• Journal of Microbiology and Biotechnology
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• 제8권2호
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• pp.182-184
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• 1998

PCR was used for quantitative counting of Bifidobacterium spp. in a sample mixed with Lactobacillus acidophilus using two primer sets; one set for universal priming and the other set for Bifidobacterium specific priming. DNA products from two independent PCRs with DNA extracted from the mixed sample were found to be easily distinguishable from each other by agarose gel electrophoresis. The concentrations of PCR products correlated with the total number of bacteria and with the number of Bifidobacterium spp. present in the sample.

• Journal of applied mathematics & informatics
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• 제5권1호
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• pp.263-268
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• 1998

This paper proposes the two-sample comparison us-ing sign test based on ranked-set sample(RSS). We investigate the asymptotic properties of the proposed test statistic and compare the asymptotic relative efficiencies of the proposed test statistic with re-spect to Mann-Whitney-Wilcoxon test statistic based on RSS and Mann-Whitney-Wilcoxon test statistic based on the simple random sample(SRS).

• Journal of Preventive Medicine and Public Health
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• 제40권2호
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• pp.114-121
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• 2007

Power and sample size estimation is one of the crucially important steps in planning a genetic association study to achieve the ultimate goal, identifying candidate genes for disease susceptibility, by designing the study in such a way as to maximize the success possibility and minimize the cost. Here we review the optimal two-stage genotyping designs for genomewide association studies recently investigated by Wang et al(2006). We review two mathematical frameworks most commonly used to compute power in genetic association studies prior to the main study: Monte-Carlo and non-central chi-square estimates. Statistical powers are computed by these two approaches for case-control genotypic tests under one-stage direct association study design. Then we discuss how the linkage-disequilibrium strength affects power and sample size, and how to use empirically-derived distributions of important parameters for power calculations. We provide useful information on publicly available softwares developed to compute power and sample size for various study designs.

• 응용통계연구
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• 제15권2호
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• pp.297-310
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• 2002

Liang과 Zeger는 이산형 혹은 연속형 반복측정자료를 분석하기 위한 일반화 추정방정식 (GEE)을 제안하였다 GEE모형은 범주형 반복측정자료의 모형으로 확장될 수 있으며, 이 GEE추정량은 대표본인 경우 다변량 정규분포를 따른다. 그러나 GEE는 대표본근사이론에 기초한다. 본 논문에서는 소표본인 경우 반복 측정된 순서자료에 대한 GEE추정량의 성질을 연구한다. 우리는 두가지 방법을 사용하여 두그룹의 반복 측정된 순서자료를 생성하며 모의실험을 통하여 소표본인 경우 여러 개 범주를 갖는 순서반응 자료에 대하여 GEE추정량의 1종 오류율, 검정력, 상대효율, 두 그룹의 표본크기가 다를 경우 효과, 그리고 분산 추정량의 성질등을 연구한다.

• 재무관리연구
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• 제26권2호
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• pp.181-201
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• 2009

This study is on the forecasting performance analysis of range volatility estimators(Parkinson, Garman and Klass, and Rogers and Satchell) relative to historical one using two-scale realized volatility estimator as a benchmark. American sub-prime mortgage loan shock to Korean stock markets happened in sample period(January 2, 2006~March 10, 2008), so the structural change somewhere within this period can make a huge influence on the results. Therefore sample was divided into two sub-samples by May 30, 2007 according to Zivot and Andrews unit root test results. As expected, the second sub-sample was much more volatile than the first sub-sample. As a result of forecasting performance analysis, Rogers and Satchell volatility estimator showed the best forecasting performance in the full sample and relatively better forecasting performance than other estimators in sub-samples. Range volatility estimators showed better forecasting performance than historical volatility estimator during the period before the outbreak of structural change(the first sub-sample). On the contrary, the forecasting performance of range volatility estimators couldn't beat that of historical volatility estimator during the period after this event(the second sub-sample). The main culprit of this result seems to be the increment of range volatility caused by that of intraday volatility after structural change.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 춘계 학술발표회 초청강연 및 논문집
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• pp.1004-1011
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• 2008

In this study, obtained large block sample and piston sample of marine clay in korea were performed unconfined compression and consolidation test. Soil properties of two type samples such as failure strain, between two parameter's ratio($E_{50}$ and $q_u$), and volumetric strain were used to evaluate sample disturbance. The result, large block samples show a low disturbance than piston samples. Therefore, we suggest new sample disturbance evaluated method through the relation of OCR and volumaric strain at shallow of marine clay in Korea and suggest new sample disturbance classified method by subdivided grade for failure strain of unconfined compression test.

• 한국통신학회논문지
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• 제16권5호
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• pp.445-448
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• 1991

두 표본을 쓸 수 있을 때 순위 통계량을 써서 가산성 잡음이 섞여 있는 확률 신호를 검파하는 국소 최적 순위 검파기를 얻었다. 이 검파기는 확률 신호를 검파하는 국소 최적 검파기나 한 표본을 쓰는 국소 최적 순위 검파기와 비슷한 열개를 가지며, 알려진 신호를 검파하는 두 표본 국소 최적 순위 검파기를 일반화한 꼴을 가진다는 것을 보였다. 뿐만 아니라, 입력이 여러 개 있을 때에 확률 신호를 국소 최적 순위 검파하는 문제도 간략히 살펴보았다.

• Communications for Statistical Applications and Methods
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• 제27권4호
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• pp.397-412
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• 2020

In this paper, a notion of data depth is used to propose nonparametric multivariate two sample tests for difference between scale parameters. Data depth can be used to measure the centrality or outlying-ness of the multivariate data point relative to data cloud. A difference in the scale parameters indicates the difference in the depth values of a multivariate data point. By observing this fact on a depth vs depth plot (DD-plot), we propose nonparametric multivariate two sample tests for scale parameters of multivariate distributions. The p-values of these proposed tests are obtained by using Fisher's permutation approach. The power performance of these proposed tests has been reported for few symmetric and skewed multivariate distributions with the existing tests. Illustration with real-life data is also provided.

• 응용통계연구
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• 제13권2호
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• pp.575-590
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• 2000

Greenberg et al.(1969)은 무관질문모형에서 무관한 속성이 미지인 경우 두 개의 독립표본을 이용하여 민감한 속성에 대한 모비율을 추정해 내는 이표본 무관질문모형을 제안하였다. 본 논문에서는 Mangat-Singh(1990)의 모형을 개선한 형태의 김종호 외 2인(1992)이 제안한 2단계 무관질문모형과 이기성과 홍기학(1998)이 제안한 개선된 무관질 문모형을 무관한 속성이 미지일 때 두 개의 독립표본을 이용하는 2단계 이표본 무관질 문모형과 개선된 이표본 무관질문모형으로 확장하였다. 그리고, Greenberg et al. 의 모형과 2단계 이표본 무관질문모형, 그리고 개선되 이표본 무관질문모형과의 효율성을 비교 하였다.

• Bulletin of the Korean Chemical Society
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• 제32권12호
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• pp.4291-4296
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• 2011

Gravitational SPLITT fractionation (GSF) provides separation of colloidal particles into two subpopulations in a preparative scale. Conventionally, GSF is carried out in a thin rectangular channel having two inlets and two outlets at the top and bottom of the channel, respectively. And the channel is equipped with two flow-splitters, one between the top and bottom inlets and another between the top and bottom outlets. A large scale splitter-less GSF system had been developed, which was designed to operate in the full feed depletion (FFD) mode. In the FFD mode, there is only one inlet through which the sample is fed, thus preventing the sample dilution. In this study, the effect of the sample-loading (in the unit of g/hr) on the fractionation efficiency (FE, number% of particles in a GSF fraction that have the sizes expected by theory) of the new large scale splitter-less FFD-GSF system was investigated. The system was tested in the sample-loading range of 3.0-12.0 g/hr with polyurethane latex beads (PU) and sea-sediment. It was found that there is an optimum range in the sample-loading for a FFD-GSF separation. It was also found that there is a general tendency of FE decreasing as the concentration of the sample suspension increases.