• 제목/요약/키워드: Tumor excision

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Upper eyelid Merkel cell carcinoma treated with neoadjuvant chemotherapy and surgical excision

  • Toto, Vito;Colapietra, Alfredo;Alessandri-Bonetti, Mario;Vincenzi, Bruno;Devirgiliis, Valeria;Panasiti, Vincenzo;Persichetti, Paolo
    • Archives of Craniofacial Surgery
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    • v.20 no.2
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    • pp.121-125
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    • 2019
  • Merkel cell carcinoma is a rare cutaneous carcinoma, featured by an aggressive clinical course and a mortality rate of 28% at 2 years. A 71-year-old female was affected by a 4.1-cm-wide locally advanced Merkel cell carcinoma of the upper eyelid, previously misdiagnosed as chalazion, with involvement of the extraocular muscles. Although the tumor showed a macroscopic spontaneous regression in size after the incisional biopsy, the mass was treated with neoadjuvant chemotherapy and surgical excision. Good functional and aesthetic result with preservation of the eyeball and absence of tumor recurrence were achieved at 3-year follow-up. In our experience, the combination of the inflammatory cascade due to the incisional biopsy and neoadjuvant chemotherapy led to the regression of a locally advanced large Merkel cell carcinoma of the eyelid.

A Case of Follicular Dendritic Cell Sarcoma in Submandibular Region (악하부에 발생한 여포성 수지상세포 육종 1예)

  • Jae Ho Yoo;Dong Won Lee;Jeong Kyu Kim
    • Korean Journal of Head & Neck Oncology
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    • v.39 no.2
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    • pp.41-44
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    • 2023
  • Follicular dendritic cell sarcoma (FDCS) is rare lymphoid sarcoma occurs anywhere in body, mostly in lymph nodes. Sixty-two-year-old man presented left submandibular gland region mass for 5 months. Mass excision with submandibular gland resection was performed. Histopathology showed proliferation of spindle and ovoid cells with storiform arrangement which were positive for CD21, CD23, Vimentin, Ki-67, suggested FDCS in submandibular gland region lymph node. Tumor size was 3cm with no involvement of resection margin, nor cellular atypia and necrosis, so regular follow up was performed. After 4 years, new enhancing mass in left submandibular area was found. Wide excision of mass with neck dissection on left level I-III was performed. Histopathology confirmed recurrence of FDCS. The patient underwent radiation therapy from left mandible to hyoid area. After 2 years, new nodule was found in left lung upper lobe, and wedge resection confirmed metastasis of FDCS. The patient is on adjuvant chemotherapy.

Osteomalacia and Hypophosphatemia Caused by Phosphaturic Mesenchymal Tumor Mixed Connective Tissue Variant (PMTMCT) -A Case Report- (골연화증과 저인산혈증을 유발한 인산뇨성 간엽성 종양 -증례 보고-)

  • Jeong, Jae-Yun;Kim, June-Hyuk;Lee, Sang-Hoon;Kim, Han-Soo
    • The Journal of the Korean bone and joint tumor society
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    • v.10 no.2
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    • pp.124-129
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    • 2004
  • The phosphaturic mesenchymal tumor mixed connective tissue variant (PMTMCT) is an extremely rare disease, and is frequently associated with oncogenic osteomalacia showing an paraneoplastic syndrome, which is characterized by phosphaturia, hypophosphatemia, normocalcemia and decreased levels of 1,25-dihydroxyvitamin D3 associated with a tumor. We experienced a 45-year-old female who had a soft tissue tumor on her right buttock causing oncogenic osteomalacia, which was satisfactorily treated by surgical excision of the mass.

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Lumbar Spinal Extradural Angiolipoma : Case Report and Review of the Literature

  • Park, Jin-Hoon;Jeon, Sang-Ryong;Rhim, Seung-Chul;Roh, Sung-Woo
    • Journal of Korean Neurosurgical Society
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    • v.44 no.4
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    • pp.265-267
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    • 2008
  • Angiolipomas in the lumbar spinal region are extremely rare. The present report describes the identification of such a tumor and its removal, and discusses the tumor characteristics and prognosis. A 74-year-old woman was presented with a 5-month history of lower back pain. Severe radiculopathy was experienced in the left leg for 5 days prior to the presentation, and there were no neurological deficits. Magnetic resonance (MR) images showed an approximately 3.5 cm heterogeneously enhanced and elongated mass at the left L5-S1 level. A portion of the mass appeared with high signal intensity on T2-weighted MR images, with low signal intensity on T1-weighted images, and with high signal intensity on T1 fat suppression enhancement images. Resection of the tumor was approached via an L5 and S1 laminectomy. A fibrous sticky yellowish hypervascular tumor was identified. Histological study revealed the tumor as an angiolipoma. Symptoms were relieved after tumor excision, and there were no neurological sequelae. Although extremely rare, lumbar epidural angiolipoma should be considered in the differential diagnosis of lumbar spinal epidural lesions. The prognosis after surgical management of this lesion is favorable.

Giant Cell Tumor Arising from Anterior Arc of the Rib

  • Heo, Woon;Kang, Do Kyun;Min, Ho-Ki;Jun, Hee Jae;Hwang, Youn-Ho
    • Journal of Chest Surgery
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    • v.46 no.5
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    • pp.377-379
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    • 2013
  • A primary giant cell tumor of the rib is very rare. The most common site of a giant cell tumor arising from the rib is the posterior arc. A giant cell tumor arising from the anterior arc of the rib is extremely rare. The treatment of a giant cell tumor of the rib is not well defined. Generally, a complete surgical resection is performed in a patient with a primary giant cell tumor of the rib. We report a case of a giant cell tumor arising from the anterior arc of the rib that was treated with a wide excision and chest wall reconstruction.

Granular Cell Tumor in the Lower Lip : A Case Report (하구순의 과립세포종 증례보고)

  • Hur, Gi-Yeun;Oh, Suk-Joon;Koh, Sung-Hoon;Cha, Jeong-Ho;Min, Kwang-Seon
    • Korean Journal of Head & Neck Oncology
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    • v.25 no.1
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    • pp.33-35
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    • 2009
  • Purpose : Granular cell tumour(GCT) is a rare benign tumour that can arise in anywhere throughout the body. Histopathological diagnosis of malignancy is difficult. We report a case of a granular cell tumor which developed on lower lip. Methods : A 58-year-old male had a palpable mass and whitish plaque in the oral mucosa for three months. Results : Under local anasthesia, the tumor was removed through wide excision including normal skin margin. Immediate reconstruction using local flap was done. Pathologic observation showed nests of polygonal cells with abundant granular, eosinophilic cytoplasm and round nuclei. Immunohistopathologic staining showed positive reaction on S-100 protein Conclusion : The results support the hypothesis that granular cell tumor is derived from Schwann cells. We report here on a case of granular cell tumor of lower lip that was successfully treated with radical resection.

A Case of Recurrent Spindle Cell Epithelial Tumor of Thymus-Like Differentiation (SETTLE) in the Glottis (성문에서 발생한 재발성 흉선상 방추상 상피세포 종양(Spindle Epithelial Tumor with Thymus-Like Differentiation, SETTLE) 1예)

  • Park, Woori;Choi, Nayeon;Chung, Man Ki
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.26 no.2
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    • pp.133-136
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    • 2015
  • Spindle epithelial tumor with thymus-like differentiation (SETTLE) is an extremely rare type of thyroid tumor, with spares reports on its clinical course. SETTLE is derived from branchial pouch or thymic remnants, and classified as a low grade, malignant neoplasm due to its indolent growth and tendency to develop delayed metastasis. Therefore, stringent initial workups and long-term follow-up are required to prevent misdiagnosis. We present a case of recurrent spindle epithelial tumor with thymus-like differentiation (SETTLE) in the glottis of 57 year-old male patient, who had a history of surgical excision for the SETTLE from the thyroid gland 5 years ago. Transoral CO2 laser surgery was performed to remove the glottic tumor and there was no evidence of local recurrence at 11 months postoperatively.

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Application of Mini-abdominoplasty after Conservative Excision of Extensive Cesarean Scar Endometriosis

  • Lee, Eui Tai;Park, Hyun Min;Lee, Dong Geun;Shin, Kyung Jin;Kim, Hak Soon;Sung, Ro Hyun;Ryu, Dong Hee
    • Archives of Plastic Surgery
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    • v.39 no.5
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    • pp.551-555
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    • 2012
  • Endometriosis is defined as the presence of functioning endometrial tissue outside the uterine cavity, and the standard treatment is extensive surgical excision. Cesarean scar endometriosis is a type of cutaneous endometriosis arising on or near a Cesarean section scar. A 44-year-old woman presented with a $9{\times}6$ cm sized dark-brown, stony-hard, irregular, lower abdominal mass of four years duration. The patient had a history of two Cesarean deliveries, 14 and 16 years ago. Suspecting endometriosis, we excised the tumor conservatively rather than extensively to prevent incisional hernia considering the benign nature of the tumor and the low possibility of recurrence because the patient's age was near menopause, along with simultaneous bilateral salpingo-oophorectomy that was performed in this case. On reconstruction, mini-abdominoplasty was adopted to avoid possible wound complications and cosmetic deformities. The patient was satisfied with the cosmetic results, and neither recurrence nor functional problems occurred during the 1-year follow-up period. Plastic surgeons should keep in mind the possibility of cutaneous endometriosis in an abdominal mass of a female of reproductive age with a previous history of pelvic or intra-abdominal surgery. An optimal result from oncological, functional, and cosmetic standpoints can be achieved with conservative excision followed by mini-abdominoplasty of extensive Cesarean scar endometriosis.

Polymorphous low-grade adenocarcinoma on hard palate: case report (구개부에 발생한 다형성 저등급 선암종의 치험례)

  • Shin, Young-Min;Choi, So-Young;Kim, Jin-Wook;Byeon, Ki-Jung;Kim, Chin-Soo
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.37 no.1
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    • pp.72-76
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    • 2011
  • Polymorphous low-grade adenocarcinomas (PLGA) are distinctive salivary gland neoplasms with a propensity to arise from the minor salivary glands. The most frequent location of PLGA is the palate, even though other locations have been described. Previously used terms for PLGA include lobular carcinoma and terminal duct carcinoma. Although the frequency of the tumor is unknown, the recognition of PLGA as an individual tumor has increased with the establishment of specific histopathological criteria characterizing the PLGA. The first choice of treatment is a wide surgical excision including the subjacent bone if necessary. The prognosis is generally good and the recurrence rate ranges from 17% and 22%. Distant metastases is unusual (9%) but occur mainly in the regional lymph nodes. This is a case report of a 67 year old female patient with PLGA who was treated with a wide excision by layers (2 stage) of the lesion including the surrounding bone. We present this case with a review of the relevant literature.

Surgical excision of osteochondroma on mandibular condyle via preauricular approach with zygomatic arch osteotomy

  • Park, Sang-Hoon;An, Jun-Hyeong;Han, Jeong Jun;Jung, Seunggon;Park, Hong-Ju;Oh, Hee-Kyun;Kook, Min-Suk
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.39
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    • pp.32.1-32.5
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    • 2017
  • Background: Osteochondroma is a benign tumor that tends to develop in mandibular condyle and coronoid process in the craniofacial region. If tumor mass has grown from condyle into the infratemporal space with zygomatic arch obstructing the access, there are risks associated with surgical exposure and local resection of these masses. Case presentation: This study reports on a case of osteochondroma on mandibular condylar head where we treated with surgical excision via preauricular approach with 3D analysis. After the local resection, there were no surgical and post-operative complications until 8-month follow-up period. Conclusions: In local excision of osteochondroma, our method is a minimally invasive method. It is a good example of osteochondroma treatment.