• 제목/요약/키워드: Triple-well

검색결과 295건 처리시간 0.032초

Response of Triple Negative Breast Cancer to Neoadjuvant Chemotherapy: Correlation between Ki-67 Expression and Pathological Response

  • Elnemr, Gamal M;El-Rashidy, Ahmed H;Osman, Ahmed H;Issa, Lotfi F;Abbas, Osama A;Al-Zahrani, Abdullah S;El-Seman, Sheriff M;Mohammed, Amrallah A;Hassan, Abdelghani A
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권2호
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    • pp.807-813
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    • 2016
  • Triple-negative breast cancers constitute about 15% of all cases, but despite their higher response to neoadjuvant chemotherapy, the tumors are very aggressive and associated with a poor prognosis as well as a higher risk of early recurrence. This study was retrospectively performed on 101 patients with stage II and III invasive breast cancer who received 6-8 cycles of neo-adjuvant chemotherapy. Out of the total, 23 were in the triple negative breast cancer subgroup. Nuclear Ki-67 expression in both the large cohort group (n=101) and triple negative breast cancer subgroup (n=23) and its relation to the pathological response were evaluated. The purpose of the study was to identify the predictive value of nuclear protein Ki-67 expression among patients with invasive breast cancers, involving the triple negative breast cancer subgroup, treated with neoadjuvant chemotherapy in correlation to the rate of pathological complete response. The proliferation marker Ki-67 expression was highest in the triple negative breast cancer subgroup. No appreciable difference in the rate of Ki-67 expression in triple negative breast cancer subgroup using either a cutoff of 14% or 35%. Triple negative breast cancer subgroup showed lower rates of pathological complete response. Achievement of pathological complete response was significantly correlated with smaller tumor size and higher Ki-67 expression. The majority of triple negative breast cancer cases achieved pathological partial response. The study concluded that Ki-67 is a useful tool to predict chemosensitivity in the setting of neoadjuvant chemotherapy for invasive breast cancer but not for the triple negative breast cancer subgroup.

Resonant Characteristics of Triple-Mode Dielectric Resonators

  • Myung, Jae-Yoon;Yun, Sang-Won;Park, Namshin;Lee, Donyong;Kim, Byungchul;Won, Jeonghee;Na, Inho;Jang, Geonho;Wang, Xu-Guang
    • Journal of electromagnetic engineering and science
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    • 제14권1호
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    • pp.9-14
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    • 2014
  • This paper discusses the resonant characteristics, such as the resonant frequencies and Q factors, as well as tuning methods of the resonant frequency of the triple-mode dielectric resonators, for their possible application to compact bandpass filters for mobile communication systems. The resonators include spheres and cylindrical rods that can be applied to compact bandpass filters. These high Q ceramic resonators can replace the conventional coaxial type resonators, which are large sized and also have relatively low Q values. Both simulated and measured results show that the Q values of the sphere and rod reach 27,000 and 24,000, respectively. Decoupling of degenerate modes is also briefly discussed.

Implementation of AES and Triple-DES cryptography using a PCI-based FPGA board

  • Kwon, Oh-Jun;Seike, Hidenori;Kajisaki, Hirotsugu;Kurokawa, Takakazu
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2002년도 ITC-CSCC -2
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    • pp.940-943
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    • 2002
  • This paper presents hardware implementations of the two representative cryptographic algorithms, Advanced Encryption Standard (Rijndael), and the present American federal standard (Triple DES) using a PCI- based FPGA board named "EBSW-1" This board bases on a FPGA chip (Xilinx Virtex300 XCV300PQ240-4). The implementation results of these two algorithms were tested successfully. AES circuit could proceed an encryption as well as a decryption two times faster than the Triple-DES circuit, while the former circuit used higher rates of CLBs. Besides, if these architectures use pipeline-registers, the processing speed will be increased about 1.5 times than the presented circuits.

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변형된 TE$_{113}$/TM$_{012}$ 삼중모드 도파관 대역통과여파기의 구현 (Implementation of a modified TE$_{113}$/TM$_{012}$ triple-mode waveguide bandpass filter)

  • 정근욱;이재현;박광량;김재명
    • 전자공학회논문지A
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    • 제33A권11호
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    • pp.70-77
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    • 1996
  • In this paper, a modifed TE$_{113}$/TM$_{012}$ triple-mode bandpass filter is implemented by using a modified inter-cavity iris in which the number of slots are reduced upto 50%. In a coventioanl iris two prirs of slot apertures are used to independently couple three resonant modes between two adjacent cavities. However, if transverse magnetic polarizability of a pair of veritcal slot apertures is used to control weak horizontal TE$_{h}$-TE$_{h}$ mode coupling, the width of novel iris slots would substitute for the slot length of the conventional iris, causing to eliminate the horizontal slot apertures. The measured data of two filters, which are the modified filter and ocnventional one, are compared. Experimental result shows that the characteristics of the novel triple-mode filter matches well that of the conventional filter.

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삼중 버퍼링 방법을 이용한 실시간 소나 신호 디스플레이를 위한 FPGA 임베디드 시스템의 구현 (An Implementation of FPGA Embedded System for Real-Time SONAR Signal Display Using the Triple Buffering Method)

  • 김동진;박영석
    • 대한임베디드공학회논문지
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    • 제9권3호
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    • pp.173-182
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    • 2014
  • The CRT monitor display system for SONAR signal that are commonly used in ships or naval vessels uses vector scanning method. Therefore the processing circuits of the system are complex. Also the purchase of parts is difficult as well as high-cost because the production had been shut down. FPGA-based embedded system is flexible to various digital applications because it can be able to simplify processing circuits and to make a easy customized design for end user, and it provides low-cost high-speed performance. In this paper, we describe an implementation of FPGA embedded system for real-time SONAR signal display using the triple buffering method to overcome some weakness of existing CRT system. Our system provides real-time acquisition and display capability of SONAR signal, and removes afterimage effect that is a critical problem of the system proposed in the preceding study.

500MW 동기발전기용 시뮬레이터 탑재형 디지털 삼중화 여자시스템 개발 (Development of the Triple Modular Redundant Excitation System with Simulator for 500MW Synchronous Generator)

  • 류호선;차한주
    • 전기학회논문지
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    • 제63권1호
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    • pp.70-75
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    • 2014
  • TMR(triple modular redundant) digital excitation system with simulator is developed for tuning optimal control parameters during commissioning test and coping with system faults rapidly. A new system which mocks up virtual generator, turbine, grid can simulate as if excitation system is connected to a real generator system by setting four switches. The maintenance crew using the simulator is able to test perfectly the phase controller rectifiers, field breaker, sequence relays as well as TMR controller of the excitation system. Commissioning and performance results about the excitation system with simulator is discussed. The trial product was installed and operated at a 500MW thermal power plant after the commissioning test.

희박연소에서 발생하는 메탄의 농도 상호작용과 삼중화염에 대한 연구 (Concentration Interaction of Premixed and Triple-layer Flames in Lean Burn with Methane Fuel)

  • 오태균;정석호
    • 한국자동차공학회논문집
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    • 제14권6호
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    • pp.171-178
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    • 2006
  • The performance in the practical combustion system including reciprocating engines and gas turbine combustors is being much governed by turbulent reacting flow that is often analyzed by both a laminar flamelets concept and flame interaction. The characteristics of laminar flame interaction have been investigated numerically to provide basic understanding of wrinkled turbulent flames under concentration interaction resulting from inhomogeneity in fuel-air mixing, especially focused on the transition of flame characteristics such as diffusion flame, partially premixed diffusion flame, and triple-layer flame by the variation in the degree of premixedness. The extinction stretch rates to the premixedness have also been obtained in this paper. The boundary defining the regime of the existence of triple-layer flames as functions of both stretch rate and premixedness has been determined which agrees well with previously reported experiment measuring OH radical concentration peaks based on PLIF.

평편족의 치료로 이용한 관절고정술시 스프링인대군 (spring ligament complex)에서 strain의 변화 (The strain of the spring ligament complex at different arthrodesis of the hindfoot for treatment of the flatfoot)

  • 이경태;배준우
    • 대한족부족관절학회지
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    • 제1권1호
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    • pp.38-42
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    • 1997
  • It was well known that arthrodesis of the tarsal joint is an exellent procedure to correct the flatfoot deformity for relieving pain. Recently, concept of the selective tarsal joint fusion instead of the triple fusion was developedto preserve the joint motion. To investigate and compare the effect of the each different tarsal fusion, we measured the strain at the spring ligament, medial roof of the medial longitudianl arch. Five fresh frozen cadevar foot specimens, with distal half of the tibia were utilized. The superomedial portion of the spring ligament complex was dissected from the origin to the insertion. For each specimen, a calibrated open liquid metal strain guage was secured along the length of the superomedial portion. Under the specially devised test rig, measurement of the strain was taken at each test condition from the tare weight 18.2 lb followed by 38.2 lb., 82.2 lb and a maximum loads of 134.6 lb. : 1) unfused condition, 2) isolated subtalar fusion 3) isolated talonavicular fusion 4) combined subtalar and talonavicular fusion 5) triple fusion. Statistics showed that siginificant reduction in strain following the triple fusion, and from the subtalar fusion to triple fusion.

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