• 식물조직배양학회지
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• 제27권4호
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• pp.259-268
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• 2000

Senescence is a sequence of biochemical and physiological events that lead to death of a cell, organ, or whole organism. Senescence is now clearly regarded as a genetically determined and evolutionarilly acquired developmental process comprising the final stage of development. However, in spite of the biological and practical importance, genetic mechanism of senescence has been very limited. Through forward and reverse genetic approaches, we are trying to reveal the molecular and genetic mechanism of senescence in plants, employing leaf organs of Arabidopsis as a model system. Using forward genetic approach, we have initially isolated several delayed senescence mutants either from T-DNA insertional lines or chemical-mutagenized lines. In the case of ore 4 and ore 9 mutants, the mutated genes were identified. The recent progress on characterization of mutants and identification of the mutated genes will be reported. We are also screening mutations from other various sources of mutant pools, such as activation tagging lines and promoter trap lines. Two dominant senescence-delayed mutants were isolated from the activation tagging pool. Cloning of the genes responsible for this phenotype is in progress. For reverse genetic approach, the genes that induced during leaf senescence were first isolated by differential screening method. We are currently using PCR-based suppression subtractive hybridization, designed to enrich a cDNA library for rare differentially expressed transcripts. Using this method, we have identified over 35 new sequences that are upregulated at leaf senescence stage. We are investigating the function of these novel genes by systemically generating antisense lines.

• JSTS:Journal of Semiconductor Technology and Science
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• 제5권2호
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• pp.89-101
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• 2005

Research on highly abstracted system modeling and simulation has received a great deal of attention as of the concept of platform based design is becoming ubiquitous. From a practical design point of view, such modeling and simulation must consider the following: (i) fast simulation speed and cycle accuracy, (ii) early availability for early stage software development, (iii) inter-operability with external tools for software development, and (iv) reusability of the models. Unfortunately, however, all of the previous works only partially addresses the requirements, due to the inherent conflicts among the requirements. The objective of this study is to develop a new system design methodology to effectively address the requirements mentioned above. We propose a new transaction-level system modeling methodology, called ViP (Virtual Platform). We propose a two-step approach in the ViP method. In phase 1, we create a ViP for early stage software development (before RTL freeze). The ViP created in this step provides high speed simulation, lower cycle accuracy with only minor modeling effort.(satisfying (ii)). In phase 2, we refine the ViP to increase the cycle accuracy for system performance analysis and software optimization (satisfying (i)). We also propose a systematic ViP modeling flow and unified interface scheme based on utilities developed for maximizing reusability and productivity (satisfying (ii) and (iv)) and finally, we demonstrate VChannel, a generic scheme to provide a connection between the ViP and the host-resident application software (satisfying (iii)). ViP had been applied to several System-on-a-chip (SoC) designs including mobile applications, enabling engineers to improve performance while reducing the software development time by 30% compared to traditional methods.

• 국제지역연구
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• 제15권3호
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• pp.307-324
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• 2011

세계 각국은 침체에 빠진 경제를 재건해야 하는 동시에 지구온난화로 촉발된 환경문제까지 고려해야 하는 상황에 놓였다. 이 같은 상황에서 기존의 다양한 선행 연구는 생산증가와 환경보호를 동시에 수용하는 녹색 생산성을 정확하게 분석하지 못한다는 문제를 가지고 있다. 이러한 한계를 극복하기 위해 본 논문에서는 녹색 생산성이라는 새로운 개념을 제시하고 그 도출 방법을 체계화하였다. 뿐만 아니라 녹색생산성에 대한 영향을 미치는 결정적 정책변수를 파악하기 위해 1단계 DEA 분석을 통한 생산성 지수를 비교하고, 이에 기초하여 2단계 붓트렙 회귀분석을 실시하여 그 결정요인을 분석하였다. 1단계 실증분석의 결과, 미국, 일본, 유럽연합에 비해 한국의 녹색 생산성 지표는 크게 미흡한 것으로 나타났으며, 그 원인을 찾기 위한 2단계의 회귀분석 결과, 국가총생산, 에너지집약도, 탄소집약도, 자본집약도, 노동집약도의 변수가 정부의 환경오염 감축 노력보다 중요한 것으로 나타났고, 이를 위해 요소투입형 생산구조에서 요소의 질적 고도화가 필요함을 지적하였다.

• Nuclear Engineering and Technology
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• 제54권9호
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• pp.3516-3525
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• 2022

The high capture cross-section (𝜎_c) of Gadolinium (Gd-155 and Gd-157) causes reactivity penalty and swing at the initial stage of fuel burnup in Pressurized Water Reactor (PWR). The present study is concerned with the feasibility of the combination of mixed burnable poison with both low and high 𝜎_c as an approach to minimize these effects. Two considered reference designs are fuel assemblies with 24 IBA rods of Gd₂O₃ and Er₂O₃ respectively. Models comprise nuclear fuel with a homogeneous mixture of Er₂O₃, AmO₂, SmO₂, and HfO₂ with Gd₂O₃ as well as the coating of PaO₂ and ZrB₂ on the Gd₂O₃ pellet's outer surface. The infinite multiplication factor was determined and reactivity was calculated considering 3% neutron leakage rate. All models except Er₂O₃ and SmO₂ showed expected results namely higher values of these parameters than the reference design of Gd₂O₃ at the early burnup period. The highest value was found for the model of PaO₂ and Gd₂O₃ followed by ZrB₂ and HfO₂. The cycle burnup, discharge burnup, and cycle length for three batch refueling were calculated using Linear Reactivity Model (LRM). The pin power distribution, energy-dependent neutron flux and Fuel Temperature Coefficient (FTC) were also studied. An optimization of model 1 was carried out to investigate effects of different isotopic compositions of Gd₂O₃ and absorber coating thickness.

• Journal of Information Processing Systems
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• 제9권2호
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• pp.301-314
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• 2013

In a parallel processing system, Multi-stage Interconnection Networks (MINs) play a vital role in making the network reliable and cost effective. The MIN is an important piece of architecture for a multiprocessor system, and it has a good impact in the field of communication. Optical Multi-stage Interconnection Networks (OMINs) are the advanced version of MINs. The main problem with OMINs is crosstalk. This paper, presents the (1) Destination Based Modified Omega Network (DBMON) and the (2) Destination Based Scheduling Algorithm (DBSA). DBSA does the scheduling for a source and their corresponding destination address for messages transmission and these scheduled addresses are passed through DBMON. Furthermore, the performance of DBMON is compared with the Crosstalk-Free Modified Omega Network (CFMON). CFMON also minimizes the crosstalk in a minimum number of passes. Results show that DBMON is better than CFMON in terms of the average number of passes and execution time. DBSA can transmit all the messages in only two passes from any source to any destination, through DBMON and without crosstalk. This network is the modified form of the original omega network. Crosstalk minimization is the main objective of the proposed algorithm and proposed network.

• 한국가구학회지
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• 제23권2호
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• pp.144-151
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• 2012

The main objective of this study is to explore methods to generate and develop its design concept of the discord generated due to this by deeply considering the existing design concept of a new town or site planning. In particular, in case when designers participate in a process of planning new town, this study aims to reveal methods generating design strategy and basic ideas for designing street furniture through cases study of projects by understanding and analyzing concept of overall space planning and by developing direction for deployment of specific designs. First, further concepts of the space planning, which decides overall flow of visual design concept of street furniture, is extracted through analyses of basic concepts of space design with doing Focused Group Interview among designers and planners. Then, by applying 3V Design Process, alternatives of the concept generation are suggested through methods of storytelling and visual language under the two approach methods of verbalization stage and visualization stage. Also its process were explored through suggestion of designs by developing each idea of the respective concepts into specific design vocabulary.

• 한국지하수토양환경학회지:지하수토양환경
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• 제20권7호
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• pp.13-22
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• 2015

In this study, we have developed the performance evaluation model for the optimal soil remediation technology selection. Performance evaluation model is composed in the evaluation of two steps. In the first stage, the candidate technologies are derived according to the conditions of drilling, type and concentration of pollutants, and the saturated/unsaturated of target site. In the second stage, each individual candidate technology is evaluated by performance evaluation model. The performance evaluation model has 5 groups of evaluation items and 12 evaluation items which have their own evaluation index and their own weights through the AHP approach surveying 40 experts. From the case study of actual design cases, the applicability of the performance evaluation model was confirmed.

• 한국산학기술학회논문지
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• 제11권4호
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• pp.1171-1177
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• 2010

본 논문은 직교배열실험에 기반한 'Pick-the-Winner'법과 설계공간축소법에 기초하여 사출성형 제품의 휨을 잡음(noise)의 존재 하에서도 최소화할 수 있는 강건설계 절차를 제시한다. 강건설계는 현실적 요구를 반영하여 두 단계의 이원적 최적화 과정, 즉 제품 형상에 대한 강건설계와 공정조건에 대한 강건설계로 이루어진다. 제안한 강건설계 절차를 사각형 박막 제품의 설계에 적용한 결과, 본 강건설계법이 현실적 효용성이 있음을 확인하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.823-827
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• 2016

Determination of the colorectal cancer stage is possible only after surgery based on pathology results. However, sometimes this may prove impossible. The aim of the present study was to determine colorectal cancer stage using three clustering methods based on preoperative clinical findings. All patients referred to the Colorectal Research Center of Shiraz University of Medical Sciences for colorectal cancer surgery during 2006 to 2014 were enrolled in the study. Accordingly, 117 cases participated. Three clustering algorithms were utilized including k-means, hierarchical and fuzzy c-means clustering methods. External validity measures such as sensitivity, specificity and accuracy were used for evaluation of the methods. The results revealed maximum accuracy and sensitivity values for the hierarchical and a maximum specificity value for the fuzzy c-means clustering methods. Furthermore, according to the internal validity measures for the present data set, the optimal number of clusters was two (silhouette coefficient) and the fuzzy c-means algorithm was more appropriate than the k-means clustering approach by increasing the number of clusters.

• 대한기계학회논문집A
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• 제21권10호
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• pp.1656-1665
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• 1997

The intake noise, a major source of vehicle noises, has rapidly become a noticeable, and has been studied to reduce the level. Traditionally, the intake system has been developed through a experiment, namely, the trial and error process. This approach requires very high cost and long time consuming to develop the systm. Recently, FEM and BEM are becoming useful in analysis of the intake system, and the results of analysis are very valid. But because this techniques also require high cost and long analysis time, this technique is generally not practical tool at the early stage of the development. In this study, the software was developed to predict and analyze the acoustic characteristics of the intake system. It was based on the Transfer Matrix Method and operated to analyze a simplified intake system in a personal computer. It can be used early in the design stage of development of the intake system. This study presented a improvement to reduce the level of the intake noise, which modified the specification of the intake system. And the improvement were verified by NIT/SYSNOISE, FE analysis commercial software, and testing a prototype.