• 제목/요약/키워드: Trial subject

검색결과 234건 처리시간 0.022초

Low versus standard central venous pressure during laparoscopic liver resection: A systematic review, meta-analysis and trial sequential analysis

  • Mina Stephanos;Christopher M. B. Stewart;Ameen Mahmood;Christopher Brown;Shahin Hajibandeh;Shahab Hajibandeh;Thomas Satyadas
    • 한국간담췌외과학회지
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    • 제28권2호
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    • pp.115-124
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    • 2024
  • To compare the outcomes of low central venous pressure (CVP) to standard CVP during laparoscopic liver resection. The study design was a systematic review following the PRISMA statement standards. The available literature was searched to identify all studies comparing low CVP with standard CVP in patients undergoing laparoscopic liver resection. The outcomes included intraoperative blood loss (primary outcome), need for blood transfusion, mean arterial pressure, operative time, Pringle time, and total complications. Random-effects modelling was applied for analyses. Type I and type II errors were assessed by trial sequential analysis (TSA). A total of 8 studies including 682 patients were included (low CVP group, 342; standard CVP group, 340). Low CVP reduced intraoperative blood loss during laparoscopic liver resection (mean difference [MD], -193.49 mL; 95% confidence interval [CI], -339.86 to -47.12; p = 0.01). However, low CVP did not have any effect on blood transfusion requirement (odds ratio [OR], 0.54; 95% CI, 0.28-1.03; p = 0.06), mean arterial pressure (MD, -1.55 mm Hg; 95% CI, -3.85-0.75; p = 0.19), Pringle time (MD, -0.99 minutes; 95% CI, -5.82-3.84; p = 0.69), operative time (MD, -16.38 minutes; 95% CI, -36.68-3.39; p = 0.11), or total complications (OR, 1.92; 95% CI, 0.97-3.80; p = 0.06). TSA suggested that the meta-analysis for the primary outcome was not subject to type I or II errors. Low CVP may reduce intraoperative blood loss during laparoscopic liver resection (moderate certainty); however, this may not translate into shorter operative time, shorter Pringle time, or less need for blood transfusion. Randomized controlled trials with larger sample sizes will provide more robust evidence.

역도 인상동작 성공 시 최대 바벨무게 예측 (The Forecasting a Maximum Barbell Weight of Snatch Technique in Weightlifting)

  • 하종규;류지선
    • 한국운동역학회지
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    • 제15권3호
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    • pp.143-152
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    • 2005
  • The purpose of this study was to predict the failure or success of the Snatch-lifting trial as a consequence of the stand-up phase simulated in Kane's equation of motion that was effective for the dynamic analysis of multi-segment. This experiment was a case study in which one male athlete (age: 23yrs, height: 154.4cm, weight: 64.5kg) from K University was selected The system of a simulation included a multi-segment system that had one degree of freedom and one generalized coordinate for the shank segment angle. The reference frame was fixed by the Nonlinear Trans formation (NLT) method in order to set up a fixed Cartesian coordinate system in space. A weightlifter lifted a 90kg-barbell that was 75% of subject's maximum lifting capability (120kg). For this study, six cameras (Qualisys Proreflex MCU240s) and two force-plates (Kistler 9286AAs) were used for collecting data. The motion tracks of 11 land markers were attached on the major joints of the body and barbell. The sampling rates of cameras and force-plates were set up 100Hz and 1000Hz, respectively. Data were processed via the Qualisys Track manager (QTM) software. Landmark positions and force-plate amplitudes were simultaneously integrated by Qualisys system The coordinate data were filtered using a fourth-order Butterworth low pass filtering with an estimated optimum cut-off frequency of 9Hz calculated with Andrew & Yu's formula. The input data of the model were derived from experimental data processed in Matlab6.5 and the solution of a model made in Kane's method was solved in Matematica5.0. The conclusions were as follows; 1. The torque motor of the shank with 246Nm from this experiment could lift a maximum barbell weight (158.98kg) which was about 246 times as much as subject's body weight (64.5kg). 2. The torque motor with 166.5 Nm, simulated by angular displacement of the shank matched to the experimental result, could lift a maximum barbell weight (90kg) which was about 1.4 times as much as subject's body weight (64.5kg). 3. Comparing subject's maximum barbell weight (120kg) with a modeling maximum barbell weight (155.51kg) and with an experimental maximum barbell weight (90kg), the differences between these were about +35.7kg and -30kg. These results strongly suggest that if the maximum barbell weight is decided, coaches will be able to provide further knowledge and information to weightlifters for the performance improvement and then prevent injuries from training of weightlifters. It hopes to apply Kane's method to other sports skill as well as weightlifting to simulate its motion in the future study.

자극 습관화가 자동차 경적음의 심리음향 특성에 따른 심리생리적 予분에 미치는 영향 (The influence habituation on psychophysiological differentation of automobile horns with different psychoacoustic characteristics)

  • 민윤기;;이임갑;조문재;손진훈
    • 한국음향학회:학술대회논문집
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    • 한국음향학회 1999년도 학술발표대회 논문집 제18권 1호
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    • pp.263-268
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    • 1999
  • Psychoacoustic characteristics of automobile hems influence subject's subjective evaluation and psychophysiological reactions on the sounds of car horns. However, differentiation of physiological responses to commercially availablenfluence subject's subjective evaluation and psychophysiological reactions on the s horns is a complicated task due to the small contrast in technical features of horns and the influence of habituation. Using 10 college students, comparative analysis of physiological reactivity was carried out in order to identify the effect of habituation on decrement of psychophysiological responsivity, assess the ability to differentiate subjectively most and least preferred/appropriate horns according to physiological manifestations. EEG and autonomic responses to 7 automobile horns were analyzed during 3 blocks of trials (each block was varied in order for presenting stimuli and acoustic parameters of horns). It was shown that electrodermal and cardiovascular responses had different reactivity patterns to repeated stimulation. Skin conductance variables (SCL, SCR) were habituated as a function of trial. Cardiac reactivity (HR, RSA) showed no signs of habituation. In contrast, sensitization was shown in the vascular component of response (pulse volume). The temporal EEG exhibited marked habituation of fast beta band power, while alpha-blocking effect did not habituate during the course of experiment. Differentiation of physiological responses of most and least preferred/appropriate horns was possible in this study. That is, some cardiovascular reactivity variables (HR, RSA, pulse volume, etc.) were differentiated between the least and the most preferred/appropriate horns during the experiment. However, EEG and electrodermal parameters showed significant differences only during first block of trials and were later affected by habituation.

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근육 파라미터 최적화를 통한 발목관절 모멘트 추정 모델 개발 및 평가 (Development and evaluation of estimation model of ankle joint moment from optimization of muscle parameters)

  • 손종상;황성재;이진섭;김영호
    • 대한의용생체공학회:의공학회지
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    • 제31권4호
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    • pp.310-315
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    • 2010
  • Estimation of muscle forces is important in biomechanics, therefore many researchers have tried to build a muscle model. Recently, optimization techniques for adjusting muscle parameters, i.e. EMG-driven model, have been used to estimate muscle forces and predict joint moments. In this study, an EMG-driven model based on the previous studies has been developed and isometric and isokinetic contraction movements were evaluated to validate the developed model. One healthy male participated in this study. The dynamometer tasks were performed for maximum voluntary isometric contractions (MVIC) for ankle dorsi/plantarflexors, isokinetic contraction at both $30^{\circ}/s$ and $60^{\circ}/s$. EMGs were recorded from the tibialis anterior, gastrocnemius medialis, gastrocnemius lateralis and soleus muscles at the sampling rate of 1000 Hz. The MVIC trial was used to customize the EMG-driven model to the specific subject. Once the subject's own model was developed, the model was used to predict the ankle joint moment for the other two dynamic movements. When no optimization was applied to characterize the muscle parameters, weak correlations were observed between the model prediction and the measured joint moment with large RMS error over 100% (r = 0.468 (123%) and r = 0.060 (159%) in $30^{\circ}/s$ and $60^{\circ}/s$ dynamic movements, respectively). However, once optimization was applied to adjust the muscle parameters, the predicted joint moment was highly similar to the measured joint moment with relatively small RMS error below 40% (r = 0.955 (21%) and r = 0.819 (36%) and in $30^{\circ}/s$ and $60^{\circ}/s$ dynamic movements, respectively). We expect that our EMG-driven model will be employed in our future efforts to estimate muscle forces of the elderly.

Human Postural Dynamics in Response to the Horizontal Vibration

  • Shin Young-Kyun;Fard Mohammad A.;Inooka Hikaru;Kim Il-Hwan
    • International Journal of Control, Automation, and Systems
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    • 제4권3호
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    • pp.325-332
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    • 2006
  • The dynamic responses of human standing postural control were investigated when subjects were exposed to long-term horizontal vibration. It was hypothesized that the motion of standing posture complexity mainly occurs in the mid-sagittal plane. The motor-driven support platform was designed as a source of vibration. The AC Servo-controlled motors produced anterior/posterior (AP) motion. The platform acceleration and the trunk angular velocity were used as the input and the output of the system, respectively. A method was proposed to identify the complexity of the standing posture dynamics. That is, during AP platform motion, the subject's knee, hip and neck were tightly constrained by fixing assembly, so the lower extremity, trunk and head of the subject's body were individually immovable. Through this method, it was assumed that the ankle joint rotation mainly contributed to maintaining their body balance. Four subjects took part in this study. During the experiment, the random vibration was generated at a magnitude of $0.44m/s^2$, and the duration of each trial was 40 seconds. Measured data were estimated by the coherence function and the frequency response function for analyzing the dynamic behavior of standing control over a frequency range from 0.2 to 3 Hz. Significant coherence values were found above 0.5 Hz. The estimation of frequency response function revealed the dominant resonance frequencies between 0.60 Hz and 0.68 Hz. On the basis of our results illustrated here, the linear model of standing postural control was further concluded.

비대면 설계교과목의 학습성과(PO) 평가체계 개발 (A Development of Program Outcome(PO) Evaluation System of Non-face-to-face Capstone Design)

  • 이규녀;박기문;최지은;권영미
    • 공학교육연구
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    • 제24권4호
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    • pp.21-29
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    • 2021
  • The objective of this research is to devise a BARS evaluation system as a performance evaluation plan for non-face-to-face capstone design and to verify the validity through the expert FGI as the remote education is highlighted as a new normal standard in the post corona epoch. The conclusion of this research is as follows. First, the non-face-to-face capstone design is a competency centered subject that allows you to develop the engineering and majoring knowledge and its function and attitude, and the achievement of program outcome is the objective competency, and the researcher proposes the BARS method evaluation, one of competency evaluation method, as a new performance evaluation plan. Second, for the evaluation of PO achievement of non-face-to-face capstone design, the researcher deduced 20 behavior identification standard(anchor) of BARS evaluation system, and developed the achievement standard per 4 levels. Third, as the evaluation tool of non-face-to-face capstone design, the presentation data(PPT), presentation video, product such as trial product(model), non-face-to-face class participation video, discussion participating video, team activity report, and result report for the evidential data of BARS evaluation were appeared as proper. Finally, the BARS evaluation plan of non-face-to-face capstone design would be efficiently made through the establishment of evaluation plan, the establishment of grading standard of BARS evaluation scale, the determination of evaluation subject and online BARS evaluation site.

중풍 환자의 경직에 있어서 전침 치료 효과에 대한 체계적 고찰 (Systematic Review of Efficacy of Electroacupuncture for Spasticity because of Stroke)

  • 고호연;공경환;신미란;장명웅;박선주;박정수;장보형;이주아;고성규;전찬용
    • 대한중풍순환신경학회지
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    • 제12권1호
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    • pp.61-67
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    • 2011
  • Background : Prevalence of spasticity because of stroke are 40% patients after 12 month. Spasticity caused decrease of range of motor, motor function, and active daily living. Electroacupuncture widely used stroke. But it is been studied by systematic review between spasticity and electroacupuncture. This study is aimed to efficacy of electroacupuncture for spasticity because of stroke. Methods : We had used pubmed(www.pubmed.com) and cochrane library(www.thecochranelibrary.com) database. Limits are'human','randomized controlled trial'and'all adult 19+ years'in pubmed. The period was until 15, september, 2011. We used MeSH(Medical Subject Headings terms. The search words were'stroke'[mesh],'muscle spasticity'[mesh and 'electroacupuncture'[mesh]. In cochrane library, we used spasticity and electroacupuncture in cochrane library. We found 19 studies. But only 3 studies were included for inclusion criteria. Results : The appropriate 3 studies were different from subject, acupoint, duration of treatment, endpoint and etc. But these studies were effective for spasticity because of stroke. Conclusion : These studies were not meta analysis because of heterogeneity. But the above results might explain the electroacupuncture were effective for spasticity and further study needed to verify and standard electroacupuncture study for spasticity.

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장기이식 전문간호사의 직무분석 (Task Analysis of Korean Transplantation Nurse Practitioner)

  • 변수자;김희경;김애리;하희선;전경옥
    • 대한간호학회지
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    • 제33권2호
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    • pp.179-188
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    • 2003
  • Purpose: This study was designed to create the job description of Korean transplantation nurse practitioner and examine performance frequencies, criticality, and difficulties of task elements. Method: The sample consisted of 63 nurses and coordinators who performed duties related to transplantation at medical center in Korea. A survey method was used, and the questionnaire included frequencies, criticality, and difficulties of task elements in job description by the DACUM method. Using SPSS WIN 10.0, descriptive statistics such as frequency distribution, means, and standard deviations were conducted to examine the subject's general characteristics, the frequencies, criticality, and difficulties of task performance. Result: The job description of transplantation nurse practitioners revealed 5 duties, 22 tasks, and 85 task elements. On the all five duties, the averages of the performance frequency, criticality, and difficulty were 2.41, 3.38, and 2.78, meaning that the respondents rarely perform the 5 duties, but consider them critical and easy to perform. Conclusion: The job description of the transplantation nurse practitioner included duty, task, and task element and definition of job completed. Thus we recommended a data based trial to confirm and validate the information gathered.

이동 하중의 질량효과를 고려한 보의 동적응답 (Dynamic Response of a Beam Including the Mass Effect of the Moving Loads)

  • 최교준;김용철
    • 대한기계학회논문집
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    • 제15권1호
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    • pp.61-68
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    • 1991
  • 본 연구에서는 스프링힌지, 클램프, 단순지지, 탄성지반, 다수의 병진 및 회 전스프링 그리고 중간지지점의 조합으로 구성되어 있는 보에 대하여 우선 Hamilton원 리에 의하여 정확한 보의 특성방정식을 유도하고 모든 경계조건을 만족하는 직교다항 식을 구한 후, 스프링, 댐퍼로 구성된 여러개의 질량이 일정한 속도로 이동할 경우에 대하여 Galerkin방법과 수치적분 방법을 사용하여 동적응답을 구하였다. 또한 구속 조건 및 경계조건이 변함에 따라 동적응답에 미치는 영향을 연구하였다.

몸통 운동시 지향각(Orientation angles)을 이용한 허리 근육의 3차원 위치 좌표 추정 기법 (The method to estimate 3-D coordinates of lower trunk muscles using orientation angles during a motion)

  • 임영태
    • 한국운동역학회지
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    • 제12권1호
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    • pp.125-133
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    • 2002
  • The purpose of this study was to develop a method for estimating 3-D coordinates of lower trunk muscles using orientation angles during a motion. Traditional 3-D motion analysis system with DLT technique was used to track down the locations of eight reference markers which were attached on the back of the subject. In order to estimate the orientations of individual lumbar vertebrae and musculoskeletal parameters of the lower trunk muscle, the rotation matrix of the middle trunk reference frame relative to the lower trunk reference frame was determined and the angular locations of individual lumbar vertebrae were estimated by partitioning the orientation angles (Cardan angles) that represent the relative angles between the rotations of the middle and lower trunks. When the orientation angles of individual intervertebral joints were known at a given instant, the instantaneous coordinates of the origin and insertion for all selected muscles relative to the L5 local reference frame were obtained by applying the transformation matrix to the original coordinates which were relative to a local reference frame (S1, L4, L3, L2, or L1) in a rotation sequence about the Z-, X- and Y-axes. The multiplication of transformation matrices was performed to estimate the geometry and kinematics of all selected muscles. The time histories of the 3-D coordinates of the origin and insertion of all selected muscles relative to the center of the L4-L5 motion segment were determined for each trial.