• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.83-83
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• 2013

To date, various nanobiotechnologicalapproaches for biosensors and drug development have been explosively studied. Despite of successful demonstrations, the new technologies hardly enjoyed routine applications in practical nanobiomedicine. Here, researchers trained at the interface of basic sciences and engineering are expected to play critical roles. In this tutorial, I will introduce recent studies which harness graphene derivatives for developing bioanalytical platforms to quantitatively analyze various enzyme activities and biomarkers. The systems rely on attractive interaction between graphene oxide and nucleic acids or phospholipids. Recently, one of the graphene-based bioassay system was applied to anti-viral drug screening and potent hit compounds were identified to treat hepatitis C. This study clearly shows that a new nanobio-technology can be routinely implemented in drug discovery, providing many advantages over conventional methods.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1996.04a
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• pp.30-35
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• 1996

Penalty technique perhaps is the most common technique used in the genetic algorithms for constrained optimization problems. In recent years, several techniques have been proposed in the area of evolutionary computation. However, there is no general guideline on designing penalty function and constructing an efficient penalty function is quite problem-dependent. The purpose of the paper is to give a tutorial survey of recent works on penalty techniques used in genetic algorithms and to give a better classification on exisitng works, which may be helpful for revealing the intrinsic relationship among them and for providing some hints for further studies on penalty techniques.

• Journal of Astronomy and Space Sciences
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• v.27 no.2
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• pp.145-152
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• 2010

In this paper, we developed a local oscillator (LO) system of millimeter wave band receiver for radio astronomy observation. We measured the phase and amplitude drift stability of this LO system. The voltage control oscillator (VCO) of this LO system use the 3 mm band Gunn oscillator. We developed the digital phase locked loop (DPLL) module for the LO PLL function that can be computer-controlled. To verify the performance, we measured the output frequency/power and the phase/amplitude drift stability of the developed module and the commercial PLL module, respectively. We show the good performance of the LO system based on the developed PLL module from the measured data analysis. The test results and discussion will be useful tutorial reference to design the LO system for very long baseline interferometry (VLBI) receiver and single dish radio astronomy receiver at the 3 mm frequency band.

• Journal of Communications and Networks
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• v.5 no.2
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• pp.96-103
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• 2003

Asymptotic theorems are very commonly used in probability. For systems whose performance depends on a set of n random parameters, asymptotic analyses for n${\to}{\infty}$ are often used to simplify calculations and obtain results yielding useful hints at the behavior of the system for finite n. These asymptotic analyses are especially useful whenever the convergence to the asymptotic results is so fast that even for moderate n they yield results close to the true values. This tutorial paper illustrates this principle by applying it to capacity calculations of multiple-antenna systems.

• Bulletin of the Korean Chemical Society
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• v.35 no.11
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• pp.3143-3155
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• 2014

This tutorial review provides a general account of the electrochemical behavior of quinones and their various applications. Quinone electrochemistry has been investigated for a long time due to its complexity. A simple point of view is developed that considers the relative stability of the reduced quinone species and the values of the first and second reduction potentials. The 9-membered square scheme in buffered aqueous solutions is explained and semiquinone radical stability is discussed in this context. Quinone redox reaction has also been employed in various studies. Diverse examples are presented under three broad categories defined by the roles of quinone: molecular tool for physical chemistry, versatile electron mediator, and charge storage for energy conversion devices.

• Journal of Institute of Control, Robotics and Systems
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• v.8 no.5
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• pp.413-417
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• 2002

The Internet technology has been recognized not only as a tool far communication in the 21st century but also as an environment for enabling changes in the paradigm of teaching and learning. This paper describes a web-based system development for chemical engineering education. Simulation and visualization of dynamic systems in the environment of a standard web-browser is made possible by extending its capabilities. ActiveX control is used to simulate the system tool far online representation of Virtual Lab. System that is developed using visual basic. The courseware is classified into tutorial, exercises, and virtual experiments.

• Proceedings of the Korean Association of Geographic Inforamtion Studies Conference
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• 2003.04a
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• pp.15-20
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• 2003

한국항공우주연구원은 공공기술연구회 산하 한국지질자원연구원, 한국해양연구원, 한국건설기술연구원과 협력하여 2002년 4월 17일에 본격적인 원격탐사 연구 및 공공지원 업무의 주축을 담당하게 될 공공원격탐사센터를 설립하였다. 별도의 독립조직이 아니라 원격탐사위성인 아리랑위성을 개발, 운영하고 있는 한국항공우주연구원을 중심으로, 한국해양연구원, 한국지질자원연구원, 한국건설기술연구원등 관련기관이 해양분야, 지상분야, 건설분야 등 각 전문분야 별로 협동연구 체계를 구축, 실질적인 국가원격탐사센터 역할을 수행할 것이다. 이와 같이 설립된 공공원격탐사센터에 대한 홍보, 위성자료의 공공활용 지원 및 원격탐사 Tutorial 등을 사용자들이 쉽게 접속하여 이용할 수 있도록 공공원격탐사센터 홈페이지를 구축하여 Open 하게 되었다. 공공원격탐사센터 본부인 한국항공우주연구원을 비롯하여 전문센터별로도 홈페이지를 구축하여 서로 연결되도록 하였다. 2003년도에는 이와 같이 open 된 홈페이지에 위성자료 통합 DB를 구축하여 서비스할 예정이다.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.8 no.5
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• pp.167-172
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• 2008

The purpose of the project was intended to show an application method of RTOS to PICmicro with limited resources with several tasks controlling the peripheral devices. The application runs on the designed PIC16F87x evaluation board with a bootloader burned so the application program can be easily downloaded using the serial communication without using the ROM writer. Thus, it would also be a good example to use for instructional or tutorial purposes for PICmicro education. The demo shows a useful examples who wish to use the real time operation system in their own projects.

• Child Health Nursing Research
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• v.12 no.2
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• pp.160-169
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• 2006

Purpose: This study was to explore the child's health and learning needs of mother of children with leukemia in a children school of a hospital and to describe the basic material for intervention program development. Methods: Participants in this study was 7 mother of children with leukemia. Data collection consisted of in-depth focus group interviews done from April 21 to 30 in 2005. Results: 3 categories emerged from 9 theme clusters. The categories was 'tutorial service', 'emotional service' and 'disease control'. Conclusion: The results of this study show that pediatric nurses need to pay attention to the learning needs of mother and children in the children school of hospital and develop the program to support the children with leukemia and chronic disease.

• Interdisciplinary Bio Central
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• v.2 no.4
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• pp.9.1-9.5
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• 2010

Many neurodegenerative diseases, such as Alzheimer's and Parkinson's disease, are devastating disorders that affect millions of people worldwide. However, the number of therapeutic options remains severely limited with only symptomatic management therapies available. With the better understanding of the pathogenesis of neurodegenerative diseases, discovery efforts for disease-modifying drugs have increased dramatically in recent years. However, the process of translating basic science discovery into novel therapies is still lagging behind for various reasons. The task of finding new effective drugs targeting central nervous system (CNS) has unique challenges due to blood-brain barrier (BBB). Furthermore, the relatively slow progress of neurodegenerative disorders create another level of difficulty, as clinical trials must be carried out for an extended period of time. This review is intended to provide molecular and cell biologists with working knowledge and resources on CNS drug discovery and development.