• Title/Summary/Keyword: Trial

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Comparative Analysis of Refractive Power on Trial Case Lenses (검안렌즈의 굴절력 비교 분석)

  • Moon, Byeong-Yeon
    • Journal of Korean Ophthalmic Optics Society
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    • v.17 no.4
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    • pp.321-334
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    • 2012
  • Purpose: In this study, the distribution and differences in refractive powers on trial case lenses were investigated. Methods: We measured refractive powers at optical center and periphery using 4 trial case lens sets. According to international standards, the distribution and uniformity in refractive powers were investigated. Results: The lens shapes were different in different kinds of trial case lenses and some of lenses were out of tolerance according international standards. In some cases, the power differences were found between front and back side as well as between optical center and peripheral regions and also the cylindrical power on spherical lens and spherical power on the cylindrical lens were measured. Conclusions: Trial case lens are used to assess the refractive error, therefore, more precise control of the manufacturing process for trial case lenses and more thorough quality control will be required to offer an accurate vision test. More careful attention in using trial case lens is also required.

Safety and Effectiveness of Fluoroscopy-Guided Acupotomy for Carpal Tunnel Syndrome: Protocol for a Pilot Randomized, Patient-Assessor Blind, Parallel Clinical Trial

  • Yang, Muhack;Kim, Jae Kyoun;Park, Gun Woo;Cha, Eunhye;Jang, Jongwon;Seo, Jihye;Lee, Sangkwan;Kim, Sungchul
    • Journal of Acupuncture Research
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    • v.36 no.2
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    • pp.100-106
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    • 2019
  • Background: In Korean medicine, carpal tunnel syndrome is treated by stimulating the acupoints around the wrist. Although a deep understanding of anatomy and guidance is needed to stimulate these acupoints to avoid undesirable side-effects, currently there are no published guidelines for acupotomy treatment. The aim of this study is to evaluate the effectiveness and safety of fluoroscopy-guided acupotomy compared with conventional acupotomy treatment. Methods: This is a randomized, patient-assessor, patient blind, parallel clinical trial. A total of 30 patients will be enrolled at Wonkwang University Gwangju Hospital, and will be allocated to either an experimental group or a control group. The experimental group will be treated using fluoroscopy-guided acupotomy and the control group will be treated using the conventional acupotomy method. Results: The primary outcome measure will be identification of a cross-section area of the median nerve measured by ultrasonography, and the secondary outcome measure will be the alleviation of pain measured by the Visual Analogue Scale, improvement in the Nerve Conduction Study, Tinel test, Phalen's test, EuroQol 5-dimension scale, and Boston Carpal Tunnel Questionnaire score. Safety components will be measured by monitoring vital signs, electrocardiographs, blood tests, general chemical tests, urine tests and pregnancy tests. In addition, observations for adverse effects will be performed during the trial. Conclusion: This study will provide a more effective, and less harmful way of treating carpal tunnel syndrome compared with conventional acupotomy. Fluoroscopy-guided acupotomy will help practitioners to be accurate in direction and depth of the needle for treating carpal tunnel syndrome.

Speed Control of tne Induction Motor Using SCR (Trial Manufacturing of Solid-state Frequency Converter) (SCR를 이용한 유도전동기의 속도제어에 관한 연구)

  • Jong Swoo Won
    • 전기의세계
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    • v.19 no.4
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    • pp.1-11
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    • 1970
  • It is well known that solid-state devices like inverter and converter made by transistor and other semi-conductors are widely used for the purpose of motor speed control in industrial fields. This paper is devoted primarily to a study of Trial Manufacturing of Solid-state Frequency Converter by means of single-phase bridge-type SCR inverter. The principle of the trial product belongs to AC-DC-AC conversion system. The voltage to be impressed to the motor in case of speed control by frequency conversion method is necessary to be proportional to frequency. It also requires the frequency and voltage are independent to hte load variation. In order to meet above requests required to motor speed control., the trial product introduced the open loop system in the frequency setting and closed loop system in the voltage setting. The trial product showed the favorable performance characteristics in speed control of singlephase fractional horsepower motor from 45HZ through 80HZ.

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The Study on the Effect of Dohongsamultang and Dansameum on Restrain of Thorombus Formation (도홍사물탕(桃紅四物湯) 및 단삼음(丹蔘飮)이 혈전생성억제(血栓生成抑制)에 미치는 영향(影響))

  • Sin, Dae-Cheol;Kim, Yeong-Gyun
    • The Journal of Internal Korean Medicine
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    • v.16 no.2
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    • pp.136-145
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    • 1995
  • In order to investigate the effect of Dohongsamultang and Dansameum upon restrain of thorombus formation through the experimental study, following conclusion has been obtained; 1. The number of plateletes was increased in the trial group compared with the control group, revealed significance in both of trial groups. 2. Fibrinogen was increased in trial group compared with control group, but the significance was revealed only in Sample I group of Dohongsamultang. 3. Prothrombin time was shortened in both of trial groups, but the significance was revealed in Sample I group of Dohongsa-multang. 4. FDP was decreased in both of trial groups, but the significance was revealed in Sample I group of Dohongsamultang.

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A Trial Excavation of Underwater Cultural Properties at Dongsam Site, Busan (부산 동삼지구 수중문화재 시굴조사)

  • Kim, Jin-Hoo;Kim, Hyun-Do
    • Proceedings of the Korean Society of Marine Engineers Conference
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    • 2005.11a
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    • pp.154-155
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    • 2005
  • A trial excavation of underwater cultural properties at Dongsam site in Busan has been conducted. The site is located in the vicinity of Dongsam shell mound. The trial excavation consists of the shore investigation and the underwater investigation. For the shore investigation four trenches were digged. For the underwater investigation twenty boreholes were cored, and sediments at four predetermined sites were removed by air lifting technique. From the trial excavation a stump of a tree with many pieces of wood, and a few fragments of earthenwares were found. A comprehensive study of the trail excavation might furnish data for studying ancient coastal environment.

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Trends of clinical trials from 2014 to 2016 in South Korea

  • Huh, Ki Young;Hwang, Jun Gi;Lee, SeungHwan
    • Translational and Clinical Pharmacology
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    • v.26 no.4
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    • pp.172-176
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    • 2018
  • Mandatory registration of clinical trials in public registry can ensure the transparency of clinical trials. Public clinical trial registry of can provide current chronological and geographical distribution of clinical trial throughout the country. We used public clinical trial registry provided by Ministry of Food and Drug Safety to analyze current status of clinical trial from 2014 to 2016 in South Korea. The number of clinical trials in antineoplastic and immunomodulating agents area was the greatest, followed by cardiovascular system and antiinfectives for systemic use as a whole. From 2014 to 2016, overall number of clinical trials decreased while the number of phase I clinical trials increased. Seoul accounted for more than half number of clinical trials in Korea. Supports for clinical trials in non-metropolitan area needs to be considered.

Bioequivalence trial with two generic drugs in 2 × 3 crossover design with missing data

  • Park, Sang-Gue;Kim, Seunghyo;Choi, Ikjoon
    • Communications for Statistical Applications and Methods
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    • v.27 no.6
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    • pp.641-647
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    • 2020
  • The 2 × 3 crossover design, a modified version of the 3 × 3 crossover design, is considered to compare the bioavailability of two generic candidates with a reference drug. The 2 × 3 crossover design is more economically favorable due to decrease in the number of sequences, rather than conducting a 3×3 crossover trial or two separate 2 × 2 crossover trials. However, when using a higher-order crossover trial, the risk of drop-outs and withdrawals of subjects increases, so the suitable statistical inferences for missing data is needed. The bioequivalence model of a of 2×3 crossover trial with missing data is defined and the statistical procedures of assessing bioequivalence is proposed. An illustrated example of the 2 × 3 trial with missing data is also presented with discussion.

The sea Trial of Deep-sea Crabster CR6000 System (심해용 크랩스터 CR6000 시스템의 실해역 시험 결과)

  • Jun, Bong-Huan;Yoo, Seong-Yeol;Lee, Pan-Mook;Park, Jin-Yeong;Shim, Hyungwon;Baek, Hyuk
    • IEMEK Journal of Embedded Systems and Applications
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    • v.12 no.5
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    • pp.331-341
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    • 2017
  • This paper presents the sea-trial results of Crabster CR6000 which is a deep-sea walking robot developed by KRISO in 2016. Crabster CR6000 is designed to inspect deep-sea environment rejecting the disturbance on the silent and calm abyssal area. The sea-trial was conducted at the East Sea and the Philippine Sea on December 2016. The Crabster CR6000 undocked successfully from the Shuttle after touchdown on the sea-bed and walked out on the soft sediment soil of the 4,743m seafloor at the fourth diving in the Philippine Sea. The advanced technologies and capabilities of CR6000 were verified from the operational and functional test conducted in the sea-trial. The experimental data acquired from the sea-trial were summarized and the first experience of the deep-sea walking robot was presented in this paper.

A Case Report of Nasopharyngeal Endoscopic Biofeedback Trial Therapy for Patients with Velopharyngeal Inadequecy (구개인두기능 부전 환자의 코인두 내시경을 이용한 생체되먹임 시험 치료 치험례)

  • Kim, Jae-Gon;Park, Mi-Kyong;Baek, Rong-Min
    • Archives of Plastic Surgery
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    • v.38 no.6
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    • pp.867-870
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    • 2011
  • Purpose: The authors would like to introduce two patients who presented with velopharyngeal inadequacy. We emphasize the importance of nasaopharyngeal endoscopy in evaluating the velopharyngeal function and the usefulness of biofeedback trial therapy. Methods: Two patients visited our clinic due to velopharyngeal inadequacy. Both of the patients showed hypernasality, nasal emission and compensatory articulation such as glottal stop. During oral examination and nasopharyngeal endoscopy both showed no evidence of structural deformities. One inconsistently showed a small gap during articulation. The other showed a rather large gap during compensatory articulation. Both received a simultaneous biofeedback trial therapy using the nasopharyngeal endoscope. Results: Both patients were successfully diagnosed and treated at once using biofeedback trial therapy with nasopharyngeal endoscopy. By giving direct visual feedback to the patient, they were both able to achieve complete velopharyngeal closure during production of 2~3 nonsence syllables and hypernasality was not detected in both of them. Conclusion: The authors were able to help patients with velopharyngeal inadequacy to have velopharyngeal closure through biofeedback trial therapy. The accurate evaluation of velopharyngeal function and the possibility of closure prevented unnecessary operations.