• Title/Summary/Keyword: Trial subject

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발해의 복식에 관한 연구(II) -러시아 연해주에서 발견된 청동용을 중심으로- (A Study on the Costume of Balhae Dynasty(II) -Focused on the costume of a bronze state excavated in the Maritime Provinces of Russia-)

  • 김민지
    • 복식
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    • 제22권
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    • pp.97-118
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    • 1994
  • This stud is my second trial to examine the costume of Balhae Dyansty. The subject of this study is the costume of a bronze statue excavated in the Maritime Provinces of Russia. The bronze statue is in the custody of Vladivostok Museum E.V. Shavkunov a Russian archelogist reported it a statue of-ficial of balhae dynasty in the 7-8th century. Judged his report lack of basis I suggest new opinion on sex, age, married or unmarried. social position manufactured time of the statue by comparative study on the costume hair-style and appearance of the statue with around nations' antiquities. hair-style of the statue is basically included in Ssangge and complexed style of Sage Ssangsuhuange, and Guange, Generally, Ssangge is a hair style of children, unmarried women, court ladies, dancing girls, and instrument player (lady)s'. The statue wears round-necked blouse long skirt broad fabric belt at high waist broad sleeve and confront collar coat cloud shaped shawl and risen tip shoes. The figure of statue is de-scribed plump. The statue shows straight sil-houette and high waist typical style of Tang, Uddai, The most characteristic facto is cloud shaped shawl Cloud shaped shawl was originally one of the northern race's shoulder ornaments. From the view of Comparative study the antiquities of NamDang and JunChock are simi-lar to this statue. Besides Tsukanovka river where the statue was excavated is Kraskino ruins of a castle formed single cultural layer of Balhae Dynasty and are relics of the layer of Balhae Dynasty and are relics of the latter period of Balhae Dynasty. Therefore this statue is assumed to have been manufactured at the last years of Balhae Dynasty and to be a figure of unmarried woman not official.

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일반인의 발목관절에 키네시오 테이핑 적용이 고유감각에 미치는 영향 (Effect of Kinesiotaping on The Ankle Proprioception in Normal Subjects)

  • 이석주;이신영;이다슬;오주영;김장곤
    • 대한물리치료과학회지
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    • 제23권1호
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    • pp.18-23
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    • 2016
  • Purpose : The purpose of the present study is to report the effect of proprioception of ankle after kinesiotaping application on ankle. Method : This study has conducted to target 30 average adult subjects with no damage to the ankle joint (16 males and 14 females). The group is divided into experimental group and sham groups in random way. The subjects in the experimental group are applied taping kinesiology on ankle joint. The subjects in the sham group are applied a sham taping on the ankle joint which is not actually affected for real ankle joint problem. Each subjects in both groups has tree trials in plantarflexion, dorsiflexion, inversion, and eversion before and after application of the kinesiotaping or sham taping of the bare footed ankle. The outcome were determined from the difference between the target angle and the trial angle produced by the subject. Results : These results from the experiment shows that the experimental group compared to the difference in kinesiotaping angle values were significantly different from each dorsiflexion (DF), eversion (EV) (p<.05). Otherwise, in the sham group did not produce significant differences in any joint movement. In addition, when we compared between two groups (the experimental and sham groups), it did not show that there was significant differences. Conclusion : First, there is no significant difference between the sham group and kinesiotaping group after proprioceptive tests. Second, even though there is no significant outcome in statistical analysis, there is actual differences in the experiment. This result might be ceiling effect, and if the kinesiotaping were applied to actual ankle injury patients, this taping treatment could be very effective for curing this patient.

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The Effect of Gaze Angle on Muscle Activity and Kinematic Variables during Treadmill Walking

  • Kim, Bo-Suk;Jung, Jae-Hu;Chae, Woen-Sik
    • 한국운동역학회지
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    • 제27권1호
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    • pp.35-43
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    • 2017
  • Objective: The purpose of this study was to determine how gaze angle affects muscle activity and kinematic variables during treadmill walking and to offer scientific information for effective and safe treadmill training environment. Method: Ten male subjects who have no musculoskeletal disorder were recruited. Eight pairs of surface electrodes were attached to the right side of the body to monitor the upper trapezius (UT), rectus abdominis (RA), erector spinae (ES), rectus femoris (RF), bicep femoris (BF), tibialis anterior (TA), medialis gastrocnemius (MG), and lateral gastrocnemius (LG). Two digital camcorders were used to obtain 3-D kinematics of the lower extremity. Each subject walked on a treadmill with a TV monitor at three different heights (eye level; EL, 20% above eye level; AE, 20% below eye level; BE) at speed of 5.0 km/h. For each trial being analyzed, five critical instants and four phases were identified from the video recording. For each dependent variable, one-way ANOVA with repeated measures was used to determine whether there were significant differences among three different conditions (p<.05). When a significant difference was found, post hoc analyses were performed using the contrast procedure. Results: This study found that average and peak IEMG values for EL were generally smaller than the corresponding values for AE and BE but the differences were not statically significant. There were also no significant changes in kinematic variables among three different gaze angles. Conclusion: Based on the results of this study, gaze angle does not affect muscle activity and kinematic variables during treadmill walking. However, it is interesting to note that walking with BE may increase the muscle activity of the trapezius and the lower extremity. Moreover, it may hinder proper dorsiflexion during landing phase. Thus, it seems to reasonable to suggest that inappropriate gaze angle should be avoided in treadmill walking. It is obvious that increased walking speed may cause a significant changes in biomechanical parameters used in this study. It is recommended that future studies be conducted which are similar to the present investigation but using different walking speed.

한방신경정신과 영역의 수면장애 관련 연구현황 (The Current Status about Sleep Disorder in the Journal of Oriental Neuropsychiatry for Evidence Based Medicine)

  • 정진형;하지원;김보경
    • 동의신경정신과학회지
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    • 제23권4호
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    • pp.11-36
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    • 2012
  • Objectives : Sleep Disorders are very common in clinical stages and there are many reports and papers regarding this subject. I try to understand the present state of sleep research in JON (The Journal of Oriental Neuropsychiatry) for the benefits of clinical practice. Methods : We searched and read every article on JON from 1990 to 2012 and selected ones that are related to Sleep Disorder; then analyzed the data to 5 categories, like literature study, case study, Clinical Data-Analysis study, experimental study, and clinical trial. Results : 1. We Found 41 articles relating to sleep disorder in JON form 1999 to 2012, and there were 9 literature studies, 13 case studies, 13 Clinical Data-Analysis studies, 4 experimental studies, and 2 clinical trials. 2. There were Sa-Am Acupuncture Method, Pharmacopuncture, electroacupuncture, and Auricular acupuncture to treat Sleep Disorder. 3. There were many additional treatments like Purgative Therapy, etc. 4. They reported the ordinary sleep pattern of Soeumin and Soyangin, too. 5. In the experimental study, they reported several herbs, herbal prescription on the expression of melatonin receptors, and Punsimgeimgamibang on insomnia, anxiety, emotionality in rats. 6. There were 2 clinical trials, one for Hwabyung-patient with insomnia by acupuncture treatment and another for insomnia in the elderly by ETF-I program. 7. There were 2 case of other sleep disorder (enuresis, sleepwalking) and 2 literature study of dream. Conclusions : In JON regarding sleep disorder, the majority was due to insomnia. Therefore, we also have to expand our sight into other sleep diseases. We need more clinical trials and experimental researches for the construction of EBM Sleep Disorder in Oriental Neuropsychiatry.

Lactobacillus rhamnosus GG Usage in the Prevention of Gastrointestinal and Respiratory Tract Infections in Children with Gastroesophageal Reflux Disease Treated with Proton Pump Inhibitors: A Randomized Double-Blinded Placebo-Controlled Trial

  • Dziechciarz, Piotr;Krenke, Katarzyna;Szajewska, Hania;Horvath, Andrea
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제23권3호
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    • pp.251-258
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    • 2020
  • Purpose: Proton-pump inhibitors (PPIs) are frequently used to treat gastroesophageal reflux disease (GERD) in children, but recent evidence suggests a potential association between PPI treatment and some types of infections. The aim of this study was to assess the effectiveness of Lactobacillus rhamnosus GG (LGG) for the prevention of gastrointestinal and respiratory tract infections in children with GERD treated with PPI (omeprazol). Methods: Children younger than 5 years with GERD were assigned by a computer-generated list to receive LGG (109 colony-forming units) or placebo, twice daily, concomitantly with PPI treatment for 4-6 weeks; they were followed up for 12 weeks after therapy. The primary outcome measures were the percentage of children with a minimum of one episode of respiratory tract infection and the percentage of children with a minimum of one episode of gastrointestinal infection during the study. Results: Of 61 randomized children, 59 patients (LGG n=30; placebo n=29, mean age 11.3 months) were analyzed. There was no significant difference found between the LGG and placebo groups, either for the proportion of children with at least one respiratory tract infection (22/30 vs. 25/29, respectively; relative risk [RR] 0.85, 95% confidence interval [CI] 0.66-1.10) or for the proportion of children with at least one gastrointestinal infection (9/30 vs. 9/29, respectively; RR 0.97, 95% CI 0.45-2.09). Conclusion: LGG was not effective in the prevention of infectious complications in children with GERD receiving PPI. Caution is needed in interpreting these results, as the study was terminated early due to slow subject recruitment.

탄성지반 위에 놓여있는 다지지 보의 동적해석 제2보 : 움직이는 하중에 대한 동적응답 (Dynamic Analysis of the Multi-Span Beam on Elastic Foundation Part two : Dynamic Response for the Moving Loads)

  • 최교준;김용철
    • 대한조선학회논문집
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    • 제28권1호
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    • pp.92-98
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    • 1991
  • 일반적으로 철조 교량과 같은 구조물은 탄성지반위에 놓여있는 다지지보로 모형화 시킬 수 있다. 이러한 구조물 들에 항상 움직이는 하중이 작용하게 된다. 움직이는 하중은 특히 고속일때 구조물에 심한 운동을 일으키며 또한 구조물의 동적응력에 큰 영향을 미치게 된다. 본 연구에서는 탄성지반위에 놓여있는 다지지보의 동적응답을 Galerkin방법과 수치시간적분방법을 사용하여 구하였다. 시도함수로서는 제1보(고유진동수)에서 구한 직교 다항식 함수를 사용하였다. 일반적으로 가정된 해의 첫번째 항만을 사용하여도 정확한 해를 구할 수 있으나, 병진 스프링 상수값이 크거나 회전 스프링이 제일차 모우드의 기울기가 영인 지점에 위치할 경우에는 반드시 고차 모우드를 포함하여 해석해야 정확한 해를 구할 수 있다.

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전라남도 7개 지역에 거주하는 남녀 장수인의 봄과 가을 영양섭취 실태 비교 연구 (Study on Nutrition Intakes of Long-Lived Men and Women Living in Seven Regions in Jellanam-do: Comparisons between Spring and Fall)

  • 전순실;정수영;빙동주;윤은주
    • 동아시아식생활학회지
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    • 제24권6호
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    • pp.723-738
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    • 2014
  • This study examined nutrient intake of long-lived men and women living in Jeollanam-do (Gangjin, Goksung, Gurye, Damyang, Boseong, Suncheon, Jangheung) which is known as representative Korean longevity area. Using the 24 hr recall method, dietary nutrient intake data were collected from 134 subjects (67 for 80~89 years old, 67 for more than 90 years old) in spring and fall 2012. Nutrient for each subject were calculated using CAN-pro. Subjects' daily mean intake levels of macronutrients, vitamins and minerals were higher in fall than in spring. Compared to KDRIs, subjects less than recommend (RNI/AI). East consumed nutrients compared to KDRIs were folate, potassium, calcium, vitamin $B_1$, vitamin $B_2$ and vitamin E. Subjects 232.8~363.1% of recommended intake level for natrium. The nutrient adequacy ratio (NAR) was 0.87 for subjects in their 80s and 0.79 for than 90 years old. The average NAR of all subjects was 0.83. The index of nutritional quality (INQ) exceeded 1 for most nutrients except for Ca (0.87), K (0.77), vitamin $B_1$ (0.84), vitamin $B_2$ (0.70) and folate (0.68). The average INQ was 1.31. This study concluded that even though long-lived men and women living in Jeollanam-do consumed less than RNIs, nutrition consumption quality was relatively fine based on NAR and INQ results.

신약개발을 위한 임상연구간호사의 역할수행과 관련 요인 (Role Performance and Related Factors of Clinical Research Nurses in New Drug Development)

  • 박재은;김신미
    • Journal of Korean Biological Nursing Science
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    • 제22권3호
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    • pp.213-221
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    • 2020
  • Purpose: The purpose of this study was to explore the role performance and related factors of clinical research nurses (CRN) in the process of clinical trials of new drug development. Methods: Study participants were CRN whose affiliation was in non-capital areas and who had been working longer than three months at the time of the data collection. The data collection was conducted with a semi-structured questionnaire development by Hwang & Go, 2011 comprising 16 items of participants' characteristics and 60 items of role performance via in-person and online. Additionally, opinions which would be necessary to establish the CRN role were questioned for the future. A total of 141 questionnaires of 151 questionnaires responses were analyzed using descriptive statistics, t-test, and ANOVA for data analysis as appropriate. Results: The level of overall role performance was above average (5.61±0.90) with the highest in subject care (6.04 ± 0.96) and management and the lowest in self-development (4.39 ± 1.52). The only factor affecting overall role performance was employment status and the only sub-category affected by factors of employment status, and some general characteristics was self-development. Conclusion: From study results, it can be concluded that the CRN seem to perform their proper role. Nonetheless, self-development should be considered as critical aspect for better CRN competency, which is an important aspect toward improving the CRN role performance. Additionally, efforts to improve the level of role performance must be established through stable employment and concrete departmental placement as suggested in this study.

한방분야 적정성 평가 대상 질환 선정을 위한 전문가 Delphi 조사 (Selection of Manageable Diseases for Quality Assessment in Korean Medicine by Delphi Method)

  • 박창현;임형호
    • 한방재활의학과학회지
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    • 제26권3호
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    • pp.129-141
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    • 2016
  • Objectives As awareness of the public about Korean medicine health care and the social demand about improvement for quality of health care service is constantly rising, the quality evaluation of Korean medicine health care service is needed to improve the quality. Through trial of Delphi method, we tried to set the priority in short, medium, long term among the disease which is the subject of quality assessment. Methods Carrying out the delphi survey to 50 experts of korean medicine who were recommended by the 41 member societies of Korean medicine and related organizations, we selected final candidates for quality assessment. It is composed with total 2 rounds, and we investigated the priority in three aspects; the importance of the matter, possibility quality assessment, potential about if there's any chance of improvement. Results By delphi method, we set the priority of quality assessment. Base on the result of the second round, we classified importance of the questions into above average, average, below average, and categorized items as short, medium, long term according on the final priority. We classified of musculoskeletal diseases and diseases of connective tissues and musculoskeletal injury as short term and cerebrovascular disease and disease of nerve system and malignant neoplasm as medium term, disease of digestive organs and diseases, symptoms and abnormal findings in clinical field or inspections which are not categorized as long term. Conclusions We set the subjects of quality assessment by delphi survey by experts, and classified into short, medium, long term. Further research is necessary for execution the Quality Assessment to each of the candidate. Also, we can send feedback to medical institution base on the result of Quality Assessment. then it would be able to induce the improvement in quality of medical institution by itself.

Effect of Korean Red Ginseng extracts on drug-drug interactions

  • Kim, Se-Jin;Choi, Seungmok;Kim, Minsoo;Park, Changmin;Kim, Gyu-Lee;Lee, Si-On;Kang, Wonku;Rhee, Dong-Kwon
    • Journal of Ginseng Research
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    • 제42권3호
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    • pp.370-378
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    • 2018
  • Background: Ginseng has been the subject of many experimental and clinical studies to uncover the diverse biological activities of its constituent compounds. It is a traditional medicine that has been used for its immunostimulatory, antithrombotic, antioxidative, anti-inflammatory, and anticancer effects. Ginseng may interact with concomitant medications and alter metabolism and/or drug transport, which may alter the known efficacy and safety of a drug; thus, the role of ginseng may be controversial when taken with other medications. Methods: We extensively assessed the effects of Korean Red Ginseng (KRG) in rats on the expression of enzymes responsible for drug metabolism [cytochrome p450 (CYP)] and transporters [multiple drug resistance (MDR) and organic anion transporter (OAT)] in vitro and on the pharmacokinetics of two probe drugs, midazolam and fexofenadine, after a 2-wk repeated administration of KRG at different doses. Results: The results showed that 30 mg/kg KRG significantly increased the expression level of CYP3A11 protein in the liver and 100 mg/kg KRG increased both the mRNA and protein expression of OAT1 in the kidney. Additionally, KRG significantly increased the mRNA and protein expression of OAT1, OAT3, and MDR1 in the liver. Although there were no significant changes in the metabolism of midazolam to its major metabolite, 1'-hydroxymidazolam, KRG significantly decreased the systemic exposure of fexofenadine in a dose-dependent manner. Conclusion: Because KRG is used as a health supplement, there is a risk of KRG overdose; thus, a clinical trial of high doses would be useful. The use of KRG in combination with P-glycoprotein substrate drugs should also be carefully monitored.