철식;남승식;김해준;원재선;김동희
    • 전력전자학회논문지
    • /
    • 제10권4호
    • /
    • pp.313-322
    • /
    • 2005
  • 본 논문은 복공진 인버터를 적용한 250[W] 메탈핼라이드램프를 구동하기 위한 고역률 전자식 안정기를 설계하고 구현하였다. 제안된 전자식 안정기는 역률 개선 회로기능을 갖는 부스트 능동 PFC 회로와 하프 브리지 복공진형 인버터로 구분된 2개의 전력처리단으로 구성되어 있다. 회로 기본동작원리 및 회로 해석은 무차원화 파라미터를 도입하여 범용성을 부여하여 도식적으로 나타내었다. 음향공명을 제거하기 위해 타이머 IC와 구동 IC로 구성된 간단한 주파수 제어기를 구현하였다. 실험을 통해 복공진 인버터를 적용한 고역률 메탈핼라이드램프용 전자식 안정기가 안정적으로 동작함을 확인하였다